Gene H25P06.2 (Nematode worm)
H25P06.2
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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H25P06.2.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 340 | Kinase domain by global Sugen HMM | Fasta, JSON |
H25P06.2.AA | Protein | Genbank | 489 | None | Fasta, JSON |
Protein domains of H25P06.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | H25P06.2.AA | CDK9 | 85-424 | 75 | 9.40000000001e-297 | 992.12 | In-house | 1-340 (340) | Show / Hide |
Range on Protein: 85-424 Range on HMM: 1-340/340 Sequence Identity: 75% (255 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMAL ||||.|||||||||||||||||||||||||.|...||||.||.||||||||||||||||.|||..|||.|...|||.|..|.|.....|||||||||... YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF CAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGD |.|||||||||.....||.|||.||.|||.||...||.||||||||||||||.||||||||||||||.|.|..|.|..|||||||||||||||||||||| CEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGD RQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGK |.||..||.|||||||||||||.|||||.|||.||||||.|||||..||||||.||.||..|||||||.||.|..|.....|||.||||||||||||||| RNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFGK NVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF ||||||||||..|.||...||.|||.||..||||.|..|| NVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF |
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Kinase | H25P06.2.AA | CDK | 85-424 | 36 | 3.6e-150 | 483.76 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 85-424 Range on HMM: 1-284/284 Sequence Identity: 36% (131 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTG-----RMVALKKILMEN-----EKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKD ||||.|||.||.| .|.|||.|.|| ..|||||| ||| |||||||||.||...| .| |||| |..|| |.. ... || YEKLEKIGEGTYG-----------VVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KD R--ATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGI-----LKLADFGLARPFVQREN-GAGPRPLY . ..|.|. . |||..... ||..|. |..||. .|. .|.|||.| .| ||...|. ||.||||||| | ... . .|. | KHENKLYMVFEYMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTY TNRVVTLWYRPPELLLGDRQYG--TKIDVWGAGCIMAEMWT---RQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRI |..|||||||.||||||...|. | ||.|..|||.|||.| |.|...||.|. || .|. .||. . |.||... .|.. THEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------ LPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF .||. .|. ||.|| ....| .. .| -------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF |
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Kinase | H25P06.2.AA | CMGC | 85-424 | 23 | 2.4e-119 | 394.08 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 85-424 Range on HMM: 1-513/513 Sequence Identity: 23% (124 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARC--------------KNTGRMVALKKIL---MEN------EKEGFPITALREVKMLEQLK---------- ||...|||.||.| .|.|.|. ..|...||.||| .|. ||.||||.||||.|.|..|. YEIIKKIGEGTYG-----------VVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRR -------HPNITDLIEVCSAKSTGTTGSKDR-------ATFYLVMALCAHDLAGLLSNPK--------IRMSLVH------------IKTMM------KH |.|| |.... | . .....|. .|||. .. |||.... | . . .| | || .| . DDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQ LMSGLN--KLHRSK--ILHRDMKAANVLISKD--------------------GILKLADFGLARPFVQREN----------------GAGPRPLYTNRVV . ||. .|. . |.|||.| .|.||... |.||..|||||| . .... . .|. ||..|| ILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVV TLWYRPPELLLGD---------RQYGTKIDVWGAGCIMAEMWTR--------QPIMQGDTE-----------QKQLQLISGLCGSIN------------- |.|||.||.|||. ..|.|.||.|..|||.|||.|. .|. .|..| . ||..| ..|... TRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFC --KDVWPNCVNMPLWSA-------------MS------SEPNSALPQGKYRILPNKMKNLMK-----------------------FDAPDSKTDPFGKNV .. |||....| . .| ..| .|. ... . |..... . |. . . KHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFN----------H-Q KQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF . .. |..|..||. .| .|||||.| ..| . .| -FKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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Kinase | H25P06.2.AA | CRK7 | 85-346 | 40 | 1.3e-110 | 373.8 | In-house | 1-289 (343) | Show / Hide |
Range on Protein: 85-346 Range on HMM: 1-289/343 Sequence Identity: 40% (122 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENE---KEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLV ||... || ||.|| | ||..|.|| ||||||. |.|| |||||||| ||.|.| ||.|.|| | |. | |....||.| YEMIMQIGEGTYGQ-----------VYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMV MALCAHDLAGLLSNPKIR-MSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPEL |||.||| .. . |. ..| .|| |. |.. .|. ..|||| | .|.|. |..|.|||||||.. | |. |||||.||||||||| FEYMDHDLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEK----RRPYTNRVITLWYRPPEL LLGDRQY--------------------------------------GTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPL |||. .| |. ||.|. |||..| |..|| || | .|| .|. .||| | ..||. .|. LLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPW WSAM | .| WNTM |
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Kinase | H25P06.2.AA | CDC2 | 85-424 | 34 | 2.1e-85 | 262.37 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 85-424 Range on HMM: 1-301/301 Sequence Identity: 34% (120 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEG--FPITALREVKMLEQLK-HPNITDLIEVCSAKSTGTTGSKDRATFYLV |.|..||| ||.| .|.|.. . |...|||||| |.| || .| ||.|| | || ||||. | .| |.| YQKIEKIGEGTYG-----------VVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----------NKLYMV MALCAHDLAGLLS--NPK-IRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYT--NRVVTLWYR . .|| .. .|| |.. .| |. . .|.. .|. .|.||| | | ||.|.| .|.||||||| | | || ||||||| FEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGI------PIRTYTTEHEVVTLWYR PPELLLGDRQYGTKIDVWGAGCIMAEM---WTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFD .||.|||...| | .|.| |||.||| |. |. .|| | || | |. | . ||.. ..| . . . . .. .|.||..|. APEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLS---KICPNNQKK----- APDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF |. | .|.... ||. .|..|| || ...|| . .| -------------KNQ-SCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF |
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Kinase | H25P06.2.AA | CDK7 | 85-341 | 38 | 3.9e-80 | 213.0 | In-house | 1-234 (288) | Show / Hide |
Range on Protein: 85-341 Range on HMM: 1-234/288 Sequence Identity: 38% (100 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKIL----MENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYL |||. .|| |.|. |.||. ..||. || ||| . | | ||.||.|.| ..|.|. .|| . .|| .| YEKIKHIGEGQFAT-----------VYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKS----------NIQL VMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPEL |. . || .| . ||| |. . || .|| |||||.| | |....|.||.||||||| . |. | || ||| ||| ||| VFDFMDWDLEVVIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFY-----GS-PNRIYTHQVVTRWYRAPEL LLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMP | | |.||| .|.| |||.|| | |.. || . ||. | | . ||| |. LFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMM |
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Kinase | H25P06.2.AA | S_TKc | 85-424 | 23 | 1.5e-78 | 268.21 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 85-424 Range on HMM: 1-231/231 Sequence Identity: 23% (83 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMAL ||.|.|||.|.||.| ..|. . ||| ||.|.| ....||...|.. .|||| |..|. .|.|| . YEILRKIGKGAFGKVYKCRHKK-----------TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEY CAH---DLAGLLSNPKIR-----MSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYR | . || .. . . . .. |.. .|. . ..|. .|. .|.||| | .|.|... .|..|||||| . | ..|.||. CDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYM PPELLLGDRQYGT-KIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAP .||.| .||. |.|.| |||..|| ...| . ..|. ...| APEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------------------------------------------- DSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAED-------DIWF ...|..... .| ||.|||| || . || ------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | H25P06.2.AA | PITSLRE | 85-346 | 39 | 1.6e-75 | 257.23 | In-house | 1-243 (295) | Show / Hide |
Range on Protein: 85-346 Range on HMM: 1-243/295 Sequence Identity: 39% (106 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILME--NEKEGFPITALREVK-MLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLV ...||.|. ||.| .|..|. | |.. ||||.. || ||||||||.|||.. | |.|||| . |. |... | |.| FQCLNRIHEGTYG-----------VVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIV----MGSNMDK----IYMV MALCAHDLAGLLSNPK---IRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPP | |||..|. | | . .. ||..| | .| .| .|.||| | .| |.| ||||..|||||| . . . || ||||||| | MEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP------IKPYTPCVVTLWYRAP ELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAM ||||| . | | .|.| |||.||. | .|..||. | |.. | . | . || .|.| .| ELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMM |
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Kinase | H25P06.2.AA | CDK5 | 85-343 | 40 | 1.1e-73 | 232.11 | In-house | 1-233 (287) | Show / Hide |
Range on Protein: 85-343 Range on HMM: 1-233/287 Sequence Identity: 40% (105 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMAL |||..||| ||.| |.||| |.|. .||||.. ...| || | ||.||. .| |||.|| |. | . | || YEKMEKIGEGTYGT-----------VYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLT----------LVFEF CAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGD | || . . . |.. || .| |. || | ..||||.| | ||.| |.|||||||||| | | | |. ||||||||| |.| CDQDLKKYMDSCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAF-----GI-PVRCYSHEVVTLWYRPPDVLMGS RQYGTKIDVWGAGCIMAEMW-TRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLW ..| | ||.| .|||.||| . .| | .. || .| . |. . | || ..| . KHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDY |
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Kinase | H25P06.2.AA | CDK-Unclassified | 85-342 | 31 | 3.5e-72 | 236.74 | In-house | 1-271 (324) | Show / Hide |
Range on Protein: 85-342 Range on HMM: 1-271/324 Sequence Identity: 31% (89 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKE----------GFPITALREVKMLEQLKHPNITDLIEVCSAKSTGT---TG |. . |.|.|||| .|.||. .| . || ||| |.| ..||..||.. | ...| || ..... . YRMQCKYGEGTFG-----------CVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYY SKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDG-----ILKLADFGLARPFV------QRENGA . ||.|| .. . | |. . | |. .|. . .|.. || || ||| | .|..|. . .||.||||.|. . .| DNLHPSFYMVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPA GPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPL .| .|. |.| ||| ||||.|...|.| .|.|..|||.||. . || || || |. |... |. . | ||. . ||. DPMQQYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPD |
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Kinase | H25P06.2.AA | Pkinase | 85-424 | 25 | 1e-71 | 249.4 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 85-424 Range on HMM: 1-293/293 Sequence Identity: 25% (90 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALR--EVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVM |... |||.|.||.| .|.. |.||..||.|.| ..||.....|..| |.... |.|||| |.... . |.|| YHIGRKIGSGSFGCV-----------YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----------KDHIYMVM ALCAH-----DLAGLLS-NPKIRM--SLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGIL----KLADFGLARPFVQRENGAGPRPLYTNRV .| . ||. ..| . .. | ..| .|. . .||. .|. .|.|||.| .|.||...| . |..|||||. | . . .| .. EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFC VTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGD----TEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKM .|.||..||...|.. ||.|.|.|..|||..|| ...|. .|. . |.|.| | ... ||. .... . . . . GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------- KNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF . . ........... .|. || |||| ... . || -----------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | H25P06.2.AA | CDK10 | 85-342 | 38 | 4.9e-68 | 232.33 | In-house | 1-233 (285) | Show / Hide |
Range on Protein: 85-342 Range on HMM: 1-233/285 Sequence Identity: 38% (99 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMAL .||||..| ||.| |..|| . .|||||. |. ||.| || .|||...| |..|.|| .| || .. .||| FEKLNRVGEGTYGI-----------VYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHL--------DSIFLVMQY CAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGD | ||| || | . ..| .| .. || ||. ..|||.| .|.|.. .| .|.||||||| . | ..|. | ..|||||| |||||| CEQDLASLLDNMPQPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMY-----GVPVKPM-TPKMVTLWYRAPELLLGC RQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPL |. | ||.| .|||..|. .|.| | | .|...| | |. . .|| ..|. RTQTTAIDMWAVGCILGELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPM |
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Kinase | H25P06.2.AA | Pkinase_Tyr | 85-251 | 28 | 9.9e-17 | 57.28 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 85-251 Range on HMM: 1-159/270 Sequence Identity: 28% (51 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKI---LMENE--KEGFPITALREVKMLEQL-KHPNITDLIEVCSAKSTGTTGSKDRAT- ... |.|.| ||.| .|. .||. || |.. |. . .| | .||.|.. || .|||| |. ||. ... ITFGKKLGEGAFGEVYKGTWKG-------DPDNTKIPVAVKMLKEGAMHEQNCREDF----MREAKIMKQLGHHPNIVRLYGVCT---------DQGEPN -FYLVMALCAH-DLAGLLSNP---KIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLAR |.|| ...| || | .. | . .. .. | .|.. |.. .. ||| | |.|...... | .|||||| QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |
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Kinase | H25P06.2.AA | TyrKc | 85-422 | 17 | 4.2e-12 | -26.99 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 85-422 Range on HMM: 1-280/280 Sequence Identity: 17% (66 aa) YEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQL--KHPNITDLIEVCSAKSTGTTGSKDR-----AT ... |.| | ||.| .|. . ..|| |.. . .|| ... .| .|||| |. ||. .. | ITLGKKLGEGAFGEVYKGTWK--------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQG--------RNFMYIEP FYLVMALCAH-DLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQR-ENGAGPRPLYT-----NRV ..|| ...| || | ... . .. . .. .| . ||. .. ||| | |.|...... | .||||.| ..| |. .. LMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGK --VTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTR-----QP--------------IMQGDTEQKQLQL--ISGLCGSINKDVWPNCVNMPLWSAMS . . .|| . .. . || ||| | | |. |. ..||. . .| TMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------ SEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDI | ..|. . . . ||..||| | ... ----------------------------------F-------VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF |
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Kinase | H25P06.2.AA | CRK7 | 384-424 | 30 | 8e-06 | 15.76 | In-house | 301-343 (343) | Show / Hide |
Range on Protein: 384-424 Range on HMM: 301-343/343 Sequence Identity: 30% (13 aa) KNVKQHDS--ATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF ... .| . ..| || .|. ||.|| | |. . || EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF |
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Kinase | H25P06.2.AA | CDK7 | 391-424 | 29 | 1.4e-05 | 10.36 | In-house | 255-288 (288) | Show / Hide |
Range on Protein: 391-424 Range on HMM: 255-288/288 Sequence Identity: 29% (10 aa) SATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF .| ||.|.|.. ... .| || | .. | TAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF |
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Kinase | H25P06.2.AA | CDK10 | 398-424 | 33 | 0.002134 | 7.38 | In-house | 259-285 (285) | Show / Hide |
Range on Protein: 398-424 Range on HMM: 259-285/285 Sequence Identity: 33% (9 aa) LHLLEILLAIDPDKRPTSDEAEDDIWF ..||..|. .| || |..|. . .| RRLLNFLFMYNPKKRATAEECLESSYF |
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Kinase | H25P06.2.AA | PITSLRE | 395-424 | 33 | 0.002989 | 7.94 | In-house | 266-295 (295) | Show / Hide |
Range on Protein: 395-424 Range on HMM: 266-295/295 Sequence Identity: 33% (10 aa) DDALHLLEILLAIDPDKRPTSDEAEDDIWF | .. || .| .| .| | ..| .. || DTGFDLLNQMLTYNPKNRITASDALKHPWF |
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Kinase | H25P06.2.AA | CDK5 | 394-424 | 25 | 0.005168 | 4.82 | In-house | 257-287 (287) | Show / Hide |
Range on Protein: 394-424 Range on HMM: 257-287/287 Sequence Identity: 25% (8 aa) DDDALHLLEILLAIDPDKRPTSDEAEDDIWF | . ||. .| ..|..| . ..| .| DEKGMDLLQKMLQCNPNQRISAKAALHHPYF |
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Kinase | H25P06.2.AA | CDK-Unclassified | 404-424 | 23 | 0.051178 | 2.27 | In-house | 304-324 (324) | Show / Hide |
Range on Protein: 404-424 Range on HMM: 304-324/324 Sequence Identity: 23% (5 aa) LLAIDPDKRPTSDEAEDDIWF ... .|..|.. |. || MVMYQPYNRWKCMEILQHPWF |