Gene gcy-15 (Nematode worm)

gcy-15

Species: Nematode worm
Alias: aSWK278, ZC239.7, gcy-15, CE26332
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 3196868-3192413, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-15.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
gcy-15.AA Protein Genbank 1000 None Fasta, JSON

Protein domain

Protein domains of gcy-15.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase gcy-15.AA RGC 454-706 32 1.1e-109 370.75 In-house 1-300 (300) Show / Hide 
Range on Protein: 454-706
Range on HMM: 1-300/300
Sequence Identity: 32% (97 aa)

EGRTVALKRIYRS----DVEFTRSNRLEIAKLQESVNSNVIEFVGMVVQSP------DVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEY
||..|..|.. ..    ...|||| . |. .... .. |.. |.||.. .|      ....| |.  ||||.||| |||...|. |.. . .||. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHSSPVGCHGRLKSTNCLIDARWMVRLSSFGL-----RELRGEET----------WQQ-EDDVQEGKDQLWTSPELLRWSTGLSQCG-----VLLVQKSD
||.||...||.|||.||..|.||.| .. |||     .... ...          ||. .|.  . |..|||.||.||...  .|.|     ..  || |
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSLAIVLYELFGRLG-----PWGDE----PMEPREIVSLVKREALAGK-KPFRPDMAVLK-----ESPRIVQETVVAAWTEDPLNRPS-LHQIKRKLKP
|||..|..||...| |     |....     ..|.||.  ||.. . |  |||||..   .     | .  . . . . |.||| .||. ..||. .|| 
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-15.AA RGC 454-706 32 1.1e-109 370.75 In-house 1-300 (300) Show / Hide 
Range on Protein: 454-706
Range on HMM: 1-300/300
Sequence Identity: 32% (97 aa)

EGRTVALKRIYRS----DVEFTRSNRLEIAKLQESVNSNVIEFVGMVVQSP------DVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEY
||..|..|.. ..    ...|||| . |. .... .. |.. |.||.. .|      ....| |.  ||||.||| |||...|. |.. . .||. |..|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHSSPVGCHGRLKSTNCLIDARWMVRLSSFGL-----RELRGEET----------WQQ-EDDVQEGKDQLWTSPELLRWSTGLSQCG-----VLLVQKSD
||.||...||.|||.||..|.||.| .. |||     .... ...          ||. .|.  . |..|||.||.||...  .|.|     ..  || |
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSLAIVLYELFGRLG-----PWGDE----PMEPREIVSLVKREALAGK-KPFRPDMAVLK-----ESPRIVQETVVAAWTEDPLNRPS-LHQIKRKLKP
|||..|..||...| |     |....     ..|.||.  ||.. . |  |||||..   .     | .  . . . . |.||| .||. ..||. .|| 
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-15.AA TKL 451-704 18 1.1e-25 89.4 In-house 12-364 (364) Show / Hide 
Range on Protein: 451-704
Range on HMM: 12-364/364
Sequence Identity: 18% (68 aa)

GLYEG----------RTVALKRIYRSDVEF--------------------------TRSNRLEIAKLQESV-NSNVIEFVGMVVQSPD------------
| . |          ..|| |.. . .. .                           |  . | ...  .    |.. |.| . ..|.            
GKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWG

-VFVVYELAQRGS-LKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHS-------SPVGCHGRLKSTNCLIDARWM--------------VRLSSFGLREL
  . |.|....|| | ...           | .. .||  |..||||        |   |  ||| |.|.|  |               . .. |||   
QLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRF

RGEETWQQEDDVQ----------------EGKDQLWTSPELLRWSTGLSQC--------GVLLVQKSDVYSLAIVLYELFGRLGPWGDEPMEPREIV---
  ... ..                     ..    | .||.|| .. ....        |    .|.|||| .|||.|.. |  |. |.|..|...    
MSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPF

-SLVKREALAGKKPFRPDMAVL-------KESPRIVQETVVAAWTEDPLNRPSLHQIKRKL
    .  .. |..| .|.           .  |. . .     | .|| .|||  .|. .|
EEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase gcy-15.AA TKL-Unique 488-634 27 6.7e-17 56.28 In-house 57-222 (290) Show / Hide 
Range on Protein: 488-634
Range on HMM: 57-222/290
Sequence Identity: 27% (48 aa)

NVIEFVGMVV----QSPDVFVVYELAQRGSLKDILD---------NDDMPLDDVFRSQMTKDIIAGLEYLHSSP--VGCHGRLKSTNCLIDAR-----WM
|.  ..|  .    . |. . | |  ..||| | |.         |. ..|.   | .| .||  |..|||..   .  |. |||.| |.| .     | 
NIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPI-IHRDLKSSNFLVDNNSNIAEWN

VRLSSFGLRELRGEE---TWQQE----DDVQEGKDQLWTSPELLRWSTGLSQCGVLLVQKSDVYSLAIVLYELF
.... |||. ..  .   |        ... .|   .| .||.|| .        .  .|||||| .|||.|..
IKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGS-FRWMAPEVLRMNF------CQYSEKSDVYSFGIVLWEIA
Kinase gcy-15.AA TK 488-704 14 1.4e-15 47.99 In-house 104-486 (486) Show / Hide 
Range on Protein: 488-704
Range on HMM: 104-486/486
Sequence Identity: 14% (55 aa)

NVIEFVGMVVQS------------PDVFVVYELAQRGS----LKDILDNDDMP-----------------------------------------------
|.. ..| ..|.            . . .| |... |.    |.| | . . .                                               
NIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

----------------------------LDDVFRSQMTKDIIAGLEYLHSSPV-----GCHGRLKSTNCLIDARWM-----------VRLSSFGLR----
                            |.   .  |  .| .|.||||| ..       |. |   |||.. .             .... |||     
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS

--ELR----GEETWQQEDDVQEG------------------KDQL---WTSPELLRWSTGLSQC--GVLLVQKSDVYSLAIVLYELF--GRLGPWGDEPM
    |    ... . ...    .                  ...|   |..|| |. .   |..        ||||.|. ....|.|  |.  . |. . 
GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN-DRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSN

-------EPREIVSLVKRE--------------ALAGKKPFRPD------MAVLKESPRIVQETVVAAWTEDPLNRPSLHQIKRKL
       ...|.. ...|.                  . |  ||      .    . | ....     | .||  ||.  |....|
QDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase gcy-15.AA DRK 488-575 37 4.9e-14 43.96 In-house 58-146 (258) Show / Hide 
Range on Protein: 488-575
Range on HMM: 58-146/258
Sequence Identity: 37% (33 aa)

NVIEFVGMVVQSPDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHSS-PVGCHGRLKSTNCLIDARWMVRLSSFGL
|.. | |    .||. .. |   ||||  || .. . .|   . ||  |.  |. |||.. |.  |  ||| | |.|  | |  . |||
NICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL
S_TKc gcy-15.AA S_TKc 442-708 16 8.1e-13 11.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 442-708
Range on HMM: 1-231/231
Sequence Identity: 16% (49 aa)

WHQIPDFGVGLY----------EGRTVALKRIYRSDVEFTRSNRLEIAKLQESVNSNVIEFVGMVVQSPDVFVVYELAQR--GSLKDILDNDDMP-----
.. .   | | .           || ||.|.|        .. | ||. |..    |.. . .. .   ....| |..    |.|.|....   .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDDVFRSQMTKDIIAGLEYLHSSPVGCHGRLKSTNCLIDARWMVRLSSFGLRELRGEETWQQEDDVQEGKDQL----WTSPELLRWSTGLSQCGVLLVQK
..      ... |. .|||.||  . .|  ||  | |.|    . .. |||  .               . .     . .||.|               |
FPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL----------GYGKCK

SDVYSLAIVLYELFGRLGPWGDEPMEPREIVSLVKREALAGKKPFRPDMAVLKESPRIVQETVVAAWTEDPLNRPSLHQIKR-----KLKPLT
.|..|. ..|||.. .  |.     .. ..  ...                    .. . . .   .. || .||.  .. .     |. |  
CDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase gcy-15.AA Dicty4-Unclassified 598-704 32 3.1e-12 38.19 In-house 174-263 (263) Show / Hide 
Range on Protein: 598-704
Range on HMM: 174-263/263
Sequence Identity: 32% (35 aa)

WTSPELLRWSTGLSQCGVLLVQKSDVYSLAIVLYELFGRLGPWGDEPMEPREIVSLVKREALAGKKPFRPDMAVLKESPRIVQETVVAAWTEDPLNRPSL
|.||| |.        .    ||||||| |..||||       ||||    || | .    .   |  || .      .  ..  ..  | .||  ||..
WESPECLM--------HESYNQKSDVYSYAMMLYELAT-----GDEPY--QEIQSIMNAARSVCDKKLRPKIP--DNCDNFWKKLIKWCWHNDPNKRPTM

HQIKRKL
 ||  .|
NQIIQYL
Kinase gcy-15.AA TESK 488-562 30 6.4e-12 33.48 In-house 54-127 (292) Show / Hide 
Range on Protein: 488-562
Range on HMM: 54-127/292
Sequence Identity: 30% (23 aa)

NVIEFVGMVVQSPDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHSSPVGCHGRLKSTNCLI
|.. | |  |.   .  . |    |.| ..|......|    . ..  ||  |. ||||  | .|  | | |||.
NILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGV-FHRDLTSKNCLV
Kinase gcy-15.AA RAF 532-709 25 1.7e-10 29.93 In-house 107-282 (282) Show / Hide 
Range on Protein: 532-709
Range on HMM: 107-282/282
Sequence Identity: 25% (48 aa)

QMTKDIIAGLEYLHSSPVGCHGRLKSTNCLIDARWMVRLSSFGLRELRGEETWQQEDDVQEGKDQ-LWTSPELLR------WSTGLSQCGVLLVQKSDVY
.  . .  |..|||.  .  |  ||| | . .    |.   |||  ..  .. . .  ..      || .||  |          | |      ..||||
DISRQVCQGMDYLHAKNI-IHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVY

SLAIVLYELFGRLGPWGDEPMEPREIVSLVKREALAGKKPFRPDM-AVLKESPRIVQETVVAAWTEDPLNRPSLHQIKRKLKPLTI
|  ||.|||  |  | | .  .   |. ..      |..  |||. .|... |.  .. .   |  .. .||.  ||   || .|.
SFGIVMYELMTRHMPYGCHIWNRDQIIFMC------GRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQI---LKRITV
TyrKc gcy-15.AA TyrKc 448-704 22 3e-10 -57.06 SMART 12-280 (280) Show / Hide 
Range on Protein: 448-704
Range on HMM: 12-280/280
Sequence Identity: 22% (64 aa)

FGV---GLYEGRTVALKRIYRSDVEFTRSNRLEIAKLQES--VNSNVIEFVGMVVQS-------PDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTK
||.   | .  ..|| | .  .     .  . |.  . .    . |.. ..| ..|.       . ...| |..  |.||| | .    |      ..  
FGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCW

DIIAGLEYLHSSPVGCHGRLKSTNCLIDARWMVRLSSFGL-RELRGEETW---QQEDDVQE--GKDQL----WTSPELLRWSTGLSQCGVLLV--QKSDV
.| .| ||||| ..  |  |   |||....  |. | ||| |..  . ..   ..  ...|  |.. .    |..|| .             .   ||||
QIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----------NYGKFTTKSDV

YSLAIVLYELF--GRLGPWGDEP--MEPREIVSLVKREALAGKKPFRPDMAVLKE-----SPRIVQETVVAAWTEDPLNRPSLHQIKRKL
.|  ....|.|  |   ..|..   |...|.. .||    .|. . .|. .   .      |  . .     | ||| .||.  .|....
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK----QGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase gcy-15.AA Dicty4 488-575 29 3.7e-07 20.11 In-house 59-160 (277) Show / Hide 
Range on Protein: 488-575
Range on HMM: 59-160/277
Sequence Identity: 29% (30 aa)

NVIEFVGMVV----QSPDVFVVYELAQRGSLKDILDN------DDMPLD--DVFR-SQMTKDIIAGLEYLHS-SPVGCHGRLKSTNCLIDARWMVRLSSF
|.. | |       .....  | |.  .|.|  .| .      .  .||  .. |  .| .|.  |. .||.  ||  |  ||| | |.|. | |  . |
NICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDF

GL
||
GL
Kinase gcy-15.AA Dicty4 619-654 38 2.8e-05 13.73 In-house 196-231 (277) Show / Hide 
Range on Protein: 619-654
Range on HMM: 196-231/277
Sequence Identity: 38% (14 aa)

QKSDVYSLAIVLYELFGRLGPWGDEPMEPREIVSLV
.|.|||| .|||.|.. |  |   . |.. ..| .|
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAV
Kinase gcy-15.AA Pkinase 454-546 20 0.000313 16.04 Pfam 23-126 (293) Show / Hide 
Range on Protein: 454-546
Range on HMM: 23-126/293
Sequence Identity: 20% (21 aa)

EGRTVALKRIYRSDVEF--TRSNRL--EIAKLQESVNSNVIEFVGMVVQSPDVFVVYELAQRG----SLKDILD-NDDMPL--DDVFRSQMTKDIIAGLE
.|..||.|.| ... .    ...|.  ||. ...    |.... ...  .... .| |... |    .|.|..   .. ..  ..     . . |. |||
TGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLE

YLHS
|.||
YCHS
Kinase gcy-15.AA DRK 620-639 60 0.000696 9.08 In-house 182-201 (258) Show / Hide 
Range on Protein: 620-639
Range on HMM: 182-201/258
Sequence Identity: 60% (12 aa)

KSDVYSLAIVLYELFGRLGP
| |||| |||| |.  |. |
KADVYSFAIVLWECVTRQDP
Kinase gcy-15.AA TKL-Unique 687-704 44 0.000896 9.4 In-house 273-290 (290) Show / Hide 
Range on Protein: 687-704
Range on HMM: 273-290/290
Sequence Identity: 44% (8 aa)

WTEDPLNRPSLHQIKRKL
|. || .|||. .|  .|
WHHDPSQRPSFDEIIHRL
Kinase gcy-15.AA Pkinase_Tyr 488-546 29 0.001073 13.14 Pfam 65-129 (270) Show / Hide 
Range on Protein: 488-546
Range on HMM: 65-129/270
Sequence Identity: 29% (19 aa)

NVIEFVGMVV-QSPD--VFVVYELAQRGSLKDILDND---DMPLDDVFRSQMTKDIIAGLEYLHS
|.. ..| .. |.    ...| |... |.|.| | .    . ||.     ||  .| .|.|||.|
NIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase gcy-15.AA Pkinase 619-704 14 0.004704 11.88 Pfam 191-293 (293) Show / Hide 
Range on Protein: 619-704
Range on HMM: 191-293/293
Sequence Identity: 14% (15 aa)

QKSDVYSLAIVLYELFGRLGPWGDE----PMEPREIVSLVKREALAGKKPFRPDMA------------VLKESPRIVQETVVAAWTEDPLNRPSLHQIKR
.|.|..|. ..|||.. .  |. ..    ........ ....  |    |   ..             . .. ..  .. .   .. ||  ||. .||. 
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

K--L
   .
HPWF
Kinase gcy-15.AA DRK 687-706 40 0.009434 5.19 In-house 239-258 (258) Show / Hide 
Range on Protein: 687-706
Range on HMM: 239-258/258
Sequence Identity: 40% (8 aa)

WTEDPLNRPSLHQIKRKLKP
| |||  |||. ..   |  
WNEDPQHRPSMQECLERLEA
Kinase gcy-15.AA Pkinase_Tyr 687-704 38 0.042475 7.73 Pfam 253-270 (270) Show / Hide 
Range on Protein: 687-704
Range on HMM: 253-270/270
Sequence Identity: 38% (7 aa)

