Gene F09G2.1 (Nematode worm)
F09G2.1
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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F09G2.1.AA | Protein | Genbank | 971 | None | Fasta, JSON |
F09G2.1.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 285 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of F09G2.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | F09G2.1.AA | KIN6 | 529-813 | 49 | 1.7e-213 | 712.26 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-305/305 Sequence Identity: 49% (152 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRA----EALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHC ..|..||||||...|.||||.|..|.....||. |...|.||.|||||||..|...|...|.|||..||.||...||||||||.|.|.|.|||.|.| IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYC CHRDLLRYVKNKK--------------CDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPS ||.|||.|..|.. |..|.||..|.....||....|||||..||..|..|..|||||||||.|.||.|.||..|.|||||....... CHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMD ENGEVTGSDR-LPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAEIE-PTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDE .........| |||||.|.|||...|||.||||||||...|||.||||||..|.. |||.|.|..||.|||.|......|..||.|||.||...||.|.| QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNE LSKLF ....| MRMQF |
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Kinase | F09G2.1.AA | TyrKc | 529-813 | 29 | 1.3e-110 | 374.66 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-280/280 Sequence Identity: 29% (93 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLG-FNEHLVNMLGCITVS-------AKSCLV .....|||.||.| |.||. ..||||| ..| ...|..|...|..|| ....|...|..| . ..| ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV LEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPS-------ENG .|...| ||. | .... . ..|..|.|.||| .||..| .|..|||||||||.|..|. .|.|||||. . . MEYMPHGDLKDYLRKHRPK-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYY EVTG--SDR--LPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAE-----IEPTELIAHLKSGARPKFPLL--------ATDKIEEIMSSCW ... . . |||.|.|.||. . .|..||||||||....|....|. | . ....|.|...|.| |.. | ..|.. .||..|| RKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCW SEKSEERPDFDELSKLF |. |.|| | |. ..| HEDPEDRPTFSEIHECF |
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Kinase | F09G2.1.AA | Pkinase_Tyr | 529-813 | 32 | 2.2e-106 | 360.92 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-270/270 Sequence Identity: 32% (95 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAA--KQEFRHEIELMKNLGFNEHLVNMLGCITVSAKS---CLVLEH .....|||.||.|.|.||. | | |....|||||. .|.. . ...| .|...||.|| ....|...|..| .. ..|.|. ITFGKKLGEGAFGEVYKGTWKG------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY CCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENG-EVTGSDRLP ..| ||| | .... . .. .. . |...||| .|| .| .|..|||||||||.|.|| .. .|..||||| . .. .. ..|. .|| MPHGDLLDYLRKHR-------EDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGLARDIYNDDYYYRKRGGGKLP IKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVP-FAEIEPTELIAHL-KSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF |||.|.||. .|. ||||||||....|....|. | .... ..|..... ..| | . | ...|.| ..| .|| .. |.|| | |. . IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | F09G2.1.AA | TK | 529-813 | 19 | 5.7e-92 | 308.56 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-486/486 Sequence Identity: 19% (93 aa) VVKNEKLGHGAYG---HVFKGKIVGVPPAIEKYNRAEA---------LDYTDCDCAVKMLPKYATDAAKQEFR----------------HEIELMKN-LG .. .|||.|..| |.||. | .| .|...... . . ...||||| . ........| .|...|.. || ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG FNEHLVNMLGCITVSAK------------SCLVLEHCCHRD----LLRYVKNKK---------------------------------------CDLEISR ...|...|..| .. ..|.|...| | |. | .... | | .. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD SVDD------TIDSHKEFLN-------------------FAWQITQGMRFLVDK------RIIHRDLAARNILITEQCGMK--------SAKVSDFG--- ..