Gene H05L14.1 (Nematode worm)
H05L14.1
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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H05L14.1.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 256 | Kinase domain by global Sugen HMM | Fasta, JSON |
H05L14.1.AA | Protein | Genbank | 794 | None | Fasta, JSON |
H05L14.1.kin_dom2 | Protein Kinase Domain | Sugen global kinase HMM prediction | 276 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of H05L14.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | H05L14.1.AA | Dual | 130-389 | 43 | 5.70000000001e-173 | 580.94 | In-house | 12-282 (282) | Show / Hide |
Range on Protein: 130-389 Range on HMM: 12-282/282 Sequence Identity: 43% (119 aa) LRNPVHLGEFNAVNEKNEKFIVRLEPSNRGKLKFGSDVVAEVEKLFAG---------QEKVPVLRNIEFCQTQHLNYWIISPFSLQILEILR--IVKALT .|...|...|..||.||...|...|.....|......|...|...||. ............|......||..||......||.| |...|. FRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLS VPCAFNVALQTLDAIQYLHQAGFLNRNIKPASFSVGLNEEETKIYMTDYRLVRTHIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAWIY ..|.||||.|.|.|||.||..|.|.||||||.|..||...||..||.|.|.||..|||..||.|.||...|..|..|||..|....||||||||.|.||| MHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIY MIYDLIDPENGLSWRKSPRCNMMIKEKENFKYHVLPHTYDKVPEEFKKLVDLVHGYSYDSLPDYAAFKEIV |..||.|||.|.||||...||||||.|.||.||...|.|...|...|.||..|.||.|||.|||..| MVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL |
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Kinase | H05L14.1.AA | CK1 | 141-385 | 20 | 2.3e-67 | 230.11 | In-house | 24-339 (339) | Show / Hide |
Range on Protein: 141-385 Range on HMM: 24-339/339 Sequence Identity: 20% (66 aa) AVNEKN------EKFIVRLEPSNRGKLKFGSDVVAEVEKLFAGQ-------------------EKVPVLRNIEFCQTQHLNYWIISPFSLQILEILR--- ....|| |.. . .|| . . .. ..... |.. |. .. |... . ... .. || ... . . .... HKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNR I-VKALTVPCAFNVALQTLDAIQYLHQAGFLNRNIKPASFSVGL-------------NEEETKIYMTDYRLVR-THIDP-----------STKKVRPART . .........|.|.|.|..|.| .||. |.|||. | .|. |.|. ..|| |. ..| .|. .|.. ||.|. MCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPRE ---GLKYGG-TARYASIAGLKKKDQGRKDDVEAWIYMIYDLIDPENGLSWRKSPRCNM-----MIKEKENFKYHVLPHTYDK---------VPEEFKKLV .. | ||||.||. . |.|||.||...|.||. .......|| |.. . .. ..|.|..|. ...| .. .|.|| |.. HKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIM DLVHGYSYDSLPDYAAF . .....|.. |||... KYIRSLKYYDRPDYEMI |
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Kinase | H05L14.1.AA | Worm6 | 215-385 | 30 | 7.1e-34 | 118.87 | In-house | 99-279 (279) | Show / Hide |
Range on Protein: 215-385 Range on HMM: 99-279/279 Sequence Identity: 30% (55 aa) KALTVPCAFNVALQTLDAIQYLHQAGFLNRNIKPASFSVGL-----NEEETKIYMTDYRLVR-THIDPSTKKVRPAR-TGLKYGGTARYASIAGLKKKDQ ........ .|.|.|.||. ||..||..|..||. | .| ..|. .||| |. . | . ...|. | | .. || |||..| |...| RKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQ GRKDDVEAWIYMIYDLIDPENGLSWRKSPRCNMMIKEKENFKYHV----LPHTYDKVPE-EFKKLVDLVHGYSYDSLPDYAAF .||||.| | ||. ..| . .| ||.. . . |.|. .. . ..| ||.. | . .||| . |||. CRKDDCESWFYMMVEMIVG--CLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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Kinase | H05L14.1.AA | CK1-Unique | 221-333 | 29 | 6.8e-27 | 90.27 | In-house | 118-233 (337) | Show / Hide |