WTEDPLNRPSLHQIKRKL
| .|| .||.  .| ..|
WHYDPEDRPTFSEIHEQL
Kinase gcy-15.AA Dicty4-Unclassified 536-575 32 0.065724 2.28 In-house 117-155 (263) Show / Hide 
Range on Protein: 536-575
Range on HMM: 117-155/263
Sequence Identity: 32% (13 aa)

DIIAGLEYLHSSPVGCHGRLKSTNCLIDARWMVRLSSFGL
||  |. .||.  .  |  .|| | |.|    ..   ||.
DIAQGMQHLHTRNF-IHRDIKSSNILMDKHFNIKIADFGI
Kinase gcy-15.AA Dicty4 687-706 36 0.082298 2.02 In-house 256-277 (277) Show / Hide 
Range on Protein: 687-706
Range on HMM: 256-277/277
Sequence Identity: 36% (8 aa)

WTEDPLNRPSLHQIKRK--LKP
| .|| .|||  .|  .  |  
WDHDPQHRPSFEEIIQRRILEH
Kinase gcy-15.AA Pkinase_Tyr 620-634 46 0.384413 4.49 Pfam 194-208 (270) Show / Hide 
Range on Protein: 620-634
Range on HMM: 194-208/270
Sequence Identity: 46% (7 aa)

KSDVYSLAIVLYELF
||||.|  ....|.|
KSDVWSFGVLMWEIF
CYCc gcy-15.AA CYCc 743-948 37 4.3e-83 283.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 743-948
Range on HMM: 1-231/231
Sequence Identity: 37% (90 aa)

AEKAKSEALLKMMLPEVVADSLKLGS-NVSAESFENCTVFFSDCPGFVEMSATSKPIDIVQFLNDLYTVFDRIIDQFD-----VYKVETIADAYMVASGL
.|| | . || .|||. ||..|| |   | .......|. |.| .|| ...... |...| .|||.|| ||||||...     .|||||| |||||.||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PVPNG-------------------NHHAGEIASLGLALLKAVESFKIRHL----PNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGI
| .|.                     || .||. .|  ......|...|     |....|.|||...||.|.||||..|||||.||||||.||||||.| 
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

RKFFWVAEPVSSLRINCSGTAKEIL-------DQLGGYEIEE
             .|..| .....|          |..|.|.
PG-----------QIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-15.AA Guanylate_cyc 770-967 36 2.5e-77 268.01 Pfam 1-214 (214) Show / Hide 
Range on Protein: 770-967
Range on HMM: 1-214/214
Sequence Identity: 36% (81 aa)

VSAESFENCTVFFSDCPGFVEMSATSK----PIDIVQFLNDLYTVFDRIIDQF--DVYKVETIADAYMVASGLPVP-----NGNHHAGEIASLGLALLKA
| |......|..|.| .|| .... .     |. .|..|||.|| |||..||.  ..|||.|| |.||..||||.|     .. |||  .|  .|.....
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

VESFKIRHLPNEK-----VRLRIGMNSGPCVAGVVG--LKMPRYCLFGDTVNTASRMESNGIRKFFWVAEPVSSL--RINCSGTAKEILDQLGGYEIE--
.... . |.. |      ...|||...||.||||.|  ..|||||..|||||.||||||.|.            .  .|. | .....| .......|  
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGV-----------PGSCKIHVSEETYRCLKCHENFQFECH

--ERGIVEMKGKGKQ---MTYFVRG
  .||....|||||.    |||. |
LQHRGEIPVKGKGKMGEMETYFLHG
HNOBA gcy-15.AA HNOBA 738-764 48 0.000232 17.34 Pfam 208-234 (234) Show / Hide 
Range on Protein: 738-764
Range on HMM: 208-234/234
Sequence Identity: 48% (13 aa)

NEELEAEKAKSEALLKMMLPEVVADSL
..||| || |...||  |.|  ||. |
HRELEEEKKKTDDLLYSMFPKSVANRL