|| . ..|..|. ..||| .||..| .| ...||||||||.|..|. | .|..||| YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -----LAILSEPSENGEVTG------------------------SDRLPIKWLALECLEKAE---------FSFKSDVWSFGIVIFEMYSLGDVPFA--- || ..... ... ...|||.|.| |||.. . |. ||||||||....|....|..|.. QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM --------EIEPTELIAHLKSG--------------ARPKFPLLAT--------------DKIEEIMSSCWSEKSEERPDFDELSKLF . ...|.. .|..| |.. | ... . ....| .||... |.||.|..| . . SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | F09G2.1.AA | TK-Unique | 529-813 | 30 | 3e-71 | 243.03 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-294/294 Sequence Identity: 30% (95 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSA-KSCLVLEHCCHR .. ....| ||.|.|..|...|.. . | ..| ||||| ..||| ||.| ||..||.|| ...|..||| | | ....|.| LEVGDVIGEGAFGQVWRGEVWGIW---------KHWDKQKC-VAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG DLLRYVKNKKCD---------------LEISRSVDDTIDSHKEFLNFAWQITQGMRFLVD--KRIIHRDLAARNILITEQCGMKSAKVSDFGLAI-LSEP .|. | ...... . .. ...|.. | ...||||| .|| .| |.|.||||.|||.|.|| | .|..|||.| .. . NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISP-KDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTN SENGEVTGSDRLPIKWLALECLE--KAEF-SFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAHLKSGARPKFPLLA-TDKIEEIMSSCWSEKSEERPD .. ... |.||.|.|.| | . . . ||||||||....|. .|| |. .. ..... ... | |.. | .. . ..|.|||... ||||. GVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPS FDELSKLF |... . . FRQIKHRL |
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Kinase | F09G2.1.AA | UTK | 529-813 | 24 | 7.4e-52 | 175.69 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-296/296 Sequence Identity: 24% (77 aa) VVKNEKLGHGAYGHVFKGKIV-GVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQE----FRHEIE---LMKNLGFNEHLVNMLGCITVSAKSCLV | ..||.||.| |.|.. . ... | . . ... . |.. ..| |. | .||.. .......| | . ..| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIV LEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQ-----CGMKSAKVSDFG---LAILSE---- .|... ||. |. .. . .... . . | .||.| || .| ....||||||||.|.... | | ..|..||| .. . TEYMENGDLRSYL----RRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHC-MMVCKIADFGRGGMSRRVNTFHF ---PSENGEVTGSD--RLPIKWLALECLEKA-EFSFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAHLKSG--ARPKFPLLATDKIEEIMSSCWSEKS .| ... .. |.||.| | |.| .. |..||||||||.| .|... | .|.... .... . | .|.. | . . ..| .|| SNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDP EERPDFDELSKLF .|||||..| . . QERPDFEDLVQQM |
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Kinase | F09G2.1.AA | RTKB | 657-813 | 38 | 1.7e-51 | 171.89 | In-house | 112-264 (264) | Show / Hide |
Range on Protein: 657-813 Range on HMM: 112-264/264 Sequence Identity: 38% (61 aa) LNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWLALECLEKAEFSFKS-DVWSFGIVIFEMYSL . |. || .|| || . .|||||.|||.|.. | . |..|||.| .. . |. .||||||.| | ... .. || ||||||. .| || VDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQL---HCKICDFGMAREIDHECY--ETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIFSL GDVPFAEIEPTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF | .|... . .. .| || |. | .. .. .|| ||.. ..||||||| ..| GGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF |
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Kinase | F09G2.1.AA | Fer | 657-814 | 29 | 2.4e-49 | 166.24 | In-house | 114-283 (283) | Show / Hide |
Range on Protein: 657-814 Range on HMM: 114-283/283 Sequence Identity: 29% (50 aa) LNFAWQITQGMRFLVDKRIIHRDLAARNILITE-QCGMKSAKVSDFGLAILSEPSENGEVTG--SDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFEMY .... |. .||..| | .||||.||||.|... . | |.||||.. . .. . ....||.||| |.... ..|.|.||||||....| . IRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKK-CKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEIF SLGDVPFAE----IEPTEL----IAH-LKSGARPKFPLLATDKIEEIMS-SCWSEKSEERPDFDELSKLFA . |. |... . .|.. .. |.| ....|. . . | .|| .|| .. |.|| ..|. . . TNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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Kinase | F09G2.1.AA | Src | 572-813 | 32 | 7.3e-46 | 153.78 | In-house | 27-255 (255) | Show / Hide |
Range on Protein: 572-813 Range on HMM: 27-255/255 Sequence Identity: 32% (80 aa) AVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLV ||| | | .| . . | |...||.| |.||... . | | .| || | |. . . . .. . .|.|. .|| .| AVKTL-KPGT-MSPEAFLQEAQIMKKLRH-EKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK---------DGEGRHLHLPQLIDMAAQVAEGMAYLE DKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSE-PSENGEVTGSDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIA ...|||||||||.|. |. .|| ||||| | . .. . ..|||| | |.. |. ||||||||| . |. . | || . | . SMNYIHRDLAARNVLVGENN---VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQ HLKSGARPKFPLLATDKIEE-IMSSCWSEKSEERPDFDELSKLF ... | | | |.. | || || .. |.|| |. | . . QVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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Kinase | F09G2.1.AA | FGFR | 652-813 | 36 | 3.4e-45 | 151.96 | In-house | 134-293 (293) | Show / Hide |
Range on Protein: 652-813 Range on HMM: 134-293/293 Sequence Identity: 36% (60 aa) SHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFE . |. .|.|. .|| .| ...|||||||||.|.|. | |..||||| . |. |||||| |.| | . .|||||.|. . | TQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVM---KICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWE MYSLGDVPFAEIE-PTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF .|. |. | || . ||.| | | . . | .| .|| .|...|| | .| . IMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL |
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Kinase | F09G2.1.AA | VEGFR | 654-813 | 39 | 3.4e-45 | 156.45 | In-house | 173-332 (332) | Show / Hide |
Range on Protein: 654-813 Range on HMM: 173-332/332 Sequence Identity: 39% (65 aa) KEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLA---ILSEPSENGEVTGSD--RLPIKWLALECLEKAEFSFKSDVWSFGIV .. .... |. ||.|| . .|||||||||||..| . | .||||| | . | |. | ||||||.|.| . .. .|||||.|.. EDLICYSFQVARGMEFLASRKCIHRDLAARNILLCEN---NVVKICDFGLARHGIYKDPD---YVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVF IFEMYSLGDVPFAEIE-PTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLF |. ||| .| . |.. ||.| | . | ..| | .|| .||.. |||| |.|| . . LWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL |
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Kinase | F09G2.1.AA | EGFR | 572-814 | 33 | 8.4e-43 | 139.83 | In-house | 32-258 (258) | Show / Hide |
Range on Protein: 572-814 Range on HMM: 32-258/258 Sequence Identity: 33% (82 aa) AVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCCHRDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLV |.|.| . |..|. | | . ..||| .|| | || . || ||.. | |.| |. . ||.. || .|| .| AIKVLREQTGPKANEEMLDEAYVMASVD-HPHLVRLLGVCMHSQ-MQLVTQYMPYGCLLDYVRQHK----------DNIGSQ-HLLNWCVQIAKGMQYLE DKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWLALECLEKAEFSFKSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAH ..|..||||||||.|. . |. ||||| | |. |. . ..||||.||||... . .|||||.|. . |. | |.. |. | EHRMVHRDLAARNVLVKS---PNHVKITDFGLAKLLEHDEKEYHAQGGKMPIKWMALECIHHRCYTHQSDVWSYGVTCWELMTFGQKPYDGIPAREIPDL LKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSKLFA |. | | . | | . .| .|| .. || | || . | LEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK |
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Kinase | F09G2.1.AA | S_TKc | 529-815 | 19 | 8.6e-31 | 109.53 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 529-815 Range on HMM: 1-231/231 Sequence Identity: 19% (58 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCCH-- . .|.|.||.| |.|.. .. |. .|.|... . .| ||...|. ...|...... . ..|.|.| . YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDL RDLLRYVKNKKCDLEISRSVDDTIDSHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGMKSAKVSDFGLAILSEPSENGEVTGSDRLPIKWL ||..| |.... . . . ...|| ... .. ...|||||| |||..| |..||||| . . .. GDLFDYIKKRGRHGL------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYM ALECLEKAEFSF-KSDVWSFGIVIFEMYSLGDVPFAEIEPTELIAHLKSGARPKFPLLATDKIEEIMSSCWSEKSEERPDFDELSK-------LFAT | | | ... |.|.||.|....||.. | || .. ... ... .. .... |. |.|| |. . APEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | F09G2.1.AA | Pkinase | 529-813 | 20 | 1.9e-25 | 91.09 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 529-813 Range on HMM: 1-293/293 Sequence Identity: 20% (66 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAK-QEFRH--EIELMKNLGFNEHLVNMLGCITVSAKSCLVLEHCC .. .|.| |..| |.|.. .| . ||| ..| .. | |. |. ||..||.|. .. | .... . . . ..|.|.| YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKDHIYMVMEYCE HR----DLLRYVKNKKCDLEISRSVDDTID--SHKEFLNFAWQITQGMRFLVDKRIIHRDLAARNILITEQCGM-KSAKVSDFGLAI---LSEPSENGEV . || .|.. ... | .| ....|| .|. .. ...|||||| |||| ... . |..||||| . | . . GGLYVMDLFDYIST----------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF TGSDRLPIKWLALECLE-KAEFSFKSDVWSFGIVIFEMYSLGDVPFAEI----EPTELIAHLKSGAR--PKFPLLAT---------------------DK .|. . ..| | . . . |.|.||.|....||.. | || . . . .. .. . ..|. . . CGTPW----YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE IEEIMSSCWSEKSEERPDFDELSKL--F .....|. . ..|| .... . | CKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | F09G2.1.AA | RTKB | 529-609 | 29 | 8.9e-09 | 25.74 | In-house | 1-69 (264) | Show / Hide |
Range on Protein: 529-609 Range on HMM: 1-69/264 Sequence Identity: 29% (24 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLG | ||||.||.| ||.. . .. .| ||.| |. | ..|.|. |. .|| || ... ..| VWLGEKLGNGAFGEVFQAWV------------RNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIG |
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Kinase | F09G2.1.AA | Fer | 529-598 | 26 | 7.8e-07 | 19.43 | In-house | 1-66 (283) | Show / Hide |
Range on Protein: 529-598 Range on HMM: 1-66/283 Sequence Identity: 26% (21 aa) VVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTD-------CDCAVKML-PKYATDAAKQEFRHEIELMKN-L |. ..||| ||.| |.||. | . . . ....||.. ||.. ..|| || .|.| . VTLGKKLGEGAFGEVYKGR------------R-TLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNY |
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Kinase | F09G2.1.AA | FGFR | 528-610 | 27 | 0.000115 | 11.77 | In-house | 1-73 (293) | Show / Hide |
Range on Protein: 528-610 Range on HMM: 1-73/293 Sequence Identity: 27% (23 aa) LVVKNEKLGHGAYGHVFKGKIVGVPPAIEKYNRAEALDYTDCDCAVKMLPKYATDAAKQEFRHEIELMKNLGFNEHLVNMLGC |.. . || |..| | .. .|.... .. . . ||||| . .|| |.| || | .. .| ||| LTL-GKMLGEGCFGQVWMAEAKGIDCDRPEKEIT---------VAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGC |
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Kinase | F09G2.1.AA | EGFR | 529-546 | 50 | 0.000915 | 8.18 | In-house | 1-18 (258) | Show / Hide |
Range on Protein: 529-546 Range on HMM: 1-18/258 Sequence Identity: 50% (9 aa) VVKNEKLGHGAYGHVFKG . | .|| ||.| |.|| LKKVKVLGSGAFGTVYKG |
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Kinase | F09G2.1.AA | Src | 529-547 | 36 | 0.038658 | 3.01 | In-house | 1-19 (255) | Show / Hide |
Range on Protein: 529-547 Range on HMM: 1-19/255 Sequence Identity: 36% (7 aa) VVKNEKLGHGAYGHVFKGK . .||| | .| |..|. IKLCRKLGQGQFGEVWMGY |
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Kinase | F09G2.1.AA | VEGFR | 572-636 | 34 | 0.07686 | 2.97 | In-house | 33-100 (332) | Show / Hide |
Range on Protein: 572-636 Range on HMM: 33-100/332 Sequence Identity: 34% (24 aa) AVKMLPKYATDAAKQEFRHEIELMKNLGFNEHL--VNMLGCITV--SAKSCLV-LEHCCHRDLLRYVKNK ||||| || . . |..... .| || ||.||| | . .| | ||. |. | . | AVKMLKEGATASEHRALMSELKMLIHIG--HHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK |