Gene K08H2.5 (Nematode worm)

K08H2.5

Species: Nematode worm
Alias: aSWK273, K08H2.5, CE06163
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: X:11.73, WormBase Physical Map location: X: 13246006-13244837,

Classification

Group: Other
Family: Worm5

Sequence

Name Sequence Type Origin Length Description Download
K08H2.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 244 Kinase domain by global Sugen HMM Fasta, JSON
K08H2.5.AA Protein Genbank 312 None Fasta, JSON

Protein domain

Protein domains of K08H2.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase K08H2.5.AA Worm5 21-279 56 1e-216 656.89 In-house 1-260 (260) Show / Hide 
Range on Protein: 21-279
Range on HMM: 1-260/260
Sequence Identity: 56% (148 aa)

YKIVEVLGSGEYGTAFACVDADSRHSTLALKASNLET-IFCENCFKLERTVLQRISTLGTNEKSRFPTLVDNFVVDSTLGCLVMTKEGDSLGDVCKRNDP
|.|..|||.|||||..||||.|.||..||.||.|.|. |.||||||||..|.|||.|||.||..|||...|||.||||..|.||.||||.|.||..||..
YYIIYVLGEGEYGTIYACVDMDDRHNQLAIKAMNFEHGIQCENCFKLELMVFQRIDTLGNNERNRFPQFCDNFQVDSTYYCFVMHKEGDCLNDVWMRNKN

KKFSPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKFRNRRGNYVKNRPQRDVNFKECGHVSWNVMMGGVPNLKDDF
|.||..||||||.....||||.||.|.||||.||.|..|||.|||..||||||.|.||.|.||||.|.|.|||||||||.|.|.||||..||.|..||||
KRFSRKNVLKIMCCMSHSLQTLHSIGFIHRDCHWQNIMFAKRITPINPCKLIDFGIGKRFKNRRGHYCKDRPQRDVNFKDCRHCSWNVHCGGIPRKKDDF

SSLMFLGLKISGISSLEIGSVSEVRHQKMIFELDPSRFLRSVPWLLKVACVIVDSDAEKF
.|.|.|.|..|||.............|||.|...|..||...||.  |   .   . . |
ESMMYLALRMSGIHCYRYENKEQRFCQKMKFHFNPEQFLMNCPWMTIVFKSMRKQNDDDF
Kinase K08H2.5.AA Worm7 100-225 39 2.4e-22 71.69 In-house 77-200 (263) Show / Hide 
Range on Protein: 100-225
Range on HMM: 77-200/263
Sequence Identity: 39% (50 aa)

CLVMTKEGDSLGDVCKRNDPKKFSPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKFRNRRGNYVKNRPQRDV--NF
|.||  || .| || |||  | ||  ||. |   .|  |  ||  ..||||.|  |||       .    |||.|   .|.   || .   || .   ..
CIVMSEEGQNLRDVVKRNNNKPFSTNNVIRIAWQIGSTLCFIHNKSFIHRDVHSQNVLVTLKNKVCK-MVLIDFGNAVRFKDVNGNEL---PQFNDGYQY

KECGHVSWNVMMGGVPNLKDDFSSLMFL
  | | | ||| |     .||  || .|
HHCVHKSINVMKGNPHTCRDDWISLIYL
Kinase K08H2.5.AA CK1 21-151 21 8.9e-16 51.57 In-house 1-158 (339) Show / Hide 
Range on Protein: 21-151
Range on HMM: 1-158/339
Sequence Identity: 21% (34 aa)

YKIVEVLGSGEYG-TAFAC-----VDADSRH----STLALKASNLETIF-CENCFKLERTVLQRISTLGTN-------EKSRFPT----------LVDNF
.|.|. .|.| .| . . .     .| ..         |.|   .| .      ..|.. ..    . | .       ..  |..          ... .
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMK---VEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHG

VVDSTLGCLVMTKEGDSLGDVCK--RNDPKKFSPTNVLKIMLSVGKSLQTIHSLGYIHRDI
 .|     .|||  | .|.|. |  |.  .||| . .|.|..   ..|. .|. |.|||||
EEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDI
Kinase K08H2.5.AA S_TKc 21-305 13 5.5e-10 -30.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-305
Range on HMM: 1-231/231
Sequence Identity: 13% (43 aa)

YKIVEVLGSGEYGTAFACVDADSRHSTLALKASNLETIFCENCFKLERTVLQRISTLGTNEKSRFPTLVDNFVVDSTLGCLVMTKEGD---SLGDVCKRN
|.|....|.| .|. . |.. .  .   |.|  .       . .. |. .|..             .| | |.   .  ..||   .    .| |. |..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-------EHIRREIQILKK-------HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKR

DPKK----FSPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKFRNRRGNYVKNRPQRDVNFKECG---------HVS
 ...    |..  . ..|  . . |. .||.| ||||.   |.|. .        |..| |. ...                    ||           .
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-----------------TTFCGTPWYMAPEVL-G

WNV--------------MMGGVPNLKDDFSSLMFLGLKISGISSLEIGSVSEVRHQKMIFELDPSRFLRSVPWLLKVACVIVDSDAEKFNYAGVFNAIKQ
..               |. | |    .   .. . .                                                        . . |..
YGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------------------------------------------------SPEAKDFIRK

GFPFDEE-----EIIN-------HSYL
 . .| |     |. .       | ..
CLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase K08H2.5.AA Worm8 102-185 33 2.7e-08 20.01 In-house 76-158 (261) Show / Hide 
Range on Protein: 102-185
Range on HMM: 76-158/261
Sequence Identity: 33% (28 aa)

VMTKEGDSLGDVCKRNDPKKFSPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKFRNRRGN
|| .  | |  .  ||. |.||     .||  . | || ||| | .| ||  .| .            |.|.|.  .|.   ||
VMEQLSDDLINIICRNENKMFSKPTGYQIMWQLVKILQDIHSFGIVHGDIKADNLMVSHSNR-MFMLVLVDFGCSCWFKDHNGN
Kinase K08H2.5.AA TTBKL 107-151 34 4.4e-08 23.45 In-house 83-128 (288) Show / Hide 
Range on Protein: 107-151
Range on HMM: 83-128/288
Sequence Identity: 34% (16 aa)

GDSLGDVCKRNDPKK-FSPTNVLKIMLSVGKSLQTIHSLGYIHRDI
|..|.|. |..  || ||.. .. |.  . ..|. .|. |.||||.
GPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDV
Kinase K08H2.5.AA DMPK 138-157 50 1.3e-07 14.02 In-house 113-132 (270) Show / Hide 
Range on Protein: 138-157
Range on HMM: 113-132/270
Sequence Identity: 50% (10 aa)

LQTIHSLGYIHRDIHWNNVL
. .||..||.||||   |.|
IHSIHQMGYVHRDIKPDNML
Kinase K08H2.5.AA TTBK 101-185 27 1.5e-07 22.83 In-house 73-157 (257) Show / Hide 
Range on Protein: 101-185
Range on HMM: 73-157/257
Sequence Identity: 27% (23 aa)

LVMTKEGDSLGDVCKRNDPKKFSPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKFRNRRGN
.||.  | .| |        .||    |.. . . .|.. |||.|. ||||   |    ..      | ..|.|   .. |  |.
MVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGE
Kinase K08H2.5.AA Ciliate-E2 106-193 25 4.5e-07 20.3 In-house 117-219 (365) Show / Hide 
Range on Protein: 106-193
Range on HMM: 117-219/365
Sequence Identity: 25% (29 aa)

EGDSLGDVCKRN----------DPKKFSPTNVLKIMLSVGK---------------SLQTIHSLG-YIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKF
.| .| | .| |          | |.|.   ...||  . .                |. .|| .  |||||  .|.||         .|.|| |  ||.
QGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKY

RNRRGNYVKNRPQR
 . . |. .  .|.
DDDNQNRTH-KQQC
Kinase K08H2.5.AA Worm9 115-175 37 1e-06 19.12 In-house 94-154 (291) Show / Hide 
Range on Protein: 115-175
Range on HMM: 94-154/291
Sequence Identity: 37% (23 aa)

KRNDPKKFSPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGV
|| | .. |. |. || .     |  ||  | ||.||   ||.|           |||||.
KRCDDRRISDRNIIKIAFRLVNILEHIHQKGVIHQDIKTDNVMFRSRVQNKVNIVLIDYGI
Kinase K08H2.5.AA STE 136-175 39 0.000164 11.99 In-house 162-193 (359) Show / Hide 
Range on Protein: 136-175
Range on HMM: 162-193/359
Sequence Identity: 39% (16 aa)

KS-LQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGV
|  |. .||...|||||   |.|.         .||.| ||
KGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGV
Kinase K08H2.5.AA Pkinase 120-186 25 0.000181 16.88 Pfam 101-168 (293) Show / Hide 
Range on Protein: 120-186
Range on HMM: 101-168/293
Sequence Identity: 25% (18 aa)

KKF--SPTNVLKIMLSVGKSLQTIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKF-RNRRGNY
..|  |.  . ..|. . . |. .|| | ||||.   |.|. .. ..... |..| |. |.|   . . .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-M
Kinase K08H2.5.AA Pkinase 21-75 18 0.000309 16.06 Pfam 1-58 (293) Show / Hide 
Range on Protein: 21-75
Range on HMM: 1-58/293
Sequence Identity: 18% (11 aa)

YKIVEVLGSGEYGTAFACVDADSRHSTLALKASNLETIFCENC--FKL--ERTVLQRIS
|.|....||| .|. . |.. .... . |.|  ..... .. .    .  |  ...|..
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN
Kinase K08H2.5.AA Worm9 21-44 33 0.001026 8.79 In-house 1-24 (291) Show / Hide 
Range on Protein: 21-44
Range on HMM: 1-24/291
Sequence Identity: 33% (8 aa)

YKIVEVLGSGEYGTAFACVDADSR
||| .  | | ||  .. .| . .
YKIRFDIGKGRYGHIYSVLDQQDQ
Kinase K08H2.5.AA STE 21-42 22 0.001073 9.07 In-house 1-22 (359) Show / Hide 
Range on Protein: 21-42
Range on HMM: 1-22/359
Sequence Identity: 22% (5 aa)

YKIVEVLGSGEYGTAFACVDAD
....|..|.| .|| . ... .
WEGIEKIGKGAFGTVYKAMNHK
Kinase K08H2.5.AA Ciliate-E2 21-33 38 0.014721 4.58 In-house 1-13 (365) Show / Hide 
Range on Protein: 21-33
Range on HMM: 1-13/365
Sequence Identity: 38% (5 aa)

YKIVEVLGSGEYG
||.....|.| .|
YKFIKKIGQGNFG
Kinase K08H2.5.AA TTBKL 21-34 35 0.260161 0.27 In-house 1-14 (288) Show / Hide 
Range on Protein: 21-34
Range on HMM: 1-14/288
Sequence Identity: 35% (5 aa)

YKIVEVLGSGEYGT
..||...|.| .|.
WMIVKMIGEGGFGQ