Range on Protein: 221-333 Range on HMM: 118-233/337 Sequence Identity: 29% (34 aa) CAFNVALQTLDAIQYLHQAGFLNRNIKPASFSVGLNE--EETKIYMTDYRLVRT--HIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAW || . ..|.|..| |..||..|..||.... . . .. .|| || | .... .|. | .. |. .|.... . ...||.|| | | CAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNN-HQIRQPRPITPFRGCKDYCPCSCHQCREHGRRDDMESW IYMIYDLIDPENGLSWR ||.|.|.. . ||||. FYMLYHLVHNTRGLSWK |
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Kinase | H05L14.1.AA | TTBK | 227-385 | 32 | 4.5e-22 | 74.82 | In-house | 104-257 (257) | Show / Hide |
Range on Protein: 227-385 Range on HMM: 104-257/257 Sequence Identity: 32% (52 aa) LQTLDAIQYLHQAGFLNRNIKPASFSVGLNEEET-KIYMTDYRLVRTHIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAWIYMIYDLID .| |..|. |. ||| | ||| |..|.| ... |.|| |. | | . .. |||.| . ||.||||| . .. ||.|| || . VQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTN-ACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFV- PENGLSWRKSPRCNMMIKEKENFKYHVLPHTYDKVPEEFKKLVDLVHGYSYDSLPDYAAF . | ||| . . || . .| . .|.||. .| .. | |||. . -QGQLPWRKIKDKDQVGEMKEKYDHRML---LKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | H05L14.1.AA | TTBKL | 225-389 | 24 | 4.7e-19 | 61.03 | In-house | 107-288 (288) | Show / Hide |
Range on Protein: 225-389 Range on HMM: 107-288/288 Sequence Identity: 24% (46 aa) VALQTLDAIQYLHQAGFLNRNIKPASFSVGLNEE----ETKIYMTDYRLVRTHIDP----------STKKVRPART---GLKYGGTARYASIAGLKKKDQ .. |.|.|....| .||. | .||. . .|.... . .| |. ..| ... .....|..|. || ||.|.. |.| IGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQ GRKDDVEAWIYMIYDLIDPENGLSWRKSPRCNMMIKEKENFKYHVLPHTYDK---VPEEFKKLVDLVHGYSYDSLPDYAAFKEIV ||.|| .|.|||. | .. | |. . ... |.| | .| .. | || | . .. .| . ||| . |. GRHDDLWSWMYMIIELHCG---LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | H05L14.1.AA | CK1-D | 225-385 | 29 | 2.3e-16 | 54.08 | In-house | 100-261 (261) | Show / Hide |
Range on Protein: 225-385 Range on HMM: 100-261/261 Sequence Identity: 29% (49 aa) VALQTLDAIQYLHQAGFLNRNIKPASFSVGLNEEETKIYMTDYRLVRTHIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAWIYMIYDLI .|.| . |.|.| |. | ||| | .|| .|. |. | . . |. |.. | | |||||||| . .| |.||.|. |.. LADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFN D---PENGL-SWRKSPRCNMMIKEKENFKYHVLPHTYDKVPEEFKKLVDLVHGYSYDSLPDYAAF | || | . . .. | . | ..| . | |.||.. .. .. .| |||. . RGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGY---PSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | H05L14.1.AA | CK1-Unclassified | 226-315 | 39 | 1e-15 | 42.86 | In-house | 110-201 (244) | Show / Hide |
Range on Protein: 226-315 Range on HMM: 110-201/244 Sequence Identity: 39% (36 aa) ALQTLDAIQYLHQAGFLNRNIKPASFSVG-LNEEETKIYMTDYRLVRTHIDP-STKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEA | | .. |.||| .|. | ||| | .| |. . ...|. |. | ||. .|.| | | . . |||||||| . . |.|.|| |. ADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLES |
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Kinase | H05L14.1.AA | CK1-A | 228-320 | 34 | 1.2e-14 | 48.09 | In-house | 103-195 (261) | Show / Hide |
