Gene K08B4.5 (Nematode worm)

K08B4.5

Species: Nematode worm
Alias: aSWK214, K08B4.5, CE18034
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 6089393-6085844, WormBase Genetic Map location: IV:2.98,

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
K08B4.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 220 Kinase domain by global Sugen HMM Fasta, JSON
K08B4.5.AA Protein Genbank 488 None Fasta, JSON

Protein domain

Protein domains of K08B4.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
UCH K08B4.5.AA UCH 112-215 19 2.8e-17 50.46 Pfam 268-403 (403) Show / Hide 
Range on Protein: 112-215
Range on HMM: 268-403/403
Sequence Identity: 19% (29 aa)

KIHDKFEFPFH-IHMDNFLED--------------------------------------ASEDSQQTLHKYNLHAIIVHLG-EDGKGHFMTYRS---IRN
||.|..||||  . |......                                      ..| ..   .||.|.|...| | . . || ..|     . |
KINDRVEFPFEDLDMSPYCNCEPKEKEQPRWDDEKIEKKPKQRNDEDGNMWCMHEEEEQDNERGENPPCKYELYAVVCHYGCSPHGGHYWCYCKKDHNKN

NCDVEGLATQWVKLDDAISTIIQRD-QIASQSFGSGSNEDSSAVLLMF
|.        |.|.||   |... . .. ....|    ...|| .|. 
NK--------WYKFDDDHVTRVTEWEEVLKENGG----DWWSAYMLFY
Kinase K08B4.5.AA Haspin 241-459 23 5.7e-80 271.98 In-house 1-264 (264) Show / Hide 
Range on Protein: 241-459
Range on HMM: 1-264/264
Sequence Identity: 23% (63 aa)

VLKLLGSGDSGDVYAVTWMGTEYTLKLAKSNNSKT-------------KSEQLVEVQNMAKIQKVLPD--APNFPECLEAYFINDIPTEICQKLQSSAKV
. | .|.|..|.|..|||.|.|...|. . ..|..             ..|.| |...| |..|. ..  .||||...........|...|.||......
NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH

RVDN-----------------YCRIVEYESKTLTPVRRRPNPPFTQ------------SGKKENGFWHEDLHKGNILLA-VTDKDFIKYRVDKKLIKLRT
....                 ...|.||....|...|...|.....             .|.|..|||.|||.||.|.. .|.|....|..|.| ||...
YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS

NGLMETSLTSCSYRIMKELSKKLFEAKTIEEFWNYQDLLESVIVIDKPNNINHIGILQDISNLR
.|.|.| .. |..|..|. .|.....|..|....... .......|...|..|........|..
HGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK
Kinase K08B4.5.AA Worm5 361-377 47 0.000168 9.54 In-house 126-142 (260) Show / Hide 
Range on Protein: 361-377
Range on HMM: 126-142/260
Sequence Identity: 47% (8 aa)

GFWHEDLHKGNILLAVT
|| | |.| .||. |..
GFIHRDCHWQNIMFAKR
Kinase K08B4.5.AA TKL-Unique 241-266 30 0.000169 11.99 In-house 1-26 (290) Show / Hide 
Range on Protein: 241-266
Range on HMM: 1-26/290
Sequence Identity: 30% (8 aa)

VLKLLGSGDSGDVYAVTWMGTEYTLK
.....|.| .| || ..| |.....|
FWNKIGEGGYGQVYKGKWRGYPVAIK
Kinase K08B4.5.AA MLK 239-262 29 0.000172 11.64 In-house 1-24 (291) Show / Hide 
Range on Protein: 239-262
Range on HMM: 1-24/291
Sequence Identity: 29% (7 aa)

IKVLKLLGSGDSGDVYAVTWMGTE
|.... .||| .|.|.  .| ...
IQFHEWIGSGSFGKVWKGRWRNKD
Kinase K08B4.5.AA TKL 245-290 18 0.000309 11.17 In-house 1-83 (364) Show / Hide 
Range on Protein: 245-290
Range on HMM: 1-83/364
Sequence Identity: 18% (15 aa)

LGSGDSGDVYAVTWMG----------TEYTLKLAKSNN---------------------------SKTKSEQLVEVQNMAKIQ
.||| .| ||  .|.|          ..   |  ||.|                           |. . .  .|.  | ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLR
Kinase K08B4.5.AA MLK 239-271 30 0.000451 9.1 In-house 1-33 (280) Show / Hide 
Range on Protein: 239-271
Range on HMM: 1-33/280
Sequence Identity: 30% (10 aa)

IKVLKLLGSGDSGDVYAVTWMGTEYTLKLAKSN
.|. ...|.|  | ||  .| | |  .| ....
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQD
Kinase K08B4.5.AA TK 239-298 18 0.00047 8.64 In-house 1-104 (486) Show / Hide 
Range on Protein: 239-298
Range on HMM: 1-104/486
Sequence Identity: 18% (19 aa)

IKVLKLLGSGDSG---DVYAVTWMG---------------------------TEYTLKLAKSNNSKTKSEQLV--------------EVQNMAKIQKVLP
|...| ||.|  |   .||  .| |                           |.   |  |. .. .. |..               |.. |.. .  | 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DAPN
. ||
HHPN
Kinase K08B4.5.AA CK1 239-290 24 0.000696 9.53 In-house 1-65 (339) Show / Hide 
Range on Protein: 239-290
Range on HMM: 1-65/339
Sequence Identity: 24% (16 aa)

IKVLKLLGSGDSG-DVYAV-----TWMGT-------EYTLKLAKSNNSKTKSEQLVEVQNMAKIQ
 || |..|.|  | ..| |     . | .       || .|. . .. . ..  ..|.| ..| |
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQ
Kinase K08B4.5.AA Worm5 240-256 35 0.021101 3.14 In-house 2-18 (260) Show / Hide 
Range on Protein: 240-256
Range on HMM: 2-18/260
Sequence Identity: 35% (6 aa)

KVLKLLGSGDSGDVYAV
..  .||.|  | .||.
YIIYVLGEGEYGTIYAC