Gene gcy-3 (Nematode worm)

gcy-3

Species: Nematode worm
Alias: CE01636, gcy-3, R134.1, aSWK284
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 9507185-9502661, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
gcy-3.AA Protein Genbank 1140 None Fasta, JSON

Protein domain

Protein domains of gcy-3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-3.AA ANF_receptor 54-433 19 2.3e-70 244.86 Pfam 1-364 (364) Show / Hide 
Range on Protein: 54-433
Range on HMM: 1-364/364
Sequence Identity: 19% (78 aa)

VCGGAVPLAIERLKQAGYVTNFDFEYYVEYTEC----DLASTVRTGINFLKNLEVDVIIGPPCSEAIRTMATLATLYKKPVLGWGFVSQADLSD--MTRF
 |..|...|||...... . ...... .....|    |    |  .  ...  .|..|||| ||.. ...| .|.....|...|| ..   |.|   .|.
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWG-CTCPCLTDKAKNRY

PYLITVLPTSQTL-GYAASKLLEL-YKWDKVALLYYKSEVNHCGGV---MNDVETTFNDPSTYSIQI--VLKAEIDASDNVTTNAVISS-VKTRARIILW
||.. ..|..  . |.|......  ..|..||..|.... ... |.   |..........  . ...  | . . . .|  .   .|   .| .||.|..
PYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIVM

CAQLGSE---KRDYMIKISQLGLDTDEYVHVLISMRSIGFGVQTFVGKTTFKLSGLTPVWESFSNVTDGLENV--AKRGATNVLVIDLNSEVSDKAYLDY
|..       .| .|... .||.....||...... . ....| .                     .|....   ... . .||.. .   . .. . ..
CCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W--------------------WYDDDMDNDKFREAMKGVLGFTMH--P-SPEFQEF

MQRNILNVVKLPPLNCSTVDCVSSTATGMGAYARHLFDVVYLYGIALTRVNSTDSAVYDDM---------SKLIPQFV-TSFNGMTGLVAINQNLSRMPL
|||.                    | |.| .|| ...| ||||. || .....|......          . |      ..|.|.|| | .. |  |.| 
MQRWKK------------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDNGGRRPD

YQLYGLDEQ
|... .. .
YMYWIMNWD
Kinase gcy-3.AA RGC 585-824 34 7.89999999999e-125 421.0 In-house 1-300 (300) Show / Hide 
Range on Protein: 585-824
Range on HMM: 1-300/300
Sequence Identity: 34% (104 aa)

EKDMVLTMKFQYM------NLNKADMDKFVKLRKLDHENLNKFIGLSIDSS------QFISVTKLCSRGSLLDILYKGNFSMDFFFMYCIIKDVAEGMSY
|.|.|...|....      ......|... ..|.|.|.|||||||..||.       ....|...|||||| |||......|| .|.|. |.|...|| |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKSFLRLHGNLRSATCLVNDSWQVKLAEFGF-----------------------DQLLEEITPTKRRLLWAAPEVLRGSLTVSQMD---------PSAD
||.|..| ||||.|..|.|...|.||.. ||.                       .|  .. .|.....|| |||.||.... .|..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VFSFAIIASEILTRKEAWDLK-----------ERKEGYDEIIYRVKKGGSFPIRPDIITDVP----DVNPTLIALVKDCWAEAPEDRPT-AENICEQLRD
|.||.||..||.|||..|||.           ...| ..|..| .||||..|.||.|..|      ..||.|..|..||||| ||.||. ...|..||..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-3.AA RGC 585-824 34 7.89999999999e-125 421.0 In-house 1-300 (300) Show / Hide 
Range on Protein: 585-824
Range on HMM: 1-300/300
Sequence Identity: 34% (104 aa)

EKDMVLTMKFQYM------NLNKADMDKFVKLRKLDHENLNKFIGLSIDSS------QFISVTKLCSRGSLLDILYKGNFSMDFFFMYCIIKDVAEGMSY
|.|.|...|....      ......|... ..|.|.|.|||||||..||.       ....|...|||||| |||......|| .|.|. |.|...|| |
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHKSFLRLHGNLRSATCLVNDSWQVKLAEFGF-----------------------DQLLEEITPTKRRLLWAAPEVLRGSLTVSQMD---------PSAD
||.|..| ||||.|..|.|...|.||.. ||.                       .|  .. .|.....|| |||.||.... .|..         ...|
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VFSFAIIASEILTRKEAWDLK-----------ERKEGYDEIIYRVKKGGSFPIRPDIITDVP----DVNPTLIALVKDCWAEAPEDRPT-AENICEQLRD
|.||.||..||.|||..|||.           ...| ..|..| .||||..|.||.|..|      ..||.|..|..||||| ||.||. ...|..||..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-3.AA TKL 608-822 22 5.7e-36 125.82 In-house 77-364 (364) Show / Hide 
Range on Protein: 608-822
Range on HMM: 77-364/364
Sequence Identity: 22% (66 aa)

