Gene F16B12.5 (Nematode worm)
F16B12.5
Group:
CK1
Family:
CK1-Unique
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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F16B12.5.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 287 | Kinase domain by global Sugen HMM | Fasta, JSON |
F16B12.5.AA | Protein | Genbank | 394 | None | Fasta, JSON |
Protein domains of F16B12.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | F16B12.5.AA | CK1-Unique | 74-352 | 27 | 8.20000000001e-151 | 507.32 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 74-352 Range on HMM: 1-337/337 Sequence Identity: 27% (91 aa) VIIIKKFPAGKF--VKRVDFVNRGTIRSSSDMHCGSGIQIAIRRTEQNATILQLDLLGLNLLEYAELYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCD ...||....|.. |.||.|||.||.|...||.|....|.......|...|...........||...|.........||..|.......|.|......|. WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC IKPANFAFGLNEKKNQLNLIDFGLAESFLDDRGNHREVHNRHYRKGTYVYMSANQHHEQCFGKSFLFAFVSALLIENSAFSKKILLTIPRRKVKPNIFCS ....||.|.||||||||..|..|...............|.||.....|.||...|.|..|................|...........|.|..|....|| MMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCS NYLITGNTRRDDMESLVYSLRKILDLT--------------------------------------------------------MCWKEGRSVNNDDTHRN ........|||||||..|.|......| ||||..|..|..|.|.| CHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKLDKIIPSGIDNIIVYLRGLKFEDPVDYRQIENELRTAGKKMAPSDSSDEKMCWKGLRRQNAYDKHKN YFNLKQGNQKSCSLCGIQPINDMLQSCRMLEFKDEPN |.|.||.|.|.|..|.|.|.|||...|.|.|.....| YQNSKQFNEKPCLFCKIKPHNDMKMYCCMSEYFYMFN |
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Kinase | F16B12.5.AA | CK1 | 115-227 | 27 | 1.4e-28 | 96.8 | In-house | 98-243 (339) | Show / Hide |
Range on Protein: 115-227 Range on HMM: 98-243/339 Sequence Identity: 27% (40 aa) RTEQNATILQLDLLGLNLLEYAE---LYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGL-------------NEKKNQLNLIDFGLAE- ..... .. ..||| || .. . . ..|. .. ....| ||.. | .||.|..| ||||.||..|. |....|. .||||.| EEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARR SFLDDRGNHREVHN---------RHYRK--------G-TYVYMSANQH ..|..|..| .| | .|. | | |.| | | KYRDKDGHNR--WNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCH |
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Kinase | F16B12.5.AA | CK1-Unclassified | 151-206 | 38 | 8.1e-18 | 49.18 | In-house | 109-167 (244) | Show / Hide |
Range on Protein: 151-206 Range on HMM: 109-167/244 Sequence Identity: 38% (23 aa) LARQMIDLLHTIHDRGIVHCDIKPANFAFG-LNEKKNQLNLIDFGLAESFL--DDRGNH .| |||. . .| ....| |||| || | |. ...|. .|||||. .. | |.| IADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKH |
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Kinase | F16B12.5.AA | CK1 | 151-206 | 39 | 1.1e-17 | 57.59 | In-house | 110-167 (271) | Show / Hide |
Range on Protein: 151-206 Range on HMM: 110-167/271 Sequence Identity: 39% (23 aa) LARQMIDLLHTIHDRGIVHCDIKPANFAFGL-NEKKNQLNLIDFGLAESFLDDR-GNH .| |||. . .| ....| |||| || |. . ...|. .|||||| ..||. ..| IADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQH |
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Kinase | F16B12.5.AA | CK1-A | 116-227 | 33 | 5.7e-15 | 49.18 | In-house | 65-177 (261) | Show / Hide |
Range on Protein: 116-227 Range on HMM: 65-177/261 Sequence Identity: 33% (38 aa) TEQNATILQLDLLGLNLLEYAELYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDRG-NHREVHNRHY .|.. .. .|||| | . . . . || ||| . .| .. .| |||| || |.. |.| ||||||| . | | | . .. . CEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKN RKGTYVYMSANQH || | | | | LTGTARYASINAH |
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Kinase | F16B12.5.AA | CK1 | 279-356 | 21 | 8.6e-14 | 44.56 | In-house | 249-339 (339) | Show / Hide |
Range on Protein: 279-356 Range on HMM: 249-339/339 Sequence Identity: 21% (20 aa) TRRDDMESLVYSLRKILDLT--MCWKEGRSVNN------DDTHRNYFNLKQGNQKSCSLCGI-------QPINDMLQSCRMLEFKDEPNYEAV .||||..|. | | |. | . |. .. .. . ...... | ..... || | .... .| |...|.|.||.. GRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | F16B12.5.AA | Worm8 | 149-205 | 36 | 3.6e-13 | 34.38 | In-house | 102-158 (261) | Show / Hide |
Range on Protein: 149-205 Range on HMM: 102-158/261 Sequence Identity: 36% (21 aa) FHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDRGN .. |.. | || |||| |||. | . .| |.|||.. .| | || YQIMWQLVKILQDIHSFGIVHGDIKADNLMVSHSNRMFMLVLVDFGCSCWFKDHNGN |
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Kinase | F16B12.5.AA | Dual | 141-207 | 32 | 8.2e-13 | 39.28 | In-house | 108-175 (282) | Show / Hide |
Range on Protein: 141-207 Range on HMM: 108-175/282 Sequence Identity: 32% (22 aa) GKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLD-DRGNHR | | .. .| | ||.. . | | .| .||||||. ||... . . ||... ...| . || GQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHR |
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Kinase | F16B12.5.AA | CK1-D | 151-227 | 42 | 3e-12 | 39.36 | In-house | 100-177 (261) | Show / Hide |
Range on Protein: 151-227 Range on HMM: 100-177/261 Sequence Identity: 42% (33 aa) LARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDR-GNHREVHNRHYRKGTYVYMSANQH || ||| .. || | .| |||| || || . | ..|||||| . | | | || | | | | LADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTH |
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Kinase | F16B12.5.AA | TTBK | 141-233 | 31 | 9.4e-12 | 37.85 | In-house | 92-185 (257) | Show / Hide |
Range on Protein: 141-233 Range on HMM: 92-185/257 Sequence Identity: 31% (30 aa) GKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLN-EKKNQLNLIDFGLAESFLDDRGNHREVHNRHYRKGTYVYMSANQHHEQCFG |. . . | |... . ||. | | |||| ||| |.| .. .. ..||||| .. |. | . || | | | | . | GCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMG |
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Kinase | F16B12.5.AA | TTBKL | 162-205 | 33 | 5e-10 | 30.13 | In-house | 118-165 (288) | Show / Hide |
Range on Protein: 162-205 Range on HMM: 118-165/288 Sequence Identity: 33% (16 aa) IHDRGIVHCDIKPANFAFGLNEK----KNQLNLIDFGLAESFLDDRGN .|| |..| |.||.|...|.... . |||||.| .... |. MHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGE |
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Kinase | F16B12.5.AA | Pkinase | 133-223 | 23 | 2.2e-08 | 30.76 | Pfam | 79-179 (293) | Show / Hide |
Range on Protein: 133-223 Range on HMM: 79-179/293 Sequence Identity: 23% (26 aa) LEYA-------ELY-------GGKL--EVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQL----NLIDFGLAESFLDDRGNHREVHNR .||. .|. .|.. . |. . ..|.. | .|..||.|.|.||.|. | ..... ..|||||. | . . MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI---LIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-M HYRKGTYVYMS . . ||. ||. TTFCGTPWYMA |
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S_TKc | F16B12.5.AA | S_TKc | 66-317 | 12 | 3e-06 | -85.6 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 66-317 Range on HMM: 1-231/231 Sequence Identity: 12% (38 aa) YMTIITV------FVIIIKKFP-----AGKFVKRVDFVNRGTIRSSSDMHCGSGIQIAIRRTEQNATILQLDLLGL---NLLEYAELYGGK-----LEVP | . .. | .. | | .| . . | .. |. ... . . . ..... .|..| . .|.. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE- EAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDRGNHREVHNRHYRKGTYVYMSANQHHEQCFGK------------ .| ....|... | .|..||.|.|.||.| . .. ..||||| . . || ||. .|| HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL ------SFLFAFVSALLIENSAFSKKILLTIPRRKVKPNIFCSNYLITGNTRRDDMESLVYSLRKILDLTMCWKEG-RSVNNDDTH-------RNYF .| . . |||. ... ... ... | . . .| YEMLCGYPPFP-------QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | F16B12.5.AA | CK1 | 339-354 | 43 | 0.000214 | 11.27 | In-house | 256-271 (271) | Show / Hide |
Range on Protein: 339-354 Range on HMM: 256-271/271 Sequence Identity: 43% (7 aa) LQSCRMLEFKDEPNYE |. || |.|...|.|. LNYCRQLHFEEKPDYM |
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Kinase | F16B12.5.AA | CK1-D | 280-356 | 27 | 0.009336 | 5.36 | In-house | 184-261 (261) | Show / Hide |
Range on Protein: 280-356 Range on HMM: 184-261/261 Sequence Identity: 27% (22 aa) RRDDMESLVYSLRKILDLTMCWKEGRSVNNDDTHRNYFNLKQGNQKSCSLCGIQPIN--DMLQSCRMLEFKDEPNYEAV ||||.||| | | .. |. . .. . . |. . | || | . . . || |.| | |.| . RRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICE-KKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | F16B12.5.AA | TTBKL | 345-360 | 37 | 0.015043 | 4.51 | In-house | 273-288 (288) | Show / Hide |
Range on Protein: 345-360 Range on HMM: 273-288/288 Sequence Identity: 37% (6 aa) LEFKDEPNYEAVKQLF |...|.|.|| . ..| LRYYDRPDYEMIYECF |
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Kinase | F16B12.5.AA | CK1-A | 279-356 | 25 | 0.031261 | 3.48 | In-house | 183-261 (261) | Show / Hide |
Range on Protein: 279-356 Range on HMM: 183-261/261 Sequence Identity: 25% (20 aa) TRRDDMESLVYSLRKILDLTMCWKEGRSVNNDDTHRNYFNLKQGNQKSCSLCGIQP--INDMLQSCRMLEFKDEPNYEAV .|||||||. | . .. |. | .. |. || | ... || | |...|.| . SRRDDMESMGYVMMYFNRGKLPWQ-GMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | F16B12.5.AA | CK1-Unclassified | 280-289 | 80 | 0.042444 | 2.01 | In-house | 195-204 (244) | Show / Hide |
Range on Protein: 280-289 Range on HMM: 195-204/244 Sequence Identity: 80% (8 aa) RRDDMESLVY ||||.||| | RRDDLESLGY |
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Kinase | F16B12.5.AA | CK1 | 280-289 | 90 | 0.083161 | 2.24 | In-house | 195-204 (271) | Show / Hide |
Range on Protein: 280-289 Range on HMM: 195-204/271 Sequence Identity: 90% (9 aa) RRDDMESLVY |||||||| | RRDDMESLGY |