Gene gcy-18 (Nematode worm)

gcy-18

Species: Nematode worm
Alias: gcy-18, gcy-26, aSWK288, CE15463, ZK896.8
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 12860112-12865910, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-18.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 279 Kinase domain by global Sugen HMM Fasta, JSON
gcy-18.AA Protein Genbank 1112 None Fasta, JSON

Protein domain

Protein domains of gcy-18.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-18.AA ANF_receptor 66-432 19 4.1e-65 227.44 Pfam 1-364 (364) Show / Hide 
Range on Protein: 66-432
Range on HMM: 1-364/364
Sequence Identity: 19% (76 aa)

NDARILNISKENLIEEGL-VGDDIEFEIVSRQAC--SESFEGVAVAAELYHVHQVRAFIGPYCAAELEAVTKMATFWNIPIISYSSVPNAVSD--RSVYK
. |. ...  | .  ..   . .|.....  . |  |..  .||.|....| ..| |.|||.| .. ..| ..|. ||||.||...   ...|  .. |.
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWGCTCPCLTDKAKNRYP

TLARVSSKNTNSIAEATVALLLH-YKWLKVAIATNTGST--AFER---VSIFEEIMHREGVTIVKK--VMFDENTDANEMMNSGQLGD-LAANARIIICL
...|.    |. ...| |... | ..| .||.  . ..     .    ...|.......|...| .  |.. . .| ..|  . .. | .. .||.|.. 
YFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIVMC

FSSTKE--LSKEFMQATYTMRMNNAEYAYIIPWLQSGTKDLTPWIGADGEMLQRVKDHYANAIIVDDVNGFDDSVVSSFVEKIEKHGMQKSDIDTNINGY
....    |....||. . ..|.. .|..|  .. ... | . | ..|..|..    ......... .  . .. .. |.... |        || .|.|
CYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W-WYDDDMDNDKFREAMKGVLGFTMH-P-SPEFQEFMQRWKK-------TDTEMNYY

-LHLFDSLKLYALAIRKVLNETDNEAYVT------NGQFIWNRMRR-MKFEGVVSRSSSEENKDAGAIGTVLMDDVADRAPIFSAFYISPN
 ....|. .||| |....|... |    .      .|. . ..|.  ..|               |. |.| .||  .| | ..  .. ..
AAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNF--------------EGVTGDVQFDDNGGRRPDYMYWIMNWD
Kinase gcy-18.AA RGC 575-845 33 8.99999999999e-125 420.82 In-house 1-300 (300) Show / Hide 
Range on Protein: 575-845
Range on HMM: 1-300/300
Sequence Identity: 33% (102 aa)

VNTHTTYHRYKQR---RPIKFIKEDMQLLTQMKQAVHDNLNPFLGAAFNEKEE-----MLVLWKFCSRGTIQDIIYNANVVLDEKFHGAFVRDITLGLEY
 ...  .....||   |...| ...|..| ||.|..|||||.|.|. .....|     |...|..||||..|||..| .. .|..|...|.|||. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHASPIGYHGSLTPWCCLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAAKDSDDKSQASQATSIIYMAPELLKNRETNKRRGMDQSWV--KQSMLRRQA
||.|||.|||.|..|.|..|..|.||..|.|..|||..|.|.|.|... .| |||||. .| .. .|....| .. | .....|...|   .|.....|.
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPP-CK-SDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQK

GDIYSFGMVMYEILFRSLPFRDNTN-------ISELVDYLAD--------GSKTVSPEIQNQMG-----LHPDLNALLRDCWSENPEIRPS-IRRVRLNT
||.||||..||||..|. |.. ...        ... ... .        |.|.  |.|.....     ..|.| .|.||||.|.|| ||. ....|.. 
GDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQL

EM
..
KT
Kinase gcy-18.AA RGC 575-845 33 8.99999999999e-125 420.82 In-house 1-300 (300) Show / Hide 
Range on Protein: 575-845
Range on HMM: 1-300/300
Sequence Identity: 33% (102 aa)

VNTHTTYHRYKQR---RPIKFIKEDMQLLTQMKQAVHDNLNPFLGAAFNEKEE-----MLVLWKFCSRGTIQDIIYNANVVLDEKFHGAFVRDITLGLEY
 ...  .....||   |...| ...|..| ||.|..|||||.|.|. .....|     |...|..||||..|||..| .. .|..|...|.|||. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHASPIGYHGSLTPWCCLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAAKDSDDKSQASQATSIIYMAPELLKNRETNKRRGMDQSWV--KQSMLRRQA
||.|||.|||.|..|.|..|..|.||..|.|..|||..|.|.|.|... .| |||||. .| .. .|....| .. | .....|...|   .|.....|.
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPP-CK-SDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQK

GDIYSFGMVMYEILFRSLPFRDNTN-------ISELVDYLAD--------GSKTVSPEIQNQMG-----LHPDLNALLRDCWSENPEIRPS-IRRVRLNT
||.||||..||||..|. |.. ...        ... ... .        |.|.  |.|.....     ..|.| .|.||||.|.|| ||. ....|.. 
GDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQL

EM
..
KT
Kinase gcy-18.AA TKL 608-835 20 2.1e-22 77.51 In-house 84-356 (364) Show / Hide 
Range on Protein: 608-835
Range on HMM: 84-356/364
Sequence Identity: 20% (57 aa)

HDNLNPFLGAAFNEKE------------EMLVLWKFCSRGTIQDIIYNANVVLDEKFH--GAFVRDITLGLEYLHA-------SPIGYHGSLTPWCCLID
|.|. .|.|......             ..     .|..|.  ...          .|    ...|| .|..|||.        |   |  |..  .|.|
HPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVD

RNWM--------------VKLSDYGIANPLERWEKQGAIEIAAA-----KDSDDKSQASQATSIIYMAPELLKNR-ETNKRRGMDQSWVKQSMLRRQAGD
.||               .|..|.|..  ... ... ... .       . . .|   .|  .. .||||.|..  ....  |.|.   |..    .. |
ENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKC-D

IYSFGMVMYEILFRSLPFRDNTNISELVDY------LADGSKTVSPEIQNQ-------MGLHPD---LNALLRDCWSENPEIRPS
.||||.|..||| | .|..|. ......          ...|   |.| ..       .  ..    .  |. |||...|| |||
VYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS
Kinase gcy-18.AA TKL-Unique 631-843 22 9.9e-21 69.95 In-house 81-290 (290) Show / Hide 
Range on Protein: 631-843
Range on HMM: 81-290/290
Sequence Identity: 22% (53 aa)

FCSRGTIQDIIY---------NANVVLDEKFHGAFVRDITLGLEYLHASP--IGYHGSLTPWCCLIDRN-----WMVKLSDYGIANPLERWEKQGAIEIA
.|..|.  | .          | |  |. .    ...|| .|..||| .   | .|. |..   |.|.|     | .|..| |..  . .  |  ..|. 
YCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPI-IHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHK

AAKDSDDKSQASQATSIIYMAPELLKNRETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEILFRSL------PFRDNTNI--SELVDYLADGSKTVSP
  .       ..  .|...||||.|.. .                .. .  |.||||.|..||. | .      |... . .   |.|.|  ...    |
GTR------NQTRCGSFRWMAPEVLRMNF---------------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYR---P

EIQNQMGLHPDLNALLRDCWSENPEIRPSIRRVRLNT
.| | .   ...  |...||  .|..|||   ..   
PIPNHC--PKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-18.AA RAF 658-845 23 3.7e-14 42.0 In-house 110-282 (282) Show / Hide 
Range on Protein: 658-845
Range on HMM: 110-282/282
Sequence Identity: 23% (44 aa)

RDITLGLEYLHASPIGYHGSLTPWCCLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAAKDSDDKSQASQATSIIYMAPELLKNRETNKRRGMDQSWVKQ
| . .|..||||  |  |  |     . .    ||  |.| .    ||  .|. ..                .| .||||  .|   . |  .     . 
RQVCQGMDYLHAKNI-IHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQP-----------THWILWMAPEVIRNLMIDWRGDV---LMQD

SMLRRQAGDIYSFGMVMYEILFRSLPFRDNTNISELVDYLADGSKTVSPEIQNQMGLHPD-LNALLRDCWSENPEIRPSIRRVRLNTEM
     .  |.||||.||||.. |..|.  . .  ... ..  | . ..|..  ..   |  .  |. |||. ..| ||. . .    ..
ENPYSFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMC-GRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase gcy-18.AA LRRK 766-835 25 5.5e-12 38.68 In-house 264-341 (351) Show / Hide 
Range on Protein: 766-835
Range on HMM: 264-341/351
Sequence Identity: 25% (20 aa)

DIYSFGMVMYEILFRS-LPFRDNT-N-----ISELVDYLADGSK-TVSPEIQNQMGLHPDLNALLRDCWSENPEIRPS
|.|||||...|.| |. .||.. .       .... |   .| . |........  . ... .|. .||...|. ||.
DCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPH
Kinase gcy-18.AA TAK1 766-835 28 6e-12 36.54 In-house 207-277 (284) Show / Hide 
Range on Protein: 766-835
Range on HMM: 207-277/284
Sequence Identity: 28% (21 aa)

DIYSFGMVMYEILFRSLPFRDNTN---ISELVDYLADGSKTVSPEIQNQMGLHPDLNALLRDCWSENPEIRPS
||||.| .| |.. | .|.... |   . ..    . | .   | . |   . . .  .   ||..|||.|||
DIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRP--PMETNRSDCPKRIEQFMKCCWDDNPEKRPS
S_TKc gcy-18.AA S_TKc 545-846 15 6.5e-11 -16.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 545-846
Range on HMM: 1-231/231
Sequence Identity: 15% (50 aa)

EQVKSMMSVGSVTTKLSNIQTG-QKQHAIIGVNTHTTYHRYKQRRPIKFIKEDMQLLTQMKQAVHDNLNPFLGAAFNEKEEMLVLWKFCSR--GTIQDII
 ..      |.  .    . .. ... ||  ..              . |.  .|.| .     |.|.  ....  .  ... .   .|.   |.  |.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYI

YNANVV-----LDEKFHGAFVRDITLGLEYLHASPIGYHGSLTPWCCLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAAKDSDDKSQASQATSIIYMAP
 . .       ..|     ... | ..|||.|   |  |  | |   |.|.   .|..| |.|  |                       ..  .  ||||
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL----------------------TTFCGTPWYMAP

ELLKNRETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEILFRSLPFRDNTNISELVDYLADGSKTVSPEIQNQMGLHPDLNALLRDCWSENPEIRPSI
|.|                      . . |..|.| ..|| | .  ||.   .. .. . .                  |..  ..| |.  .|| ||..
EVL-------------------GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA

RRVRL------NTEMV
  .        . . .
-EALQDEWDIKCHPWF
Kinase gcy-18.AA RAF 730-843 22 9.1e-11 33.11 In-house 168-275 (275) Show / Hide 
Range on Protein: 730-843
Range on HMM: 168-275/275
Sequence Identity: 22% (26 aa)

SIIYMAPELLKNR--ETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEILFRSLPFRDNTNISELVDYLADGSKTVSPEIQNQMGLHPDLNALLRDCWS
.| .||||.. .   .. . ....    .||       | |.|| |.||.. ...|.  ...  | . .   . . . .  ...  .  ..  || .|||
WICWMAPEVIRMMRPDWDEYQCDCNPFSFQS-------DVYAFGTVWYELMAGEWPYQ-HIQWHEQIIWMVCRGYLRMDRSKARVQCPKEMKELLMECWS

ENPEIRPSIRRVRLNT
 .|| ||| ...    
YQPEERPSFQQIMKMI
Kinase gcy-18.AA MLK 726-835 19 4.4e-10 31.29 In-house 192-283 (291) Show / Hide 
Range on Protein: 726-835
Range on HMM: 192-283/291
Sequence Identity: 19% (22 aa)

SQATSIIYMAPELLKNRETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEILFRSLPFR-DNTNISELVDYLADGSK-TVSPEIQNQMGLHPDLNALLR
|.| . ..|||| ..               ...     . |..|.|.|..|.| | .|.. .. ..  .    . |   .. ..        . .. |. 
SNAGTYAWMAPEVIQQ--------------FRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST------CPEHWKKLMK

DCWSENPEIRPS
.||...|. |||
QCWNQDPHKRPS
Kinase gcy-18.AA RIPK 766-843 25 6.8e-10 29.86 In-house 210-290 (290) Show / Hide 
Range on Protein: 766-843
Range on HMM: 210-290/290
Sequence Identity: 25% (21 aa)

DIYSFGMVMYEILFRSLPFRDNTNISELVDYLADGSKTVSPEIQNQMGLHPD------LNALLRDCWSENPEIRPSIRRVRLNT
|.|||..||.|.| .  |. | ...  ..  .. |.    |..|      |       .  |...||. .|. ||. . ..  |
DVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGH---RPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase gcy-18.AA Pkinase 683-846 13 7.3e-08 28.88 Pfam 139-293 (293) Show / Hide 
Range on Protein: 683-846
Range on HMM: 139-293/293
Sequence Identity: 13% (26 aa)

