Gene D2023.6 (Nematode worm)

D2023.6

Species: Nematode worm
Alias: D2023.6, D2023.6ABC1-family, aSWK432, CE09076
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 11829792-11831953, WormBase Genetic Map location: V:3.4,

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-B

Sequence

Name Sequence Type Origin Length Description Download
D2023.6.AA Protein Genbank 512 None Fasta, JSON
D2023.6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 292 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of D2023.6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase D2023.6.AA ABC1-B 142-259 51 3.5e-74 252.74 In-house 1-125 (125) Show / Hide 
Range on Protein: 142-259
Range on HMM: 1-125/125
Sequence Identity: 51% (66 aa)

SELNAKVGDLFSEFSEKPVGAASLAQVHKAKLKESGETVAVKVQHKRVYKNSRTDVNTMEFLVKVADAVFP------EFRLMWLVDEIKKNLPNELDFLH
. |  .. | ||||..||..||||||||.|||.. ||||||||||....|....|...||..|||.|..||      ||..||..|||.||||.||||..
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHD-GETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYN

EAKNADEAAQRFK---HLKFLRIPKIK
||.||....|.||   |..||..|.|.
EARNAEKCRQMFKKFKHFDFLYVPRIH
Kinase D2023.6.AA ABC1 142-259 50 5.4e-65 222.25 In-house 1-123 (123) Show / Hide 
Range on Protein: 142-259
Range on HMM: 1-123/123
Sequence Identity: 50% (63 aa)

SELNAKVGDLFSEFSEKPVGAASLAQVHKAKLKESGETVAVKVQHKRVYKNSRTDVNTMEFLVKVADAVFP-----EFRLMWLVDEIKKNLPNELDFLHE
..|  .  | ||||.|||..|||.||||.||||. |.||||||||..|......|.|.||..||..|..||     .|.|||.|||..|.||.|.||..|
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKD-GQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNE

AKNADEAAQRFK--HLKFLRIPKIK
|.||....|.||  | .|...|.|.
ARNAEKCRQLFKKFHWPFFYVPRIH
Kinase D2023.6.AA ABC1 142-259 43 1.8e-60 205.61 Pfam 1-126 (126) Show / Hide 
Range on Protein: 142-259
Range on HMM: 1-126/126
Sequence Identity: 43% (55 aa)

SELNAKVGDLFSEFSEKPVGAASLAQVHKAKLKESGETVAVKVQHKRVYKNSRTDVNTMEFLVKVADAVFPE-----FRLMWLVDEIKKNLPNELDFLHE
.||.... ..|.||.|.|..|||.||||.|.|| .||.|||||||  | |... |...|....|... .||.     |.|||.|||..|||| |||...|
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

AKNADEAAQRFKHL---KFLRIPKIK
|||... ...|.|.   .....||. 
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase D2023.6.AA ABC1-A 155-185 54 3.8e-09 28.06 In-house 1-30 (216) Show / Hide 
Range on Protein: 155-185
Range on HMM: 1-30/216
Sequence Identity: 54% (17 aa)

FSEKPVGAASLAQVHKAKLKESGETVAVKVQ
| |.|  .||  |||.| || .|  ||||.|
FEEMPFACASIGQVHQAVLK-DGREVAVKIQ
Kinase D2023.6.AA S_TKc 154-444 12 0.000166 -110.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 154-444
Range on HMM: 1-231/231
Sequence Identity: 12% (41 aa)

EFSEKPVGAASLAQVHKAKLKESGETVAVKVQHKRVYKNSRTDVNTMEFLVKVADAVFPEFRLMWLVDEIKKNLPNELDFLHEAKNADEAAQRFKHLKFL
    ...|  . ..|.|.. |..|. ||.|. .                                      ... .|.. |..           .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------------EHIRREIQILKK-----------HHPNIV

RIPKIKYDLTTTRVLTMEFCEG--AHVDDVEYLKKNN-------IDPHDVCMKIGKTISEMIFL--QGYLHSDPHPGNVLINSLGNGKYEIVLLDHGLYL
..  . .|  .   . ||.|.|    . |  |.||..       ... ...  .  ... . ..  .| .| |  | |.|...      .| . | ||  
KLYDVFQD--DHLYMVMEYCDGDLGDLFD--YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLAR

NISDHIRKLYSDLWLA--ILKPDLQEIRKVASQMGVGELYGL-----------FACMVTRRS-WKSVTGGIGKSKMNESEKDELRMYASSLIPQISEV--
 .        .  ..|  .|                   ||            .. |....  .      . |  .           | ..| .. ..  
QL---TTFCGTPWYMAPEVL------------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------SPEAKDFIRKCLQKDP

LARMPREMLLI----LKTNDLM
  |.    .|      |    .
EKRPTA-EALQDEWDIKCHPWF
Kinase D2023.6.AA ABC1-A 252-282 35 0.000321 10.81 In-house 97-127 (216) Show / Hide 
Range on Protein: 252-282
Range on HMM: 97-127/216
Sequence Identity: 35% (11 aa)

FLRIPKIKYDLTTTRVLTMEFCEGAHVDDVE
| ..|..   ..|.||||||  .|  .|  .
FFYVPHVIDEYCTDRVLTMELMYGFPIDQCQ
Kinase D2023.6.AA CDK7 156-183 35 0.000696 5.75 In-house 3-30 (288) Show / Hide 
Range on Protein: 156-183
Range on HMM: 3-30/288
Sequence Identity: 35% (10 aa)

SEKPVGAASLAQVHKAKLKESGETVAVK
 .| .|.   | | ||  ...|. ||.|
KIKHIGEGQFATVYKACDHQTGQIVAIK