Gene kin-1 (Nematode worm)

kin-1

Species: Nematode worm
Alias: CE15475, ZK909.2a, PKAC, aSWK012, kin-1, ZK909.2b
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: No interpolated position., WormBase Physical Map location: I: 14941839-14959488,

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
kin-1.AA Protein Genbank 375 None Fasta, JSON
kin-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of kin-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase kin-1.AA PKA 52-306 69 2.6e-211 708.31 In-house 1-263 (263) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-263/263
Sequence Identity: 69% (184 aa)

FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVN-MTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEP
|..|.||||||||||||..||.||||||||.|.||..|.||||||..|||.|||.|..||.|. | ..|.|...||||.|...||||||.||. ||||.|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

HSRFYAA-QIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSK-GYNKAVDWWALGVLIYEMAAGYPPFF
|..|||| |||||.|||||...|||||||||.|||. |..|||||||||.|..|||||||||||||||||.|| |..|.|||||||.|||||.||||||.
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

AD--QPIQIYEKIVSGKVKFPSHFSNEL---KDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
..  .|.||||||..||.|||.||.. .   |||.|.||||||||||||.|||| ||||||||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase kin-1.AA AGC 52-306 35 4.5e-195 510.13 In-house 1-395 (395) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-395/395
Sequence Identity: 35% (140 aa)

FDRIKTLGTGSFGRVMLVKHK------QSGNYYAMKILDKQK-VVKLK--QVEHTLNE------------KRILQAID----------FPFLVN-MTFSF
|. .|..|.||||.|.||..|      ..| |||||.|.|.. .|..|  .||||..|            ..||. ..           ||.|. . .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDNSN--LYMVLEFIS---------GG-EMFSHLR---RIGRFSEPHSRFYAAQ-------IVLAFEYLHS-LDLIYRD-LKPENLLIDSTGYLKITDFG
.|...  ||.|.|...         || |.|.||.   . |||.|...|||||.       ||||.||||| .. |.|| |||||.|.|. |..|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKRVKG-----------------------------------------------------RTWTLCG--TPEYLAPEIILSKGYNKAVDWWA--LGVLIY
..|....                                                     ||||.||  ||||.||||.    |.||.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMAAGYPPFFAD----------QPIQIYEKIV------SGKVKFP----------SHFSNELKDLLKNLLQVDLTKRYGNLKN-----GVADIKNHKWF
|| .|||||..|          .| ....||       . |||||          ..||.|.|||.| ||..| .|| |...|     |. .||||.||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase kin-1.AA Akt 52-306 49 4e-143 460.4 In-house 1-264 (264) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-264/264
Sequence Identity: 49% (131 aa)

FDRIKTLGTGSFGRVMLVKHKQSGNYY-AMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEP
|| .| || ||||.|.||| |.....| |||.| |.. .. .|||||. |..||| ...||.||. .|| .. .||.|.....||| |.||.| .||||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

HSRFYAAQIVLAFEYLHSLDLIYRD-LKPENLLIDSTGYLKITDFGFAK-R-VKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWA-LGVLIYEMAAGY
  |||.|.|.|| |.||| . |||| |||||.|.|..|....|||| .|   .|   .| |.|||||||||||.. .|. ||||||. ||...|||  | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFFADQPIQIYEKIVSGKVKFP--SHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
|||....  | ..|| ...||||  . .|.| |||.. ||. | .|| |. .|.. .||.| ||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase kin-1.AA SGK 52-306 42 3.5e-134 417.0 In-house 1-283 (283) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-283/283
Sequence Identity: 42% (121 aa)

FDRIKTLGTGSFGRVMLVKHKQS------------------GNYYAMKILDKQKVV-------KLKQVEHTLNEK-RILQAIDFPFLVNMTFSFKDNSNL
|| .|..| ||||.|..||||.                   .  ||||.| || ..       | |.. |.. |.  ||. .  ||.||  ..|     |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAK---RVKGRTWTLCGTPEYLAPEIILSK
|.|.... |||||.||.| ..|.|. .|||||.||.| |||||.| |||||||||.| |. |....|||| .|     .  | | ||||||||||... .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
.. ..|||| || . |||  | |||.     | |..| ... ..|  .||. .||.. ||| | .|| |  |.. ..|||| .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF
Kinase kin-1.AA AktR 52-306 44 4.7e-133 448.33 In-house 1-268 (268) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-268/268
Sequence Identity: 44% (119 aa)

