Gene K08B12.5 (Nematode worm)
K08B12.5
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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K08B12.5.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 269 | Kinase domain by global Sugen HMM | Fasta, JSON |
K08B12.5.AA | Protein | Genbank | 1548 | None | Fasta, JSON |
Protein domains of K08B12.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | K08B12.5.AA | DMPK | 83-351 | 67 | 5.1e-292 | 733.32 | In-house | 1-270 (270) | Show / Hide |
Range on Protein: 83-351 Range on HMM: 1-270/270 Sequence Identity: 67% (184 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPES ||.|||||.|.||||.|||.. ....||||..|||||.||||||||.||||..|.|..||||.||||||||..||.||.|..|||.|||.|.. |.|||. FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED MAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDG-RGRYGKECDWWSLGICMYEM ||.||.|||||||.|.|..||||||.||||.|||..|||.|||||||... .|| | |.||||||||||||.|.||||. .||||.||||||.|.||||| MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNRDGMVRSKVAVGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEM LYGTTPFYSERLVDTYGKIMSH-QDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFF |||.|||| ..||.||||||.| ...|.||||. |.|||||||||.||.|....|.||||. ||. |||| LYGETPFYADSLVETYGKIMNHCKNHLSFPDDPK-WDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF |
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Kinase | K08B12.5.AA | GEK | 83-351 | 78 | 5.4e-206 | 690.63 | In-house | 1-269 (269) | Show / Hide |
Range on Protein: 83-351 Range on HMM: 1-269/269 Sequence Identity: 78% (212 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPES ||.|||||.|||||||||.|......|||||||||||.||||||||||||||||.||||||||||||||||..||.|||||.|||.||||||| |..||. FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED MAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEML ||.|||||||.||||.|.|.|||||.|||||||||.|||||||||||||. .||.|.||||||||||||||||.|||||.||||.||||||||.|||||| MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNKDGMVQSNVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEML YGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFF ||.||||.|.||.||||||.|.|...||..|.||.|||||||||||||||...|.||||..||. |||| YGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF |
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Kinase | K08B12.5.AA | AGC | 83-351 | 30 | 1.3e-167 | 437.48 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 83-351 Range on HMM: 1-395/395 Sequence Identity: 30% (124 aa) FEVLKVIGKGAFGEVAVVRMR------GVGEIYAMKILNKWE--------MVKRAETAC-------FREERDVLVYGD----------RRWITN-LHYAF ||.|||||||.||.| ||.. . |..||||.|.|.. ||... |.. ..|||..|. . .|.. |||.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDEKN--LYFVMDY--------YIGGDMLTLLSKFVD----HIPESMAKFYIAE-------MVLAIDSLHR-LGYVHRD-VKPDNVLLDMQGHIRLADFG ||... |||||.| |.||.. ..|... . . .|..|.||.|| .|||...||. .|..||| .||.|.||| .|||.|.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG SCLRILADG-------------------------------------------------SVASNVAVG--TPDYISPEILRAMEDGRGRYGKECDWWS--L .| .. || . . .| ||.|..|||| |||.||||| | LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---------YGKACDWWSFGL GICMYEMLYGTTPFYSERLV----------DTYGKIMSHQ----DMLDFP-----DDEIDWVVSEEAKDLIRQLIC-SSDVRFGRN-------GLSDFQL |..|||||.| .|||.. . ... |||... . . || . . | .|.||||||..|.| . | | . | .. . GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN HPFF ||.| HPWF |
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Kinase | K08B12.5.AA | ROCK | 83-351 | 52 | 3.8e-129 | 435.36 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 83-351 Range on HMM: 1-263/263 Sequence Identity: 52% (141 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPES |...||||.|||||| .|| . ..||||.|.| ||.||.. | | ||||.. . || |||||||.. || |||| |||. |.|.. .|| FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNY--DVPEK MAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEML |.|| .|.|||.|..| .|..||||||||.||| .||..||||| |... ..| | .. |||||||||||.|.. . |.||.|||||| |. .|||| WARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNKNGMVRCDTAVGTPDYISPEVLKSQG-QDGEYGRECDWWSVGVFIYEML YGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFF | |||| . || ||.||| |.. | |||| .|..|||||.. . ..| ||||. | . |.|| VGDTPFYADSLVGTYSKIMDHKNSLKFPDDV---EISKQAKDLICKFLTDREQRLGRNGVDDIKQHKFF |
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Kinase | K08B12.5.AA | CRIK | 83-351 | 44 | 3.4e-118 | 378.49 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 83-351 Range on HMM: 1-272/272 Sequence Identity: 44% (124 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPES ||| .||.| ||.| ||| . . |||||.. | .. . . . | ||||.. |...| |||||. ||| .| | ||| | |.. . | |. FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN MAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMED---GRGRYGKECDWWSLGICMY ||.|| || ..|. ||| ||||||.||.|.|.| ||| |||||| . .. | | ||||||. ||.| | ..| || .|||||.|| | MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAKMNRNNHVNSKMPVGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAY EMLYGTTPFYSERLVDTYGKIMS------HQDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFF || .|.||| . || .||. | .| |||| || .. |||..|.| | . .| |||| EMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDP---KVSPNYRDLIQSLLCNQSKRLKYEQL---CCHPFF |
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Kinase | K08B12.5.AA | S_TKc | 83-351 | 32 | 2.9e-85 | 290.51 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 83-351 Range on HMM: 1-231/231 Sequence Identity: 32% (92 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIG--GDMLTLLSKFVDH-- .|.|..|||||||.| .| .. |.|.|.||.. .| |...| . .| .|...||| ..||.||.| | ||..... | | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---IPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGK-ECDWWSL .|| .|.||......|.. .|..| .|||.||.|.||| || ..|||.. .. . .|||.|..||.| ||| .|||||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--------GYGKCKCDWWSC GICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLIC-SSDVRFGRNGLSD----FQLHPFF |...||||.| .||. . .. ||. |.||||.||.. . . | . . .||.| GCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | K08B12.5.AA | NDR | 83-238 | 51 | 1.6e-84 | 260.51 | In-house | 1-155 (350) | Show / Hide |
Range on Protein: 83-238 Range on HMM: 1-155/350 Sequence Identity: 51% (83 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGD--RRWITNLHYAFQDEKNLYFVMDYYIGGDMLT---LLSKFVD ||..|.||||||||| .||.. |.||||||..| ||... ..| | |||... | .|.. | |.|||...||.||.| .|||| | ||.|. | FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKM-D HIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSV .|..|.|||||||.||.|.|..||.|||.|||| |.| .||| | ||| |..|.. IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG-----LCTGGM |
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Kinase | K08B12.5.AA | RSK | 86-351 | 37 | 2.5e-77 | 263.22 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 86-351 Range on HMM: 1-278/278 Sequence Identity: 37% (106 aa) LKVIGKGAFGEVAVVRMR---GVGEIYAMKILNKWEMVKRAE-TACFREERDVLVYGD-RRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDH-- ||| |.|..|.| ..| | |||||.|.| ..|.|. |. ..||..| | .||||||.|. || .|.| ||...| |.| . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC IPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDM---QGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLG . |. |.||.|| |||.. || .| .||| ||.|.|.| .|||.| ||| | .| . . ..| .|. ||.|. . ..| ..| ||||||| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLG ICMYEMLYGTTPFYS---ERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQLIC-SSDVRFG--RNGLSDFQLHPFF . ||||| | .||.. . .. .|.. . |..| .. .|.|||||||.. . | | ...... . ||.| VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQ---YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | K08B12.5.AA | Akt | 83-329 | 39 | 1.2e-71 | 228.28 | In-house | 1-239 (264) | Show / Hide |
Range on Protein: 83-329 Range on HMM: 1-239/264 Sequence Identity: 39% (100 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIY-AMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPE |..|||.|||.|| | |. ...| |||.| | ... . . || .|. . |.||||.||....||||||| ||. ..|.. ..| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQR-KRRFSE SMAKFYIAEMVLAIDSLHRLGYVHRD-VKPDNVLLDMQGHIRLADFGSCLRI-LADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWS-LGICM . |.||.||..|||. || . . || || |.|.| .|||.|.||| | .. . |. .. . ||| |..|||| .| | ..| .|||. ||. | DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTF-CGTPEYLAPEIL----NGNG-HTKAVDWWGSLGCVM YEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEEAKDLIRQL |||..| |||.. . ||.. . . ||| ..| |.||||..| YEMMCGRPPFYNQDHHQMFKKIKNQP--VKFPDK---DWISPECKDLISGL |
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Kinase | K08B12.5.AA | MAST | 83-227 | 41 | 6.9e-57 | 172.02 | In-house | 1-147 (337) | Show / Hide |
Range on Protein: 83-227 Range on HMM: 1-147/337 Sequence Identity: 41% (61 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQD--EKNLYFVMDYYIGGDMLTLLSKFVDHIP || .|.|.|||.| | |. . ....|||..|. . .. . ||..|.. . .. .. |.|| .| |..||.| .||| .||. . | FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP ESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFG |.|||.|||| ||... || | ||||.||||.|.| ||| |.||| EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG |
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Kinase | K08B12.5.AA | MAST | 83-227 | 41 | 4.8e-56 | 179.01 | In-house | 1-144 (334) | Show / Hide |
Range on Protein: 83-227 Range on HMM: 1-144/334 Sequence Identity: 41% (60 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPES || |.|.|||.| | |. . ....|||...| .| .. . . ||..| . . .. .. |.|| ...|..||.| .||| .||. . .|. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG-YFDEW MAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFG |||.||||.||... ||. | ||||.||||.|.| ||| |.||| MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFG |
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Kinase | K08B12.5.AA | Pkinase | 83-331 | 28 | 7e-53 | 186.8 | Pfam | 1-275 (293) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-275/293 Sequence Identity: 28% (80 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFR-EERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGG----DMLTLLS-KFV ......||.|.||.| . .| |.|.|.||..| . . . . .| | .. . | |...|.|....|.||.| || | ...| . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH DHI--PESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHI----RLADFGSCLRI-LADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKEC . .| .|||. ... ... .|. | .|||.||.|.|.| .||| ...|||.. . . .| .. .|||.|..||..| |. ||... GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIR----GGQYYGPKV DWWSLGICMYEMLYGTTPFYSE------RLVDTYGKIMSHQDMLDFPDD---------------EIDWVVSEEAKDLIRQLIC |.||.|. .|||| | .||... . . .||. . . |.| . . .|||.||.|. ..| DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLC |
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Kinase | K08B12.5.AA | NDR | 243-351 | 42 | 3.3e-44 | 133.83 | In-house | 241-350 (350) | Show / Hide |
Range on Protein: 243-351 Range on HMM: 241-350/350 Sequence Identity: 42% (49 aa) AVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFP--DDEIDWVVSEEAKDLIRQLIC-SSDVRFGR .||||||. ||.. . | |...||||||| ||||| | .||.|. .|. |||. . ..| | ... . .|.||.||||.|.| | | |. TVGTPDYMAPEVFQQ-KTG---YNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGS NG--LSDFQLHPFF .| ... |||| HGKGVDEIKSHPFF |
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Kinase | K08B12.5.AA | MAST | 244-351 | 39 | 1.1e-32 | 96.73 | In-house | 229-337 (337) | Show / Hide |
Range on Protein: 244-351 Range on HMM: 229-337/337 Sequence Identity: 39% (45 aa) VGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVD-TYGKIMSHQDMLDFPDD---EIDWVVSEEAKDLIRQLICSS-DVRFG .||||||.||.. |.| ||| ||||.|| ||| | |..|| . . ..| .|.... .|.. . |. .|.||.|||..| .| | CGTPDYIAPEVIL----GQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLG RNGLSDFQLHPFF || . |||| ANGADEIKQHPFF |
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Kinase | K08B12.5.AA | MAST | 244-351 | 37 | 9.8e-28 | 86.22 | In-house | 225-334 (334) | Show / Hide |
Range on Protein: 244-351 Range on HMM: 225-334/334 Sequence Identity: 37% (43 aa) VGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQ-DMLDFPDD---EIDWVVSEEAKDLIRQLICS-SDVRFG .||||||.||.. |.| .|| ||||.||.||| | |..|| . ....| .. .|.. . |. |.||.|||..| .| | CGTPDYIAPEVIL----GQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLG RN-GLSDFQLHPFF | | . . |||| ANNGADEVKQHPFF |
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Kinase | K08B12.5.AA | S_TK_X | 352-416 | 28 | 6.8e-16 | 60.05 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 352-416 Range on HMM: 1-79/79 Sequence Identity: 28% (23 aa) EGIDWNTIR----DSNPPYVPEVS----SPEDTSNFD-VDVCEDDFTPCETQPPRVLAAFTGNH--------LPFVGFSYTH ||||.... ||..|... ||.|||||| |.. .| ....| . .. .|| ||.| . RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | K08B12.5.AA | Pkinase_C | 369-418 | 36 | 3.4e-10 | 39.15 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 369-418 Range on HMM: 1-46/46 Sequence Identity: 36% (19 aa) EVSSPEDTSNFD-VDVCEDDF-TPCETQPPRVLAAFTGNHLPFVGFSYTHGS .|.||.|||||| . .|.. || | . |...||.||.|.. . QVKSPTDTSNFDPEFTDEPPMDTP-----PDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | K08B12.5.AA | TyrKc | 83-342 | 18 | 1.4e-09 | -67.95 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 83-342 Range on HMM: 1-280/280 Sequence Identity: 18% (56 aa) FEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYG--DRRWITNLHYAFQDE-------KNLYFVMDYYIGGDMLTLLS . .|..| |||||| ... . | | |.. . |..| .. . | .|. . .. . |. || | .|| . | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILAD---GSVASNVAV-----GTPD-----YISPEILRAMED | .... . . . ||. ...||| |.|.. ..... .||| . | | | ... . . |. . .|| . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECI----- GRGRYGKECDWWSLGICMYEML-YGTTPFYS-----ERLVDTYGKIMSHQDMLDFPDDEIDWV----VSEEAKDLIRQLICS--------SDVRFGRNGL |.. . | || |.||.|.. || .| . . . .... | |.|. . ..| ....| |.. . . NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF |
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TMF_DNA_bd | K08B12.5.AA | TMF_DNA_bd | 524-556 | 26 | 1.027802 | 5.58 | Pfam | 100-133 (75) | Show / Hide |
Range on Protein: 524-556 Range on HMM: 100-133/75 Sequence Identity: 26% (9 aa) VAESEKKLKELK-ERNKQLVMEKSEIQRELDNIN ..|.||...||| .. .|..| .. ...|.. . NKELEKQISELKHKKIEKLEKEIENLEQRLKRAE |
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TMF_DNA_bd | K08B12.5.AA | TMF_DNA_bd | 593-619 | 28 | 5.738966 | 2.91 | Pfam | 48-75 (75) | Show / Hide |
Range on Protein: 593-619 Range on HMM: 48-75/75 Sequence Identity: 28% (8 aa) SVKRLQ-DEAEKAKKQVADFEEKLKEIE ....|. .. ||. |.... |..||. | QISELKHKKIEKLEKEIENLEQRLKRAE |
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TMF_DNA_bd | K08B12.5.AA | TMF_DNA_bd | 646-697 | 30 | 0.119527 | 8.92 | Pfam | 24-75 (75) | Show / Hide |
Range on Protein: 646-697 Range on HMM: 24-75/75 Sequence Identity: 30% (16 aa) LSEEVVAAKNTIASLQATNEERETEIKKLK-QRMDEERASHTAQSEQEMKQLE || . ||| .|...|.| |..|..|| ..... ... .. ||..|. | LSKQELKHNNTIKKLRKKNKELEKQISELKHKKIEKLEKEI-ENLEQRLKRAE |
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DMPK_coil | K08B12.5.AA | DMPK_coil | 664-684 | 42 | 5.113639 | 2.63 | Pfam | 41-61 (61) | Show / Hide |
Range on Protein: 664-684 Range on HMM: 41-61/61 Sequence Identity: 42% (9 aa) NEERETEIKKLKQRMDEERAS | | | |...|| .| . || NRELEQEMEQLKKEMEMLRAR |
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DMPK_coil | K08B12.5.AA | DMPK_coil | 810-861 | 32 | 0.001167 | 15.11 | Pfam | 1-52 (61) | Show / Hide |
Range on Protein: 810-861 Range on HMM: 1-52/61 Sequence Identity: 32% (17 aa) DLQRQLQAEIDAKLKLKAELKNSQEQYLTSAARLDDTEKRMASLMREVAMLK .|| | ||| || .. ||. .. . .| ..||. | |...|| ELQSALEAEIRAKQSIHEELNKVKAANIQFECKLQEAEKKNRELEQEMEQLK |
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C1 | K08B12.5.AA | C1 | 956-1005 | 29 | 5.4e-17 | 63.69 | SMART | 1-61 (61) | Show / Hide |
Range on Protein: 956-1005 Range on HMM: 1-61/61 Sequence Identity: 29% (18 aa) HNFERMKIKTPTKCGHCTSILIGLDRQ-----GLFCQSCQYACHVSCAERVSQ-------SC |.... .. .||.| || . ..|...| |..|. |.|.|| .|...|.| .| HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC |
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C1_1 | K08B12.5.AA | C1_1 | 956-1008 | 36 | 1.5e-14 | 57.12 | Pfam | 1-55 (55) | Show / Hide |
Range on Protein: 956-1008 Range on HMM: 1-55/55 Sequence Identity: 36% (20 aa) HNFERM-KIKTPTKCGHCTSILIG-LDRQGLFCQSCQYACHVSCAERVSQSCPVP |.... | ||.| || ... | | .||. || |.| || |...|. |. HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN |
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CNH | K08B12.5.AA | CNH | 1138-1450 | 27 | 1e-123 | 418.22 | SMART | 1-375 (375) | Show / Hide |
Range on Protein: 1138-1450 Range on HMM: 1-375/375 Sequence Identity: 27% (105 aa) RVAQCCAIIDRS----KIVIGFSDHGLYCIEISRQLLIP--VGGEKENKQRCVETVEYDEAEQLLMMIVG----PAKDRHVRI----------------V .....|..|... |.......||.||..|..|.... ...|.....|||......|....||||.| ......|.. . CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQDHM PSAALDGRDLKW-IKVNDTKG-CHLLAVGTNNPGGRAGFFAVAFKKSVTIF-QIDRSEKRHKKWKD--------LAMPGTPQSIAIFNGRLYVGFSHSFR ....|..|...| .|..|||| ||...|..|.......|...|...||.|. |..........||. ..|........||.....|.|.|... CNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDSF --SWSLVGVDSSPVGSGDASGAVLQHI------------SLVNMEDTSLQFLNQQTSY-----EAKLIVNVPGSP----DEYLLVFNMIGLYVNEMG--- .|...|.|. ||| |.......||. |.|||.|.||.|.|||||. ... ...|..|. |.|||.....|..||..| ERPWICIGCDK-PVG-GMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEW RRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLAEW-VQTINLRSAKPLSGDGILSTCLCNDSPIFVLLQN ||.| |.........|||||.||...|..|...|.... .|| .|.|. |..........|.||.|.|..||...|. RRWRNPILHWEFMPEYFAYHYPYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP |
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CNH | K08B12.5.AA | CNH | 1142-1432 | 19 | 7.6e-44 | 156.78 | Pfam | 1-336 (336) | Show / Hide |
Range on Protein: 1142-1432 Range on HMM: 1-336/336 Sequence Identity: 19% (70 aa) CCAIIDRSKIVIGFSDHGLYCIEI--SRQLLIPVGGEKENKQRCVETVEYDEAEQLLMMIVGPAK-D--RHVRIVPSAALDGRDLKW-I----------- .|..... .. .| | ||| ..| .|. . ... .. .. | .. |....|.||. . | .|.. | .||.....| . VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSR-RVTQIYVIEEFNILIMIS---GCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHR -------------KVNDTKGCHLLAVGTNNPGGRAGFFAVAFKK-----SVTIFQIDRSEKRH-------------KKWKD-LAMP----GTPQSIAIF- |. |||.||. .. ..|. . . ..| |. .. ...... |.. .| .. .. | ...|.... IERIMPRKFAMWQKLPDTKHCHFFCW-IRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLP --NGRLYVGFSHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDTS--LQFLNQQTSYEAKLIVNVP-GSPDEYLLVFNMIGLYVNEMGR-RSR--L .| ||... | .| | |. .|....|.| ..| .. . .. .. .. . |.||... .. ||| |. ||| QEKPKLCVGCQKGFHIVNLDGT--------------GQPWWLHDPADHSVQQDFMARRENCKPICMHRINDD-E-EFLLCYDECCVYVNKQGWPRSRKHD PEVMFPTQAKYFAYHEPYLCVFSENEVDIFNVTLA-EW---VQTINLRSAKPLSGDG |.|.. ...||...||| .|..| ..|..| || ||.|.......| .. WEIMWEGMPQSFACCYPYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS |
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PBD | K08B12.5.AA | PBD | 1500-1538 | 31 | 2.1e-10 | 41.8 | SMART | 1-38 (38) | Show / Hide |
Range on Protein: 1500-1538 Range on HMM: 1-38/38 Sequence Identity: 31% (13 aa) ISTPS-DFMHIVHMG-PAPVMELQQNFIDLQSNHSHTSSDK ||||. .|.||||.| . . ...| .|.....| . . ISTPTGNFKHIVHVGPWDG---QTGEFTGLPHQWQHLLKHC |