Gene kin-26 (Nematode worm)

kin-26

Species: Nematode worm
Alias: Cehd-22, CE04904, kin-26, T06C10.6, aSWK369
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 7877791-7875741, WormBase Genetic Map location: n/a,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
kin-26.AA Protein Genbank 433 None Fasta, JSON
kin-26.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of kin-26.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 kin-26.AA SH2 18-107 32 1.5e-24 88.8 SMART 1-87 (87) Show / Hide 
Range on Protein: 18-107
Range on HMM: 1-87/87
Sequence Identity: 32% (32 aa)

ELYYHGLLPSEDVRQLLSNN----GDFLLRSSEPEPGSPRTHILSVMFNNRLDDINSIKHFVVNFVD-GKYFIND--KMSFPSIQKMLGTYQRNNTE
. .||| .. |.. ||| |.    ||||.| ||.   .|.  .|||...      . .||....  | |||.| .  ...|||.  ..  ||.|   
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWK------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 kin-26.AA SH2 20-101 29 1.3e-18 56.48 Pfam 1-81 (81) Show / Hide 
Range on Protein: 20-101
Range on HMM: 1-81/81
Sequence Identity: 29% (26 aa)

YYHGLLPSEDVRQLLSN----NGDFLLRSSEPEPGSPRTHILSVMFNNRLDDINSIKHFVVNFVDGK-YFINDKMSFPSIQKMLGTY
.||| .. ... .|| |    .|.||.| || .||.     |||.....   ....||..... |.. |.| ..  |.|.| .   |
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD---YTLSVRDDGP---GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase kin-26.AA Fer 130-384 48 1.1e-144 486.98 In-house 1-283 (283) Show / Hide 
Range on Protein: 130-384
Range on HMM: 1-283/283
Sequence Identity: 48% (136 aa)

ITIHKKLGEGAFGEVSSG--VMKFKKGMKTVQ--VAIKQVKL--DKTGKAKIKDFLAEARTMRK-LGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFL
.|..||||||||||| .|  ..|.|||.. |.  ||.|..|.  ....|..||.|..||| ||. . | |..||||| |...|...|||.. .|.|||.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KKNED--LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGKVK----ISDFGLTRN----GTVYQIK-PNTKSPIRWLAIETIKTMICSEKTD
|||..  .|...| .|..|||.|.||.|.| ..|||||||||||...|||    |||||. |.    |. |. | . .| |||||| ||..|.|.|.|||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWAYGVLCWEIFNNAAEPYPG----MKPADV-----ATQVANGYRMPPYPHAQAEIQTMMA-RCNAENPNDRPSMAEIAEILQ
||..||.|||||.|.||||||    ||.. |     .  . .||.||. .|.  ||   |. .| ...|.|||.|.|| ..| 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase kin-26.AA TyrKc 130-383 39 1.1e-123 418.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-280/280
Sequence Identity: 39% (114 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKL--GHQNIIKFYGVGVLQ-------EPLYLVMELAVNGALDS
||  |||||||||||  |..|       .|||.| .| |.     ..||. ||| |.||   |.||...||| . |       |||..|||.. .|.|..
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FLKKNED-LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGK-VKISDFGLTRNGTVY--------QIKP----NTK--SPIRWLAIETIKTM
.|.|... |..... .. .|.| | ||.| |.  |||.||||||..... ||||||||.|... .         ...    ..|   ||||.|.|.|.. 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

