Gene F39F10.3 (Nematode worm)
F39F10.3
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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F39F10.3.AA | Protein | Genbank | 298 | None | Fasta, JSON |
F39F10.3.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 261 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of F39F10.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | F39F10.3.AA | Worm8 | 10-270 | 73 | 3.6e-263 | 770.46 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 10-270 Range on HMM: 1-261/261 Sequence Identity: 73% (193 aa) YTLEKLLGKGMYGEVHLCKDDRNNEARVAKLILKEHNGIRDKSWAHETLALNAVAGVNGVPRMFATGSTDYHNWIVMDLLSDDLEVIICRNENKKFAKAT |||||.||.||||.||||.||||||.||.|||.|||||.||..|.|||.||.|.|.||||||||..|||||||||||..|||||..||||||||.|.|.| YTLEKVLGRGMYGDVHLCQDDRNNEWRVMKLIHKEHNGHRDETWRHETFALTALADVNGVPRMFDYGSTDYHNWIVMEQLSDDLINIICRNENKMFSKPT GYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMFQLVLVDFGCARRFKDVNGNRTPPAPYPSNCIKGLHIPPHSALGMPHMEAEDIMQVAYLSCL ||||.||.||||.||||.||||||||..|||||||..||.||||||||...|||.|||||||||.||||....|.|.|.|.|.|||||||.||||||||. GYQIMWQLVKILQDIHSFGIVHGDIKADNLMVSHSNRMFMLVLVDFGCSCWFKDHNGNRTPPAPFPSNCMHLIHTPAHTANGHPHMEAEDLMQVAYLSCI LRQYAPWKDDDEFKMTRKKMSLALNPEKFLEEHQDLLPVIKLLAAQKHYAEPDYIAILDLL .|||.||||.||.|||..||..|.||.|||.|||||.|.||.||.||||.||||..|.||| CRQYMPWKDIDEHKMTKMKMKFAKNPKKFLGEHQDLKPIIKMLAKQKHYKEPDYKEIMDLL |
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Kinase | F39F10.3.AA | CK1 | 10-266 | 17 | 8.4e-56 | 191.71 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 10-266 Range on HMM: 1-339/339 Sequence Identity: 17% (61 aa) YTLEKLLGKGMYG-EVHLC-----KDDRNN-----EARVAKLILKE-----HNGIRDKSWAHETLALN---------------AVAGVNGVPRMFATGST ....|..|.| .| ..... || || | . |. |. . ... . .. ... . . ......... WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED DYHNWIVMDLLSDDLEVIIC--RNENKKFAKATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSH-------------SSNMFQLVLVDFGCAR-RFK ||.|..||.|| .|| . . |. |.|| . |...| .| .. |...|..|..| |||| |.... .... |....||| || ... DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR DVNGNR---------TPPAPYPS--------NCIKGLHIPPHSALGMPHMEAEDIMQVAYLSCLLRQYA---PWKDDDEFKM-------TRKKMSLALNP | .|.. . |... | . .... ||.... |. ..|. . . ||..... .. |. . . .. DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGC-TARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK EKFLEE----------HQDLLPVIKLLAAQKHYAEPDYIAI ... . .|.. ...| . ..|.| .||| .| MSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | F39F10.3.AA | TTBKL | 10-170 | 24 | 3.4e-22 | 71.78 | In-house | 1-180 (288) | Show / Hide |
Range on Protein: 10-170 Range on HMM: 1-180/288 Sequence Identity: 24% (44 aa) YTLEKLLGKGMYGEVHLCKDDRNNEARVAKLILKEHNGIRDKSWAHETLALNAVA--GVNGVPRMFATGSTDYHNWIVMDLLSDDLEVIICRNENKK-FA .. .|..|.| .|.| . .| . . . |. . | .. |. | |.. . | .|.. . | .. |..|| |....| .. .. ||| | WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS KATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSN----MFQLVLVDFGCARRFKDVNGN------------RTP . | . | |... ||..|..|..| |.|| | .. ... . |.||| ||.... .|. |.| DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRP |
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Kinase | F39F10.3.AA | Worm7 | 10-170 | 34 | 1.3e-18 | 58.97 | In-house | 1-164 (263) | Show / Hide |
