Gene gcy-20 (Nematode worm)

gcy-20

Species: Nematode worm
Alias: aSWK294, CE28919, gcy-20, F21H7.9
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: n/a, WormBase Physical Map location: V: 16256378-16251174,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-20.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 254 Kinase domain by global Sugen HMM Fasta, JSON
gcy-20.AA Protein Genbank 1108 None Fasta, JSON

Protein domain

Protein domains of gcy-20.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-20.AA ANF_receptor 42-420 16 2.7e-45 160.94 Pfam 1-364 (364) Show / Hide 
Range on Protein: 42-420
Range on HMM: 1-364/364
Sequence Identity: 16% (66 aa)

TSAAAVLVAKDRIRAEHLLDQYDFNFTIKFDEC----SESLAAGKVVELLTHDNVDVIIGPTCNRAGVAVASLADFYNVPVFQWGLTTTADIGN--FSRY
  |.|.  | ..| |.. .   ........|.|        |.. ...... ..|..||||.|  .  .||..|. .|.|...||  |     .   .||
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWG-CTCPCLTDKAKNRY

QTTVTLSLDTHSI-SLAVREILRQ-YGWSEFVFIYSNDGDEEKCAAM---KDDMEKMGIENSDVTMAY----MIQIQTVTMESLQRTLLE-VSKRGRIII
.... .  .  .  . |. .|..  .|| ....||..|  . ..  .    .....   |. .   .|    | . ..  .... . . . .....|.|.
PYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYY-YWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIV

ACFASGRG--FKKAFIASTVLAGMSTEEYLYVFAEPQSRGFYVDEADGKVHYSWDDTDGQLVTGLTNEQIRDAYGKVLYICDNMGEPTTITTQYTNFTSQ
 |. . ..  ......   . .|| ...| ...... . .....                  .  . .. ....  .  . . |  . . .. . .|...
MCCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W---------------WYDDDMDNDKFREAMKGVLGFTM--H-P-SPEFQEFMQR

VISRMAEQPFNCVQDCSNQSYKHAATYAGQLADSFYAYAFALNKSLTQDPTRSNLK------NGSFVLSNI-G-MTFQGVGGEAVTLDESGSRIVQVYMF
.                  .     .||... |..|.|| ||.. |..|| ..| .      .|. .|. .   ..|.|| |. |..|..| | .. .. 
WKK----------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGD-VQFDDNGGRRPDYMYW

AMNSS
.||  
IMNWD
Kinase gcy-20.AA RGC 564-803 35 8.70000000001e-130 437.48 In-house 1-300 (300) Show / Hide 
Range on Protein: 564-803
Range on HMM: 1-300/300
Sequence Identity: 35% (106 aa)

HQEVVAAKKHDLLVLFDANQK--SEFRQ---MRNFDNDNLNKFIGLCLDGP------QLLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYF
 ...|..|||   .||..     |..|.   ||. ..||||||||.|.|.|      .....|..|||||| |........||..|..|.|||| .|...
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

IHSSFLKCHGQLTSRCCLIDDRWQIKISGFGLK----------------------SVR-TFENPKKEDLLWASPEYLRNEDQERLPE-----------GD
.|.|....|| |.|..|..|.||..||..|||.                      ..|   |.|.....|| .|| ||...  .  .           ||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFGIICAEILTRSSAFDLE-----------NRKEKPDVIIYQVKKGGHNPTRPSLDTGET---VVINPALLHLVRDCWTERPSERPS-IEQVRSHLNG
.||||||. ||.||....|||           ...|... ..|..||||..|.|||....|.   . .||.||||.||||.|.|.|||. ..|.|..|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-20.AA RGC 564-803 35 8.70000000001e-130 437.48 In-house 1-300 (300) Show / Hide 
Range on Protein: 564-803
Range on HMM: 1-300/300
Sequence Identity: 35% (106 aa)

HQEVVAAKKHDLLVLFDANQK--SEFRQ---MRNFDNDNLNKFIGLCLDGP------QLLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYF
 ...|..|||   .||..     |..|.   ||. ..||||||||.|.|.|      .....|..|||||| |........||..|..|.|||| .|...
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