CLIDRNWMV----KLSDYGIANPLERWEKQGAIEIAAAKDSDDKSQASQATSIIYMAPELLKNRETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEIL
.|||.|  .    |..| |.|  ..                 .    . . .. |||||...                 .    .. |..|.| ..|| |
ILIDNNGHIDACVKICDFGLAKQFD--------------Y-NNS-MTTFCGTPWYMAPEVIR----------------GGQYYGPKVDMWSCGCILYEML

FRSLPFRDN----TNISELVDYLADGSKTVSPEIQ------------------NQMGLHPDLNALLRDCWSENPEIRPSIRRVRLNTEMV
.. .||..     . ..... .  .... .. ...                  .   .....  ....|.  .|. ||... . |. . .
CGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI-LQHPWF
TyrKc gcy-18.AA TyrKc 557-846 16 3.8e-07 -107.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 557-846
Range on HMM: 1-280/280
Sequence Identity: 16% (57 aa)

TTKLSNIQTGQ------------------KQHAIIGVNTHTTYHRYKQRRPIKFIKEDMQLLTQM--KQAVHDNLNPFLGAAFNEK------EEMLVLWK
 |..  .  |.                  | .|                    |..| ......   .   |.|.  ..|..  ..      | ....  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----------------REDFMRE-ARIMCKLGGH---HPNIVRLYGVCTQQGRNFMYIEPLMIVME

FCSRGTIQDII-YNANVVLDEKFHGAFVRDITLGLEYLHASPIGYHGSLTPWC---------CLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAAKDSD
... |  .| . .. . .  ....  |  .|  | ||||             |         ||...|  || || | .  ..   .||     ..||  
YMPHGDLKDYLRKHRPKLCMKDLL-SFCWQIACGMEYLHSK----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----ESKDYY

DKSQASQAT--SII-YMAPELLKNRETNKRRGMDQSWVKQSMLRRQAGDIYSFGMVMYEILFRSLPFRDN-----TNISELVDYLADGSKTVSPEI----
.|.. ...     |  |||| .. .. .                  . |..||| .|.||. .  .   .      . .|.. |. .|     |.     
RKKEHKGGKTMLPIRWMAPECINYGKFT-----------------TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPM

-QNQMGLHPDLNALLRDCWSENPEIRPSIRRVRLNTEMV
     . ....  . ..|| |.|| ||. . .    |  
SF--VCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
CYCc gcy-18.AA CYCc 881-1076 45 5.8e-110 372.54 SMART 1-231 (231) Show / Hide 
Range on Protein: 881-1076
Range on HMM: 1-231/231
Sequence Identity: 45% (105 aa)

EANIRADQLLTQLLPAYVANELKMGR-SVAPKLYSSATILFSDIVGFTTICSGSTPLEVVNMLNGLYTGFDECITRNK-----SYKVETIGDAYMVVSGI
... ..|.||.|.||..|||.|| || .|.|..|...||||.||||||..|| .||..||||||..|| ||..| |..      |||||||||||||||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PEENE-------------------YNHSRNIANTALDMRQYLTGYQIPHR----PTHRVRCRWGFHTGSVAAGVVGLTCPRYCLFGDTVNVSSRMESTGT
|..||                   ..| ..||. ||||.. .......|.    | . .|.|.|.|||.|..||||...||||.||||||. ||||||| 
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PGMIQMSEEAHMHI------RAHHPVFTTTE
|| |..|||.....      | ... |.. .
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-18.AA Guanylate_cyc 908-1095 41 1.8e-70 245.23 Pfam 1-214 (214) Show / Hide 
Range on Protein: 908-1095
Range on HMM: 1-214/214
Sequence Identity: 41% (88 aa)

VAPKLYSSATILFSDIVGFTTICSGST----PLEVVNMLNGLYTGFDECITRN--KSYKVETIGDAYMVVSGIPEE-----NEYNHSRNIANTALDMRQY
| .. | . ||.|.|||||| .|| ..    |...|.||| .|| ||. . ..    |||.||||.||.|||.|..     . . | . .|. |||| .|
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

LTGYQIPHRPTHR-----VRCRWGFHTGSVAAGVVG--LTCPRYCLFGDTVNVSSRMESTGTPG--MIQMSEEAHMHIRAHH-PVFTT--TERGEVQVKG
..  ...| .  .     .. | | |||.| |||.|  .  ||||..|||||| ||||||| ||   |..|||...  ..|  ..|..  ..|||. |||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGT---CRTFWLED
||      |..|. 
KGKMGEMETYFLHG