Range on Protein: 228-320 Range on HMM: 103-195/261 Sequence Identity: 34% (32 aa) QTLDAIQYLHQAGFLNRNIKPASFSVGLNEEETKIYMTDYRLVRTHIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAWIYMI | . | |.|. .|. | ||| | .|.. |... |. | . . |. |.. | |. . |||||||| .| |.||.|. |.. QMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVM |
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Kinase | H05L14.1.AA | CK1 | 224-315 | 34 | 5.8e-13 | 41.16 | In-house | 109-201 (271) | Show / Hide |
Range on Protein: 224-315 Range on HMM: 109-201/271 Sequence Identity: 34% (32 aa) NVALQTLDAIQYLHQAGFLNRNIKPASFSVGL-NEEETKIYMTDYRLVRTHIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEA ..| | .. |.|.| .|. | ||| | .|. . .....|. |. | .|..|.. | |.. . |||||||| . |.|.|| |. MIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMES |
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Kinase | H05L14.1.AA | Pkinase | 222-242 | 23 | 0.535259 | 4.61 | Pfam | 110-130 (293) | Show / Hide |
Range on Protein: 222-242 Range on HMM: 110-130/293 Sequence Identity: 23% (5 aa) AFNVALQTLDAIQYLHQAGFL . ....|.| ...|.|. |.. CKFYMYQILRGLEYCHSMGII |
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Kinase | H05L14.1.AA | Dual | 461-740 | 51 | 1e-199 | 669.75 | In-house | 1-282 (282) | Show / Hide |
Range on Protein: 461-740 Range on HMM: 1-282/282 Sequence Identity: 51% (146 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTESEGGKKAMLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSLDD ||||.|||||||.|||.|.......||...|.||||||.|.|.|||||||||||......|||.|......|..|.|.||.|..||||.|||..||||.. WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFLGTLRYASRACMLEVDQ .|||..............|||.|..|.|||..|||||.||||||..|.|..|.||.|.||.|.|.|.||..|.||..|||||..|..|||.||||...|| IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQ GRKDDLECWIYMVFDIFDPKNGVSWKKQRDRVKIREAKQLFFDGKAQYDYAPIS--LRPIIIYINSLQFQTTPEYANLVKTL |||||||||||||||..||..|.||.|..|.......|..|........|..|. |.|...|.|..|...||.|.... | GRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL |
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Kinase | H05L14.1.AA | CK1 | 461-736 | 28 | 2.3e-104 | 353.01 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 461-736 Range on HMM: 1-339/339 Sequence Identity: 28% (98 aa) WKVVRLLGSGGFG-DVYKV-----FDDKAKGP-KKTHYALKTESE-GGKKAMLRLKVEMQVMITISD---------ARKKSKGDVNRHFVDFIDRGKSEE ||||...|.|||| ..||| | | ..| |...||.|.|.. .. ....... .... .....|.. ..... .. .. |. WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED LKCKYIVMSLVGPSLDDCRR--KFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGV-------------GAKESTVFMLDFGIGR-SYL ...|.||.|.||.|.|.|. ... . . .| . ||||.||.....|. |..||||||.||..|. . .. .|.|.|||. | |. DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR DP-----------KTKQHRAPRK---KVKFLG-TLRYASRACMLEVDQGRKDDLECWIYMVFDIFDPKNGVSWKKQRDRVK-----IREAKQLFFDGKAQ |. ||.||| ||. |..| | |.||.|..|.| ..|||.|||..|.||... .....| |.. .| | ....|. |.| | DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM YDY-----------APISLRPIIIYINSLQFQTTPEYANL .. | .. .|. ||.||.....|.|... STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | H05L14.1.AA | Worm6 | 461-673 | 41 | 8.9e-75 | 254.74 | In-house | 1-211 (279) | Show / Hide |