IHSSFLKCHGQLTSRCCLIDDRWQIKISGFGLK----------------------SVR-TFENPKKEDLLWASPEYLRNEDQERLPE-----------GD
.|.|....|| |.|..|..|.||..||..|||.                      ..|   |.|.....|| .|| ||...  .  .           ||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFGIICAEILTRSSAFDLE-----------NRKEKPDVIIYQVKKGGHNPTRPSLDTGET---VVINPALLHLVRDCWTERPSERPS-IEQVRSHLNG
.||||||. ||.||....|||           ...|... ..|..||||..|.|||....|.   . .||.||||.||||.|.|.|||. ..|.|..|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-20.AA TKL 562-801 17 1.1e-26 93.05 In-house 13-364 (364) Show / Hide 
Range on Protein: 562-801
Range on HMM: 13-364/364
Sequence Identity: 17% (63 aa)

HYHQ----------EVVAAKKHDLLVL----------------------------FDANQKSEFRQMRNFDNDNLNKFIGLCLDGPQ-------------
....          ..|| ||                                  |    . | ..|.... .|. .|.| |...|.             
KWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQ

LLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYFIHSSFL-------KCHGQLTSRCCLIDDRWQ--------------IKISGFGLKSVRT
|     .|..||| ...           ......||. |... ||.           |  |.|. .|.|. |.              .||. |||  . .
LCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMS

-----------------------FENPKKEDLLWASPEYLRNEDQERLPEG--------------DIYSFGIICAEILTRSSAFD-LENRKEKPD----V
                         ...   . | .|| ||.... .   |              |.|||||.  |||||   .. . .. ...      
QSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEE

IIYQVKKGGHNPTRP-----SLDTGETVVINPA---LLHLVRDCWTERPSERPSIEQVRSHL
....| . |. |..|      .     .  ...   .  |  ||| . |..||| ... ..|
MFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-20.AA TKL-Unique 584-732 24 1.2e-20 69.61 In-house 43-224 (290) Show / Hide 
Range on Protein: 584-732
Range on HMM: 43-224/290
Sequence Identity: 24% (45 aa)

KSEFRQMRNFD-NDNLNKFIGLCL----DGPQLLSLWRFCSRGSLSDVIS---------KSSMQMDSFFMFSLIRDISNGLYFIHSSFL-KCHGQLTSRC
..| . | ...  .|. ...| |     . |..     .|..||| ||..         .... ..   . ....||. |.|..|..     |. |.|. 
ENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSN

CLIDDR-----WQIKISGFGLKSVRT--FENPKKED-----------LLWASPEYLRNEDQERLPEGDIYSFGIICAEILTR
 |.| .     |.|||..|||  ...   .....|            ..|..|| ||..   .    |.|||||.  ||.||
FLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase gcy-20.AA Pkinase 700-801 17 6.1e-14 50.37 Pfam 177-293 (293) Show / Hide 
Range on Protein: 700-801
Range on HMM: 177-293/293
Sequence Identity: 17% (21 aa)

WASPEYLRNEDQERLPEGDIYSFGIICAEILTRSSAFDLEN----RKEKPDVIIYQVKKGGHNPTRPSLDT-------------GETVVINPALLHLVRD
...|| .| ..|.  |. |..|.|.|..| |..   |. .     .   ....|......     .| ...                . ...........
YMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKW

CWTERPSERPSIEQVRSH--L
|..  |..||..||.  |  .
CLCKDPKKRPTAEQILQHPWF
Kinase gcy-20.AA TK 585-801 12 1.6e-12 37.52 In-house 90-486 (486) Show / Hide 
Range on Protein: 585-801
Range on HMM: 90-486/486
Sequence Identity: 12% (49 aa)

SEFRQMRN--FDNDNLNKFIGLCLDG------------PQLLSLWRFCSRGS----LSDVISKSSM----------------------------------
.|  .|..  .. .|. ...| |..|            . .. .  ... |.    | |   |..                                   
EEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHE

-----------------------------------------QMDSFFMFSLIRDISNGLYFIHSSFLK-----CHGQLTSRCCLIDDRWQ----------
                                         |..   .    ..|..|. ..||   .      |. |  | ||.... .          
SNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGP

-IKISGFGLK------SVRTFEN--------------------------------PKKEDLLWASPEYLRNEDQERL-------PEGDIYSFGIICAEIL
 .||. |||         |  ..                                  |  . | .|| |.     .        .. |..|||. . ||.
VCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIF

T---RSSAFDLENRK----EKPDVIIYQVKKGGHNP-----------TRPS--LDTGE-------TVVINPALLHL-VRDCWTERPSERPSIEQVRSHL
|      . .. |..    . ..  ...  . |. .            |.    .  .       .   .|.....  ..|| . |..||. .|... |
TYGQEPYYGGMSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-20.AA RAF 661-801 20 4.1e-11 34.3 In-house 123-275 (275) Show / Hide 
Range on Protein: 661-801
Range on HMM: 123-275/275
Sequence Identity: 20% (34 aa)

HGQLTSRCCLIDDRWQIKISGFGLKSVRTFENP---------KKEDLLWASPEYLRNE------DQ-ERLP---EGDIYSFGIICAEILTRSSAFDLENR
|. | |.. ....   ..|  ||| .|   ...          .  ..| .|| .|.       .| . .|   . | |.||..  |.....  .  .. 
HRDLKSKNIFLHNGKVVVITDFGLFTVKRCRWCKRRKQQLCQPHGWICWMAPEVIRMMRPDWDEYQCDCNPFSFQSDVYAFGTVWYELMAGEWPYQHIQW

KEKPDVIIYQVKKGGHNPTRP--SLDTGETVVINPALLHLVRDCWTERPSERPSIEQVRSHL
.|.   ||..| .|   . |.  .....       ..  |. .||.  | ||||  |. . .
HEQ---IIWMVCRGYLRMDRSKARVQCPK------EMKELLMECWSYQPEERPSFQQIMKMI
S_TKc gcy-20.AA S_TKc 542-801 16 3.3e-10 -27.3 SMART 11-231 (231) Show / Hide 
Range on Protein: 542-801
Range on HMM: 11-231/231
Sequence Identity: 16% (45 aa)

STSTKMTVESRTETTNFIFYHYHQEVVAAKKHDLLVLFDANQKSEFRQMRNFDNDNLNKFIGLCLDGPQLLSLWRFCSR--GSLSDVISKSSMQ-----M
. .. . .  .            ...|| |. .       . ..| . ... . .|. |... . |   |     .|.   |.| |.| |   .     .
AFGKVYKCRHKK----------TGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DSFFMFSLIRDISNGLYFIHSSFLKCHGQLTSRCCLIDDRWQIKISGFGLKSVRTFENPKKEDLL----WASPEYLRNEDQERLP-EGDIYSFGIICAEI
.     .... | ..| ..||    .|  |     |.|.  .|||. |||  .          .     . .|| |        . . |..|.|.| .| 
PE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEM

LTRSSAFDLENRKEKPDVIIYQVKKGGHNPTRPSLDTGETVVINPALLHLVRDCWTERPSERPSIEQVRS-------H--L
|..   |.        .  .... .                   | .....| |..  |..||.. ..         |  .
LCGYPPFP-------QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc gcy-20.AA TyrKc 518-801 17 4.3e-10 -59.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 518-801
Range on HMM: 1-280/280
Sequence Identity: 17% (58 aa)

FVELQQVQS-------KSRAEASMHSFASGPSTSTKMTVESRTETTNFIFYHYHQEVVAAKKHDLLVLFDANQKSEFRQMRNF--DNDNLNKFIGLCLDG
 . ...  .       | ..                                   . || |.        .   .| | |...  ...|. ...| |...
ITLGKKLGEGAFGEVYKGTWK----------------------------------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQ

-------PQLLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYFIHSSFLKCHGQLTSRCCLIDDRWQIKISGFGLKSVRTFEN---------
       ..|. .  ... |.| | . |.  .     . |   .|..|  ..||  .  |  |  | ||.... ..||| ||| |    .          
GRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGL-SRDIYDDDQQGESKDY

-PKKE--DLL------WASPEYLRNEDQERL--PEGDIYSFGIICAEILTRSSAFDLE---NRKEKPDVIIYQVKKGGHNPTRPS-----LDTGETVVIN
  |||  .        | .|| .    ...   .. |..|||. . ||.|.      .   . . ... .| .||.|.  |  |.           |   
YRKKEHKGGKTMLPIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCP

PALLHLVRDCWTERPSERPSIEQVRSHL
...  . ..|| | |..||. ..... .
DEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase gcy-20.AA TK-Unique 600-731 16 1e-09 29.78 In-house 68-234 (294) Show / Hide 
Range on Protein: 600-731
Range on HMM: 68-234/294
Sequence Identity: 16% (28 aa)

KFIGLCLDGP-QLLSLWRFCSRGSLSDVISKSSMQ-------------------------MDSFFMFSLIRDISNGLYFIHSSFLK--CHGQLTSRCCLI
...| | .   . . .. .|..|.| . . .. ..                          ....... . .| .|. ...|  .|   |..| .| .|.
QCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLAS-QRKKIVHRDLCARNVLL

DDRWQIKISGFGLKS-------VRTFENPKKEDLLWASPEYLRNEDQER-LPEGDIYSFGIICAEILT
 .. ..||..||.         . . .  ..  . | .||.|.  ..    ...|..|||..  ||.|
TEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase gcy-20.AA RAF 661-803 27 1.9e-09 26.48 In-house 126-282 (282) Show / Hide 
Range on Protein: 661-803
Range on HMM: 126-282/282
Sequence Identity: 27% (45 aa)

HGQLTSRCCLIDDRWQIKISGFGLKSVRTFENPKKED--------LLWASPEYLR---------NEDQERLP---EGDIYSFGIICAEILTRSSAF--DL
|  | |.  . ..  ..||  |||  |.| ..|. .          || .||  |            |...|   . |.|||||.  |..||.  .  . 
HRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVYSFGIVMYELMTRHMPYGCHI

ENRKEKPDVIIYQVKKGGHNPTRPSLDTGETVVINPALLHLVRDCWTERPSERPSIEQVRSHLNG
.||    | ||. .   |    || |.      .  |.  |. |||  .. |||. .|. . .. 
WNR----DQIIFMC---GRGYLRPDLSK-VRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase gcy-20.AA UTK 775-801 29 2.6e-07 21.05 In-house 270-296 (296) Show / Hide 
Range on Protein: 775-801
Range on HMM: 270-296/296
Sequence Identity: 29% (8 aa)

ALLHLVRDCWTERPSERPSIEQVRSHL
..  |...||.  |.|||..|.... .
PVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase gcy-20.AA TKL-Unique 772-801 30 3e-06 18.09 In-house 261-290 (290) Show / Hide 
Range on Protein: 772-801
Range on HMM: 261-290/290
Sequence Identity: 30% (9 aa)

INPALLHLVRDCWTERPSERPSIEQVRSHL
... . .| ..||.  ||.||| ..... |
CPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-20.AA TK-Unique 783-801 47 3e-06 17.81 In-house 276-294 (294) Show / Hide 
Range on Protein: 783-801
Range on HMM: 276-294/294
Sequence Identity: 47% (9 aa)

CWTERPSERPSIEQVRSHL
||.. |.||||..|... |
CWQWEPEERPSFRQIKHRL
Kinase gcy-20.AA UTK 590-684 18 4e-06 17.14 In-house 63-174 (296) Show / Hide 
Range on Protein: 590-684
Range on HMM: 63-174/296
Sequence Identity: 18% (21 aa)

MRNFD-NDNLNKFIGLCLDGPQLLSLWRFCSRGSLSDVISKSSMQMD-SFFMFS------LIRDISNGLYFIHSSFLKCHGQLTSRCCLIDDR-------
| .|.   |. ...|.|... ... .......|.|...  ... . .   ....        .||..|. ..||  .  |. |  | ||...        
MKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGF-VHRDLAARNCLVHMHRMMWHCM

WQIKISGFG---L
...||..||   .
MVCKIADFGRGGM
Kinase gcy-20.AA DRK 779-803 40 3.2e-05 13.69 In-house 234-258 (258) Show / Hide 
Range on Protein: 779-803
Range on HMM: 234-258/258
Sequence Identity: 40% (10 aa)

LVRDCWTERPSERPSIEQVRSHLNG
|  ||| | |. ||| ...   |  
LMNDCWNEDPQHRPSMQECLERLEA
Kinase gcy-20.AA DRK 601-684 30 0.000187 11.04 In-house 62-146 (258) Show / Hide 
Range on Protein: 601-684
Range on HMM: 62-146/258
Sequence Identity: 30% (26 aa)

FIGLCLDGPQLLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYFIHSSF-LKCHGQLTSRCCLIDDRWQIKISGFGL
|.| |.  |  .    . .||||  .    |..||   | ..  |.  |. . |..     |  | |   |.|. ||.|.. |||
FMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL
Kinase gcy-20.AA Pkinase_Tyr 781-801 28 0.000359 14.75 Pfam 250-270 (270) Show / Hide 
Range on Protein: 781-801
Range on HMM: 250-270/270
Sequence Identity: 28% (6 aa)

RDCWTERPSERPSIEQVRSHL
..|| . |..||. ......|
KQCWHYDPEDRPTFSEIHEQL
Kinase gcy-20.AA DRK 700-732 47 0.001105 8.39 In-house 168-198 (258) Show / Hide 
Range on Protein: 700-732
Range on HMM: 168-198/258
Sequence Identity: 47% (16 aa)

WASPEYLRNEDQERLPE-GDIYSFGIICAEILTR
| .|| |||   .|  |  |.|||.|.  |..||
WTAPEVLRN---QRYTEKADVYSFAIVLWECVTR
Kinase gcy-20.AA UTK 718-732 53 0.24772 0.32 In-house 222-236 (296) Show / Hide 
Range on Protein: 718-732
Range on HMM: 222-236/296
Sequence Identity: 53% (8 aa)

DIYSFGIICAEILTR
|..|||. | ||.|.
DVWSFGVVCWEIWTW
CYCc gcy-20.AA CYCc 840-1035 45 6.1e-97 329.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 840-1035
Range on HMM: 1-231/231
Sequence Identity: 45% (104 aa)

EEKKKSDVLLYRMLPRMVADKLKLGQ-TVEPETFEQVTIFFSDVVQFTTLAGKCTPLQVVTLLNDLYTIFDGIIEQND-----VYKVETIGDGYLCVSGL
.||.| | ||..||||.||. || |. .|.|.... ||| |.|.| ||.|. .|||.|||..|||.|| || ||....     .||||||||.| .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PHRNG-------------------NDHIRHIARMSLGFLSSLEFFRVQHL----PAERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGK
|.||.                    .|.. || ..|. ..... | |||     | . ...||||..|.||.||||..|||||.|||.||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PGQIHVTAEANRML------TQVVGGFRTES
||||||. |. . |      ..  |.|..| 
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-20.AA Guanylate_cyc 867-1054 42 2.6e-88 304.5 Pfam 1-214 (214) Show / Hide 
Range on Protein: 867-1054
Range on HMM: 1-214/214
Sequence Identity: 42% (91 aa)

VEPETFEQVTIFFSDVVQFTTLAGKCT----PLQVVTLLNDLYTIFDGIIEQN--DVYKVETIGDGYLCVSGLPHR-----NGNDHIRHIARMSLGFLSS
|... ...|||.|.|.| || .. .|.    |.|.|..|||.|| || ...|.  ..|||.|||| |.|||||| .     .. .|.. .| |.|... .
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

LEFFRVQHLPAER-----INLRIGINCGSVVAGVVG--LTMPRYCLFGDAVNTASRMESNGKPG--QIHVTAEANRMLTQVVG-GFRT--ESRGEVIIKG
.. ..|.|.. |.     |..||||..|.|||||.|  . |||||..|| ||.||||||.|.||  .|||..|. | |..  .  |..  ..|||. .||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGV---METFWLLG
||    |||..| |
KGKMGEMETYFLHG
HNOBA gcy-20.AA HNOBA 835-861 59 4.2e-08 30.87 Pfam 208-234 (234) Show / Hide 
Range on Protein: 835-861
Range on HMM: 208-234/234
Sequence Identity: 59% (16 aa)

TKELTEEKKKSDVLLYRMLPRMVADKL
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HRELEEEKKKTDDLLYSMFPKSVANRL