VKLRKLDHENLNKFIGLSIDSSQ-------------FISVTKLCSRGSLLDILYKGNFSMDFFFMYCIIKDVAEGMSYLHKSFL-------RLHGNLRSA
. ...|.|.|. .|.| ......             .  |. .|..||||..|        .  .  ...|.| ||.||| .          .| .| |.
MMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSK

TCLVNDSWQ--------------VKLAEFGFDQLLEEITP--------------------TKRRL---LWAAPEVLRGSLTVS------------QMDPS
 .||.. |.              .|.. ||. . ... .                     | ..     | |||||||..  .            . ...
NILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEK

ADVFSFAIIASEILTRKEAWD-LKERKEGYD----EIIYRVKKGGSFPIRPDIITD------VPDVNPTLIALVKDCWAEAPEDRPTAENICEQL
.||.||.|.  |||||.. .. .... .       |... | . |  | .|.|  .       ||. | .. | .|||.. ||.||... | ..|
CDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-3.AA TKL-Unique 610-755 27 1.1e-22 76.89 In-house 49-225 (290) Show / Hide 
Range on Protein: 610-755
Range on HMM: 49-225/290
Sequence Identity: 27% (49 aa)

LRKLD-HENLNKFIGLSI----DSSQFISVTKLCSRGSLLDILY---------KGNFSMDFFFMYCIIKDVAEGMSYLHKSFL-RLHGNLRSATCLVNDS
. ||. |.|. ...| ..    . .... |.  |..||| | |          . |  ...  .. ...|.| || ||| .    .|..|.|   ||.  
MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNN

-----WQVKLAEFGFDQLLEEI-TPTKRRL------------LWAAPEVLRGSLTVSQMDPSADVFSFAIIASEILTRK
     |..|.. ||.  ..  | . |....            .|.||||||..   .| . ..||.||.|.  ||.|||
SNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF--CQYSEKSDVYSFGIVLWEIATRK
Kinase gcy-3.AA TK 609-822 14 8.7e-18 55.49 In-house 93-486 (486) Show / Hide 
Range on Protein: 609-822
Range on HMM: 93-486/486
Sequence Identity: 14% (58 aa)

KLRK---LDHENLNKFIGLSIDS------------SQFISVTKLCSRGS----LLDILY--KGNFSM---------------------------------
|. .   ..|.|. ...| . ..              .. |. ... |.    |.| |   ...|.                                  
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

-----------------------DFFFMYC----------------IIKDVAEGMSYLHKSFLR-----LHGNLRSATCLVNDSWQ-----------VKL
                       |.  | .                .  ..|.||.|||.   .      |..|    |||... .           .|.
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKI

AEFGFDQ-----LLEEITPT---------------------------------KRRLLWAAPEVLRGSLTVSQ-----MDPSADVFSFAIIASEILTRKE
| ||        |  .| .                                  |  . | |||.|..    ..       .  ||.|| .   ||.|. .
ADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQ

---AWDLKERK----EGYDEIIYRVKKGG-----------SFPIRPDIITDVPD----------VNPTLIAL-VKDCWAEAPEDRPTAENICEQL
   ....  ..    . ... ...  . |               |.    . ||          ..|.....  ..||.. |||||| . . |||
EPYYGGMSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-3.AA Dicty4 612-756 27 9.4e-14 42.42 In-house 54-215 (277) Show / Hide 
Range on Protein: 612-756
Range on HMM: 54-215/277
Sequence Identity: 27% (46 aa)

KLDHENLNKFIGLSI----DSSQFISVTKLCSRGSLLDILYK------GNFSMDFFFMYC---IIKDVAEGMSYLHKSF-LRLHGNLRSATCLVNDSWQV
|. | |. .| | ..     .. .  || ....|.|. .| .       . ..|.  .     . .|.| || .|| .    .|  | |.  || ..|.|
KIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRV

KLAEFGFDQLLEEITPTKR-------RLLWAAPEVLRGSLTVSQMDPSADVFSFAIIASEILTRKE
| . ||. |.  ...  |          .| ||||...       . .|||.||.|.  |||||.|
KVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP----YNEKADVYSFGIVLWEILTRQE
Kinase gcy-3.AA RIPK 722-822 29 2e-13 42.08 In-house 190-290 (290) Show / Hide 
Range on Protein: 722-822
Range on HMM: 190-290/290
Sequence Identity: 29% (32 aa)

APEVLRGSLTVSQ--MDPSADVFSFAIIASEILTRKEAWDLKERKEGYDEIIYRVKKGGSFPIRPDIITDVPDVNPT------LIALVKDCWAEAPEDRP
.|| .| ..  .   ..|  || ||||.  |.||.|..    | .. .  |....|.|     ||. ...||.  |.      .| | ..||. .|.|||
PPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPY---EDRKCMMMIMMCCKQG----HRPC-LQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRP

TAENICEQL
.   . |. 
CFQECEEWT
S_TKc gcy-3.AA S_TKc 563-826 15 1.4e-11 -6.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 563-826
Range on HMM: 1-231/231
Sequence Identity: 15% (43 aa)

ITGESKVSTGSEFCENYEVKMFEKDMVLTMKFQYMNLNKADMDKFVKLRKLDHENLNKFIGLSIDSSQFISVTKLCSR--GSLLDILYKGNFS-----MD
 .   |.  |. | . | ..  . . .  .|      ...     .  .  .|.|. |...   | . .  |. .|.   |.|.|.. | .       ..
YEILRKIGKGA-FGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

FFFMYCIIKDVAEGMSYLHKSFLRLHGNLRSATCLVNDSWQVKLAEFGFDQLLEEITPTKRRLLWAAPEVLRGSLTVSQMDP-SADVFSFAIIASEILTR
     .... ..... |.|.    .|  |  .  |...  ..|.. ||.  .|   |     . . |||||       . .. ..|. |. .|  | |..
E-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCG

KEAWDLKERKEGYDEIIYRVKKGGSFPIRPDIITDVPDVNPTLIALVKDCWAEAPEDRPTAENICE-----QLRDLM
.  ..       ..... ...                   | .. ... |.   ||.||||  . .      .   .
YPPFP------QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase gcy-3.AA Pkinase 720-822 18 4.4e-11 40.28 Pfam 177-293 (293) Show / Hide 
Range on Protein: 720-822
Range on HMM: 177-293/293
Sequence Identity: 18% (22 aa)

WAAPEVLRGSLTVSQMDPSADVFSFAIIASEILTRKEAWD-LKERKEGYDEIIYRVKKGGSFPIRPDIITDVP----------------DVNPTLIALVK
..||||.|   . .  .|..|..|. .|  | |...  ..      .. .. ...... .. |.. |. .. .                 ...... ..|
YMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

DCWAEAPEDRPTAENICEQ--L
.|..  |..||||| |..   .
WCLCKDPKKRPTAEQILQHPWF
Kinase gcy-3.AA Dicty5 739-826 34 6.8e-11 33.72 In-house 184-260 (260) Show / Hide 
Range on Protein: 739-826
Range on HMM: 184-260/260
Sequence Identity: 34% (31 aa)

ADVFSFAIIASEILTRKEAWDLKERKEGYDEIIYRVKKGGSFPIRPDIITDVPDVNPTLIA-LVKDCWAEAPEDRPTAENICEQLRDLM
.||.||.|.  |..||||. |   .     .|   | ||.    || |  |.    || |. |.| || . |  ||.   ||. .. ..
CDVYSFGIVLWEMFTRKEPYDNINNW----NIPVMVMKGE----RPTIPKDC----PTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase gcy-3.AA DRK 610-703 34 2.6e-10 31.14 In-house 51-145 (258) Show / Hide 
Range on Protein: 610-703
Range on HMM: 51-145/258
Sequence Identity: 34% (33 aa)

LRKLDHENLNKFIGLSIDSSQFISVTKLCSRGSLLDILYKGNFSMDFFFMYCIIKDVAEGMSYLHKSF-LRLHGNLRSATCLVNDSWQVKLAEFG
. .| | |   |.|    ..    ..   .||||  ||     .||   |  .  |.| || ||| .    .|  | |   || ..|||| | ||
MCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFG
TyrKc gcy-3.AA TyrKc 563-822 22 3.2e-10 -57.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 563-822
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

ITGESKVSTGSEFCENYEVKMFEKDMVL--TMKFQYMNLNKADMDKFVK----LRKL--DHENLNKFIGLSIDS-------SQFISVTKLCSRGSLLDIL
|| . |   | .|.| |. ..    .|   ..|          .  | .    ..||  .|.|. ...|  ...        .   |. ... |.|.| |
ITLGKKLGEG-AFGEVYKGTWK--IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-YKGNFSMDFFFMYCIIKDVAEGMSYLHKSFLRLHGNLRSATCLVNDSWQVKLAEFGFDQLLEEI------TPTKRR----LL-------WAAPEVLRGS
 ....       .  .  ..|.||.|||.  .  |  |    |||..  .|| . ||    ...       . ..|              | |||..   
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---

LTVSQMDPSADVFSFAIIASEILTRKEAWDLKERK--EGYDEIIYRVKKGGSFPIRPDIITDVPDV-----NPTLIALVKDCWAEAPEDRPTAENICEQL
   .   .  ||.|| .   ||.|. .     . .     .|.| .||.|.  |. |..    | .      . .  . |.||.| |||||| ..|.|..
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase gcy-3.AA MLK 720-822 24 1.3e-09 29.68 In-house 199-291 (291) Show / Hide 
Range on Protein: 720-822
Range on HMM: 199-291/291
Sequence Identity: 24% (26 aa)

WAAPEVL-RGSLTVSQMDPSADVFSFAIIASEILTRKEAWDLKERKEGYD---EIIYRVKKGGSFPIRPDIITDVPDVNPTLIALVKDCWAEAPEDRPTA
| ||||. .  .  .. . ..||.|....  |.|||..  .     ..||    ... . .|   ||...        .. .  | |.|| . |..||. 
WMAPEVIQQ--FRCEKYSEKCDVWSWGVVLWEMLTREVPYK-----QHYDPMAIAWWVAYNGLRPPIPST-------CPEHWKKLMKQCWNQDPHKRPSF

ENICEQL
  | ..|
RQIVQHL
Kinase gcy-3.AA MLK 609-675 24 7e-08 23.56 In-house 58-142 (291) Show / Hide 
Range on Protein: 609-675
Range on HMM: 58-142/291
Sequence Identity: 24% (21 aa)

KLRKLDHEN----LNKFIGLSIDS-SQFISVTKLCSRGSLLDILYKGN-------------FSMDFFFMYCIIKDVAEGMSYLHK
.||.|.|.|      .| | .... ..|  |.  |. ||| ..|. ..             . .|. ..  . ...|.||.|||.
HLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS
Kinase gcy-3.AA Dicty5 614-703 27 7.9e-07 19.53 In-house 56-149 (260) Show / Hide 
Range on Protein: 614-703
Range on HMM: 56-149/260
Sequence Identity: 27% (26 aa)

DHENLNKFIGLSIDSSQF-ISVTKLCSRGSLLDILYKGNF----SMDFFFMYCIIKDVAEGMSYLHKSFLRLHGNLRSATCLVNDSWQVKLAEFG
|| |. .. |           || .|..||| . |          . .|    .  |.| .| .|| |    |  | |   |..  |..|.  ||
DHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLH-SMNIIHRDLKSMNFLITENWKIKIIDFG
Kinase gcy-3.AA DRK 791-824 35 3e-06 17.07 In-house 225-258 (258) Show / Hide 
Range on Protein: 791-824
Range on HMM: 225-258/258
Sequence Identity: 35% (12 aa)

PDVNPTLIALVKDCWAEAPEDRPTAENICEQLRD
. . |  |.| .||| | |  ||. . . | |  
QWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase gcy-3.AA Dicty4 791-824 27 5e-06 16.27 In-house 242-277 (277) Show / Hide 
Range on Protein: 791-824
Range on HMM: 242-277/277
Sequence Identity: 27% (10 aa)

PDVNPTLIALVKDCWAEAPEDRPTAENICEQ--LRD
... | ...|...|| . |. ||. | | ..  |  
DWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase gcy-3.AA Pkinase_Tyr 802-822 61 8e-06 20.27 Pfam 250-270 (270) Show / Hide 
Range on Protein: 802-822
Range on HMM: 250-270/270
Sequence Identity: 61% (13 aa)

KDCWAEAPEDRPTAENICEQL
|.||.. |||||| . | |||
KQCWHYDPEDRPTFSEIHEQL
Kinase gcy-3.AA TKL-Unique 800-822 34 8e-05 13.15 In-house 268-290 (290) Show / Hide 
Range on Protein: 800-822
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LVKDCWAEAPEDRPTAENICEQL
| ..||.  |..||. ..| . |
LIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-3.AA Pkinase_Tyr 610-703 24 8.4e-05 16.89 Pfam 57-156 (270) Show / Hide 
Range on Protein: 610-703
Range on HMM: 57-156/270
Sequence Identity: 24% (25 aa)

LRKL-DHENLNKFIGLSI-DSSQ--FISVTKLCSRGSLLDILYKG---NFSMDFFFMYCIIKDVAEGMSYLHKSFLRLHGNLRSATCLVNDSWQVKLAEF
...| .|.|. ...|  . .. .   . |. ..  |.||| | |    . . .   . ..  ..|.||.||.   .  |  |.   |||... .|| . |
MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNC-IHRDLAARNCLVTENNVVKICDF

G
|
G
Kinase gcy-3.AA DRK 720-755 47 0.000203 10.92 In-house 168-199 (258) Show / Hide 
Range on Protein: 720-755
Range on HMM: 168-199/258
Sequence Identity: 47% (17 aa)

WAAPEVLRGSLTVSQMDPSADVFSFAIIASEILTRK
| ||||||           |||.||||.  |..||.
WTAPEVLR----NQRYTEKADVYSFAIVLWECVTRQ
Kinase gcy-3.AA Pkinase 610-675 19 0.006347 11.42 Pfam 54-126 (293) Show / Hide 
Range on Protein: 610-675
Range on HMM: 54-126/293
Sequence Identity: 19% (14 aa)

LRKLDHENLNKFIGLSIDSSQFISVTKLCSRG----SLLDILY---KGNFSMDFFFMYCIIKDVAEGMSYLHK
...|.|.|  ....   |..    |. .|  |    .| |..    .|.|...     .... ...|. |.|.
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS
Kinase gcy-3.AA RIPK 662-674 46 0.158486 0.93 In-house 112-124 (290) Show / Hide 
Range on Protein: 662-674
Range on HMM: 112-124/290
Sequence Identity: 46% (6 aa)

IIKDVAEGMSYLH
.|. ...|| |||
MIHEISCGMCYLH
CYCc gcy-3.AA CYCc 861-1057 43 6e-101 342.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 861-1057
Range on HMM: 1-231/231
Sequence Identity: 43% (100 aa)

LEKKKADLLLSRMLPKQVAERLKAGQ-TVEPEGFDSVTVFFSDVVKFTILASKCTPFQVVNLLNDLYSNFDTIIEEHG-----VYKVESIGDGYLCVSGL
 ||.|.| || .|||. ||..||.|. .|.|. .|.||. |.|.| || |.|.|||.||||.|||.|..||.||..||     .|||| |||.| .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PTRNG-------------------FNHIKQIVDMSLKFMDYCKNFKIPHL----PRERVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGK
||||.                    .|...|.|..|. .. .|.|...|     | . . .|||...||.|.||||. |||||.||||||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PSLIHLTSDAHLLL-----MKHFPHQYETNS
|  ||........|     ... ..|.|.  
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-3.AA Guanylate_cyc 888-1076 42 6.4e-97 333.09 Pfam 1-214 (214) Show / Hide 
Range on Protein: 888-1076
Range on HMM: 1-214/214
Sequence Identity: 42% (90 aa)

VEPEGFDSVTVFFSDVVKFTILASKCT----PFQVVNLLNDLYSNFDTIIEEH--GVYKVESIGDGYLCVSGLPTR-----NGFNHIKQIVDMSLKFMDY
|... .|.||..|.|.| || ..|.|.    |.|.|..|||.|..||.....|  |.|||. ||| |.|||||| .     ..  |. ...||.|..|.|
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

CKNFKIPHLPRER-----VELRIGVNSGPCVAGVVG--LSMPRYCLFGDTVNTASRMESNGKPS--LIHLTSDAHLLLMKHFPHQYET--NSRGEVIIKG
|. . ..|..||.     ...|||...||.||||.|  ..|||||..|||||.||||||.|.|.   ||..  .. .|..|.. |.|.   .|||. .||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGV---METFWVLG
||    |||... |
KGKMGEMETYFLHG
HNOBA gcy-3.AA HNOBA 853-882 56 2e-06 24.63 Pfam 205-234 (234) Show / Hide 
Range on Protein: 853-882
Range on HMM: 205-234/234
Sequence Identity: 56% (17 aa)

EERTKELTLEKKKADLLLSRMLPKQVAERL
|. ..||  |||| | ||  |.||.||.||
EQMHRELEEEKKKTDDLLYSMFPKSVANRL