Gene ckk-1 (Nematode worm)
ckk-1
Sequence
Protein domains of ckk-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | ckk-1.AA | Meta | 21-302 | 67 | 3e-264 | 772.3 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-287/287 Sequence Identity: 67% (195 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAA-PSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPNDNYLY ||||||||.||||.|||||||||...||.|.|.|.||||.....|.||||.||.|.. ....||||..|..||||||||.|||||||||||||||..||| YRLMEEIGKGSYGVVKLAYNEEDHHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDYLY MVFEFVEKGSILEIPTDKPLDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVSCEFEGIDAFLSG--TAGTPAFMAPEALTEG ||||.||||...|.|.|.||.||.|||||||..|||||||||||.|||||||||||.|.|.|||||||||.||||.||||.. ||||||||||||..|. MVFEYVEKGPVMEVPCDNPLSEDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEACSEE ANHFYSGRAQDIWSLGITLYAFVIGTVPFVD--NYIIALHKKIKNDPIVFPEAPILSEALQDIILGMLKKDPGHRLMLHEVKVHTWV .||||.|||.|.|..|.|||.||.|..||.| |||..||.||||.|..|||.|..||.|.|.|..||.|.|.||.|..|.|.|.|| QNHFYCGRALDVWAMGVTLYCFVFGQCPFIDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV |
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Kinase | ckk-1.AA | CAMKK | 21-302 | 39 | 2.8e-185 | 593.49 | In-house | 1-396 (396) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-396/396 Sequence Identity: 39% (155 aa) YRLMEEIGQGSYGIVKLAYNEED-KNLYALKVLDK----MKLLKNFACFRQPPPRRNKENAAPS-VLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPN |.||.|||||..|.|||||||.| ...|| |...| .||.|.. ..|.||.|....|.... ..||...|..||||.||. |||.|||.||.|||. YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ DNYLYMV-FEFVEKGSILEIPTDKP--------------------------LDEDT---------------------AWSYFRDTLCGLEYLH-YQK--- ....||| .|..|.|.|...|..|. ..|. ||.|||| ..|||||| ||| NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS ----------------IVHRDIKPSNLLLSDIG---QVKIADFGVSCEFEGIDAFLSG-----------TAGTPAFMAPEALTEGANHF----------- |.||||||.|.|....| .|||||||||..|||.|..||. |||||||||||..... ... YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF -YSGRAQDIWSLGITLYAFVIGTVPFVDNYIIALHK---KIKNDPIVFPE-----------APILSEALQDIILGMLKKDPGHRLMLHEVKVHTWV |.|.|.|||.||.|||.|| |..||..|....||. |||||||.||| .| .|| |.|.|..||.|.| .|......|||.|| IYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV |
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Kinase | ckk-1.AA | S_TKc | 21-302 | 27 | 5.8e-92 | 312.73 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-231/231 Sequence Identity: 27% (82 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPNDNYLYM |.....||.|..| |..... ... ..|.|... . ...||.|||| |||.||| .| .| ..||| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYM VFEFVEK--GSILEIPTDKP-------LDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVSCEFEGIDAFLSGTAGTPAFMAP |.|... |. ... ... ..| .|..|.. ..|.|||.| ..|.|||.||.|.||.. ..||.|||..... . ||| .||| VMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAP EALTEGANHFYSGRAQDIWSLGITLYAFVIGTVPFVDNYIIALHKKIKNDPIVFPEAPILSEALQDIILGMLKKDPGHRLMLHEVKV-------HTWV | | |.... |.||.|..|| .. | || . .. |||. |. . |.| ..|.||| .|. |. | |. EVL------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | ckk-1.AA | CAMKL | 21-302 | 30 | 1.9e-88 | 282.33 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-297/297 Sequence Identity: 30% (96 aa) YRLMEEIGQGSYGIVKLAYN-EEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNPLQL-VQKEIAILKKLS---HPNVVKLVEVLDDPND ||. ...|.||.| |||| . . .| |..|| |. .. . . ... .| . . ...||.|.|.|. |||..|| ||...|. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCG--QKH---------ESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEH ----NYLYMVFEFVEKGS--ILEIPTDKP-----LDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIG--QVKIADFGVSCEFEGI----DAF ...|.| | .. |. .. .. ..|. | ||| .....|.| ..|||||||| |.||.. | ..||.||| | ... . . . DIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQK LSGTAGTPAFMAPEALTEGANHFYSGRAQDIWSLGITLYAFVIGTVPFVDNYII-------ALHKKIKNDPIVFPEAPILSEALQDIILGMLKKDPGHRL |. |.|..|||| . .|.| | |.. ||||.|..||| | |..|| | . |..||. . .| . .| ..|.| .||...| .| LKTFCGSPPYMAPE-IFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP MLHEVKVHTWV .|... | |. TIHQIMNHPWM |
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Kinase | ckk-1.AA | CAMK | 26-302 | 21 | 2.5e-77 | 248.58 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 26-302 Range on HMM: 1-425/425 Sequence Identity: 21% (94 aa) EIGQGSYGIVKLAYNEEDK------------NLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNP-------------LQLVQKEIAILKKLS- ..|.||.|.|||... ... .| |..|| || .. . . | . ... .. |..||.|.|||. TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDY-S----N----C-YKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQG ------HPNVVKLVEVLDDPN-----------------DNYLYMVF---EFVEKG----SILEIPTDK----------------PLDEDTAWSYFRDTLC |||..|| || .||. |...|||. |... | ... ... ..|. | ||| .. IGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICS GLEYLHYQKIVHRDIKPSNLLLSDI-----------------GQVKIADFGVSCEFEGI-----------------------DAFLSGTAGTPAFMA-PE ...|.| ..|||||.|| |.||.| ...||.||| ...|.. . .. |||..|| || AVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE ALTE----------GANHFYSGRAQDIWSLGITLYAFVIGTVPFVDN-------------YIIALHKKIKNDPIVFPEAPI------------------- | .. | |.. |.||.|. ||. . |. || . . |..||.. ||. .. VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF ---LSEALQDIILGMLKKDPGHRLMLHEVKVHTWV .|. .| | .||..|| .|. ..... | |. HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | ckk-1.AA | Pkinase | 21-302 | 25 | 2.1e-72 | 251.65 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-293/293 Sequence Identity: 25% (82 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNF---ACFRQPPPRRNKENAAPSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPNDNY |.. . ||.||.| |..... . ..|.|...| . ... . . ||.|.|.|.|||.|.| .. | ... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL------------------------SEIQIMKRLNHPNIVRLYDWFED--KDH LYMVFEFVEKG----SILEIPT---DKPL--DEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQV----KIADFGVSCEF-EGIDAFLSGTA .|||.|..|.| . .. . .... .|... .|.. .|.||||.| ..|.|||.||.|.|... |.. ||.|||... | . . ... . IYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC GTPAFMAPEALTEGANHFYSGRAQDIWSLGITLYAFVIGTVPFVDN------YIIALHKKIKNDPIVFPEAPILS-------------------EALQDI ||| .|||| . . | |.. |.||.|..|| .. | || . ......|. |. |.. | |...|. GTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF ILGMLKKDPGHRLMLHEVKVHTWV | ..|.||| |. .... | |. IKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | ckk-1.AA | LKB | 88-302 | 35 | 1.6e-66 | 196.51 | In-house | 47-265 (265) | Show / Hide |
Range on Protein: 88-302 Range on HMM: 47-265/265 Sequence Identity: 35% (77 aa) VQKEIAILKKLSHPNVVKLVEVLDDPNDNYLYMVFEFVEKG---SILEIPTDKPLDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIA |.|||.|||.. |..|..|..|. . .|||.|.. | .|. .| . | ||.. |.|||| |..||.||||.||||. . .|| VKKEIQILKRMHHRHVIQLIDVFYNEEKQKMYMVMEYCVCGTMQEMLDMQPCKRMPIWQAHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKIC DFGVSCEFEGIDAF--LSGTAGTPAFMAPEALTEGANHFYSGRAQDIWSLGITLYAFVIGTVPFVDNYIIALHKKIKNDPIVFPEAPILSEALQDIILGM |||| . . .. .. |.||| || .. | ..|| |||| |.||| ..| || . | | .. .| . ||. | || DFGVAEQLHHFQRDDCCTTSQGSPAFQPPE-CANGNHDTFSGFKVDIWSMGVTLYNMTTGKYPFEGDNMYKLFENIGKCQWEMPCWYDCDKDLQNLIKGM LKKDPGHRLMLHEVKVHTWV | .|. |. .|... |.|. LQYDHNKRFSCHQIMHHPWF |
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Kinase | ckk-1.AA | Ciliate-E2 | 21-302 | 22 | 3.1e-62 | 212.41 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-365/365 Sequence Identity: 22% (88 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNPLQLVQKEIAILK----------------KLSHPNVV | . . ||||..|.|... . ......|.|. | |. . | . .|. | .. | .. . .|| |.. .|.|||.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQM--Q-EKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNII KLVEVLDDPNDNYLYMVFEFVEKGSILE--------------IPTDKPLDEDTAWSYFRDTLC---------------GLEYLHYQK-IVHRDIKPSNLL |..|. . .||..|.|.|... |. .. . |...| . ... | .||||| .. |.||||||.|.| KMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL LSDIGQVKIADFGV------------------SCEFEG--------------IDAFLSGTAGTPAFMAPEALTEGA-----NHFYSGRAQDIWSLGITLY . .||.||| . | . .. ..||| .|||| | . .. . . . ||||||..|| F-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY AFVIGTVPFVDNYIIALHKKIKNDPIVFPEA----------------PILSEALQDIILG----MLKKDPGHRLM-LHEVKVHTWV .. | || ..||. .| ||.. .|. .|.| ||.||| |. ... | | EMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | ckk-1.AA | Ciliate-E2-Unclassified | 21-302 | 23 | 2.5e-59 | 203.42 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 21-302 Range on HMM: 1-352/352 Sequence Identity: 23% (91 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLY-----ALKVLDKMKLLKNF--------------------ACFRQPPPRRNKENAAPSVLRNPLQLVQKEIA-I |.. . ||||..|.|........| .| . |. ......... .|. | YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRK------------------------Y-NKIMQQI LKKLSHPNVVKLVEVLDDPNDNYLYMVFEFVEKGSILEIPTD------------------KPLDEDTAW-----SYFRDTLCGLEYLHYQK-IVHRDIKP |. . ||..||.... | ....|.| |..| |. ... .. | ..| | ||. |.||||||... |.|||||| LLNHPHPFIVKMFYCFQD--KQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKP SNLLLSDIG---QVKIADFGVSC---EFEGIDAF-------------LSGTAGTPAFM----APEALTEGANH---FYSGRAQDIWSLGITLYAFVIGTV .|.|... | ..||.||| | .....| . .. ..||| .| ||| | . . . . ||||||. ||... |. ENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYY PFVDNYIIA----------------LHKKIKNDPIVFPEAP------ILSEALQDIIL----GMLKKDPGHRLMLHEVKVHTWV || || . |...||. .| ||..| ..|. .|.| ||||.|. |. . ... | | PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | ckk-1.AA | CAMKK-Unclassified | 137-302 | 28 | 5.2e-57 | 184.13 | In-house | 173-392 (392) | Show / Hide |
Range on Protein: 137-302 Range on HMM: 173-392/392 Sequence Identity: 28% (63 aa) KPLDEDTAWSYFRDTLCGLEYLHYQK---------------------IVHRDIKPSNLLLSDIGQ-----VKIADFGVSCEFEGIDAF-LSGTAGTPAFM . ..|. . .|||. . || |.| .. |.|||||| |.|...... .||||||.| .|. . |...|||..|| YKMHEQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFM APEALTEG-ANHFYSG------------------------RAQDIWSLGITLYAFVIGTVPFVDNYIIALHK-KIKNDPIVFPE--APILSEALQDIILG |||... . |.. .| ||||||.|.|..| ...|| . . | . .|... |.|| | .|. ..| | . APEFWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKA-DIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQK MLKKDPGHRLMLHEVKVHTWV |..|.| |. . . || |. MCDKNPKKRITIDQMLVHPWF |
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Kinase | ckk-1.AA | ULK | 85-302 | 29 | 3.4e-55 | 189.7 | In-house | 54-329 (329) | Show / Hide |
Range on Protein: 85-302 Range on HMM: 54-329/329 Sequence Identity: 29% (82 aa) LQLVQKEIAILKKLS--------HPNVVKLVEVLDDPNDNYLYMVFEFVEKGSIL-EIPTDKPLDEDT----------AWSYFRDTLCGLEYLHYQKIVH .||...|| |.||| |||.||| ... ..|.|..|...|. . | | ..|.| ||| | ..|.. | |. .|| ..|.| WQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIH RDIKPSNLLLSD------------IGQVKIADFGVSCEFEGI---DAFLSGTA------GTPAFMAPEALTEG--ANHFYSGRAQDIWSLGITLYAFVIG |||||.| |... .|..|||||| . .. .. . . ||| .|||. | . ..|. . ||||||. .| . | RDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKC-DIWSLGCIFYEMLYG TVPFVDNYIIALH-----KK----------IKNDPIVFP---EAPILSEALQDIILGMLKKDPGHRLMLHEVKVHTWV .||. . . . | ||. |. || ..|..|. ..|.| .||..|. | .|. | |. KPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | ckk-1.AA | ULK | 85-302 | 31 | 5.8e-53 | 182.28 | In-house | 54-324 (324) | Show / Hide |
Range on Protein: 85-302 Range on HMM: 54-324/324 Sequence Identity: 31% (86 aa) LQLVQKEIAILKKLS---HPN--VVKLVEVLDDPNDNYLYMVFEFVEKGSIL-EIPTDKPLDEDT----------AWSYFRDTLCGLEYLHYQKIVHRDI .|| ..|| |.||| ||| .||| ... ..|.|..|...|. . | | ..|.| | | | ..|.. . |. .|| ..|.|||| WQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDI KPSNLLLSD------------IGQVKIADFGVSCEFEG--IDAFLS-GTA------GTPAFMAPEALT-EGANHFYSGRAQDIWSLGITLYAFVIGTVP- ||.|.|... .|..|||||| . .. .... . ||| .|||. | .|.. |. ||||||. .| . | .| KPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF ---FVDNY--IIALHKK-------IKNDPIVFP---EAPILSEALQDIILGMLKKDPGHRLMLHEVKVHTWV | | | |. | .. ||| || || ..|..|. ..|.| .||..|. | .|. | |. FSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | ckk-1.AA | CAMKK-Unclassified | 21-132 | 38 | 1.6e-29 | 93.1 | In-house | 1-111 (392) | Show / Hide |
Range on Protein: 21-132 Range on HMM: 1-111/392 Sequence Identity: 38% (46 aa) YRLMEEIGQGSYGIVKLAYNEED-----KNLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPND | . ...|.||.| |||| .. . . .| || | || | . || . ..| |.|||.|||| ||| |||..|| || ||| . YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIY--------NDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDN NYLYM--VFEFVEKGSILE . .|| | |....|.|.. DKIYMGQVMEYCQMGQIMS |
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Kinase | ckk-1.AA | TyrKc | 21-301 | 20 | 1.5e-14 | 12.41 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 21-301 Range on HMM: 1-280/280 Sequence Identity: 20% (64 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLKNFACFRQPPPRRNKENAAPSVLRNPLQLVQKEIAILKKL--SHPNVVKLVEVLDDP----- .| ...| | .|.| .. ..| | ||. | .. .|. |..|| .|||.|.|. | .. ITLGKKLGEGAFGEVYKGTWK-------IQVA--VKMLKEDA----------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFM NDNYLYMVFEFVEKGSILEIPTDKP--LDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVSCEFEGI-------DAFLS---- . |..|.|....|. .. .. | .. |. . || |||| ....|||. | |... ..|||.||| | . . | . YIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHK GTA--GTPAFMAPEALTEGANHFYSGRAQDIWSLGITLY-AFVIGTVPFVD-----NYIIALHKKIKNDPIVFPEAP-------ILSEALQDIILGMLKK |. ||||.. |. . |.|| |.... | | | . . .....|. . . . .... .|.. . GGKTMLPIRWMAPECI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE DPGHRLMLHEVKVHTW || | |. .. . DPEDRPTFSEI-HECF |
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Kinase | ckk-1.AA | ULK | 21-60 | 31 | 2.7e-07 | 22.01 | In-house | 1-44 (324) | Show / Hide |
Range on Protein: 21-60 Range on HMM: 1-44/324 Sequence Identity: 31% (14 aa) YRLMEEIGQGSYG-IVKLAYNEED---KNLYALKVLDKMKLLKN | | ...|.||.| | ..|... . ..| |. || |. |. YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKK |
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Kinase | ckk-1.AA | Pkinase_Tyr | 90-132 | 34 | 2e-06 | 22.56 | Pfam | 52-96 (270) | Show / Hide |
Range on Protein: 90-132 Range on HMM: 52-96/270 Sequence Identity: 34% (16 aa) KEIAILKKL-SHPNVVKL---VEVLDDPNDNYLYMVFEFVEKGSILE .|..|.|.| .|||.|.| . ..|| ..|.|.|....|. |. REAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLD |
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Kinase | ckk-1.AA | ULK | 21-60 | 31 | 4e-06 | 17.39 | In-house | 1-44 (329) | Show / Hide |
Range on Protein: 21-60 Range on HMM: 1-44/329 Sequence Identity: 31% (14 aa) YRLMEEIGQGSYGIVKLAYNEEDK----NLYALKVLDKMKLLKN | | ...|.||.| | ..|...| ..| |..|| |. .. YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQK |
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Kinase | ckk-1.AA | Pkinase_Tyr | 153-189 | 40 | 5.4e-05 | 17.55 | Pfam | 122-158 (270) | Show / Hide |
Range on Protein: 153-189 Range on HMM: 122-158/270 Sequence Identity: 40% (15 aa) CGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVS .|.|||. ....|||. | |... ..|||.||| . KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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Kinase | ckk-1.AA | LKB | 21-59 | 33 | 0.001723 | 6.29 | In-house | 1-39 (265) | Show / Hide |
Range on Protein: 21-59 Range on HMM: 1-39/265 Sequence Identity: 33% (13 aa) YRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLDKMKLLK | . . .| |||| || . . . | |.. | || . YMMGDVLGEGSYGKVKECMDSYTLCRRAVKIMKKKKLRR |
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Kinase | ckk-1.AA | Pkinase_Tyr | 21-39 | 21 | 0.137705 | 6.0 | Pfam | 1-19 (270) | Show / Hide |
Range on Protein: 21-39 Range on HMM: 1-19/270 Sequence Identity: 21% (4 aa) YRLMEEIGQGSYGIVKLAY ......|.|..| |.... ITFGKKLGEGAFGEVYKGT |