Gene F59A3.8 (Nematode worm)

F59A3.8

Species: Nematode worm
Alias: CE30549, F59A3.8, aSWK349
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 5525276-5522438, WormBase Genetic Map location: I:0.12,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
F59A3.8.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
F59A3.8.AA Protein Genbank 585 None Fasta, JSON

Protein domain

Protein domains of F59A3.8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 F59A3.8.AA SH2 178-293 26 3.4e-20 74.34 SMART 1-87 (87) Show / Hide 
Range on Protein: 178-293
Range on HMM: 1-87/87
Sequence Identity: 26% (32 aa)

MPNFHGYICREDAAQILKHP----GDWLVRLSVPPSNDQDKKNKAQNLAKSVERTKGHKSTMQKVFVISVLCKGKALSPAKSNNRNLVIKTNN-GKFSID
.| .|| | ||.| |.||.|    || ||| | .                           . . .|.|| .|        . ... .|..|. ||..||
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---------------------------NPGDYVLSVRWK--------GKVKHYRIRRNDDGKYYID

S--VHWLVKLKDLFSHYQGTSAV
    ..   | .|  ||| .. .
ETWRRKFPSL-ELVNHYQHNPLG
Kinase F59A3.8.AA Fer 318-578 40 2.3e-136 459.34 In-house 1-283 (283) Show / Hide 
Range on Protein: 318-578
Range on HMM: 1-283/283
Sequence Identity: 40% (114 aa)

ELLAKKLGEGAFGEVRVG-RLTTKDPKKKLVEV---AVKMLKSSADSVTRDQVEELLHETRIMRK-LDHPNVLRSYGVAVLREPLYLMIELCSNGALREY
  | |||||||||||. | | |.|  |.| ..|   |||. |  ....|..| .|..||.||||. .||||| . |||.|...|.....|.|..|.|..|
VTLGKKLGEGAFGEVYKGRR-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

LKENHK-TITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKT---PKVSDFGLAEL----TDRYEMK-EHCKIPVRYLAPETLELFIFTPKT
||.|.. |.....||......|.| .||||. ..|||.| ||.|...||.   .|.||||..      . .|.|| ..||.|.|.|||||.. .|..|||
LKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKT

DVFSFGCVIWEIYENGQ-----QPHDG-KNAQT----IRAQVKKREFLKLSSSAPEALRRLVAEKVFVADPENRCSMTSIVQCVE
||.|||...|||..||.     ||| | |....    ... .||. .... ...|..............|||.|..|..|.|...
DVWSFGVMCWEIFTNGAEPYPGQPH-GMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase F59A3.8.AA TyrKc 318-577 33 1.7e-107 364.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 318-577
Range on HMM: 1-280/280
Sequence Identity: 33% (99 aa)

ELLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKL--DHPNVLRSYGVAVLR-------EPLYLMIELCSNGA
  | |||||||||||. |...        ..|||||||..|       .|....| |||.||  .|||..| |||..         |||..  |....|.
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LREYLKENHKTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLAELTDRY-------EMKE-----HCK--IPVRYLAPETL
|..||..........|...| .  |.| .||||... ||||| ||.|..|..| |.|||||.   . .       ...      ..|  .|.| .|||..
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

ELFIFTPKTDVFSFGCVIWEIYENGQQPHDG-----KNAQTIRAQVKKREFLKLSSS--------APEALRRLVAEKVFVADPENRCSMTSIVQCV
   .||.|.||.||| ..|||. .||||. |     ...| ....||... ..   .        .|... . . ..   .|||.|.... |..| 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase F59A3.8.AA TK 318-577 18 1.6e-82 276.33 In-house 1-486 (486) Show / Hide 
Range on Protein: 318-577
Range on HMM: 1-486/486
Sequence Identity: 18% (89 aa)

ELLAKKLGEGAFG---EVRVGRLTTKDP--------------------KKKLVEVAVKMLKSSADSVTRDQVE-------------ELLHETRIMR--KL
  | ||||||.||   ||. |.. ...|                    ... ..|||||||. ...  ... .             |...|  .|.  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNVLRSYG-------------VAVLREPLYLMIELCSNGA----LREYLKENHKT-------------------------------------------
.|||..| ||             | |..||.... |....|     ||.||......                                           
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------ITLADKINFVLGSARGVAYLHSQ------RILHRDLAVRNILLTEDKT-----------PKVSDFGLA
                                .|..... . .  |.| .||||.      .. ||||| ||.|..|...            |..||||.
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

-----------ELTDRYEMKE------------------------HCKIPVRYLAPETLELFI---------FTPKTDVFSFGCVIWEIYENG-QQPHDG
           .  | |  |.                         .|.|.|..|||.|.  .         ||.|.||.|||...|||. .| .... |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

KNA---------QTIRAQVKKR------------EFLKLS--SSAPE-------------ALRRLVAEKVFVADPENRCSMTSIVQCV
 .          | .  ....             . . .     .|.             ..  ..  . . .||| | ... .... 
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Pkinase_Tyr F59A3.8.AA Pkinase_Tyr 317-577 34 2.8e-81 275.92 Pfam 1-270 (270) Show / Hide 
Range on Protein: 317-577
Range on HMM: 1-270/270
Sequence Identity: 34% (94 aa)

TELLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQ--VEELLHETRIMRKL-DHPNVLRSYGVAV-LREP--LYLMIELCSNGALR
 ... |||||||||||. |...  ||... ..|||||||   .. . .|   |....| .||..| .|||..| ||| .  .||  .|.  |.. .| |.
ITFG-KKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLK---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

EYLKEN---HKTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLAELT---DRY-EMKEHCKIPVRYLAPETLELFIFTPKT
.||...    . .|. |.... .  |.| .||.|... ||||| ||.|.||... |..||||| .    | |  .....|.|.. .||| .   .|| |.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DVFSFGCVIWEIYENGQQP-HDGKNAQTIRAQV-KKREFLKLSSSAPEALRRLVAEKVFVADPENRCSMTSIVQCV
|| ||| ..|||.  |.||   |   . . ... .... ..    .|. . .|   .   .|||.| ... |... 
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase F59A3.8.AA UTK 317-577 30 2.1e-61 208.82 In-house 1-296 (296) Show / Hide 
Range on Protein: 317-577
Range on HMM: 1-296/296
Sequence Identity: 30% (92 aa)

TELLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVE---ELLHETR---IMRKLD-HPNVLRSYGVAVLREPLYLMIELCSNGAL
..|. ..||.||||||...|.|. ..  ... |||| ..  ........ |   ... |.|   .| ... |||||| .|| .  ||... .|...|| |
VQLG-RQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ--HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDL

REYLKENHKT-------ITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTED-------KTPKVSDFG---LAELTDR-----------YEMKEH
| ||  ...|        || ... ...  |||..||||... ||||| ||.|....        . |..|||   .. .  .           |.|. |
RSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH

-CKIPVRYLAPETLELF-IFTPKTDVFSFGCVIWEIYENGQQPHDGKNAQTIRAQVKKREFLKLSS--SAPEALRRLVAEKVFVADPENRCSMTSIVQCV
 ...|.|  ||| |     || |.||.||| | |||. .|..|  | ... . .|| ..  . . .  . |... ||.  .   .||..|...  .|| .
QDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLM-HRCWHYDPQERPDFEDLVQQM
Kinase F59A3.8.AA TK-Unique 319-577 29 1.7e-58 200.25 In-house 2-294 (294) Show / Hide 
Range on Protein: 319-577
Range on HMM: 2-294/294
Sequence Identity: 29% (88 aa)

LLAKKLGEGAFGEVRVGRLTTKD-PKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKLD-HPNVLRSYGVAVLR-EPLYLMIELCSNGALREYLKE
 . ...||||||.|  | ..... .  | . ||||||| .|. .   .. ..| | ..|..|. |||... .|. .   || ....| |..| |. ||..
EVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDT---DKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRT

NHKT-------------------------ITLADKINFVLGSARGVAYLHS--QRILHRDLAVRNILLTEDKTPKVSDFGLA-ELTD--RYEMK-EHCKI
. ..                         |.. | ..|  . |.| .||.|  ..| ||||. ||.||||||. |..|||.| .. .   |.|. .  .|
CRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRI

PVRYLAPETLE--LFIF-TPKTDVFSFGCVIWEIYENGQQPHDGKNAQTIRAQVKKREFLKLSSSA-PEALRRLVAEKVFVADPENRCSMTSIVQCV
|.|..||| |     .. |.|.|| |||...|||  .|..|  |  .  |. ....   ... ..  ..... |  . ..  .|| | | ..|..  
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKS-CWQWEPEERPSFRQIKHRL
Kinase F59A3.8.AA SFK-Src 319-525 38 6e-50 145.88 In-house 2-202 (259) Show / Hide 
Range on Protein: 319-525
Range on HMM: 2-202/259
Sequence Identity: 38% (81 aa)

LLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREPLYLMIELCSNGALREYLKE-NH
 | ||||.| ||.|  ||   .       ||||| ||. | |      || |.|  .|.|| |||  . | |    ||.|   ||. .| |  ||.| . 
RLEKKLGSGQFGDVWKGRWNNT------TEVAVKTLKPGAMS-----AEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHG

KTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLA---ELTDR-YEMKEHCKIPVRYLAPETLELFIFTPKTDVFSFGCVIW
.  ..   .      | | |||  |   ||||| ||.|  .  . || |||..   .  |  |. .|  | |..  |||      |  | || |||  . 
RSLRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMM

EIYENGQQPHDG
||   |  | .|
EIVTYGRIPYPG
Kinase F59A3.8.AA Src 320-537 36 8.5e-50 167.34 In-house 3-215 (255) Show / Hide 
Range on Protein: 320-537
Range on HMM: 3-215/255
Sequence Identity: 36% (82 aa)

LAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREPLYLMIELCSNGALREYLK--ENH
| .|||.| ||||  |        .. ..|||| ||.        ..| .| |  || ||.|..... | |    || |   |. |.| | .|||  .  
LCRKLGQGQFGEVWMGYW------NGNTKVAVKTLKPGT-----MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEG

KTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLAELTD----RYEMKEHCKIPVRYLAPETLELFIFTPKTDVFSFGCVIW
... | . | .    |.| ||| |... ||||| ||.|  |.   || ||||| |..     |....  |.|..  ||| .    || |.|| |||  ..
RHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EIYENGQQPHDGKNAQTIRAQVKK
||   |. |  | . .    ||..
EIVTYGRVPYPGMTNHEVLQQVER
Kinase F59A3.8.AA Ack 320-531 36 2.7e-47 157.57 In-house 3-220 (266) Show / Hide 
Range on Protein: 320-531
Range on HMM: 3-220/266
Sequence Identity: 36% (82 aa)

LAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRD-QVEELLHETRIMRKLDHPNVLRSYGVAVLREPL-YLMIELCSNGALREYLKENH
| .|||.| || |. |  |.  |  | ..|||| |.|    .. .   ...| |  || .||||...| ||| ||  |.  .  ||.  |.| . |..  
LCEKLGDGCFGVVWRGEWTN--PGGKHIQVAVKCLRSD--KMQQPNCMDDFLREVAIMHSLDHPHLVRLYGV-VLDQPMLMMVTELAPCGSLLDCLRKHC

K--TITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTED-KTPKVSDFGLA----ELTDRYEMKEHC--KIPVRYLAPETLELFIFTPKTDVFSF
.    ...   .| .  | | .||...|..||||| |||||  | .. |..||||     .  |.| |..|   |.|    ||| |    |. . || .|
RTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMF

GCVIWEIYENGQQPHDGKNAQTI
|  .||    |..|  | |.  |
GVTLWEMFSYGEEPWAGCNGYQI
Kinase F59A3.8.AA TKL 324-516 23 4.7e-47 162.63 In-house 1-283 (364) Show / Hide 
Range on Protein: 324-516
Range on HMM: 1-283/364
Sequence Identity: 23% (68 aa)