Range on Protein: 10-170 Range on HMM: 1-164/263 Sequence Identity: 34% (56 aa) YTLEKLLGKGMYGEVHLCKDDRN-NEARVAKLILKEHN--GIRDKSWAHETLALNAVAGVNGVPRMFATGSTDYHNWIVMDLLSDDLEVIICRNENKKFA |.| . | | .||| | . | ....| | | | . || |. | | ..|..| . | ||| . | .. || || | YKLIHKIGNGQFGEVWQVIDKQDGNVPMIVKIINKYKNGSMKRDISYDREIEFFKYCHHVPNIPKLFHHFTHVGWNCIVMSEEGQNLRDVVKRNNNKPFS KATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMFQLVLVDFGCARRFKDVNGNRTP | ||. | || |. .| |.. | .|. . ..||.||| | |||||||| | TNNVIRIAWQIGSTLCFIHNKSFIHRDVHSQNVLVTLKNKVCKMVLIDFGNAVRFKDVNGNELP |
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Kinase | F39F10.3.AA | VRK | 68-163 | 28 | 1.3e-15 | 46.91 | In-house | 86-185 (284) | Show / Hide |
Range on Protein: 68-163 Range on HMM: 86-185/284 Sequence Identity: 28% (29 aa) GVPRMFATGSTDYH----NWIVMDLLSDDLEVIICRNENKKFAKATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMFQLVLVDFGCARRFKD |.| .. |..|. .||. . ||. |. . ...|.. | .| . .| .|... |||||| |...... | | .|||.| | |... GIPYCWGFGYHDFNGEKYRFMVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCP |
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Kinase | F39F10.3.AA | CK1-A | 10-163 | 28 | 4.4e-15 | 49.58 | In-house | 1-150 (261) | Show / Hide |
Range on Protein: 10-163 Range on HMM: 1-150/261 Sequence Identity: 28% (44 aa) YTLEKLLGKGMYGEVHLCKDDRNNEARVAKLILKEHNGIRDKSWAHETLALNAVAGVNGVPRMFATGSTDYHNWIVMDLLSDDLEVIICRNENKKFAKAT | | . .| | .|.. | .| | |. | | | |. . ..| |.|.| |. .| .||||| || . . ..|. | YRLVRKIGSGSFGDIYLGINITNGEEVAIKM---ESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCK-RRFTMKT GYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMFQLVLVDFGCARRFKD . |.. . .| |. .| |||| | .. .| |.||| |....| VLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRD |
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Kinase | F39F10.3.AA | CAMK | 15-168 | 15 | 6.7e-15 | 43.75 | In-house | 1-253 (425) | Show / Hide |
Range on Protein: 15-168 Range on HMM: 1-253/425 Sequence Identity: 15% (39 aa) LLGKGMYGEVHLCKDDRNN------------EARVAKLILKE------------------------HNGIRDKSWA---HETLALNAVAG------VNGV ||.| .|.|.||.. ... . .| | |. .. .|.|. . .| .. . | . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI PRMFA---------------TGST-----DYHNWIVM---DLLSDD------LEVIICRNEN------------KKFAKATGYQILWQVVKILKDIHSKG ... | |. | | ..|| .. | .. |. . . ..| . .. .|.. .. .||.. IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IVHGDIKPNNLMVSHSS--NM------------FQLVLVDFGCARRFKDVNGNR ||| |.|| |....... . ... ..||| |..|.. ..|. IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNF |
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Kinase | F39F10.3.AA | S_TKc | 10-286 | 14 | 1.2e-13 | 23.02 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 10-286 Range on HMM: 1-231/231 Sequence Identity: 14% (46 aa) YTLEKLLGKGMYGEVHLCKDDRNNEARVAKLILKEHNGIRDKSWAHETLALNAVAGVNGVPRMFATGSTDYHNWIVMDLLSD---DLEVIICRNENKK-- |.. ...||| .|.|..|.. . .. | | .. | | . . ... . . | ..||.... || .|... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --FAKATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMFQLVLVDFGCARRFKDVNGNRTPPAPYPSNCIKGLHIPPHSALGMPHMEAEDIMQ | . ...|... |. .||.||.| |.|| |..... .. . ||| ||.. .. | |. | .. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------------------TTFCGTPWYMAPEVL- VAYLS-------------CLLRQYAPWKDDDEFKMTRKKMSLALNPEKFLEEHQDLLPVIKLLAAQKHYAEPDYIAILDLLQQMLH-------SSGGGLA | .| | |. ....| .| . .|.....|. . |. -GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ -------NGSL . DEWDIKCHPWF |
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Kinase | F39F10.3.AA | Ciliate-E2 | 112-169 | 28 | 1.6e-12 | 39.29 | In-house | 149-214 (365) | Show / Hide |
Range on Protein: 112-169 Range on HMM: 149-214/365 Sequence Identity: 28% (21 aa) QILWQVVK---------------ILKDIHSKG-IVHGDIKPNNLMVSHSSNMFQLVLVDFGCARRFKDVNGNRT .| .|... |. .|||. |.| ||||.|... . ..||| .....| | ||| YIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFGLSKKYDDDNQNRT |
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Kinase | F39F10.3.AA | Ciliate-E2a | 112-163 | 28 | 6.9e-12 | 31.3 | In-house | 105-161 (275) | Show / Hide |
Range on Protein: 112-163 Range on HMM: 105-161/275 Sequence Identity: 28% (16 aa) QILWQVV-KILKDIHSKGIVHGDIKPNNLMVS-HSSNM---FQLVLVDFGCARRFKD .|..| . | .|...|.| |.|| |.. |.| ......||| |..... DIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDK |
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Kinase | F39F10.3.AA | Worm6 | 60-170 | 26 | 1.8e-10 | 34.07 | In-house | 52-174 (279) | Show / Hide |
Range on Protein: 60-170 Range on HMM: 52-174/279 Sequence Identity: 26% (32 aa) LNAVAGVN--GVPRMFATGSTDY--HNWIVMDLLSDDLEVIICRNENKKFAKATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSH-----SSNMFQL |.||. . ...... | .| |.||| |. .|. ... ...|| .||..| | . . | |. | .| |.|| | . . .. .. LKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTI VLVDFGCAR--RFKDVNG-NRTP ..||| .| .... .. ||| YMLDFGMCRRKKYCNKGNELRTP |
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Kinase | F39F10.3.AA | Pkinase | 71-169 | 23 | 1e-06 | 24.87 | Pfam | 67-169 (293) | Show / Hide |
Range on Protein: 71-169 Range on HMM: 67-169/293 Sequence Identity: 23% (26 aa) RMFATGSTDYHNWIVMDLLSD-----DLEVIICRNENKKF--AKATGYQILWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMF--QLVLVDFGCARRF ..| . . | ..||... || .| . ....| . ...|... |. .||.||.| |.|| |.... . . . . |||.|. | DWFED---KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQF -KDVNGNRT |. | DY-NNS-MT |
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Kinase | F39F10.3.AA | Ciliate-E2a | 10-46 | 27 | 4e-06 | 14.04 | In-house | 1-36 (275) | Show / Hide |
Range on Protein: 10-46 Range on HMM: 1-36/275 Sequence Identity: 27% (10 aa) YTLEKLLGKGMYGEVHLCKDDRNNEARVAKLILKEHN | ..|..||| .| | | . .... ...| . | .. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KM |
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Kinase | F39F10.3.AA | Ciliate-E2 | 10-34 | 32 | 5.1e-05 | 13.16 | In-house | 1-25 (365) | Show / Hide |
Range on Protein: 10-34 Range on HMM: 1-25/365 Sequence Identity: 32% (8 aa) YTLEKLLGKGMYGEVHLCKDDRNNE | . |..|.| .| | .||...... YKFIKKIGQGNFGSVYKCKVWKVQK |
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Kinase | F39F10.3.AA | Worm6 | 10-38 | 23 | 0.000113 | 13.08 | In-house | 1-30 (279) | Show / Hide |
Range on Protein: 10-38 Range on HMM: 1-30/279 Sequence Identity: 23% (7 aa) YTLEKLLGKGMYGEVHLCKDDRNNEA-RVA ....|..|.| .| | ...|. ... ..| WKVTKKIGEGGFGAVYKVEDKSDKKKKQFA |
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Kinase | F39F10.3.AA | Pkinase | 10-38 | 27 | 0.030491 | 9.01 | Pfam | 1-28 (293) | Show / Hide |
Range on Protein: 10-38 Range on HMM: 1-28/293 Sequence Identity: 27% (8 aa) YTLEKLLGKGMYGEVHLCKDDRNNEARVA |.... .|.| .|.| .|.. ... .|| YHIGRKIGSGSFGCVYKCHHKGTGK-IVA |
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Kinase | F39F10.3.AA | TTBKL | 215-270 | 17 | 0.043225 | 2.94 | In-house | 227-288 (288) | Show / Hide |
Range on Protein: 215-270 Range on HMM: 227-288/288 Sequence Identity: 17% (11 aa) PWKDDD-EFKMTRKKMSLALNPEKFLEEH-------QDLLPVIKLLAAQKHYAEPDYIAILDLL ||.. . . .. .|... . |.. .. . .... | | . . | .||| |. .. PWTNMEDKMEIEHMKKNMKD--EDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |