Gene C47D12.1 (Nematode worm)

C47D12.1

Species: Nematode worm
Alias: C47D12.1, CE05429, aSWK448
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 11675752-11661479, WormBase Genetic Map location: II:3.92,

Classification

Group: Atypical
Family: PIKK
Subfamily: TRRAP

Sequence

Name Sequence Type Origin Length Description Download
C47D12.1.AA Protein Genbank 3944 None Fasta, JSON

Protein domain

Protein domains of C47D12.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C47D12.1.AA PI3Kc 3594-3937 15 6.3e-69 236.22 SMART 1-336 (336) Show / Hide 
Range on Protein: 3594-3937
Range on HMM: 1-336/336
Sequence Identity: 15% (54 aa)

AFYLKKSVQDEPTNRVPQMFKHLDHVLQTDRESARRHLHAPTVLQMRVGQKTTLYEVASVQPYAMPPDCTRNYPASQIDIVHPYDVLTATFNGSYYPDDM
|...|.  .    .|. |||.. ....|.|.|..||.||. .   . .|.|. ..|. .  .....  .............|                  
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYH----------------QW

VLHFFERFAQSSSSIGQPLPTPTNQDGTVAPPRLTEAHHIKNIIYEDFARDMIPFRLLYDYLTARYPDP-VMYYAMKKQLLHSLAVLSTIEYHCNLTPMG
.    .  .... . ... .....|........ ....|.....|...|....... |||... ..|||  ........  .|.|. . . |....  . 
FMFDML-VPEIQ-K-NMY-MMIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRH

PDQMMMTMNTGVLSNPSYRFEIRGGRSLHDIQHFGH--EVPFRLTPNLSILVG----VAQDGDLLWSMAAASKCLMKKEPEVIMRPLVWDEFANN-TDCD
.|..|..|.|| .  ... .    |.... ..|. |   ||||||...  . |    ....... ....    ..|.|....||  . .   ...  ...
NDNIMLDMKTGHCFHIDFGHIFGHGPKKPGFKHH-HRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWR

KSVFACHASNSYINGV-ASKLRNTNSADA----KLRKDDCVSLISRAKDSDNLARMP
..  ...  .....    |.   .. ...    || .... |...|....... ...
MMEKDIKYLRQRFRLDHLSDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase C47D12.1.AA TRRAP 3563-3591 48 2.2e-05 16.84 In-house 1-29 (46) Show / Hide 
Range on Protein: 3563-3591
Range on HMM: 1-29/46
Sequence Identity: 48% (14 aa)

LSRFEPNFEIVIKGGQVIRKIYIRGQTGK
. || |  ||| |     |..||||  ||
IARFMPRVEIVQKHNTAARRLYIRGHNGK
Kinase C47D12.1.AA PIKK 3563-3635 36 0.000534 10.88 In-house 1-73 (290) Show / Hide 
Range on Protein: 3563-3635
Range on HMM: 1-73/290
Sequence Identity: 36% (28 aa)

LSRFEPNFEIVIKGGQVIRKIYIRGQTGKSAAFYLK---KSVQDEPTNRVPQMFKHLDHVLQTDRESARRHLHAPT
  || .  ..|..  |  .||||||  ||.  . .|    . ||.   || | |  .   ||.| |. .||||..|
RIRFMDRMVTVMAHKQKPKKIYIRGHDGKEYPYLCKGHEDLRQDQ---RVMQLFQLMNTCLQKDPECQKRHLHIRT
Kinase C47D12.1.AA PIKK 3830-3839 70 0.182052 1.56 In-house 244-253 (290) Show / Hide 
Range on Protein: 3830-3839
Range on HMM: 244-253/290
Sequence Identity: 70% (7 aa)

VPFRLTPNLS
||||||.|..
VPFRLTRNMV