Gene F23C8.7 (Nematode worm)

F23C8.7

Species: Nematode worm
Alias: F23C8.7=F23C8.e, F23C8.7, aSWK376, CE20716
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 2425074-2422406, WormBase Genetic Map location: I:-8.78,

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
F23C8.7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
F23C8.7.AA Protein Genbank 417 None Fasta, JSON

Protein domain

Protein domains of F23C8.7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 F23C8.7.AA SH2 9-97 31 2.1e-25 91.63 SMART 1-87 (87) Show / Hide 
Range on Protein: 9-97
Range on HMM: 1-87/87
Sequence Identity: 31% (30 aa)

EHWYHGLLPREDIKAMLRKN----GDFLVRSTEPKAGEPRQYVLSAMQSEELEDAGVKHYVMRLNSSNQIFLEA---KGFETIASLVNYYMSSKEP
..|||| ..||.  ..|...    ||||||  |.   .|..|||| .        .||||. | | ... ...    . |...  |||.|.  . .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWK-----GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 F23C8.7.AA SH2 11-91 27 4.7e-16 48.95 Pfam 1-81 (81) Show / Hide 
Range on Protein: 11-91
Range on HMM: 1-81/81
Sequence Identity: 27% (24 aa)

WYHGLLPREDIKAMLRK----NGDFLVRSTEPKAGEPRQYVLSAMQSEELEDAGVKHYVMRLNSSN-QIFLEAKGFETIASLVNYY
|||| ..|..   .|..    .|.||||  | . |.   |.|| .   .     ||||. . .        . . |.... ||..|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD---YTLSVRDDGP--GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase F23C8.7.AA Fer 120-375 48 5.69999999999e-149 501.21 In-house 1-283 (283) Show / Hide 
Range on Protein: 120-375
Range on HMM: 1-283/283
Sequence Identity: 48% (137 aa)

VELTKKLGEGAFGEVWKG--KLTLKN---GNVENCAIKTAKL--ESLNKEQIKEIMREARLMRN-LDHPNVVKFYGVGASQEPLYVIMELADCGALDSYL
|.|.|||||||||||.||  .|..|.    .|...|.|..|.  |...||||||.|.|||.||| .||||||||||| ....|....||....|.|||||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

QKNPN-LVPD-KKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQVK----IADFGLSRE----GISYVMD-LTKKVPIRWLAPETLKAGIYSPKTD
.||.| .|.| .|..|.||||||. |.|.|. .|||||||||||. ..||    |.|||.||.    | .| |.   .|||||||||||.. ||||||||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VFAFGIMAWEITENGKEPYPD----MRVADV----VGKVRNGYRMRFDPVFVDFRFGDYVTKHCWAENPADRVSMADVLRYLQ
|..||.|.||| .||.||||.    |... |    . .......| . |  .  ..  ...|.||...| || .|... . | 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase F23C8.7.AA TyrKc 120-374 36 5.6e-107 362.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-280/280
Sequence Identity: 36% (106 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNL--DHPNVVKFYGVGASQ-------EPLYVIMELADCGALDSY
..| |||||||||||.||...      ...|.|. | ..     ....|||||.|..|  .|||.|..|||  .|       |||...||... |.|..|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LQKNPN-LVPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQ-VKIADFGLSREGISY--------VMDL----TKK--VPIRWLAPETLKAGI
|.|. . | .... .. .|.||| .| |.|.. |||.||||||.| .. |||.||||||.. ..        . .      .|  .||||.|||... |.
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YSPKTDVFAFGIMAWEITENGKEPYPD-----MRVADVVGKVRNGYRMRFDPV--------FVDFRFGDYVTKHCWAENPADRVSMADVLRYL
...|.||..||.. |||  .|..|||.     |  ..|. .|..||||.  |           |  .   . | ||.|.|.|| ..... ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRPTFSEIHECF
Kinase F23C8.7.AA Pkinase_Tyr 120-337 38 3.6e-94 319.54 Pfam 1-235 (270) Show / Hide 
Range on Protein: 120-337
Range on HMM: 1-235/270
Sequence Identity: 38% (92 aa)

VELTKKLGEGAFGEVWKGKLT-LKNGNVENCAIKTAKLESLNKEQ--IKEIMREARLMRNL-DHPNVVKFYGVGA-SQEP--LYVIMELADCGALDSYLQ
... |||||||||||.||... .. ..   .|.|.   |.  .||  ... ||||..|..| .|||.|..|||    .||  .|..||.. .| |..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----NPNLVPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYG-GGQVKIADFGLSREGIS---Y-VMDLTKKVPIRWLAPETLKAGIYSPKTDVFA
|    ...| .  . .| .| |.| .| ..|.. |||.|||||| . ...|||.||||.|   .   | ..    |.||.|.||| .. |... |.|| .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGIMAWEITENGKEP-YPDMRVADVVGKV-RNGYRM
||.  |||   |..| ||.|  ..|. .. ..||||
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRM
Kinase F23C8.7.AA TK 120-374 20 1.1e-92 311.06 In-house 1-486 (486) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-486/486
Sequence Identity: 20% (102 aa)

VELTKKLGEGAFG---EVWKGKLTL----------------------KNGNVENCAIKTAKLE-SLNKEQIKE--------------IMREARLMRN--L
..| ||||||.||   ||.||..                        |.|... .|.|. |.. . ..|. ..               ..|. .|..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNVVKFYG-------------VGASQEPLYVIMELADCGA----LDSYLQKNPN--------------------------------------------
.|||.|..||             |   |||....||....|     |..||.|...                                            
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LVPDKKMEMIYQAACGISYMHEK------KLLHRDIAARNCLYGGGQ------------VKIADFGLS
                                | .  .. | .|.||| .|.|.|      .. |||.|||||| | .             .||||||||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

RE----------------------------------GISYVMDLTK-KVPIRWLAPETLKAGI---------YSPKTDVFAFGIMAWEITENGKEPYPD-
|.                                  . .|... .. |.||||.|||.|. ..         ...|.||..||.. |||  .|.|||.  
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

MRV---------ADVVGKVRNG----------------------------YRMRFDPVFVDFRFGDYVTKHCWAENPADRVSMADVLRYL
|           ..|. ..|.|                            ||| . |  ..  . . . . ||...|.|| ........|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase F23C8.7.AA UTK 120-338 32 1.7e-68 233.47 In-house 1-262 (296) Show / Hide 
Range on Protein: 120-338
Range on HMM: 1-262/296
Sequence Identity: 32% (86 aa)

VELTKKLGEGAFGEVWKGKLTLKN--GNVENCAIKTAKLESLNKEQIK---EIMREAR---LMRNLD-HPNVVKFYGVGASQEPLYVIMELADCGALDSY
|.| ..||.|||||| |...|  .  . .  .|.|... ..    .     ..|.|||   .| ... ||||....||  ..||.....|..  | |.||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LQKNPN--------LVPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGG--------QVKIADFG---LSREGIS-----------YVMDL-TKK
|....         |  .....| .. |.| .|.|.... |||.|||||| .          ..||||||   .||.  .           |.|    ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

VPIRWLAPETLKAG-IYSPKTDVFAFGIMAWEITENGKEPYPDMRVADVVGKVRNG--YRMR
.|||| ||| |  .  .. |.||..||.  |||  .|. |||.|  ..|.  |.||  |||.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMP
Kinase F23C8.7.AA TK-Unique 120-337 32 3.3e-66 226.29 In-house 1-258 (294) Show / Hide 
Range on Protein: 120-337
Range on HMM: 1-258/294
Sequence Identity: 32% (84 aa)

VELTKKLGEGAFGEVWKGKLTLKN-GNVEN-CAIKTAKLESLNKEQIKEIMREARLMRNLD-HPNVVKFYGVGASQ-EPLYVIMELADCGALDSYLQKNP
.|. ...||||||.||.|... .. .. .  |.. ..  ....... .. ..|...|..|. |||.|...|.  .  || . ||| . || |..||... 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

NL----------------VPDKKMEM----------IYQAACGISYMHE--KKLLHRDIAARNCL-YGGGQVKIADFGLSRE---GISYVMDLT-KKVPI
                  .|||...           ..| ||| .|...  ||  |||..|||.|  .....||.|||..|.   .  |.|  . ...||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWLAPETLK--AGIY-SPKTDVFAFGIMAWEITENGKEPYPDMRVADVVGKVRNGYRM
||.||| ||   |.| ..|.|| .||.  |||  .|. |||.|. .|.. ..|.||||
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRM
Kinase F23C8.7.AA Src 120-337 37 2.9e-55 186.19 In-house 1-219 (255) Show / Hide 
Range on Protein: 120-337
Range on HMM: 1-219/255
Sequence Identity: 37% (86 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCGALDSYLQ---KNPN
. | .|||.| |||||.|.    |||..  |.|| |  ..  |.     .|| .| .|.|...|. | |    || | . |.   | |  ||.   .  .
IKLCRKLGQGQFGEVWMGYW---NGNTK-VAVKTLKPGTMSPEAFL---QEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRH

LVPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQ-VKIADFGLSREGIS-----YVMDLTKKVPIRWLAPETLKAGIYSPKTDVFAFGIMAWE
|   .  .|  | | | .|. .... ||| |||| | | .  .|.||||| |  |      |..    |.||.| ||| .  | .. |.||  |||  .|
LHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE

ITENGKEPYPDMRVADVVGKVRNGYRM
|   |. ||| |. ..|. .| .||||
IVTYGRVPYPGMTNHEVLQQVERGYRM
Kinase F23C8.7.AA Abl 120-374 34 1.8e-53 176.5 In-house 1-252 (252) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-252/252
Sequence Identity: 34% (90 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCGALDSYLQKN--PNL
. . .||| | .|||..|     .  |   |.|| | ...   ...| ..|| .|... |||.|.  ||     | |.| |    | |  || ..   .|
IMMKHKLGGGQYGEVYEGVWKRHDCTV---AVKTLKEDTM---EVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREEL

VPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQ-VKIADFGLSR--EGISYVMDLTKKVPIRWLAPETLKAGIYSPKTDVFAFGIMAWEITEN
 .   . |  | | |.||. ... .|||.|||||| |  . ||.|||||.|  ..  |      | ||.| ||| |    .| | ||.|||.. |||   
PAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATY

GKEPYPDMRVADVVGKVRNGYRMRFDPVFVDFRFGDYVTKHCWAENPADRVSMADVLRYL
|  ||| . . .| .|. .||||   .   .  .   . ..||  ...|| | ... . .
GMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVY--ELMRQCWQWSHTDRPSFKEIHHAM
Kinase F23C8.7.AA SFK-Abl 120-337 39 8.3e-53 170.55 In-house 1-216 (251) Show / Hide 
Range on Protein: 120-337
Range on HMM: 1-216/251
Sequence Identity: 39% (89 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCGALDSYLQKNPNLVP
. |   |||| .|||.||       |    |||| | ||.     |. |.||  |. . ||| |.  ||     |.|.. |    | | .|||     . 
IILGHRLGEGQYGEVYKGIW-----NNHRVAIKTIKDESM---ETKDFMKEAHIMKRMQHPNLVRLIGVCTREGPMYIVQEFMNYGNLLDYLQSPQSRIQ

DKKMEMIY---QAACGISYMHEKKLLHRDIAARNCLYGGG-QVKIADFGLSREGIS---YVMDLTKKVPIRWLAPETLKAGIYSPKTDVFAFGIMAWEIT
     |..   | | | | . |.   ||| |||||| |   |.|.||||. |  ..   |      | ||.| ||| |   |.. | || .|||  ||| 
IDHVSMMHCAQQIADGMSFLEEQHFIHRDLAARNCLVGDNLQIKVADFGMARF-VDSDFYEARIGTKMPIKWTAPESLCYDIFTIKSDVWSFGITLWEIA

ENGKEPYPDMRVADVVGKVRNGYRM
  |  ||| .   ||. .   ||||
TYGDVPYPGIHHRDVINQLMMGYRM
Kinase F23C8.7.AA TKL 126-374 20 4.6e-51 175.97 In-house 1-364 (364) Show / Hide 
Range on Protein: 126-374
Range on HMM: 1-364/364
Sequence Identity: 20% (76 aa)

LGEGAFGEVWKGKLTLKNGNV------ENCAIKTAKLESLNKEQI-------------------------KEIMREARLMRNLDHPNVVKFYGVGASQEP
.|.|.||||.|||.   .| .      .  |.|. | .. ... .                         ... .|...|..|.|||.|.|.|.  . ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------LYVIMELADCGALDSYLQKNPNLVPDKKMEMIYQAACGISYMHE--------KKLLHRDIAARNCLYGG-GQ--------------V
             |. .||....| | .||.      ..... .....|.|..|.|         ....|||.  .|.|    ..              .
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIADFGLSREG-----ISYVM--------------DLTKKV-PIRWLAPETLK----------------AGIYSPKTDVFAFGIMAWEITENGKEPYPDM
||.||||||.       .  |               . ...  .||.||| |.                 . ||.|.||..|||. |||    . || |.
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDY

RVADVV---------GKVRNGYRMRFDP------------VFVDFRFGDYVTKHCWAENPADRVSMADVLRYL
   ...          .| .  .    |              .. .. .   ..||...| .| |. ..| .|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKK-LMQDCWDHDPEKRPSFQEILKRL
Kinase F23C8.7.AA Frk 120-378 34 5.2e-51 174.92 In-house 1-260 (260) Show / Hide 
Range on Protein: 120-378
Range on HMM: 1-260/260
Sequence Identity: 34% (92 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCGALDSYLQ----KNP
..| ..|| | ||||| |.      |    |.|| |  ...    .. .|||..|..| || ... | | . .||.|.| ||   |.|  |||    |  
IQLIRRLGSGQFGEVWEGLWN----NTTPVAVKTLKPGTMD---PNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGR

NLVPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQ-VKIADFGLSR----EGI-SYVMDLTKKVPIRWLAPETLKAGIYSPKTDVFAFGIMAW
..   . ..|  | | |. |. ..  .|||.|||| | | .. .||||||| |    . .  |      ..||.| |||  .   .. | ||..|||.  
QCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLT

EITENGKEPYPDMRVADVVGKVRNGYRMRFDPVFVDFRFGDYVTKHCWAENPADRVSMADVLRYLQTTF
||   |. ||| |  |.|.  | .||||   |   . .. . .  .|| ..|  |     .   |.  |
EIITYGRMPYPGMTNAEVLQMVDHGYRMP-QPPNCPQQLYE-IMLECWHSDPMKRPTFETLQWKLEDYF
Kinase F23C8.7.AA Src-Echino1 120-374 34 1.6e-48 166.34 In-house 1-252 (252) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-252/252
Sequence Identity: 34% (89 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCGALDSYLQKNP--NL
....||.|.| .||||||   . ||| .  |.|| | ... .    . . || .|. . | ..|..| | . .||.|.. ||   | | .||...   ..
LRMDKKIGKGHCGEVWKG---VWNGNTP-VAVKTLKEKTMSPA---DFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHV

VPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQV-KIADFGLSR--EGISYVMDLTKKVPIRWLAPETLKAGIYSPKTDVFAFGIMAWEITEN
   . ..|  . | |. |. .| ..|||.|||| | | | | ||||||| |  .   |.     |.||.| |||    | .  | ||..|||.  |.   
KMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTF

GKEPYPDMRVADVVGKVRNGYRMRFDPVFVDFRFGDYVTKHCWAENPADRVSMADVLRYL
|. |||.|.  .|. .| .||||       |  . . .   ||  .|  |  .  .  ..
GRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLY-MMCMMKCWHKDPQQRPTFEFLHDFF
Kinase F23C8.7.AA S_TKc 120-374 24 5.2e-46 160.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-231/231
Sequence Identity: 24% (68 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMREARLMRNLDHPNVVKFYGVGASQEPLYVIMELADC--GALDSYLQKNPN-
 |. .|.|.||||.|.|.. .      . .|||  |         . |.|| ..... .|||.||.|.|  . . ||..||..|   | | .|..|..  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LVPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYGGGQVKIADFGLSREGISYVMDLTKKVPIRWLAPETLKAGIYSP-KTDVFAFGIMAWE
     . .     ..|| .|.. |.|... .|||.   | |    ..||.||||.|.        |  .   ..||| |    |.. | |. ..|.. .|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

ITENGKEPYPDMRVADVVGKVRNGYRMRFDPVFVDFRFGDYVTKHCWAENPADRVSMADVLR---------YL
    |. |.|   .. .  |..            .  . |   ..|.  .|..| .  ..|.         ..
MLC-GYPPFP--QMQMMFKKIG------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F23C8.7.AA Pkinase 120-374 20 1.2e-40 144.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-293/293
Sequence Identity: 20% (61 aa)

VELTKKLGEGAFGEVWKGKLTLKNGNVENCAIKTAKLESLNKEQIKEIMR--EARLMRNLDHPNVVKFYGVGASQEPLYVIMELADCG----ALDSYLQ-
 .. .|.|.|.||.|.|..    .      |.|. |... .... ..  |  |...|..|.|||.|..|..  .   .|..||....|     | .|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-KNPNL--VPDKKMEMIYQAACGISYMHEKKLLHRDIAARNCLYG-GGQV----KIADFGLSRE--GISYVMDLTKKVPIRWLAPETLK-AGIYSPKTDV
 .. ..   ..    ..|| ..|. |.|... .|||.   |.|.   |..    ||.||||..     ...   |  . ....||| .. .  |.|| |.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FAFGIMAWEITENGKEPYPDM----RVADVVGKVRNGYRMRFDPVFVDF---------------------RFGDYVTKHCWAENPADRVSMADVLRY--L
...|.. .|    |. |.|.     . .|   ....  . ...  .                        . .  . | |.. .|..| . ...|    .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase F23C8.7.AA Pkinase_Tyr 354-374 33 0.001979 12.24 Pfam 250-270 (270) Show / Hide 
Range on Protein: 354-374
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

KHCWAENPADRVSMADVLRYL
|.||...|.|| ....... |
KQCWHYDPEDRPTFSEIHEQL
Kinase F23C8.7.AA UTK 356-374 26 0.003192 6.88 In-house 278-296 (296) Show / Hide 
Range on Protein: 356-374
Range on HMM: 278-296/296
Sequence Identity: 26% (5 aa)

CWAENPADRVSMADVLRYL
||. .|..| .. |..  .
CWHYDPQERPDFEDLVQQM
Kinase F23C8.7.AA TK-Unique 354-374 33 0.008725 5.58 In-house 274-294 (294) Show / Hide 
Range on Protein: 354-374
Range on HMM: 274-294/294
Sequence Identity: 33% (7 aa)

KHCWAENPADRVSMADVLRYL
| || ..| .|.| ....  |
KSCWQWEPEERPSFRQIKHRL