FDRIKTLGTGSFGRVMLVKHK-QSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQ-AIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSE
|...| || | ||.|.||..| ... .||||...|.| ....| .||..|. |..  ...||.|.. ..|.....|. ..|.. |||.|.||.....|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PHSRFYAAQIVLAFEYLHSL-DLIYRDLKPENLLIDSTGYLKITDFGFAK----R-VKGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAA
  .|||.|||.||.||||.  . |||||||||.|.|. |..|||||| .|    .    .. ..||||||.|||.|.  ||.||.|||||.|..|||| .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYPPFFADQPIQIYEKIVSGK-VKFPSH--FSNELKDLLK-NLLQVDLTKRYGNLKNGVADIKNHKWF
|.|||....  |...|| .   .||| .  ||...|||..  ||. . .|| |  .||  .||.|.||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase kin-1.AA Ciliate-E2b 52-306 37 7e-112 341.18 In-house 1-272 (272) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-272/272
Sequence Identity: 37% (104 aa)

FDRIKTLGTGSFGRVMLVKH-KQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIG--RFS
.. || || | || | ||.  |.. .|||||   | ....     | |.|| .|. ...||...   ||||. ..|...||..|.|.|. .| ||   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

EPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVK---G---RTWTLCGTPEYLAPEIIL-----SKGYNKAVDWWALGVLI
.  |.|| |.|.|..||||..  ||||.|||| ..|..||.|. |.| ||  .   .   || |..|||.|.|||||       |||. .|| |..|.  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YEMAAGYPPFF--ADQPIQIYEKIVSG--KVKFPSHFSNELK------DLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
||.  ||.|.   .. |..||..|...  ...|||.......       .|.   .|.| ..|. |       |.|.||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWL-------KSHPWF
Kinase kin-1.AA RSK 55-306 39 2e-109 369.81 In-house 1-278 (278) Show / Hide 
Range on Protein: 55-306
Range on HMM: 1-278/278
Sequence Identity: 39% (111 aa)

IKTLGTGSFGRVMLVKHK---QSGNYYAMKILDKQKVVKLKQ-VEHTLNEKRILQAID-FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGR---
.| ||.|..| | |.. .   ..| .||||.|.| |.|. .  ..||. | .||...   ||.|.   .|.... ||...|...|||.| ||.. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDS---TGYLKITDFGFAKRV----KGRTWTLCGTPEYLAPEIIL----SKGYNKAVDWWALGV
|||   .||.|.|||| |.||... |.||||||| | |.    | .|.|||||.|      ...| | |.| ||.|||..      .|..||.||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMAAGYPPFFA---DQPIQIYEKIVSGK--VKFP--SHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
|.||| .|.||| .   ... .| ..| .||  ...|  .  |.| |||.. .|..|  ||.|  ......||.|.||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase kin-1.AA PKG 52-306 44 5.70000000001e-109 368.33 In-house 1-260 (260) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-260/260
Sequence Identity: 44% (115 aa)

FDRIKTLGTGSFGRVMLVKHKQ-SGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEP
...| ||| | |||| ||. .. .   .|.|.. |. .|. .| ||  .||.|..  . .| | .   |.|.  .|| .|   |||. . ||  |.| ..
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

HSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
 .|||.| .| ||.|||.  .||||||||||. | .||.|. ||||||...  ..||| |||||| |||||| ||   .||.||||.|..|   | ||| 
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

ADQPIQIYEKIVSG--KVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
.  |...|  | .|  .. ||.. . . ... | |     | | |..|||..||| ||||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase kin-1.AA S_TKc 52-306 37 4.3e-108 366.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISG--GEMFSHLRRIGR---
.. ....| |.||.|....|| .| ..|.||..          ||...| .||.  . |..|..  .| | ..||||.|...|  |..|..... ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK-AVDWWALGVLIYEMAA
   |.| | |||..||..| ||.||.  |.|||||||.|.|.   .||.|||.|...     |.||||.|.|||..   ||.| ..|||..|...|||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGV--ADIKNHKWF
|||||   |. ....||.          | |.||.....||.| .||..  .      |||.| ||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase kin-1.AA p70 52-306 36 1.9e-98 333.36 In-house 1-299 (299) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-299/299
Sequence Identity: 36% (109 aa)

