Gene F16B12.7 (Nematode worm)

F16B12.7

Species: Nematode worm
Alias: aSWK272, CE09430, F16B12.7
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 14112273-14113442, WormBase Genetic Map location: X:15.72,

Classification

Group: Other
Family: Worm5

Sequence

Name Sequence Type Origin Length Description Download
F16B12.7.AA Protein Genbank 301 None Fasta, JSON
F16B12.7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 278 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of F16B12.7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F16B12.7.AA Worm5 12-268 55 2e-216 655.99 In-house 1-260 (260) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-260/260
Sequence Identity: 55% (145 aa)

YYVSYLIGEGSYGSIVAVNDMEELNKEKVIKLVKFVHGSQREKSFKTELSVFRKLDSLGNSKRNGFPQFCENFQVDG-YYAIVLSDEGDNLNDIRKRNKN
||..|..|||.||.|.|..||........||...|.||.|.|..||.||.||...|.|||..||.|||||.|||||. ||..|...|||.|||...||||
YYIIYVLGEGEYGTIYACVDMDDRHNQLAIKAMNFEHGIQCENCFKLELMVFQRIDTLGNNERNRFPQFCDNFQVDSTYYCFVMHKEGDCLNDVWMRNKN

LVFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRFKTRKRRNCID-KTYKVLLADERRCSFNIACGGDYRKSDDF
..|.||||....|..|.||.|||||||.|.|.|.||.|....|..|||.||||||..||||.|....|.| ....|...|.|.||.|..|||..||.|||
KRFSRKNVLKIMCCMSHSLQTLHSIGFIHRDCHWQNIMFAKRITPINPCKLIDFGIGKRFKNRRGHYCKDRPQRDVNFKDCRHCSWNVHCGGIPRKKDDF

ESLFYILLIDLGLSCYRE-NKAQRFLTKLKLHFATETFLQNLPWMTIVFKSMRAQNDDDF
||..|..|...|..|||. ||.|||..|.|.||..|.||.|.|||||||||||.||||||
ESMMYLALRMSGIHCYRYENKEQRFCQKMKFHFNPEQFLMNCPWMTIVFKSMRKQNDDDF
Kinase F16B12.7.AA Worm7 12-171 32 7.4e-16 49.56 In-house 1-156 (263) Show / Hide 
Range on Protein: 12-171
Range on HMM: 1-156/263
Sequence Identity: 32% (53 aa)

YYVSYLIGEGSYGSIVAVNDMEELNKEKVIKLV-KFVHGS-QREKSFKTELSVFRKLDSLGNSKRNGFPQFCENFQVDGYYAIVLSDEGDNLNDIRKRNK
|     || |..| .  | |  ..|  ...| . |.. ||  |  |.  |. .|.      |      |.    |   |.  ||.| || || |. ||| 
YKLIHKIGNGQFGEVWQVIDKQDGNVPMIVKIINKYKNGSMKRDISYDREIEFFKYCHHVPN-----IPKLFHHFTHVGWNCIVMSEEGQNLRDVVKRNN

NLVFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRFK
|  |   ||  .   .   |.  |  .| | |.| || .|     |.  . |||||   |||
NKPFSTNNVIRIAWQIGSTLCFIHNKSFIHRDVHSQNVLVTL-KNKVCKMVLIDFGNAVRFK
Kinase F16B12.7.AA CK1 12-173 19 1.5e-11 36.64 In-house 1-202 (339) Show / Hide 
Range on Protein: 12-173
Range on HMM: 1-202/339
Sequence Identity: 19% (40 aa)

YYVSYLIGEGSYG-SIVAV-----NDMEE----LNKEKVIKLVK-F----VHGSQREKSFKTELSVF---------RKLDSLGNSKRNGFPQFCENFQVD
. |  .||||..|  |  |      ||.      ..| ..|. .      ..  ..|  .. .|             |... .....  ....   . .|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

GYY-AIVLSDEGDNLNDIRK--RNKNLVFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVP------------IDKINPIKLIDFGLSK-RFK
.||  .|..  | || |.||  |. |  |. | .  ...    .|  .|..|| | |.  .|... .              .. . . .||||... ...
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

TR
..
DK
Kinase F16B12.7.AA S_TKc 12-273 14 2.9e-08 -55.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-273
Range on HMM: 1-231/231
Sequence Identity: 14% (43 aa)

YYVSYLIGEGSYGSIVAVNDMEELNKEKVIKLVKFVHGSQREKSFKTELSVFRKLDSLGNSKRNGFPQFCENFQVDGYYAIVLSDEGD---NLNDIRKRN
| .  .||.|..|.   . . .  ...  || .|        .... |... .|       .     .. . ||  ... .|.   .    .| |. |..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

KN----LVFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRFKTRKRRNCIDKTYKV--------LLADERRCSFN
.      .|.   .. . . . . |  .|| |. | ||  .|...         ||..||||....          .|. .        .|         
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----------TTFCGTPWYMAPEVL---------

IACGGDYRK-SDDFESL---FYILLIDLGLSCYRENKAQRFLTKLKLHFATETFLQNLPWMTIVFKSMRAQNDDDFN-------AEIM
      | | . |  |.   .|..|   |   ..    |. . |..    .. ... .  .  .  . |    . ..        . .
-----GYGKCKCDWWSCGCILYEMLC--GYPPFP--QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F16B12.7.AA Worm8 133-171 41 2.1e-07 17.41 In-house 116-153 (261) Show / Hide 
Range on Protein: 133-171
Range on HMM: 116-153/261
Sequence Identity: 41% (16 aa)

HSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRFK
||.|  | |    ||||     ..    |.|||.| .||
HSFGIVHGDIKADNLMVSH-SNRMFMLVLVDFGCSCWFK
Kinase F16B12.7.AA CK1-A 132-217 29 3e-07 21.46 In-house 111-196 (261) Show / Hide 
Range on Protein: 132-217
Range on HMM: 111-196/261
Sequence Identity: 29% (26 aa)

LHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRFKTRKRRNCID-KTYKVLLADERRCSFNIACGGDYRKSDDFESLFYILL
.|  .| | |.   | .. .     | . ||||||.|...  . |  |  .. | |    |  | |   | .  . ||.||. |...
VHEKNFIHRDIKPDNFLMGIGR-HCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMM
Kinase F16B12.7.AA HIPK 12-165 26 3.1e-07 18.33 In-house 1-150 (329) Show / Hide 
Range on Protein: 12-165
Range on HMM: 1-150/329
Sequence Identity: 26% (41 aa)

YYVSYLIGEGSYGSIVAVND--MEELNKEKVIKLVKFVHGSQREKSFKTELSVFRKLDSLGNSKRNGFPQFCENFQVDGYYAIVLSDEGDNLNDIRKRNK
| |  ..| | .| .|       .|.     ||. |      . .  . |.|. ..| .. |.    |  . | |.      .|      || |  | ||
YEVLEFLGRGTFGQVVKCWKRGTNEM---VAIKILK--NHPYYARQGQIEVSILHCLSQE-NADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNK

NLVFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFG
      | . ..   | . |  | ..|  ||||   |.|   |      .| ||||
FMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFG
Kinase F16B12.7.AA CK1-D 132-217 29 5.8e-07 20.44 In-house 111-196 (261) Show / Hide 
Range on Protein: 132-217
Range on HMM: 111-196/261
Sequence Identity: 29% (26 aa)

LHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRFKTRK-RRNCIDKTYKVLLADERRCSFNIACGGDYRKSDDFESLFYILL
.|.  | | |.   | .. .   . | . .|||||.||..  . ..    .  | |    |  | |   | .  . ||.||| |.|.
IHCRNFIHRDIKPDNFLMGL-GKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLM
Kinase F16B12.7.AA TTBK 92-170 25 1.6e-05 15.52 In-house 73-151 (257) Show / Hide 
Range on Protein: 92-170
Range on HMM: 73-151/257
Sequence Identity: 25% (20 aa)

IVLSDEGDNLNDIRKRNKNLVFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVPIDKINPIKLIDFGLSKRF
.|..  | || | |       |.      .|  .  |.   ||.|| | |    |  .     ... . ..||||  ..
MVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQY
Kinase F16B12.7.AA TTBKL 98-172 26 5.2e-05 12.94 In-house 83-161 (288) Show / Hide 
Range on Protein: 98-172
Range on HMM: 83-161/288
Sequence Identity: 26% (21 aa)

GDNLNDIRKRNKNL-VFNRKNVATVGCAVSRSLSTLHSIGFFHADLHEQNLMVPVPID-KIN--PIKLIDFGLSKRFKT
|.|| |.||...|  .|..  .. .|  .  .|  .|..|| | |.  .| .. .  . . .   . |||||.......
GPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAW
Kinase F16B12.7.AA STE 12-68 8 8.4e-05 13.03 In-house 1-89 (359) Show / Hide 
Range on Protein: 12-68
Range on HMM: 1-89/359
Sequence Identity: 8% (8 aa)

YYVSYLIGEGSYGSIVAVNDME-----ELNKE---------KVIKLVKFVHGS----------------QREKSFKTELSVFRKLD--S
.     ||.|..|. .   ...     . ...           || ... . .                . ..... |... .|..  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMH
Kinase F16B12.7.AA Worm8 12-59 27 0.000402 7.74 In-house 1-47 (261) Show / Hide 
Range on Protein: 12-59
Range on HMM: 1-47/261
Sequence Identity: 27% (13 aa)

YYVSYLIGEGSYGSIVAVNDMEELNKEKVIKLVKFVHGSQREKSFKTE
|    . |.|.||..    | .  |. .|.||..  |   | .. . |
YTLEKVLGRGMYGDVHLCQD-DRNNEWRVMKLIHKEHNGHRDETWRHE
Kinase F16B12.7.AA STE 145-177 16 0.063102 2.74 In-house 181-221 (359) Show / Hide 
Range on Protein: 145-177
Range on HMM: 181-221/359
Sequence Identity: 16% (8 aa)

QNLMVPVPIDKINPIKLIDFGLSKRFKT-----------------RKRRN
.| ..         .||.|||.....                    ..||
ANILL---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRN
Kinase F16B12.7.AA TTBKL 12-33 36 0.075522 2.11 In-house 1-22 (288) Show / Hide 
Range on Protein: 12-33
Range on HMM: 1-22/288
Sequence Identity: 36% (8 aa)

YYVSYLIGEGSYGSIVAVNDME
. .  .|||| .|..  | ||.
WMIVKMIGEGGFGQVYHVWDMK