Gene F32B6.10 (Nematode worm)

F32B6.10

Species: Nematode worm
Alias: F32B6.4, CE20743, aSWK086, F32B6.10
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 9890037-9887168, WormBase Genetic Map location: IV:4.46,

Classification

Group: CK1
Family: TTBKL

Sequence

Name Sequence Type Origin Length Description Download
F32B6.10.AA Protein Genbank 540 None Fasta, JSON
F32B6.10.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 286 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of F32B6.10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F32B6.10.AA TTBKL 107-370 35 4.3e-115 388.67 In-house 1-288 (288) Show / Hide 
Range on Protein: 107-370
Range on HMM: 1-288/288
Sequence Identity: 35% (103 aa)

WMITHQIGEGTFAKIFVGRSLPF-DQYYAVKIEVRL-TSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKDLNFFVMTLLGENLRDLKLKCPDRR-FL
|||...|||| |.... ....   ....|.|.|..    .| . ..   .... .||  ||.|||..  |.|| ||.||||.|.||.||. . | .. | 
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

RGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADD-RKRSRIVHVIDFGLTRQWAWSKE--------KAFYARPLRT---KVQFRGSLNFTSSNA
.|||||.|||.|||||.||..||||||.|| |  .|. |. ..|.|.|..||||..||.||. .        .....|. |.   |..|||.....| |.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HLGYKLGRKDDLWSLLFTLVDLNDRLPWHGVKDHMILARQKMNMEDTPTSKY---------TFEEVELSEDDLEERFTGEWEEVTGEF
|... .||.|||||...... |...|||....|.|...  |.|| |.  .|.          |....     |. . .  .| .   |
HDRKEQGRHDDLWSWMYMIIELHCGLPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase F32B6.10.AA CK1 107-366 26 1.8e-85 290.29 In-house 1-339 (339) Show / Hide 
Range on Protein: 107-366
Range on HMM: 1-339/339
Sequence Identity: 26% (89 aa)

WMITHQIGEGTFA-KIFVG-----RSLPFD-----QYYAVKIEVR-LTSMDFIDHEVTVM-RLLSY-----------------PNELPHIPKCVFFSKQK
|.....|||| |   |. .     .... .     . ||.|.| .     ..  .|. .| ..| .                 ..  ||......  ...
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

DLN-FFVMTLLGENLRDLKL--KCPDRRFLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADD----------RKRSRIVHVIDFGLTR-QWA
| . . ||||||.|| ||.   ....|.|  .|| ...||.|.||. ||..|||||||||.|..||....          ....|.|..||||. | . .
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

WS---------KEKAFYARPLRT---KVQFRG-SLNFTSSNAHLGYKLGRKDDLWSLLFTLVDLNDR---LPWHGVKDHMI-----LARQKMNMEDTPTS
 .         ..| .  || |.   |..|||  . ..| |.|||  .||.|||||....|.....    |||...||.|        ..|... |..  
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

KY---------------TFEEVELSEDDLEERFTGEWEEV
..                | ..    . |.   . ..|..
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase F32B6.10.AA TTBK 107-324 35 2.7e-41 143.5 In-house 1-212 (257) Show / Hide 
Range on Protein: 107-324
Range on HMM: 1-212/257
Sequence Identity: 35% (77 aa)

WMITHQIGEGTFAKIFVGRSLPFD-QYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKDLNFFVMTLLGENLRDLKLKCPDRRFLRG
| ..  || | |  |. .  .  .    |.|.|   .       || |.. |      .|. . .      . |. ||.|.|.|| ||  | |.  |  .
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKL---QGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLS

TWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHLGYKLGRKDDLWS
|  |||.||| ...  |. || |||||| |  || .   .. |..  .|||| ||.  ..      || |    |||   . | |||.   .||.|||||
TTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRN--PSTCRKCYMLDFGLARQYTNACGE---VRPPREVAGFRGTVRYASINAHRNREMGRHDDLWS

LLFTLVD-LNDRLPWHGVKD
| . ||  ..  |||  .||
LFYMLVEFVQGQLPWRKIKD
Kinase F32B6.10.AA CK1 107-257 31 8.3e-33 110.35 In-house 1-155 (271) Show / Hide 
Range on Protein: 107-257
Range on HMM: 1-155/271
Sequence Identity: 31% (50 aa)

WMITHQIGEGTFAKIFVGRSLPFDQY---YAVKIEVRLTSMDFIDHEVTVMRLLSY---PNELPHIPKCVFFSKQ--KDLNFFVMTLLGENLRDLKLKCP
 ...  ||.| |  |. |  .  ..    .|.|.| . .    .. |. ... |      |. ..||..  . ..  .| |. ||.|||..| ||. .| 
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFC-

DRRFLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGL
.|.|   |   .. |..  .  .|.|.||||||||.| |||     |.. .|..|||||
NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR--YGKHCHQVYIIDFGL
Kinase F32B6.10.AA CK1-Unclassified 107-257 31 2.9e-32 92.52 In-house 1-154 (244) Show / Hide 
Range on Protein: 107-257
Range on HMM: 1-154/244
Sequence Identity: 31% (50 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELP-------HIPKCVFFSKQ--KDLNFFVMTLLGENLRDLKLKC
 ...  || | |  |. .  .  .. .|.|.| . .  . .. |. .|. |   .          .|||.  ....   | |. ||.|||..| ||. .|
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYL---QNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC

PDRRFLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGL
  |.|   |   .. |..  . ..|.|.||||||||.| |||     |.. .|. |||||
-NRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGK--LGKNHHQVYIIDFGL
Kinase F32B6.10.AA CK1-A 107-323 33 3.2e-31 107.51 In-house 1-209 (261) Show / Hide 
Range on Protein: 107-323
Range on HMM: 1-209/261
Sequence Identity: 33% (74 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKDLNFFVMTLLGENLRDLKLKCPDRRFLRGT
. . ..|| | |  |..| ..   .  |.|.| .      .  |  | |.|.     . ||.  .. ..|| | .|| |||  | ||   | .|||   |
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQ---GCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFC-KRRFTMKT

WSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHLGYKLGRKDDLWSL
   |  |..  .  .|||.||||||||.| |||   .|   .. ..|||||....  |. .     | |.  .  |   . | |||||    |.||. |.
VLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGI--GRHCNKL-FLIDFGLAKKYRDSRTRQHI--PYREDKNLTGTARYASINAHLGIEQSRRDDMESM

LFTLVDLN-DRLPWHGVK
 . ..  |  .||| |.|
GYVMMYFNRGKLPWQGMK
Kinase F32B6.10.AA CK1-D 107-323 32 5.2e-31 106.56 In-house 1-209 (261) Show / Hide 
Range on Protein: 107-323
Range on HMM: 1-209/261
Sequence Identity: 32% (71 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKDLNFFVMTLLGENLRDLKLKCPDRRFLRGT
. |  .|| | |  |. |  .  .   |.|.|   |    .. |  . ....    .|.|    .. .. | |  || |||  | ||   | .|.|   |
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEI---RWCGQEGDYNVMVMDLLGPSLEDLFNYC-HRKFSLKT

WSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHLGYKLGRKDDLWSL
   |. |..  .. .| . ||||||||.| |||     ||  .|..|||||....  .. .     | | . .  |   . | | |.|    |.||| ||
VLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLG---KRGNMVYIIDFGLAKRYRDARTHQHI--PYRENKNLTGTARYASINTHQGIEQSRRDDLESL

LFTLVDLND-RLPWHGVK
 . |.  |   ||| |.|
GYVLMYFNRGSLPWQGLK
Kinase F32B6.10.AA Worm6 107-325 30 1.1e-28 100.18 In-house 1-227 (279) Show / Hide 
Range on Protein: 107-325
Range on HMM: 1-227/279
Sequence Identity: 30% (71 aa)

WMITHQIGEGTFAKIFVGRSLPFDQ--YYAVKIEV--RLTSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKD--LNFFVMTLLGENLRDLKLKCPDR
| .|  ||||.|  ...           .|.| |   .  ..   ..|. |. ..   .  .| .| .   | .    |. ||||.|.||.||.  .|||
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHK-CRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDR

RFLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAA--DDRKRSRIVHVIDFGLTRQWAWSKEKAFY-----ARPLR-TKVQFRGSLNFTSSNAH
.|  ||  ...|| | |.  .|  ||||||.|| |   |    .... ....  .|||..|      .|..       |. | |...||| . . . ..|
KFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCR------RKKYCNKGNELRTPRWTACGFRGTVRYAPLACH

LGYKLGRKDDLWSLLFTLVDL-NDRLPWHGVKDH
 |  ..||||. | .  .|..   .|||...|||
KGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDH
Kinase F32B6.10.AA CK1-G 107-306 30 3.6e-21 68.43 In-house 1-194 (266) Show / Hide 
Range on Protein: 107-306
Range on HMM: 1-194/266
Sequence Identity: 30% (61 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELP-HIPKCVFFSKQKDLNFFVMTLLGENLRDLKLKCPDRRFLRG
. .   ||.| |  .| |. .    . |.|.| . .       |    ..|   |  |  ||.  .|      |  || |||  | ||   | ||.|   
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKIL---NGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWC-DRKFSVK

TWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHLGYKLGRKDDLWS
|   . ||..  .. .|..  | ||.||.| | |     |. ...|.||||. .|.   . |     | | .    |   . | | |||    | ||. .
TVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGR-PSNKDQHVIHIIDFGMAKQYIDPETKQHI--PYREHKSLTGTARYMSINTHLGREQSRRDDMEA

L
|
L
Kinase F32B6.10.AA CK1-Unique 176-313 24 1.8e-18 60.71 In-house 82-223 (337) Show / Hide 
Range on Protein: 176-313
Range on HMM: 82-223/337
Sequence Identity: 24% (35 aa)

KDLNFFVMTLLGENLRDLKLKCPDRRFLRG------TWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAF
.|  . |||..| ..  .. .     |  .      .  ..| |.| ..  ||. ||.||..|| |   .|.   .  .   ..|.|  |  .   ..  
RDWWWIVMTMHGPSMEECCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQ-HCYYMLDYGICRR-VFFVSNNH

YARPLRTKVQFRGSLNFTSSNAHLGYKLGRKDDLWSLLFTLVDL
  |. | .. ||| . . .   |.   .||.||. |....|..|
QIRQPRPITPFRGCKDYCPCSCHQCREHGRRDDMESWFYMLYHL
Kinase F32B6.10.AA S_TKc 107-494 14 1.9e-15 49.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 107-494
Range on HMM: 1-231/231
Sequence Identity: 14% (58 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKDLNFFVMTLLGE---NLRDLKLKCPDRR--
. |  .||.|.|.| . .|    ....|.||       . |  |. ...        |.| |.  .    |  ..|| ...    .|.|.  |.. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHLGYKLGR
  |   .  ..  ||. ||. .|..|.||||.||||.|.           . ..|||| ||                   | |.... .       . |.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL----------------TTFCGTPWYMAPEVL---GYGK

-KDDLWSLLFTLVDLND-RLPWHGVKDHMILARQKMNMEDTPTSKYTFEEVELSEDDLEERFTGEWEEVTGEFFAIDEVKINNPEKCSKLASEWKNPDVD
 | | ||.  .|  .   . |..   ... . .. .                                                                
CKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------------------------------------------------------------

VFQSASKNQKGSKMMLSYEFRLTGKNEEQTGKNEEKMNEYAYRWEKARERYRQRMLRLKLNDRNKQQFEAKNYMEQQIENDRRDRLDDIENVA-------
                                                                    |||. ...  . | ..|.   |  .       
------------------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

LKYL
  ..
HPWF
Kinase F32B6.10.AA Pkinase 213-306 30 4.3e-10 36.78 Pfam 116-198 (293) Show / Hide 
Range on Protein: 213-306
Range on HMM: 116-198/293
Sequence Identity: 30% (29 aa)

QILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHL-GYKLGRKDDLWSL
||| .|. .|..|.||||.||||.|.   .. .   .|...|||| .|            . .    | |.... .   .. | . |.| | ||.
QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC
Kinase F32B6.10.AA TyrKc 107-326 14 0.000146 -148.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 107-326
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLL--SYPNELPHIPKCVFFSKQ--KDLNFFVMTLLGENLRDLK--LKCPDR
    ...||| | ... |.     .  |||     . .  . .|  .|. |  . || .  .  |.  . .   .   .. . . ..  |||  |. . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKHRP

RFLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWS-------KEKAF----YARP-----------LRTK-
..   .     .||       |.|..||||.   | | |.        .| . ||||.| .          . .       ..            .... 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

----------------------VQFRG------SLNFTSSNAHLGYKLGRKDD--------LWSLLFTLV------DLNDRLPWHGVKDHM
                          |      |      .   || . . ..          . ....       | .||     ... .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase F32B6.10.AA CK1-Unclassified 286-306 57 0.001771 6.15 In-house 182-202 (244) Show / Hide 
Range on Protein: 286-306
Range on HMM: 182-202/244
Sequence Identity: 57% (12 aa)

FTSSNAHLGYKLGRKDDLWSL
..| |||||.  .|.||| ||
YASINAHLGIEQSRRDDLESL
Kinase F32B6.10.AA CK1 286-306 47 0.057082 2.81 In-house 182-202 (271) Show / Hide 
Range on Protein: 286-306
Range on HMM: 182-202/271
Sequence Identity: 47% (10 aa)

FTSSNAHLGYKLGRKDDLWSL
..| |.|||.  .|.||. ||
YASINTHLGIEQSRRDDMESL
Kinase F32B6.10.AA Pkinase 107-158 22 0.058097 8.02 Pfam 1-58 (293) Show / Hide 
Range on Protein: 107-158
Range on HMM: 1-58/293
Sequence Identity: 22% (13 aa)

WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDH------EVTVMRLLS
. |  .||.|.|.. . ..     . .||||  . .  .  |       |. .|. |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN