Gene gcy-4 (Nematode worm)

gcy-4

Species: Nematode worm
Alias: ZK970.5, CE02405, gcy-4, aSWK282
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 10308758-10304041, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 272 Kinase domain by global Sugen HMM Fasta, JSON
gcy-4.AA Protein Genbank 1143 None Fasta, JSON

Protein domain

Protein domains of gcy-4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-4.AA ANF_receptor 57-435 18 5.9e-70 243.51 Pfam 1-364 (364) Show / Hide 
Range on Protein: 57-435
Range on HMM: 1-364/364
Sequence Identity: 18% (77 aa)

YTGGAVPLALQYLKSHGYMLNFDFEFHVEYTEC----DLANTVRAGLNFMKTNNYDVIIGPPCAPALKMMGTLSTIYKKPVLGWGFVSESEISD--MNRF
  ..|...|...... .  |............|    |  . | |.  ... .. ..|||| |  .  ... . . ...|...|| ..... .|   ||.
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWG-CTCPCLTDKAKNRY

PFVASVLPSTKTL-GVVTSKLLEI-YGWDRVALLYFKNELDYCSSV---VNDVEKSLYN-ESKSVQI--VMKAEIDGSNSESTSATLQV-VKTRARVILF
|... ..||   . | . .....  .||..||..|.... .|. ..   ...... |   . . |..  |.. . . .. .. .  ..  .| .||||..
PYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIVM

CAHAGGE---KRFYLIQAGLLGMNSSEYVHVMLSMRSVGFGVQTSVGKKPLTLSGLPPIWESFTVNPDGMEDLAKSVAAKMIVIDTSSEVRDKTFLQYMT
|...      .| ...||  |||.| .||... .. . ....| .                    ..| |.. .   |.|.....|.  . .. | ..|.
CCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W-------------------WYDDDMDNDKFREAMKGVLGFTMH-P-SPEFQEFMQ

KNIVYAIREPPLSCKVPECLITNATGMGAYARHLFDVFYMYGMAVSSLNSTDPNVYGNL---------SLLIPKFT-TAFEGMTGEVKLNEDLARKPLYQ
..                    . |.| .|| ...| .|.|..|.  ....|||..  .         .||    . . |||.||.|.....  |.| |.
RWKK------------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDNGGRRPDYM

VYGLNSE
.. .|  
YWIMNWD
Kinase gcy-4.AA RGC 589-825 35 5.5e-123 414.87 In-house 1-300 (300) Show / Hide 
Range on Protein: 589-825
Range on HMM: 1-300/300
Sequence Identity: 35% (106 aa)

ENDLVLTTAHQVQ------ELSQAEMMKFVKLRKLDHENLNKFIGLSIDGS------RFVSVWKMCSRGSLQDIISKGSFSMDYFFMFCMIRDIAEGLHY
|.|.|... |. .      ... ..|... ..|.|.|.|||||||..||.       ....||..|||||||||.......|| .|....||||..|..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

IHKSFLRHHGNLRSATCLVNDSWQVKLADFGLQ----------------------FLQDEEEKPFKKNMLWAAPEVIRGSLSIEQMDS---------SAD
.|.|..|.||||.|..|.|...|.||..||||.                      ......|.|..|.||| |||..|....  |...         ..|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFAIVASEILTKREAWDLS-----------RRKE---EIKYAVKKGGQFVLRPDLHID-----IEVNQTLLALVKDCWCENPEERPS-AENVCKVLFD
.|||.|...||.|....|||.            ..|   |.|| .|||||...||..| |     ||.|..||.|..||| |.|||||. .....| | .
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-4.AA RGC 589-825 35 5.5e-123 414.87 In-house 1-300 (300) Show / Hide 
Range on Protein: 589-825
Range on HMM: 1-300/300
Sequence Identity: 35% (106 aa)

ENDLVLTTAHQVQ------ELSQAEMMKFVKLRKLDHENLNKFIGLSIDGS------RFVSVWKMCSRGSLQDIISKGSFSMDYFFMFCMIRDIAEGLHY
|.|.|... |. .      ... ..|... ..|.|.|.|||||||..||.       ....||..|||||||||.......|| .|....||||..|..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