ICSEKTDVWAYGVLCWEIFNNAAEPYPG-----MKPADVATQVANGYRMPPYPH--------AQAEIQTMMARCNAENPNDRPSMAEIAEIL
....|.|||..||..|||| . ..||||     |....|  .| .|||||. |.        . .|. ..| .| .|.|.|||...|| |..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase kin-26.AA Pkinase_Tyr 130-383 39 4.5e-115 390.36 Pfam 1-270 (270) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-270/270
Sequence Identity: 39% (108 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAK--IKDFLAEARTMRKL-GHQNIIKFYGVGV-LQEP--LYLVMELAVNGALDSFLK
||. |||||||||||  |..| ... ....||.| .  ... .    ..||..||..|..|  |.||...||| .  .||  .|.|||.. .| |...|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----NEDLSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYT-DGKVKISDFGLTRNG---TVY-QIKPNTKSPIRWLAIETIKTMICSEKTDVWA
|    .. |..  . .| .| |.|.|| . |.. |||.|||||| | ...|||.||||.|       | . . ..| ||.|.| | |.......|.|||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGVLCWEIFNNAAEP-YPGMKPADVATQV-ANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEIL
.|||.||||   ..| ||||....|  ..  .|||||. ... .|| ..| .| ...|.|||...|| |.|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase kin-26.AA TK 130-383 21 2.2e-99 333.84 In-house 1-486 (486) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-486/486
Sequence Identity: 21% (107 aa)

ITIHKKLGEGAFG---EVSSG---------------------VMKFKKGMKTVQVAIKQVKLD--KTGKAKIK----------DFLAEARTMRKLG----
||. ||||||.||   ||  |                      .|..|......||.|..|..   . ....           |||.||. | ..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HQNIIKFYG-------------VGVLQEPLYLVMELAVNGA----LDSFLKKNED--------------------------------------------
 |.||...||             | |.|||...|||.. .|     |...|.|. .                                            
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LSVDKKTEMILQAAWGLEYIHGKP------MLHRDIAARNCLYTDGK------------VKISDFGLT
                                |..  .  | .|.| |.||.| |.      . |||.|||||| ....            .||.||||.
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

RNGT-----------------------------------VYQIKPNTKSPIRWLAIETIK---------TMICSEKTDVWAYGVLCWEIFNNAAEPYPGM
|.|.                                    |  ....| ||||.| |...         . ....|.|||..|||.|||| ...|||.|.
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

KP----------ADVATQVANG--------------YRMPPYPHAQ--------------AEIQTMMARCNAENPNDRPSMAEIAEIL
 .          ..|  .. .|              .|||. ||.               .|.. .| .| ...|.|||..... | |
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase kin-26.AA UTK 130-383 30 6.5e-78 265.16 In-house 1-296 (296) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-296/296
Sequence Identity: 30% (89 aa)

ITIHKKLGEGAFGEVSSGVMKFKK-GMKTVQVAIKQVKLDKTGKAKIK---DFLAEAR---TMRKLG-HQNIIKFYGVGVLQEPLYLVMELAVNGALDSF
. . ..||.||||||. .  .. .  |....||.|. . ....  .     ||. |||    | ..  |.|.....|| . .||...|.|...|| |.|.
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LKKNED--------LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDG--------KVKISDFG---LTRNGT------------VYQIKPNTK
| .. .        |. .....| .. | |..|.|..   |||.|||||| ..         ..||.|||   ..|.               |.  ....
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

SPIRWLAIETIKTM-ICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANG--YRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEIL
 |||| | | .  .   ..|.|||..||.||||. ... |||||  ..|..|| ||  ||||. ..  ... ..| || . .| .||.. .. . .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase kin-26.AA TK-Unique 130-383 33 1.5e-64 220.77 In-house 1-294 (294) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-294/294
Sequence Identity: 33% (98 aa)

ITIHKKLGEGAFGEVSSGVMKF--KKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKLG-HQNIIKFYGVGVLQ-EPLYLVMELAVNGALDSFLKKN
... ...||||||.|  | ..   |.  |...||.|..| . |.  . .||| |.. |..|| |.||....|. .   || ...|| . .| |...|...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDT-DKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

EDL-----------------SVDKKTE---------MILQAAWGLEYIHG--KPMLHRDIAARNCLYT-DGKVKISDFGLTR---NGTVYQIK-PNTKSP
 .                    .. ||          . | | |.||...  |   |||..|||.| | |...||.|||..|   ...||. .    . |
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

IRWLAIETIK--TMIC-SEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHA-QAEIQTMMARCNAENPNDRPSMAEIAEIL
|||.| | .|  . .. ..|.|||..||| |||| . | |||||...|. ... .|||||  .|    |.   | .|  ..| .||| ..|. .|
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase kin-26.AA Src 130-383 33 2.3e-60 203.79 In-house 1-255 (255) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-255/255
Sequence Identity: 33% (89 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLK---KNE
|.  .|||.| ||||  |. .     ....||.|  | .     . ..||.|| .| || |..... | |    || | | |.  .| |  .||   .  
IKLCRKLGQGQFGEVWMGYWN-----GNTKVAVKTLKPGT---MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

DLSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGK-VKISDFGLTRNGT----VYQIKPNTKSPIRWLAIETIKTMICSEKTDVWAYGVLCWE
 |.. .  .|  | | | .|.  . . ||| |||| |  ..  .|. |||| |       .|  .   | ||.| | | |     . |.||| .|.| .|
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE

IFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQT-MMARCNAENPNDRPSMAEIAEIL
|.     |||||. ..| .|| .|||||  ..  .|.    | .|  . | .||  . . . |
IVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase kin-26.AA Abl 130-383 33 8.8e-58 191.12 In-house 1-252 (252) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-252/252
Sequence Identity: 33% (88 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLKKNEDLS
|....||| | .|||  || |         ||.| .| |     ....||.||  |... |.|...  ||     | |.. |   .| |  .|....  .
IMMKHKLGGGQYGEVYEGVWK----RHDCTVAVKTLKED---TMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREE

VDKKT--EMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGK-VKISDFGLTR--NGTVYQIKPNTKSPIRWLAIETIKTMICSEKTDVWAYGVLCWEIFN
..  .   |  | | |..|.  .  .|||.||||||  . . ||. ||||.|  .. .|  .   | ||.| | | .     | | ||||.||| |||  
LPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIAT

NAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEIL
    ||||.   .|  .. .||||   .    ..  .| .|   .. |||| .|| . .
YGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase kin-26.AA Frk 130-387 33 2e-54 186.94 In-house 1-260 (260) Show / Hide 
Range on Protein: 130-387
Range on HMM: 1-260/260
Sequence Identity: 33% (91 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLK----KN
| . ..|| | ||||  |         |. ||.|..   |.| .  .|||.||. |.|| |  .|. | |  ..||.|.. ||  .|.|  .|.    | 
IQLIRRLGSGQFGEVWEGLWN-----NTTPVAVKTL---KPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKG

EDLSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGK-VKISDFGLTR-----NGTVYQIKPNTKSPIRWLAIETIKTMICSEKTDVWAYGVLC
. . . .  .|  | | |. |.  .  .|||.|||| |  ... .|| |||| |     |  .|  . . . ||.| | | ...   . | |||..|.| 
RQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILL

WEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEILQRVT
 ||      |||||  |.| ..|..|||||  |  . ..  .|  |  ..|. ||    .   |.   
TEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase kin-26.AA Ack 130-383 34 2.6e-54 181.59 In-house 1-266 (266) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-266/266
Sequence Identity: 34% (92 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAK--IKDFLAEARTMRKLGHQNIIKFYGVGVLQEPL-YLVMELAVNGALDSFLKKNE
|| ..|||.| || |  |. .   | |..|||.| .. |  ...   . ||| |. .| .| | .... ||| ||  |.  .|.|||  |.|   |.|  
ITLCEKLGDGCFGVVWRGEWTN-PGGKHIQVAVKCLRSD-KMQQPNCMDDFLREVAIMHSLDHPHLVRLYGV-VLDQPMLMMVTELAPCGSLLDCLRKHC

D---LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDG--KVKISDFGLTR----NGTVYQIKPNT--KSPIRWLAIETIKTMICSEKTDVWAY
    ...    .  .| | |. | . | ..||| |||| |   .  ||||.|||| |    |   |  ...   | |. | | | ...   | . |||..
RTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMF

GVLCWEIFNNAAEPYPGMKPADVATQVA-NGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEIL
||  || |    ||. |. ....  ..  .| | |  ..   .| .|| .| ...| |||. ..| . |
GVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase kin-26.AA Eph 130-383 36 3.2e-51 170.26 In-house 1-264 (264) Show / Hide 
Range on Protein: 130-383
Range on HMM: 1-264/264
Sequence Identity: 36% (97 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTV---QVAIKQVKLDKTGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLKKNE
|.| | .|.| |||| .| .| ..| . |    ||||  |   | |... |||.|| .|    | |||.  ||   ..|.  | |   ||.|||||....
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRW-DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD

D-LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGKV-KISDFGLTRN-------GTVYQIKPNTKSPIRWLAIETIKTMICSEKTDVWAYGV
. ..| . ..|.   | |  |       ||| |||| |     | |.|||||.|          .|  .   |.|||| | |.|   . .   ||| ||.
GQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGI

LCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEIL
. ||.      ||  |   ||   .  ||| || .   . .  .|  | .  .|.||  ..|  ||
VMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase kin-26.AA SrcB 130-384 35 4.7e-50 167.48 In-house 1-251 (251) Show / Hide 
Range on Protein: 130-384
Range on HMM: 1-251/251
Sequence Identity: 35% (93 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLKKNE--D
. . |||| | ||||  |  .     . ..||.| .   | |   .. |||||  |..| |. ... | | | .||.|.. |   .|.|  ||| .|   
LKLVKKLGAGQFGEVWMGYYN-----NHMKVAVKTM---KQGTMSPEAFLAEANVMKTLQHDRLVRLYAV-VTKEPIYIITEYMAKGCLLDFLKTDEGSK

LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGKV-KISDFGLTRNGTV--YQIKPNTKSPIRWLAIETIKTMICSEKTDVWAYGVLCWEIFN
||..|  .|  | | |. ||  .  .|||. | | |  .  . || |||| |      |  .   | ||.| | | |.  .   |.|||..|.|  ||  
LSLPKLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVT

NAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEILQ
    |||||  ..| ...  |||||       |.  .|..|  | | .||    .  .|.
YGRIPYPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase kin-26.AA S_TKc 130-387 23 1.4e-35 125.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 130-387
Range on HMM: 1-231/231
Sequence Identity: 23% (63 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVN--GALDSFLKKNED
 .|..|.|.||||.|  .. |        .||||..|         .... | . ..| .| ||.|.|.| .  . ||.|||.. .  | | ...||.  
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDGKVKISDFGLTRNGTVYQIKPNTKSPIRWLAIETIKTMICSE-KTDVWAYGVLCW
      ..      .. | . .|||.| .  .|||.   | | ..  .||.|||| |                ..| | .     .  | |.|. |.. .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAE-----ILQRVT
| .     |.|     ..  ..              |   .. .|   .|..||.  |. .      .    
EMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase kin-26.AA Pkinase 130-386 21 4.3e-26 93.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 130-386
Range on HMM: 1-293/293
Sequence Identity: 21% (66 aa)

ITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIKDFLA--EARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNG----ALDSFLK
..|..|.|.|.||.|    .. . |    .||.|..|.... . | .  .   |.. |..|.| ||...|..      .|.|||.. .|     | ....
YHIGRKIGSGSFGCV-YKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--KNEDL--SVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYT-DGKV----KISDFGLTRN--GTVYQIKPNTKSPIRWLAIETIK-TMICSEKTD
  ..  .  | .    ...| . ||||.| .  .|||.   |.|.  .| .    ||.|||| .      ..        ....| | |.     . | |
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VWAYGVLCWEIFNNAAEPYPGM----KPADVATQVANGYRMPPYPHAQ-----------------------AEIQTMMARCNAENPNDRPSMAEIAEILQ
.|..|....| ..    |.||     . .|    ...  . |.  . .                        | .  . .| . .|..||.   ...|||
MWSCGCILYEMLCGR-PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQ

R--V
   .
HPWF