Gene gcy-14 (Nematode worm)

gcy-14

Species: Nematode worm
Alias: CE15213, aSWK275, gcy-14, ZC412.2
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 14870502-14865765, WormBase Genetic Map location: n/a,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
gcy-14.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 254 Kinase domain by global Sugen HMM Fasta, JSON
gcy-14.AA Protein Genbank 1170 None Fasta, JSON

Protein domain

Protein domains of gcy-14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor gcy-14.AA ANF_receptor 41-419 18 5.4e-54 190.49 Pfam 1-364 (364) Show / Hide 
Range on Protein: 41-419
Range on HMM: 1-364/364
Sequence Identity: 18% (75 aa)

TSAAAVLVARDRIRAEHLLDQYDFNFTVKFDEC----TEGLAGGKTVELINHDNVDVIIGPTCNRAGIAVASLAAYYNVPVFQWGLTTAADIGN--VSRY
  |.|.  | ..| |.. .   ........|.|    .   |.. ...... ..|..||||.|  . |.||..|...|.|...||  |.    .   .||
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCYCSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISWG-CTCPCLTDKAKNRY

PTTVTLSLDTHSM-ALGVREVLRR-FEWDEFVFIYSNDGDEEKCASM---KDDLEKMGIENSDVTLAY----MVQIQTVTLDALQKALTE-VSKRGRIII
|... .  .  .. .  . . ... | |.....||..|  . .. ..    .....   |. .  ..|    ||. ..    .. | . . .....|.|.
PYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYY-YWRGGCYFMEAFQDELREHGGNCVYYAYVSMVIPWDDDFMDYLKKIKDIIKMKARVIV

ACFANGRG--FKKAFVASTVLAGMSTDEYMYMFAEPQSRGFYVDEINGGEHYSWDDTDGNFVTGLTPEQIRDAYGKVLYICDNMGLPTTITPEFANFSSQ
 |.   ..  ......   . .|| ...| . .... . .....               .. . . ..  |.|.. || .     .. . .||| .| ..
MCCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-W-------------WYDDDMDNDKFREAMKGVLGF----TMH-P-SPEFQEFMQR

LISRMTEQPFNCVQDCSNSTYKVPATYAGQLFDAFYAYGVALNRSLTQDPTRANLK------NGSFVLSDI-G-MSFQGVGGGTVTLDDTGTRIVQVYMF
.                  |   . .||....||.|.|. ||.. |..|| . | .      .|. .|. .   ..|.||  |.|..||.| | .. .. 
WKK----------------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGV-TGDVQFDDNGGRRPDYMYW

ALNTS
..|. 
IMNWD
Kinase gcy-14.AA RGC 622-861 34 2.2e-129 436.16 In-house 1-300 (300) Show / Hide 
Range on Protein: 622-861
Range on HMM: 1-300/300
Sequence Identity: 34% (104 aa)

QQDILAAMKHDLILQFDAEQK--AEFRQ---MRNFDNDNLNKFIGLCLDGP------QLFSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLLF
..|  ...||  . .|..     ...|.   ||. ..||||||||.|.|.|      .....|..|||||| |........||..|..|.|||| .|. .
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

IHNSFLKCHGHLTSRCCLIDDRWQIKISGYGLK----------------------SVR-TFENPKKEDLLWTPPENLRNENEERLPE-----------GD
.|.|....||.|.|..|..|.||..||...||.                      ..|   |.|.....|||.|| ||.... .  .           ||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFGIICSEILTRSSAFDLE-----------NRKEKPDVIIYQVKKGGHNPMRPSLDTGET---VEINPALLHLIRDCWTERPSERPS-IEQVRGHLNG
.||||||..||.||....|||           ...|... ..|..||||..| |||....|.   .|.||.||||.||||.|.|.|||. ..|.| .|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-14.AA RGC 622-861 34 2.2e-129 436.16 In-house 1-300 (300) Show / Hide 
Range on Protein: 622-861
Range on HMM: 1-300/300
Sequence Identity: 34% (104 aa)

QQDILAAMKHDLILQFDAEQK--AEFRQ---MRNFDNDNLNKFIGLCLDGP------QLFSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLLF
..|  ...||  . .|..     ...|.   ||. ..||||||||.|.|.|      .....|..|||||| |........||..|..|.|||| .|. .
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

IHNSFLKCHGHLTSRCCLIDDRWQIKISGYGLK----------------------SVR-TFENPKKEDLLWTPPENLRNENEERLPE-----------GD
.|.|....||.|.|..|..|.||..||...||.                      ..|   |.|.....|||.|| ||.... .  .           ||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

IYSFGIICSEILTRSSAFDLE-----------NRKEKPDVIIYQVKKGGHNPMRPSLDTGET---VEINPALLHLIRDCWTERPSERPS-IEQVRGHLNG
.||||||..||.||....|||           ...|... ..|..||||..| |||....|.   .|.||.||||.||||.|.|.|||. ..|.| .|..
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase gcy-14.AA TKL 636-859 18 3.8e-26 91.13 In-house 67-364 (364) Show / Hide 
Range on Protein: 636-859
Range on HMM: 67-364/364
Sequence Identity: 18% (57 aa)

QFDAEQKAEFRQMRNFDNDNLNKFIGLCLDGPQ-------------LFSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLLFIHNSFL------
.|  . . | ..|.... .|. .|.| |...|.             |.    .|..||| ...           ......||. |. . |..        
WFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKP

-KCHGHLTSRCCLIDDRWQ--------------IKISGYGLKSVRT-----------------------FENPKKEDLLWTPPENLRNE-----------
   |  |.|. .|.|. |.              .||. .||  . .                         ...   . | .|| ||..           
PIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE

---NEERLPEGDIYSFGIICSEILTRSSAFD-LENRKEKPD----VIIYQVKKGGHNPMRP-----SLDTGETVEINPA---LLHLIRDCWTERPSERPS
   ..|  .  |.|||||.  |||||   .. . .. ...      ....| . |. | .|      .     .  ...   .  |. ||| . |..|||
FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPS

IEQVRGHL
 ...  .|
FQEILKRL
Kinase gcy-14.AA TKL-Unique 648-790 23 4.3e-18 60.53 In-house 49-224 (290) Show / Hide 
Range on Protein: 648-790
Range on HMM: 49-224/290
Sequence Identity: 23% (42 aa)

MRNFD-NDNLNKFIGLCL----DGPQLFSLWRFCSRGSLSDVIS---------KSSMQMDSFFMFSLIRDISNGLLFIHNSFL-KCHGHLTSRCCLIDDR
| ...  .|. ...| |     . |...    .|..||| ||..         .... ..   . ....||. |. ..|..     |. |.|.  |.| .
MKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNN

-----WQIKISGYGLKSVRT--FENPKKED-----------LLWTPPENLRNENEERLPEGDIYSFGIICSEILTR
     |.|||.. ||  ...   .....|            ..| .|| ||.... .    |.|||||.  ||.||
SNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase gcy-14.AA TK 636-859 11 4.6e-13 39.36 In-house 71-486 (486) Show / Hide 
Range on Protein: 636-859
Range on HMM: 71-486/486
Sequence Identity: 11% (50 aa)

QFDAEQK---------AEFRQMRNFD-----NDNLNKFIGLCLDG------------PQLFSLWRFCSRGS----LSDVISKSSM---------------
.||.| .         .| . |  ..      .|. ...| |..|            . .  .  ... |.    | |   |..                
FFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNK

------------------------------------------------------------QMDSFFMFSLIRDISNGLLFIHNSFLK-----CHGHLTSR
                                                            |..   .    ..|..|. ..|    .      |. |  |
YPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAAR

CCLIDDRWQ-----------IKISGYGLK------SVRTFEN--------------------------------PKKEDLLWTPPENLRNENEERL----
 ||.... .           .||. .||         |  ..                                  |  . |..|| |.   . .     
NCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYG

---PEGDIYSFGIICSEILT---RSSAFDLENRKEKP----DVIIYQVKK------------GGHNPMRPSLDTGE-------TVEINPALLHL-IRDCW
   .. |..|||. . ||.|      . .. |..       . .. ....            |. ..| .  .  .       . . .|..... ...||
KFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCW

TERPSERPSIEQVRGHL
 . |..||. .|..  |
HYDPEDRPTFSQLHEQL
Kinase gcy-14.AA RIPK 760-859 25 1.2e-12 39.42 In-house 190-290 (290) Show / Hide 
Range on Protein: 760-859
Range on HMM: 190-290/290
Sequence Identity: 25% (28 aa)

PPENLRNENEER----LPEGDIYSFGIICSEILTRSSAFDLENRKEKPDVIIYQVKKGGHNPMRPSLDTGETVEINPA------LLHLIRDCWTERPSER
|||..|. |  .     |. |.|||.|.  |.||.  ..  .   .   .|.. .|.|    .||.|.  .  |  |       .  |...||   | .|
PPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMM---MIMMCCKQG----HRPCLQ--PVPEYWPEPPHCEQMIELMQRCWQQDPNDR

PSIEQVRGHL
|.   ..   
PCFQECEEWT
Kinase gcy-14.AA Pkinase 760-859 17 4.2e-11 40.33 Pfam 179-293 (293) Show / Hide 
Range on Protein: 760-859
Range on HMM: 179-293/293
Sequence Identity: 17% (21 aa)

PPENLRNENEERLPEGDIYSFGIICSEILTRSSAFDLEN----RKEKPDVIIYQVKKGGHNPMRPSLDT-------------GETVEINPALLHLIRDCW
.|| .| ....  |. |..|.|.|. | |..   |. .     .   ....|......     .| ...                ..........|..|.
APEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCL

TERPSERPSIEQVRGH--L
.  |..||..||.  |  .
CKDPKKRPTAEQILQHPWF
TyrKc gcy-14.AA TyrKc 614-859 19 4.1e-10 -59.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 614-859
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

INFI--------------FYYYQQDILAAMKHDLILQFDAEQKAEFRQ----MRNF--DNDNLNKFIGLCLDG-------PQLFSLWRFCSRGSLSDVIS
| ..               ..    |  | |    |. ||  ...|..    |...  ...|. ...| |...       ..|. .  ... |.| | . 
ITLGKKLGEGAFGEVYKGTWK----IQVAVK---MLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KSSMQMDSFFMFSLIRDISNGLLFIHNSFLKCHGHLTSRCCLIDDRWQIKISGYGLKSVRTFEN----------PKKE--DLL------WTPPENLRNEN
|.  .     . |   .|..|  ..|   .  |  |  | ||.... ..|||  || |    .            |||  .        |..|| .    
KHRPKLCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGL-SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----

EERL---PEGDIYSFGIICSEILTRSSAFDLE---NRKEKPDVIIYQVKKGGHNPMRPS-----LDTGETVEINPALLHLIRDCWTERPSERPSIEQVRG
       .. |..|||. . ||.|.      .   . . ... .| .||.|.  |  |.           |.  ...  ....|| | |..||. .... 
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

HL
 .
CF
Kinase gcy-14.AA RAF 776-859 25 5.5e-09 26.91 In-house 199-275 (275) Show / Hide 
Range on Protein: 776-859
Range on HMM: 199-275/275
Sequence Identity: 25% (21 aa)

DIYSFGIICSEILTRSSAFDLENRKEKPDVIIYQVKKGGHNPMRPSLDTGETVEINPALLHLIRDCWTERPSERPSIEQVRGHL
| |.||..  |.....  .  .. .|.   ||..| .|   . |.       | .  ..  |. .||.  | ||||  |.   .
DVYAFGTVWYELMAGEWPYQHIQWHEQ---IIWMVCRGYLRMDRSKA----RVQCPKEMKELLMECWSYQPEERPSFQQIMKMI
Kinase gcy-14.AA MLK 776-859 22 6.2e-08 23.74 In-house 218-291 (291) Show / Hide 
Range on Protein: 776-859
Range on HMM: 218-291/291
Sequence Identity: 22% (19 aa)

DIYSFGIICSEILTRSSAFDLENRKEKPDVIIYQVKKGGHNPMRPSLDTGETVEINPALLHLIRDCWTERPSERPSIEQVRGHL
|..|.|..  |.|||   ..  .  .   .... . .| . |....        ... .  |. .|| . |..|||  |.  ||
DVWSWGVVLWEMLTREVPYK--QHYDPMAIAWWVAYNGLRPPIPST--------CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
S_TKc gcy-14.AA S_TKc 620-859 15 8e-08 -62.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 620-859
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

YYQQDILAA--------MKHDL--------ILQFDAEQKAEFRQMRNFDNDNLNKFIGLCLDGPQLFSLWRFCSR--GSLSDVISKSSMQ-----MDSFF
|   ...           .|          |.      . | . ... . .|. |... . |   |.    .|.   |.| |.| |   .     ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

MFSLIRDISNGLLFIHNSFLKCHGHLTSRCCLIDDRWQIKISGYGLKSVRTFENPKKEDLL----WTPPENLRNENEERLP-EGDIYSFGIICSEILTRS
  .... | ..| ..|.    .|  |     |.|.  .|||.  ||  .          .     . .|| |        . . |..|.|.|  | |.. 
ARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGY

SAFDLENRKEKPDVIIYQVKKGGHNPMRPSLDTGETVEINPALLHLIRDCWTERPSERPSIEQVRG-------H--L
  |.        .  .... .                   | ....|| |..  |..||.. ..         |  .
PPFP-------QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase gcy-14.AA TKL-Unique 829-859 32 5.2e-07 20.96 In-house 260-290 (290) Show / Hide 
Range on Protein: 829-859
Range on HMM: 260-290/290
Sequence Identity: 32% (10 aa)

EINPALLHLIRDCWTERPSERPSIEQVRGHL
.... . .||..||.  ||.||| ....  |
HCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase gcy-14.AA TK-Unique 658-789 15 6.2e-07 20.08 In-house 68-234 (294) Show / Hide 
Range on Protein: 658-789
Range on HMM: 68-234/294
Sequence Identity: 15% (26 aa)

KFIGLCLDGP-QLFSLWRFCSRGSLSDVISKSSMQ-------------------------MDSFFMFSLIRDISNGLLFIHNSFLK--CHGHLTSRCCLI
...| | .   . . .. .|..|.| . . .. ..                          ....... . .| .|. ...   .|   |..| .| .|.
QCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLAS-QRKKIVHRDLCARNVLL

DDRWQIKISGYGLKS-------VRTFENPKKEDLLWTPPENLRNENEERLP---EGDIYSFGIICSEILT
 .. ..||...|.         . . .  ..  . | .|| |.    ..     ..|..|||..  ||.|
TEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCY--HGMYHTTKSDVWSFGVLMWEIFT
Kinase gcy-14.AA TK-Unique 837-859 43 3e-06 17.6 In-house 272-294 (294) Show / Hide 
Range on Protein: 837-859
Range on HMM: 272-294/294
Sequence Identity: 43% (10 aa)

LIRDCWTERPSERPSIEQVRGHL
|.. ||.. |.||||..|..  |
LMKSCWQWEPEERPSFRQIKHRL
Kinase gcy-14.AA UTK 833-859 29 1e-05 15.55 In-house 270-296 (296) Show / Hide 
Range on Protein: 833-859
Range on HMM: 270-296/296
Sequence Identity: 29% (8 aa)

ALLHLIRDCWTERPSERPSIEQVRGHL
..  | ..||.  |.|||..|...  .
PVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase gcy-14.AA Pkinase_Tyr 836-859 29 0.000111 16.48 Pfam 247-270 (270) Show / Hide 
Range on Protein: 836-859
Range on HMM: 247-270/270
Sequence Identity: 29% (7 aa)

HLIRDCWTERPSERPSIEQVRGHL
.|...|| . |..||. .... .|
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase gcy-14.AA UTK 648-742 16 0.000596 9.41 In-house 63-174 (296) Show / Hide 
Range on Protein: 648-742
Range on HMM: 63-174/296
Sequence Identity: 16% (19 aa)

MRNFD-NDNLNKFIGLCLDGPQLFSLWRFCSRGSLSDVISKSSMQMD-SFFMFS------LIRDISNGLLFIHNSFLKCHGHLTSRCCLIDDR-------
| .|.   |. ...|.|... ..  .......|.|...  ... . .   ....        .||..|. ..|.  .  |. |  | ||...        
MKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGF-VHRDLAARNCLVHMHRMMWHCM

WQIKISGYG---L
...||...|   .
MVCKIADFGRGGM
Kinase gcy-14.AA MLK 644-713 20 0.017116 4.62 In-house 55-142 (291) Show / Hide 
Range on Protein: 644-713
Range on HMM: 55-142/291
Sequence Identity: 20% (18 aa)

EFRQMRNFDNDN----LNKFIGLCLDGPQ-LFSLWRFCSRGSLSDVI---SKSSM----------QMDSFFMFSLIRDISNGLLFIHN
|.|. | ..  |      .| | ||. |. .. .  .|. |||..|.   .. .|           .|  ....   ....|. . |.
ECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS
Kinase gcy-14.AA UTK 776-790 53 0.019267 4.17 In-house 222-236 (296) Show / Hide 
Range on Protein: 776-790
Range on HMM: 222-236/296
Sequence Identity: 53% (8 aa)

DIYSFGIICSEILTR
|..|||. | ||.|.
DVWSFGVVCWEIWTW
CYCc gcy-14.AA CYCc 898-1093 44 1.8e-96 327.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 898-1093
Range on HMM: 1-231/231
Sequence Identity: 44% (102 aa)

EEKKKSDVLLYRMLPKMVADKLKLGQ-TVEPETFEQVTIFFSDVVQFTTLAGKCTPLQVVTLLNDLYTIFDGIIEQND-----VYKVETIGDGYLCVSGL
.||.| | ||..|||..||. || |. .|.|.... ||| |.|.| ||.|. .|||.|||..|||.|| || ||....     .||||||||.| .|||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PHRNG-------------------NEHIRHIARMSLGFLSSLEFFRVQHL----PSERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGK
|.||.                    .|.. || ..|. ..... | |||     | . ...||||..|.||.||||..|||||.|||.||.||||||.|.
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PGKIHVTAEANQML------TQVVGGFRTES
||.|||. |. . |      ..  |.|..| 
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc gcy-14.AA Guanylate_cyc 925-1112 42 4.8e-88 303.62 Pfam 1-214 (214) Show / Hide 
Range on Protein: 925-1112
Range on HMM: 1-214/214
Sequence Identity: 42% (92 aa)

VEPETFEQVTIFFSDVVQFTTLAGKCT----PLQVVTLLNDLYTIFDGIIEQN--DVYKVETIGDGYLCVSGLPHR-----NGNEHIRHIARMSLGFLSS
|... ...|||.|.|.| || .. .|.    |.|.|..|||.|| || ...|.  ..|||.|||| |.|||||| .     ..  |.. .| |.|... .
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

LEFFRVQHLPSER-----INLRIGINCGSVVAGVVG--LTMPRYCLFGDAVNTASRMESNGKPG--KIHVTAEANQMLTQVVG-GFRT--ESRGEVIIKG
.. ..|.|.. |.     |..||||..|.|||||.|  . |||||..|| ||.||||||.|.||  ||||..|. . |..  .  |..  ..|||. .||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGV---METYWLLG
||    ||||.| |
KGKMGEMETYFLHG
HNOBA gcy-14.AA HNOBA 893-919 62 5.9e-08 30.33 Pfam 208-234 (234) Show / Hide 
Range on Protein: 893-919
Range on HMM: 208-234/234
Sequence Identity: 62% (17 aa)

TKELVEEKKKSDVLLYRMLPKMVADKL
..|| |||||.| ||| |.|| ||..|
HRELEEEKKKTDDLLYSMFPKSVANRL