LGEGAFGEVRVGRLTTKDPKKK----LVEVAVKMLKSSADSVTRDQV-----------------------EELLHETRIMRKLDHPNVLRSYGVAVLREP
.|.|.||||  |..   .  |.      .||||..||  |. . ..                        ...  |...|..|.|||... .|..   ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------LYLMIELCSNGALREYLKENHKTITLADKINFVLGSARGVAYLHSQR--------ILHRDLAVRNILLTEDKT--------------
             |..  |.|..| |..||        .  .....|. |||..||||..        |.||||  .|||. |. |              
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PKVSDFGLAELTDRYE--------------------MKEHCKIPVRYLAPETLE----------------LFIFTPKTDVFSFGCVIWEIY
.|..||||.   .. .                    .. ..    |..||| |.                 | ...|.||.||| |.|||.
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL
Kinase F59A3.8.AA Frk 320-537 34 1.7e-43 148.5 In-house 3-217 (260) Show / Hide 
Range on Protein: 320-537
Range on HMM: 3-217/260
Sequence Identity: 34% (78 aa)

LAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREPLYLMIELCSNGALREYLK---EN
| ..|| | ||||  |.   . |      |||| ||. .        ...| | .||.|| || ... | |  . ||.|.. ||  .|.| |||.   ..
LIRRLGSGQFGEVWEGLWNNTTP------VAVKTLKPGT-----MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDK

HKTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLAE---LTDR--YEMKEHCKIPVRYLAPETLELFIFTPKTDVFSFGCV
 . . .   ..     | |.||| ||  .||||| ||.|. |..  |. |||||      .   || .   ..|... |||  .   || | ||.||| .
GRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGIL

IWEIYENGQQPHDGKNAQTIRAQVKK
. ||   |. |  |   . .  .|..
LTEIITYGRMPYPGMTNAEVLQMVDH
Kinase F59A3.8.AA Eph 319-522 37 5.4e-42 138.78 In-house 2-210 (264) Show / Hide 
Range on Protein: 319-522
Range on HMM: 2-210/264
Sequence Identity: 37% (79 aa)

LLAKKLGEGAFGEVRVGRLTTKDPKKKL-VE-VAVKMLKSSADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREPLYLMIELCSNGALREYLKEN
 . | .|.| ||||. ||| ....|... |. ||.|.||   .. |  |  . | |  ||   ||||..|  ||   ..|.   .|   ||.| ..|...
KIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLK---AGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQH

HKTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLAE-LTDR------YEMKEHCKIPVRYLAPETLELFIFTPKTDVFSFG
   .| .  .    | | |  || .    ||||| ||||. ..   |||||||   | |.      |. .   |||.|  |||..   .||.  || |.|
DGQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYG

CVIWEIYENGQQP
 |.||.   |  |
IVMWEVMSYGERP
Kinase F59A3.8.AA S_TKc 318-577 24 2.8e-40 141.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 318-577
Range on HMM: 1-231/231
Sequence Identity: 24% (68 aa)

ELLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREPLYLMIELCSN--GALREYLKE
  . .|.|.||||.|. .| .         .||.|..|           | .. | .|..| .|||. . |.| .  . ||.  |.|..  | |..|.|.
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

NHK-----TITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDFGLAELTDRYEMKEHCKIPVRYLAPETLELFIFTP-KTDVFSFG
. .      ..  .   ..   .....|.||..|.||||   ||||.|  . |..||||| .        ..     |.||| |    ... | |. |.|
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

CVIWEIYENGQQPHDGKNAQTIRAQVKKREFLKLSSSAPEALRRLVAEKVFVADPENRCSMTSIVQ---------CV
|...| .  |. | .  . |..  ...           .. ..    .| .. |||.| .   . |          .
CILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F59A3.8.AA Pkinase 318-577 23 7.7e-36 127.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 318-577
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

ELLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREPLYLMIELCSNG----ALREYL
  . .|.|.|.||.|. ..           .|||| .| . ..   ||   .| | .||..|.|||..| |..   .  .|.  |.| .|     | .|.
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

K-ENHKTI--TLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTP----KVSDFGLAEL--TDRYEMKEHCKIPVRYLAPETLE-LFIFTPKT
. ..|...  .  . .....  .||..|.||..|.||||   |||. .. ..    |..|||||..  . ...   .     .|.||| .      .|| 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVFSFGCVIWEIYENGQQPHDGK-----------NAQTIRAQVKKREFLKLSSS---------------APEALRRLVAEKVFVADPENRCSMTSIVQC-
|..|.||...| .  |. | .|.            ... .....  .. . | |               ..|... .. .. .  ||. |.. . |.|  
DMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI-KWCLCKDPKKRPTAEQILQHP

-V
 .
WF