Gene H12I13.1 (Nematode worm)
H12I13.1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| H12I13.1.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 295 | Kinase domain by global Sugen HMM | Fasta, JSON |
| H12I13.1.AA | Protein | Genbank | 592 | None | Fasta, JSON |
Protein domains of H12I13.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| UCH | H12I13.1.AA | UCH | 72-114 | 34 | 0.000131 | 12.69 | Pfam | 364-403 (403) | Show / Hide |
Range on Protein: 72-114 Range on HMM: 364-403/403 Sequence Identity: 34% (15 aa) DAKDRRWEKMDDVHVSDVSWE-EVERHSYGTGSDDTSSAVLIVY . |. .| | || ||..|. . ||.. ..| |..|| . .| HNKNNKWYKFDDDHVTRVTEWEEVLKENGG----DWWSAYMLFY |
|||||||||
| SPK | H12I13.1.AA | SPK | 216-332 | 18 | 3.3e-23 | 84.34 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 216-332 Range on HMM: 1-118/118 Sequence Identity: 18% (23 aa) YLNQCIKFLHTKSEN-VGKPFVRTTFYANFKNVVY----YKGTATTLGRGLQPLLHDAIISSEYKDFRKCQMLFVMSIQITNQSFLYRLAKN-SFSITLD .|.....||..|... . . .|.|. .. |.. .. .| | ..| . . ...| . ....|.|..|.... ..|| .. .. . ..|| ELTRFMDFLVEKTKDAIEPMVVTTKVFKEFSKYENHVNGCRSYTTYYKRFHNKLAPNMHKWNNYSIEERIRMMFALSGKVE-DDFLEQIQTHHIGTVQLD RFYRIEVCEYQSKKFSGVHKCPG ...||. . . | .|. | EKRRICKYTSND----GKLKLEG |
|||||||||
| Kinase | H12I13.1.AA | Haspin | 417-591 | 36 | 5.9e-80 | 271.93 | In-house | 1-216 (264) | Show / Hide |
Range on Protein: 417-591 Range on HMM: 1-216/264 Sequence Identity: 36% (79 aa) LQRKIGFGAYGSAYSVKYGGKTVVMKLIGIR--DN-------------EQLLFNELIITQQLGKLAKNRVCPNFLEYCGSHVMTDVP-------VGMRRD ...|||.|.||...||.. ||.||||.|.|. .. .. ..||.||....|||.....||||...||..|.|.|| . |... NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH PKAIR---------------HLAILMARGGGVLDN--WKFKDYRQCVSVFCQLVMSLKVVKDSINMVHRDIHLWNVLVS-RTKTTCLDYSMDGK-VKLNS ..... |....|..|| .||| |||....||.|..||||||... ||.....|.|.|..|||.. .||...|.|.|||| .|..| YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS YGVVMHLIDFSKSLYG .||....|||.|| .| HGVMVTIIDFCKSRCG |
|||||||||
| Kinase | H12I13.1.AA | HH498 | 415-442 | 39 | 5e-06 | 14.68 | In-house | 1-28 (284) | Show / Hide |
Range on Protein: 415-442 Range on HMM: 1-28/284 Sequence Identity: 39% (11 aa) IELQRKIGFGAYGSAYSVKYGGKTVVMK || ..||| |..| | ... .| | | IEFHEKIGSGSFGKVYKGEWRNKIVAVK |
|||||||||
| Kinase | H12I13.1.AA | MLK | 415-444 | 26 | 2e-05 | 14.96 | In-house | 1-30 (291) | Show / Hide |
Range on Protein: 415-444 Range on HMM: 1-30/291 Sequence Identity: 26% (8 aa) IELQRKIGFGAYGSAYSVKYGGKTVVMKLI |.....|| |..|. .. .. .|..| | . IQFHEWIGSGSFGKVWKGRWRNKDIVAKIV |
|||||||||
| Kinase | H12I13.1.AA | LISK | 420-449 | 28 | 0.000232 | 9.85 | In-house | 1-32 (296) | Show / Hide |
Range on Protein: 420-449 Range on HMM: 1-32/296 Sequence Identity: 28% (9 aa) KIGFGAYGSAYSVKYG--GKTVVMKLIGIRDN .|| |..|..| . . |. ...| | . .| EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPN |
|||||||||
| Kinase | H12I13.1.AA | RAF | 415-443 | 27 | 0.000327 | 9.22 | In-house | 1-29 (282) | Show / Hide |
Range on Protein: 415-443 Range on HMM: 1-29/282 Sequence Identity: 27% (8 aa) IELQRKIGFGAYGSAYSVKYGGKTVVMKL .... .|| | .|. |. .. |. | .| VMVMTRIGSGSFGTVYRGHWHGDVAVKML |
|||||||||
| Kinase | H12I13.1.AA | FAK | 540-556 | 64 | 0.003268 | 6.43 | In-house | 142-158 (285) | Show / Hide |
Range on Protein: 540-556 Range on HMM: 142-158/285 Sequence Identity: 64% (11 aa) SINMVHRDIHLWNVLVS |.. ||||| ||||| SKKFVHRDIAARNVLVS |
|||||||||
| Kinase | H12I13.1.AA | FAK | 415-430 | 50 | 0.029469 | 3.18 | In-house | 1-16 (285) | Show / Hide |
Range on Protein: 415-430 Range on HMM: 1-16/285 Sequence Identity: 50% (8 aa) IELQRKIGFGAYGSAY |.| |.|| | .| | ITLNRCIGEGQFGDVY |
|||||||||