Range on Protein: 461-673 Range on HMM: 1-211/279 Sequence Identity: 41% (92 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTES--EGGKKAMLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSL |||....|.||||.|||| |.. | . ..|.| |. |. |. | ||.|. |. .. |..| .|||....|||| .. .|||| |||..| WKVTKKIGEGGFGAVYKVEDKSDKKK--KQFAMKCEKQMENMKRQM--LKMECMVLKAV----KHHK---CRHFCKIEDRGKVDNRGFNYIVMTLVGKNL DDCRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGV-----GAKESTVFMLDFGIGR-SYLDPKTKQHRAPR-KKVKFLGTLRYAS | |. . . .| . ||||.||.|.|||| |..|||.||.||..|. ...|..|||||. | ... | .. | || ....| ||.|||. WDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAP RACMLEVDQGRKDDLECWIYMV .||. .|.||||.|.| ||. LACHKGQEQCRKDDCESWFYMM |
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Kinase | H05L14.1.AA | TTBKL | 461-740 | 26 | 1.1e-60 | 203.62 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 461-740 Range on HMM: 1-288/288 Sequence Identity: 26% (82 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTESEGGKKAMLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSLDD |..|...|.|||| ||.| | .. ||...|.| | || ....|. . ..| .|| ... || . .. ..||.|.||.|.| WMIVKMIGEGGFGQVYHVWD---MKDKKDCAAMKEE-------KNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRK--DYNFMVMTLCGPNLQD CRRKFGVN--LSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAK----ESTVFMLDFGIGRSYLDP----------KTKQHRAPRK---KV |.. .. .| ... . |.||.|......| |..|||.||.|...|. .. . .|. .|||. | |... .....|.||. |. LRKMMPNKKRFSDGTW-SRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKA KFLGTLRYASRACMLEVDQGRKDDLECWIYMVFDIFDPKNGVSWKKQRDRVKIREAKQLFFDGKAQYDY-----APISLRPIIIYINSLQFQTTPEYANL | ||.||.| . . .|||.||| .|.||. ... |. |. .| ..|. | . .| | .. .. .. ||... .| | . PFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG---LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMI VKTL . . YECF |
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Kinase | H05L14.1.AA | CK1-Unique | 461-686 | 29 | 7.9e-48 | 163.88 | In-house | 1-233 (337) | Show / Hide |
Range on Protein: 461-686 Range on HMM: 1-233/337 Sequence Identity: 29% (70 aa) WKVVRLLGSGGFGDVYKVFDDKAKG---PKKTHYALKTESEGGKKAMLRLKVEMQVMITISDAR---KKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLV |.| ..|.||.|.|..| .. . | . |. ||| . .| ||..| || |. |.. ||| .| . . ..||| .. WCVIKHIGYGGYGCVHRV-IFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYW-----RHFCEVHDFHQHRDW--WWIVMTMH GPSLDDCRRKFGV---NLS---NTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGA--KESTVFMLDFGIGRS-YLDPKTKQHRAPRKKVKFLG |||.. |... . |. | . . |.|. |. | |..||..||.|. . .. . .|||.|| |. . . | | ||....| | GPSMEECCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRG TLRYASRACMLEVDQGRKDDLECWIYMVFDIFDPKNGVSWK ...|....| .....||.||.| | || .... |.||| CKDYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK |
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Kinase | H05L14.1.AA | CK1-Unclassified | 461-667 | 32 | 1.4e-37 | 108.45 | In-house | 1-200 (244) | Show / Hide |
Range on Protein: 461-667 Range on HMM: 1-200/244 Sequence Identity: 32% (69 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTESEGGKKAMLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSLDD .|.. .|.| ||..||. . . ....|.| |.. | |. | ..| . . . ... . |. |. . ..||.| ||||.| YRVIEKIGQGSFGEIYKCINMQ----TNEEVAIKLEKKNSK--HPQLCYEAKIMQYLQNGHNC-DNFI-KGIPKMYWCGQEEQGDYNIMVMDLLGPSLED ----CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVG-VGAKESTVFMLDFGIGRSYLDP-KTKQHRAPRKKVKFLGTLRYASRAC | ||| . | || | .. | ||| ...|||||| || .| | . .|.. |||.. |.|. ||..| | . .. || |||| LFNMCNRKF-----SLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINA MLEVDQGRKDDLE | . |.|.|||| HLGIEQSRRDDLE |
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Kinase | H05L14.1.AA | CK1 | 461-667 | 33 | 3.4e-34 | 115.2 | In-house | 1-200 (271) | Show / Hide |
Range on Protein: 461-667 Range on HMM: 1-200/271 Sequence Identity: 33% (70 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTESEGGKKAMLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSLDD .|.| .|.| |||.|.. . .| . |.| | |.. | . |. | ... . .. . .. . |. |. .. ..||.| ||||.| YRVGRKIGQGSFGDIYLGINM-TNGEEN-HVAIKLEKNKSK-HP-QLHYEAKIYKILQGH-NC-DN-QCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLED ----CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGV-GAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFLGTLRYASRACM | ||| | || | .. | .|| ...|||||| || .|. | .. .|.. |||. |.|.||.|| | . .. || |||| LFNFCNRKF-----SLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTH LEVDQGRKDDLE | . |.|.||.| LGIEQSRRDDME |
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Kinase | H05L14.1.AA | TTBK | 548-736 | 34 | 1.1e-32 | 112.88 | In-house | 72-257 (257) | Show / Hide |
Range on Protein: 548-736 Range on HMM: 72-257/257 Sequence Identity: 34% (65 aa) YIVMSLVGPSLDDCRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVG-VGAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFLGT |.||.| | .| | ||| . || . .| |.||. |..|.||||||| |||.| . .. ..||||| | |. . . |.||. | || YMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACG-EVRPPREVAGFRGT LRYASRACMLEVDQGRKDDLECWIYMVFDIFDPKNGVSWKKQRDRVKIREAKQLFFDGKAQYDYAPISLRPIIIYINSLQFQTTPEYANL |||| . . ||.||| || | | .|. .. | |. .| . . | .. . |.||.....|.|. . VRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQ--LPWRKIKDKDQVGEMKEK-YDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | H05L14.1.AA | CK1-D | 549-736 | 31 | 2.8e-28 | 96.76 | In-house | 72-261 (261) | Show / Hide |
Range on Protein: 549-736 Range on HMM: 72-261/261 Sequence Identity: 31% (61 aa) IVMSLVGPSLDD----CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFL .|| |.||||.| |.||| . | ..| | . | .| ..|||||| || .|.| . ..|...|||. . | |..|.|| . | . MVMDLLGPSLEDLFNYCHRKFSLK-----TVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLT GTLRYASRACMLEVDQGRKDDLECWIYMVFDIFD---PKNGVSWKKQRDRVKIREAKQLFFDGKAQYDYAPISLRPIIIYINSLQFQTTPEYANL || |||| . ..| |.|||| |.. | |. .|.. |.. . . | . | .|.|. |.|. | GTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | H05L14.1.AA | CK1-A | 549-736 | 33 | 5.3e-26 | 88.77 | In-house | 72-261 (261) | Show / Hide |
Range on Protein: 549-736 Range on HMM: 72-261/261 Sequence Identity: 33% (65 aa) IVMSLVGPSLDD----CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFL .|| |.||||.| |.|.| . | ..| | . | .|. ...|||||| || .|.| .|..|||. . | |..|.|| |. . MVMDLLGPSLEDLFNFCKRRFTMK-----TVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLT GTLRYASRACMLEVDQGRKDDLECWIY--MVFDIFD-PKNGV-SWKKQRDRVKIREAKQLFFDGKAQYDYAPISLRPIIIYINSLQFQTTPEYANL || |||| | ..| |.||.| | | | | |. |. || | |.. . | . .. |. .|.|. .|.| | GTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISE-KKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | H05L14.1.AA | S_TKc | 461-702 | 16 | 1.2e-10 | -20.65 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 461-702 Range on HMM: 1-231/231 Sequence Identity: 16% (47 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTESEGGKKAMLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGP---S ....|..|.|.|| |||. . | . ..|.| . ... |.|.. . | ..| . .. |.|| ... . YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK-------EHIRREIQILKK-----------HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGD LDDCRRKFGVN-----LSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFLGTLRYA-- | | .| | . .. . .... |... . .|..| .|||.||.| . .. |||. | . | ||. | LFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAP -----SR------------ACMLE----VDQGRKDDLECWIYMVFDIFDPKNGVSWK---------KQRDRVKIREAKQ--------LFF .. . || . ... . .. . | ..| . || | .| EVLGYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | H05L14.1.AA | TTBK | 461-509 | 36 | 4e-06 | 17.8 | In-house | 1-46 (257) | Show / Hide |
Range on Protein: 461-509 Range on HMM: 1-46/257 Sequence Identity: 36% (18 aa) WKVVRLLGSGGFGDVYKVFDDKAKGPKKTHYALKTESEGGKKAMLRLKV ||||. | |||| .| | . . . |.| || .| |.. | WKVVKKIGGGGFGEIYEAKDMINH---HEQVAIKVESAQQPKQVLKMEV |
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Kinase | H05L14.1.AA | CK1-A | 461-476 | 56 | 0.000104 | 12.37 | In-house | 1-16 (261) | Show / Hide |
Range on Protein: 461-476 Range on HMM: 1-16/261 Sequence Identity: 56% (9 aa) WKVVRLLGSGGFGDVY ...|| .||| |||.| YRLVRKIGSGSFGDIY |
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Kinase | H05L14.1.AA | Pkinase | 461-482 | 40 | 0.000654 | 14.91 | Pfam | 1-22 (293) | Show / Hide |
Range on Protein: 461-482 Range on HMM: 1-22/293 Sequence Identity: 40% (9 aa) WKVVRLLGSGGFGDVYKVFDDK ....| .|||.|| ||| . . YHIGRKIGSGSFGCVYKCHHKG |
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Kinase | H05L14.1.AA | Worm6 | 718-736 | 26 | 0.003634 | 7.61 | In-house | 261-279 (279) | Show / Hide |
Range on Protein: 718-736 Range on HMM: 261-279/279 Sequence Identity: 26% (5 aa) IIIYINSLQFQTTPEYANL | || .......|.|... IMDYIDQYSYWDRPDYKFI |
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Kinase | H05L14.1.AA | CK1-D | 461-476 | 50 | 0.004878 | 6.37 | In-house | 1-16 (261) | Show / Hide |
Range on Protein: 461-476 Range on HMM: 1-16/261 Sequence Identity: 50% (8 aa) WKVVRLLGSGGFGDVY ... | .||| |||.| YRIGRKIGSGSFGDIY |
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Kinase | H05L14.1.AA | CK1 | 719-734 | 31 | 0.087094 | 2.17 | In-house | 256-271 (271) | Show / Hide |
Range on Protein: 719-734 Range on HMM: 256-271/271 Sequence Identity: 31% (5 aa) IIYINSLQFQTTPEYA . |...|.|. .| |. LNYCRQLHFEEKPDYM |
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Kinase | H05L14.1.AA | Pkinase | 581-604 | 41 | 0.2082 | 6.06 | Pfam | 116-139 (293) | Show / Hide |
Range on Protein: 581-604 Range on HMM: 116-139/293 Sequence Identity: 41% (10 aa) QTLESIRDLHNLGYLHRDIKPANF |.|. . .|. | .|||.||.|. QILRGLEYCHSMGIIHRDLKPENI |