IHKSFLRHHGNLRSATCLVNDSWQVKLADFGLQ----------------------FLQDEEEKPFKKNMLWAAPEVIRGSLSIEQMDS---------SAD
.|.|..|.||||.|..|.|...|.||..||||.                      ......|.|..|.||| |||..|....  |...         ..|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFAIVASEILTKREAWDLS-----------RRKE---EIKYAVKKGGQFVLRPDLHID-----IEVNQTLLALVKDCWCENPEERPS-AENVCKVLFD
.|||.|...||.|....|||.            ..|   |.|| .|||||...||..| |     ||.|..||.|..||| |.|||||. .....| | .
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-4.AA TKL 612-823 19 4.2e-28 98.3 In-house 77-364 (364) Show / Hide 
Range on Protein: 612-823
Range on HMM: 77-364/364
Sequence Identity: 19% (58 aa)

VKLRKLDHENLNKFIGLSIDGSR-------------FVSVWKMCSRGSLQDIISKGSFSMDYFFMFCMIRDIAEGLHYIHKSFL-------RHHGNLRSA
. ...|.|.|. .|.| .....              .  |   |..||| ...           .. ...||| |..| | .           | .| |.
MMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSK

TCLVNDSWQ--------------VKLADFGLQFLQDEE----------------------EKPFKKNMLWAAPEVIRGS--LSI----------EQMDSS
 .||.. |.              .|..||||    ...                        .   .  | ||||.||.  ..           .. . .
NILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEK

ADIYSFAIVASEILTKREAWD-LSRRKEEIK----YAVKKGGQFVLRPDL----------HIDIEVNQTLLALVKDCWCENPEERPSAENVCKVL
.|.|||.||  |||| .. .. .  . ...        .. ..  ||| .               . . .  | .||| ..||.|||.. . | |
CDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-4.AA TKL-Unique 614-758 25 1.9e-21 72.5 In-house 49-223 (290) Show / Hide 
Range on Protein: 614-758
Range on HMM: 49-223/290
Sequence Identity: 25% (45 aa)

LRKLD-HENLNKFIGLSI----DGSRFVSVWKMCSRGSLQDIIS---------KGSFSMDYFFMFCMIRDIAEGLHYIHKSFL-RHHGNLRSATCLVNDS
. ||. |.|. ...| ..    . ...  |   |..||| | ..         . .  ...  .  |..||| |..|.| .     |..|.|   ||.  
MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNN

-----WQVKLADFGLQFLQDEE-EKPFK-----------KNMLWAAPEVIRGSLSIEQMDSSADIYSFAIVASEILT
     |..|..||||  ... . .....           .. .|.||||.|..   .| . ..|.|||.||  ||.|
SNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEKSDVYSFGIVLWEIAT
Kinase gcy-4.AA TK 592-823 13 2.8e-21 67.4 In-house 60-486 (486) Show / Hide 
Range on Protein: 592-823
Range on HMM: 60-486/486
Sequence Identity: 13% (59 aa)

LVLTTAHQVQELSQ---------------AEMMKFVKLRKLDHENLNKFIGLSIDG------------SRFVSVWKMCSRGS----LQDIIS--KGSFS-
| ...|.. .|  .               ||.||  ......|.|. ...| . .|              .  |  ... |.    |.|     .. |. 
LKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQH

------------------------------------------------------------------------MDYFFMFCMIRDIAEGLHYIHKS-----
                                                                        ..   .  | ..||.|. |.|.      
EQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI

--FLRHHGNLRSATCLVNDSWQ-----------VKLADFG--------LQFLQDEEEKPFKKN--------------------------ML---WAAPEV
  |   |..|    |||... .           .|.||||        |    ....   .|.                          .|   | |||.
QNFV--HRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPEC

IRGSLSIEQ-----MDSSADIYSFAIVASEILT---KREAWDLSRRK-------EEIKYAVKKGGQ------------FVLRPDLHIDI---------EV
...    |.       .  |..|| ..  ||.|   .  ....| ..       .|.   ...||.            . . .  |            ..
LNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHC

NQTLLAL-VKDCWCENPEERPSAENVCKVL
. .....  ..|| ..||.||. . . . |
PPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-4.AA DRK 643-758 39 1.5e-13 42.29 In-house 80-197 (258) Show / Hide 
Range on Protein: 643-758
Range on HMM: 80-197/258
Sequence Identity: 39% (48 aa)

SRGSLQDIISKGSFSMDYFFMFCMIRDIAEGLHYIHKSF-LRHHGNLRSATCLVNDSWQVKLADFGLQF-LQDEEEKPFKKNML----WAAPEVIRGSLS
.||||  |    | .||   |  |  |.| |. | | .     |  | |   || ..|||| |||||    .  ... | . |     | |||| |    
PRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRY

IEQMDSSADIYSFAIVASEILT
 |     ||.||||||  |..|
TEK----ADVYSFAIVLWECVT
Kinase gcy-4.AA RAF 668-825 26 1.6e-13 39.95 In-house 110-282 (282) Show / Hide 
Range on Protein: 668-825
Range on HMM: 110-282/282
Sequence Identity: 26% (47 aa)

RDIAEGLHYIHKSFLRHHGNLRSATCLVNDSWQVKLADFGLQFLQDEEE----KPFKK---NMLWAAPEVIR-------GSLSIEQMD---SSADIYSFA
| .. |. | |.    |   |.|   .  .  .||  ||||  ..  .     ..|.      || ||||||       | . .          |.||| 
RQVCQGMDYLHAKNIIHR-DLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVYSFG

IVASEILTKREAW-DLSRRKEEIKYAVKKGGQFVLRPDL-HIDIEVNQTLLALVKDCWCENPEERPSAENVCKVLFD
||  |..|..      .  .. | . .   |.  |||||  .  .. . .  |..|||  ..||||. ... | .  
IVMYELMTRHMPYGCHIWNRDQIIFMC---GRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
S_TKc gcy-4.AA S_TKc 518-824 15 1.4e-10 -21.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 518-824
Range on HMM: 1-231/231
Sequence Identity: 15% (53 aa)

SKIRNR-------RVEQSRLHSEWQIHAIKLRLPMHRRASKSSQESETESASETENFTSKSGDTMTSEFKETYTIQYLENDLVLTTAHQVQELSQAEMMK
 .| .        .| . | ..  .| |||                                                             |  . |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------------------------------------------EHIRREIQI

FVKLRKLDHENLNKFIGLSIDGSRFVSVWKMCSR--GSLQDIISKGSFS-----MDYFFMFCMIRDIAEGLHYIHKSFLRHHGNLRSATCLVNDSWQVKL
  |    .|.|. |...   | ...  |  .|.   |.| |.| |         ..     .... |...| |.|.     |  |  .  |...  ..|.
LKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKI

ADFGL--QFLQDEEEKPFKKNMLWAAPEVIRGSLSIEQMDS-SADIYSFAIVASEILTKREAWDLSRRKEEIKYAVKKGGQFVLRPDLHIDIEVNQTLLA
.||||  |.      . |     . ||||.       . .  ..|..|. ..  | |. .  ..      ...   || |               . .. 
CDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------SPEAKD

LVKDCWCENPEERPSAENVCK--------VLF
... |.. .||.||.|  . .          |
FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase gcy-4.AA Dicty4 642-761 28 7.8e-10 29.16 In-house 84-215 (277) Show / Hide 
Range on Protein: 642-761
Range on HMM: 84-215/277
Sequence Identity: 28% (40 aa)

CSRGSLQDIISK------GSFSMDYFFMFC---MIRDIAEGLHYIHK-S--FLRHHGNLRSATCLVNDSWQVKLADFGL-QFLQDEEEKPF-KKNM----
...|.|  .. .       | ..|.  .     | .|.| |. . |     ..  |  | |.  || ..|.|| .|||| |  . .|.. .  . .    
MPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVII--HRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTP

LWAAPEVIRGSLSIEQMDSSADIYSFAIVASEILTKRE
.| |||| ..    .  ...|| |||.||  ||||. |
CWMAPEVMMH----QPYNEKADVYSFGIVLWEILTRQE
TyrKc gcy-4.AA TyrKc 588-823 20 2.7e-09 -72.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 588-823
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

LENDLVL--------------------TTAHQVQELSQAEMMK-FVKLRKL--DHENLNKFIGLSIDG-------SRFVSVWKMCSRGSLQDIISKGS--
.. . .|                    .  .      ....|.    ..||  .|.|. ...|  ...            |   .. |.|.| . |    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

FSMDYFFMFCMIRDIAEGLHYIHKSFLRHHGNLRSATCLVNDSWQVKLADFGL-QFLQDE-------EEKPF-----KKNML---WAAPEVIRGSLSIEQ
..|. .  ||   .||.|  |.|.  . |   |    |||..  .|| .||||  .. |.       . .       .| ||   | |||.|        
LCMKDLLSFCW--QIACGMEYLHSKNCIHR-DLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGK

MDSSADIYSFAIVASEILTKREAWDLS-----RRKEEIKYAVKKGGQFVLRPDLHIDIE-----VNQTLLALVKDCWCENPEERPSAENVCKVL
  .  |..|| ..  ||.|  .             .|.   ||.|.    .|. .   .       . .  . |.|| |.||.||. ..... .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY-RMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase gcy-4.AA Pkinase 725-823 17 3.9e-09 33.39 Pfam 177-293 (293) Show / Hide 
Range on Protein: 725-823
Range on HMM: 177-293/293
Sequence Identity: 17% (21 aa)

WAAPEVIRGSLSIEQMDSSADIYSFAIVASEILTKREAWDLSR----RKEEIKYAVKKGGQFVLRPDLHIDIEVN-----------------QTLLALVK
..||||||   . .  ....|..|. ..  | |..|  .. ..    .  . .. ... ..  |. |   ....                  .... ..|
YMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

DCWCENPEERPSAENVCKV--L
.|.| .|..||.|| ...   .
WCLCKDPKKRPTAEQILQHPWF
Kinase gcy-4.AA TKL-ciliate1 785-823 33 3.9e-08 23.95 In-house 238-279 (279) Show / Hide 
Range on Protein: 785-823
Range on HMM: 238-279/279
Sequence Identity: 33% (14 aa)

RPDL---HIDIEVNQTLLALVKDCWCENPEERPSAENVCKVL
|| |    |     | .  | ..|||.||  ||... .  .|
RPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase gcy-4.AA UTK 616-709 22 2.4e-07 21.22 In-house 65-175 (296) Show / Hide 
Range on Protein: 616-709
Range on HMM: 65-175/296
Sequence Identity: 22% (25 aa)

KLD-HENLNKFIGLSIDGSRFVSVWKMCSRGSLQDIISKGSFSMD----YFF---MFCMIRDIAEGLHYIH-KSFLRHHGNLRSATCLVNDS-------W
... |.|. ...|.  ... .  |. ....|.|..   . . . .    ..    . || .|||.|..|.| . |   |..|    |||...       .
QFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFV--HRDLAARNCLVHMHRMMWHCMM

QVKLADFG---LQ
..|.||||   ..
VCKIADFGRGGMS
Kinase gcy-4.AA UTK 797-823 29 4e-06 16.91 In-house 270-296 (296) Show / Hide 
Range on Protein: 797-823
Range on HMM: 270-296/296
Sequence Identity: 29% (8 aa)

TLLALVKDCWCENPEERPSAENVCKVL
..  |...||  .|.|||..| . ...
PVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase gcy-4.AA DRK 800-825 38 1.5e-05 14.81 In-house 233-258 (258) Show / Hide 
Range on Protein: 800-825
Range on HMM: 233-258/258
Sequence Identity: 38% (10 aa)

ALVKDCWCENPEERPSAENVCKVLFD
.| .||| |.|  ||| . . . |  
QLMNDCWNEDPQHRPSMQECLERLEA
Kinase gcy-4.AA Pkinase_Tyr 803-823 38 0.000899 13.4 Pfam 250-270 (270) Show / Hide 
Range on Protein: 803-823
Range on HMM: 250-270/270
Sequence Identity: 38% (8 aa)

KDCWCENPEERPSAENVCKVL
|.|| ..||.||. . .   |
KQCWHYDPEDRPTFSEIHEQL
Kinase gcy-4.AA TKL-Unique 795-823 27 0.000949 9.31 In-house 262-290 (290) Show / Hide 
Range on Protein: 795-823
Range on HMM: 262-290/290
Sequence Identity: 27% (8 aa)

NQTLLALVKDCWCENPEERPSAENVCKVL
.. .  | ..||  .|..||| ... . |
PKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-4.AA TKL-ciliate1 619-679 25 0.000992 8.64 In-house 58-121 (279) Show / Hide 
Range on Protein: 619-679
Range on HMM: 58-121/279
Sequence Identity: 25% (16 aa)

HENLNKFIGLSIDGSRFVSVWKMCSRGSLQDIISKGSF---SMDYFFMFCMIRDIAEGLHYIHK
|.||   .| |     |. .   |  |.. || ..       .       ...||| |. |.|.
HINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHM
Kinase gcy-4.AA Dicty4 800-815 43 0.001312 8.1 In-house 250-265 (277) Show / Hide 
Range on Protein: 800-815
Range on HMM: 250-265/277
Sequence Identity: 43% (7 aa)

ALVKDCWCENPEERPS
.|...|| ..|. |||
HLIQWCWDHDPQHRPS
Kinase gcy-4.AA Pkinase 614-679 24 0.004266 12.03 Pfam 54-126 (293) Show / Hide 
Range on Protein: 614-679
Range on HMM: 54-126/293
Sequence Identity: 24% (18 aa)

LRKLDHENLNKFIGLSIDGSRFVSVWKMCSRG----SLQDIIS---KGSFSMDYFFMFCMIRDIAEGLHYIHK
...|.|.|  ....   |...   |   |  |    .| |.||   .|.|....    .... |..|| |.|.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS
Kinase gcy-4.AA TKL-ciliate1 725-753 30 0.007298 5.63 In-house 180-209 (279) Show / Hide 
Range on Protein: 725-753
Range on HMM: 180-209/279
Sequence Identity: 30% (9 aa)

WAAPEVIR-GSLSIEQMDSSADIYSFAIVA
| |||...    .  .    .|||...||.
WMAPEQMDPHIFPNYPINEKIDIYAYGIVM
Kinase gcy-4.AA Pkinase_Tyr 663-708 36 0.440403 4.29 Pfam 113-157 (270) Show / Hide 
Range on Protein: 663-708
Range on HMM: 113-157/270
Sequence Identity: 36% (17 aa)

MFCMIRDIAEGLHYIH-KSFLRHHGNLRSATCLVNDSWQVKLADFGL
. .| ..||.|. | . | .   |  |.   |||... .|| .||||
LLQMCWQIAKGMEYLESKNCI--HRDLAARNCLVTENNVVKICDFGL
CYCc gcy-4.AA CYCc 862-1056 41 6.1e-98 332.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 862-1056
Range on HMM: 1-231/231
Sequence Identity: 41% (96 aa)

LEKKKSDILLGRMLPKQVAERLKAGQ-AVEPESFDLVTVFFSDLVKFTDLASKCSPFQVVNLLNDVFSNFDSIIEKHD-----VYKVESIGDGFLCVSGL
 ||.| | || .|||. ||..||.|. .|.|...| ||. |.|.| ||.|.|.|.|.||||.|||....||.||..|.     .|||| |||.. .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PNRNG-------------------MEHIRQIVGMSLCFMEFCRNFRIPHL----PRERVELRVGINSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGK
| ||.                    .|...|. ..|  .|....| ..|     | . . .|.||..||.|.||||. |||||.||||||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PSMIHMSEAAHSLL-------VNNYPYQFET
|  ||.||.....|       .... ..|| 
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-4.AA Guanylate_cyc 889-1077 42 6.8e-96 329.69 Pfam 1-214 (214) Show / Hide 
Range on Protein: 889-1077
Range on HMM: 1-214/214
Sequence Identity: 42% (91 aa)

VEPESFDLVTVFFSDLVKFTDLASKCS----PFQVVNLLNDVFSNFDSIIEKH--DVYKVESIGDGFLCVSGLPNR-----NGMEHIRQIVGMSLCFMEF
|.....| ||..|.|.| ||...|.||    |.|.|..||| ...||.....|  ..|||. ||| ..||||||..     ..  |..... |.| .||.
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

CRNFRIPHLPRER-----VELRVGINSGPCVAGVVG--LSMPRYCLFGDTVNTASRMESNGKPS--MIHMSEAAHSLLVNNYPYQFET--NSRGEVIIKG
|. ....|..||.     ...|.||..||.||||.|  ..|||||..|||||.||||||.|.|.   ||.||.....| . ...|||.   .|||. .||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGV---METYWLLG
||    ||||.| |
KGKMGEMETYFLHG
HNOBA gcy-4.AA HNOBA 857-883 59 2e-06 24.78 Pfam 208-234 (234) Show / Hide 
Range on Protein: 857-883
Range on HMM: 208-234/234
Sequence Identity: 59% (16 aa)

TKELTLEKKKSDILLGRMLPKQVAERL
..||  ||||.| ||  |.||.||.||
HRELEEEKKKTDDLLYSMFPKSVANRL