FDRIKTLGTGSFGRVMLVKHKQ---SGNYYAMKILDKQKVVK-LKQVEHTL-------------------------NEKRILQAIDFPFLVNMTFSFKDN
| ..| || | .| |..|.  .   .| .|||| | | |.|   |  .||                           |  || ..  ||..   ..|..|
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV--KGRT-----------WTLCG
. || .||...||| | || | | . |   .||.. |..| |.||... ||||||||| . .. | .. ||||  |    .|             .|.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
|.|| ||||.. .|.|.|||||.||.|.| |  | ||| .. . .. .||  ||  .| |   ..| .||.| ||  . |.| |   . .|||. |..|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase kin-1.AA Ciliate-E2 52-306 27 1.4e-96 327.19 In-house 1-365 (365) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-365/365
Sequence Identity: 27% (105 aa)

FDRIKTLGTGSFGRVMLVKH-----------------------KQSGNYYAMKILDKQKVVKLKQVEHTL----------NEKRILQAIDFPFLVNMTFS
.. || .|.|.|| | ..|.                       |. ...|||||. |...  .||..| .          |||.||. ...|....|  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--DNSNLYMVLEFISGGEMFSHLR-------------------RIGRFSEPHSR-------FYAAQIVLAFEYLHSLD-LIYRDLKPENLLIDSTGYL
|.  |..|.|.|.|...||..|....                    |.....   .       ||.|.|.||.|||||    |.||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGFAKRVKG----------------------------------RTWTLCGTPEYLAPEIILSKG---------YNKAVDWWALGVLIYEMAAGYPP
||.|||..|...                                    ..|.||||.|.||||. .|.         |....|.|.|||..|||  |.||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FFADQPIQIYEKIVSGKVKFP------------------SHFSNELKDLLKN----LLQVDLTKRYGNLKNGVADIKNHKWF
|        ...|  .|..||                   . |.| |||.|.    .||.|  ||..    |  .|.||.||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF
Kinase kin-1.AA Pkinase 52-306 32 6.8e-91 313.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTL-NEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGG----EMFSHLR--RI
. .....| ||||.| . .|| .|  .|.||..|..  . |...|.. .| .|.. .. |. | .  .| |....|||.|.  ||    . |....  | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRF--SEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYL----KITDFGFA----KRVKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWAL
|.|  || . .||. ||. . ||.||   |.|||||||.|||..|..    ||.|||.|       .. ..|.||||.|.|||.|. ...| ..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLIYEMAAGYPPFFAD------QPIQIYEKIVSGKVKFPSHFS---------------------NELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWF
|...|||. |.|||  .       ..|....| .....|..  .                      |.||..|..|..| .||..      ..|..|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase kin-1.AA TyrKc 52-293 20 6.2e-14 2.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 52-293
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAI--DFPFLVNMTFSFKDN-------SNLYMVLEFISGGEMFSHLR
   .|.|| | ||.|.. . |      | | | . .      .|  ..| ||.  .  . | .|..     .          |..|.|. ..|   ..||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RIGR-FSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGR-------TWTLC----GTPE-----YLAPEIILSKGYN
. .. .. ..   .. ||    |||||  .| |||   | |... .  ||.||| .. ..                  |.        .||| |  . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWALGVLIYEMAA-GYPPFFA-----DQPIQIYEKIVSG-KVKFPSH--------FSNELKDLLKNLLQVDLTKR------YGNL
 . | |. ||...|.   | .|          .....|.. .|   . | .         . |. .. |   . |  .|      .  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase kin-1.AA Pkinase_Tyr 122-262 27 3.7e-05 18.11 Pfam 80-232 (270) Show / Hide 
Range on Protein: 122-262
Range on HMM: 80-232/270
Sequence Identity: 27% (42 aa)

NSNLYMVLEFISGGEMFSHLRR----IGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV-------KGRTWTLCGT
| ..|.|.|.  .| . ..||.     .... ..   ...||  . |||.|  .| |||   | |.....  ||.||| |. .       . |. .    
N-QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LP

PEYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPP-FFADQPIQIYEKI-VSG
   .||| |  . .. . | |. |||..|.   |  | .    . ..||.|  .|
IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
Kinase kin-1.AA Pkinase_Tyr 52-68 41 0.554931 3.95 Pfam 1-17 (270) Show / Hide 
Range on Protein: 52-68
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

FDRIKTLGTGSFGRVML
   .|.|| |.||.|..
ITFGKKLGEGAFGEVYK