Gene C25F6.4 (Nematode worm)

C25F6.4

Species: Nematode worm
Alias: CE27088, C25F6.4, aSWK333
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 5430364-5435344, WormBase Genetic Map location: X:-5.01,

Classification

Group: TK
Family: DDR

Sequence

Name Sequence Type Origin Length Description Download
C25F6.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 247 Kinase domain by global Sugen HMM Fasta, JSON
C25F6.4.AA Protein Genbank 767 None Fasta, JSON

Protein domain

Protein domains of C25F6.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
F5_F8_type_C C25F6.4.AA F5_F8_type_C 40-177 27 2e-30 106.74 Pfam 1-140 (140) Show / Hide 
Range on Protein: 40-177
Range on HMM: 1-140/140
Sequence Identity: 27% (41 aa)

QITASSSFDKQSVGP--QNARLHSE--LASGAWCP-KPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLRPG--S-QWIRYKNRT
||||||... .  ..    ....    .  ..|.. |.. |..  ...|| |. .  ||.|..|.|...|.  .... | | |   |  . .|. ||. .
QITASSQWSGYWGNGWPPDNAIDGNGYPN-TFWHSQKWS-NNDDPQWIQVDLGKPYKITGVVYQWRQDGGN--GWVKKYKIQYSNDGGDESNWTTYKDHD

GHVYMDGNFDTTTPVIRVLDPPIVASRIRFVPS-SKNTRTVCMRAEI
|   ..|| | . || ....|||.|  .|..|   .|.   .||.|.
G-KVFYGN-DND-PVKNMFFPPIKARYVRIHPTSWNNHNWWAMRWEF
FA58C C25F6.4.AA FA58C 23-180 27 2.4e-21 78.18 SMART 1-199 (199) Show / Hide 
Range on Protein: 23-180
Range on HMM: 1-199/199
Sequence Identity: 27% (55 aa)

QCGENALGMQNGDIADSQITASSSFDK------QSVGPQNARLHSELA-----SGAWCPKPQIN------SKSYEFLQVTLND-TFLITSVETQGR----
.|   .||| .| |.|.|||||||.        .  .|  |||. .        .||||.   .       . .....| |   | ..| | |...    
ECN-EPLGMEGGHIPDWQITASSSHYWNRDMPWWYWWPHIARLNGNGSNHDYWDNAWCPWKNDYEDWIFDYHCPHWWLVDLGRKTHRVTGV-TITGRRRR

---YGNGTGREFASH-YMIDY------LRPGSQWIRYK-----NRT-GHVYMDGNFDTTTPVIRVLDPPIVASRIRFVPSSKNTR------TVCMRAEIH
   .|.... ..  . | .|.      .  | .|. ||     . | ..   .||.| ..|.. ...||.||  ||..|  .||.      ..||| |..
GHGWGHDDWWTYYWMMYKDDRRDNNERQ-NGHTWTTYKDFWIEHGTGNSMVFYGNWDNNHPWHNMFHPPMVARYIRIWPTWWNTNATGWHHNYCMRWELY

GC
||
GC
Kinase C25F6.4.AA DDR 520-765 33 1.3e-153 516.62 In-house 1-306 (306) Show / Hide 
Range on Protein: 520-765
Range on HMM: 1-306/306
Sequence Identity: 33% (104 aa)

LLIGKAIGEGKFTMIKECIIFGGLK-----------------CAHKSTKEEDCVHGTRALGDEIACLLQCGRHPRIVELFG---VDESYNLLLEHVEY-G
|.....||||.|.....|...|...                 .|.|......|.|.......||.|..||.|||.||.|.|   .||.|....|..|. |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

CIRNFWMASEAP------------------LDTEFLVRICKDIYSAMAYLESIRIVHGHFTPNNILMDGEFHAKVCSPR----------------G----
....|||..||.                  ...|..|.||..|.|.|.||||...||......|.|...|.|.|.|...                |    
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

PSHHAQLRYSAPESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQPNAVVPLMPTVFNYEIL-QLLTRCFRVDQLERPTFE
..||...|..|.|||....||.|||.||...|..||...||..|||.||.||...|||....||...|...||....|||. ||..||.|.||..||.||
QRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSFE

RLVKPF
...|..
EIHKFL
Kinase C25F6.4.AA TK 520-765 12 1.8e-38 126.02 In-house 1-486 (486) Show / Hide 
Range on Protein: 520-765
Range on HMM: 1-486/486
Sequence Identity: 12% (60 aa)

LLIGKAIGEGKFT---MIKECIIFGGL--------------------------KCAHKSTKEEDCVHGTRALG---------------DEIACLLQC--G
. .|| .||| |    .. ... .|.                           ..| |  ||.|  . .. .                 |.......  |
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPRIVELFG----VD-----------ESYNLLLEHVEYGC----IRNFWMASEAP--------------------------------------------
.|| || |.|    ..           | . ...|....|.     |..  ..  .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDTEFLVRICKDIYSAMAYLESI------RIVHGHFTPNNILMDGEFH-----------AKVCSPR---
                               |... |. .| .| ..|.||.|       ..||.     |.| . . .           .|..      
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------------GPSHHAQ-----------------------------LRYSAPESIVNNE---------FTHKSDAWAVATTVYEMAYQCRQRPYEEL
             .  . ..                             .|. |||..  ..         ||.||| |.   ...|.   ... .|...
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------EQIVDNACALLDHQPN--------AVVPLMPTVFN--------------YEILQLLTRCFRVDQLERPTFERLVKPF
.|         ...... .. . . .            .  |                   |. .|...|.. |  .||||. |.. .
SNQDVWKDGDNQEVMEYLRRGGRL-CRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase C25F6.4.AA TKL 574-765 15 1.1e-19 67.54 In-house 83-364 (364) Show / Hide 
Range on Protein: 574-765
Range on HMM: 83-364/364
Sequence Identity: 15% (46 aa)

RHPRIVELFGVDES----------------YNLLLEHVEYGC-IRNFWMASEAPLDTEFLVRICKDIYSAMAYLESIR--------IVHGHFTPNNILMD
||| || . |.. .                . .  | .. |.   ..          . ..|...|| ..|.|| | .        |.|   ...||| |
RHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVD

GEFH--------------AKVC--------SPRGPSHHA----------------------QLRYSAPESIVNN----------------EFTHKSDAWA
  ..              .|.|        |..| . .                        .|. ||| . ..                |.. |.| ..
ENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYS

VATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQPNAVV----PLMP------------TVFNYEILQLLTRCFRVDQLERPTFERLVKPF
 .   .|..  ||  ||... ..... .   . . .  ...    |..|            . .  .. .|...|   |  .||.|....| .
FGIVLWEILTRCR--PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase C25F6.4.AA TK-Unique 520-765 19 1.1e-18 61.19 In-house 1-294 (294) Show / Hide 
Range on Protein: 520-765
Range on HMM: 1-294/294
Sequence Identity: 19% (60 aa)

LLIGKAIGEGKFTMIKECIIFG-------GLKCAHKSTKEEDCVHGTRALGDEIACLLQCGRHPRIVELFGV---D-ESYNLLLEHVEYG----CIRNFW
| .|. ||||.|  .  . ..|         . |.|  |..   .  ... .||. . . |.|| || ..|.   . |.  ...|....|    ..|.. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

MA---------------------SEAPLDTEFLVRICKDIYSAMAYLES--IRIVHGHFTPNNILMDGEFHAKVC--------------SPRGPSHHAQL
.|                     ...|.. ..|......| ..|.||.|   .|||..    |.|. . . .|.|              |  . ..  ..
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RYSAPESIV--NNEF-THKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQPNAVVPLMPTVF-NYEILQLLTRCFRVDQLERPTFERLVK
|. ||||.    . . | ||| |. . . .|..     .|| .. ...       .... .. . .. |    . |. .|. .|.. .  |||.|. ...
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGA-CPYPGMPWKD-------IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKH

PF
 .
RL
Kinase C25F6.4.AA TyrKc 520-765 21 3.1e-15 23.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 520-765
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

LLIGKAIGEGKFTMIKECIIFGGLKCAHKSTKEEDCVHGTRALGDEIACLLQCG-RHPRIVELFGV---D-------ESYNLLLEHVEYGCIRNFWMASE
.  || .||| |  . ...    ...| |. ||.      ... .|.  . . | .|| || |.||   .       | . ...|....|. ...  ...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

APLDTEFLVRICKDIYSAMAYLESIRIVHGHFTPNNILMDGEFHAKVC----SPRGPSH----------------HAQ----LRYSAPESIVNNEFTHKS
  | .. |. .| .| . |.||.| ...|      |.| . ....|..    |  . ..                ..     .|  |||.|  ..||.||
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DAWAVATTVYEMAYQCRQRPYEE-----LTNEQIVDN--ACALLDHQPNAVVPLMPTV----FNYEILQLLTRCFRVDQLERPTFERLVKPF
| |.   . .|.   . | ||..     ..|.... .  .   ..  ||.     | .       |. |. ..| . |  .||||. ... |
DVWSFGVCMWEIFTYGQQ-PYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase C25F6.4.AA Pkinase_Tyr 520-637 25 6.4e-14 47.77 Pfam 1-134 (270) Show / Hide 
Range on Protein: 520-637
Range on HMM: 1-134/270
Sequence Identity: 25% (34 aa)

LLIGKAIGEGKFTMIKECIIF-----GGLKCAHKSTKEEDCVHG---TRALGDEIACLLQCGRHPRIVELFGVDE----S--YNLLLEHVEYGCIRNFWM
. .|| .||| | ...... .     .....| |. || .. |     ...  |.. . | |.|| || | ||      .  . . .|....|. ...  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AS---EAPLDTEFLVRICKDIYSAMAYLESIRIVH
.    . ||... |. .| .| ..|.||||....|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH
Kinase C25F6.4.AA S_TKc 520-766 19 4.9e-13 14.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 520-766
Range on HMM: 1-231/231
Sequence Identity: 19% (54 aa)

LLIGKAIGEGKFTMIKECIIFG-GLKCAHKSTKEEDCVHGTRALGDEIACLLQCGRHPRIVELFGVDE--SYNLLLEHVEY--GCIRNFWMASEAP----
  |.. ||.| |   . |.  . | ..| |  |        . .  ||..| .  .|| || |..| .  .. . .|...   |  . .      .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDTEFLVRICKDIYSAMAYLESIRIVHGHFTPNNILMDGEFHAKVC---------SPRGPSHHAQLRYSAPESIVNNEFTH-KSDAWAVATTVYEMAYQ
 ..     .... | .|..|. | .|.|    | |||.|   | |.|         .  |  .     | ||| .    ... |.| |..  ..|||.. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPW-----YMAPEVL---GYGKCKCDWWSCGCILYEMLC-

CRQRPYEELTNEQIVDNACALLDHQPNAVVPLMPTVFNYEILQLLTRCFRVDQLERPTFERLVK--------PFQ
 .. |..  . ... .. .                    | .... .|...|  .|||   . .        |. 
-GYPPFP--QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C25F6.4.AA UTK 671-765 27 4.3e-11 34.18 In-house 207-296 (296) Show / Hide 
Range on Protein: 671-765
Range on HMM: 207-296/296
Sequence Identity: 27% (27 aa)

APESIVNN-EFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACAL--LDHQPNAVVPLMPTVFNYEILQLLTRCFRVDQLERPTFERLVKPF
|||.....  ||.||| |.   ...|.     ..||....|.|.. . |.   . . ... .|.       .. .|..|| . |  |||.||.||. .
APEALTHHTRFTTKSDVWSFGVVCWEIWTW-GRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPH-------PVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase C25F6.4.AA RTKB 564-695 26 5.3e-10 29.94 In-house 50-202 (264) Show / Hide 
Range on Protein: 564-695
Range on HMM: 50-202/264
Sequence Identity: 26% (41 aa)

DEIACLLQCGRHPRIVELFG---VDESYNLLLEHVEYGCIRNFWMASEAP------LDTEFLVRICKDIYSAMAYLESIRIVHGHFTPNNILMDGEFHAK
.|.. .   | || .. ..|    || | || |  |.|  | .  .. |.      |  . ||  | .| . ||.|..  ..|.     |.| | ..| |
SEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRASQHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCK

VCSP-----------RGPSHHAQLRYSAPESIVNNEFTHKS-DAWAVATTVYE
.|             . . .    .  ||||.    .| || | |.   | .|
ICDFGMAREIDHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTMWE
Kinase C25F6.4.AA EGFR 673-766 27 2.6e-08 23.52 In-house 173-258 (258) Show / Hide 
Range on Protein: 673-766
Range on HMM: 173-258/258
Sequence Identity: 27% (26 aa)

ESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQPNAVVPLMPTVFNYEILQLLTRCFRVDQLERPTFERLVKPFQ
|.| .  .||.|| |.   |. |.     |.||. .  ..| |    ||..      |   |.    . ... .|  .|.  ||||. |.. |.
ECIHHRCYTHQSDVWSYGVTCWELMTFG-QKPYDGIPAREIPD----LLEKGERLPQPPICTI---DVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase C25F6.4.AA TKL-Unique 659-765 21 2.7e-07 21.97 In-house 182-290 (290) Show / Hide 
Range on Protein: 659-765
Range on HMM: 182-290/290
Sequence Identity: 21% (24 aa)

RGPSHHAQLRYSAPESIVN--NEFTHKSDAWAVATTVYEMAYQCR----QRPYEELTNEQIVDNACALLDHQPNAVVPLMPTVFNYEILQLLTRCFRVDQ
|...  . .|..||| . .  . .. ||| .. .. ..|.|  ..     .||.... ||.    |....       |  |.  ..|.  |...|.. | 
RNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQW----CEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDP

LERPTFERLVKPF
 .||.|.  ..  
SQRPSFDEIIHRL
Kinase C25F6.4.AA Pkinase_Tyr 671-715 32 3.4e-07 24.97 Pfam 182-226 (270) Show / Hide 
Range on Protein: 671-715
Range on HMM: 182-226/270
Sequence Identity: 32% (15 aa)

APESIVNNEFTHKSDAWAVATTVYEMAYQCRQRP-YEELTNEQIVD
|||.| ...||.||| |.   . .|.   ..  | |....||....
APECINYGKFTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYE
Kinase C25F6.4.AA Frk 667-761 31 8.9e-07 19.14 In-house 166-252 (260) Show / Hide 
Range on Protein: 667-761
Range on HMM: 166-252/260
Sequence Identity: 31% (30 aa)

LRYSAPESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQPNAVVPLMPTVFNYEILQLLTRCFRVDQLERPTFERL
... ||| .  |.|| ||| |.    ..|.    |  ||  .|| ....     .||      |    .  |||..    |...|  .||||| |
IKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRM-PYPGMTNAEVLQ----MVDHGYRMPQPPNCPQQLYEIML---ECWHSDPMKRPTFETL
Kinase C25F6.4.AA RTKE 667-765 22 8.9e-07 19.09 In-house 191-293 (293) Show / Hide 
Range on Protein: 667-765
Range on HMM: 191-293/293
Sequence Identity: 22% (24 aa)

LRYSAPESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQP--------NAVVPLMPTVFNYEILQLLTRCFRVDQLERPTF
.|. |||..  . |. ||| ||    ..|. . . | || ..  .|..    .....|.        ...|.. |.. .  . .| . | ...  .||.|
RRWWAPEVWKDQHFSFKSDVWAYGCLCWEV-WNNGQMPYAHMDDQQFMQ---RIVQCQMPSGGHLGDHEPVHAPPVHCPPWADRLMQWCLCINPEHRPNF

ERLVKPF
  |.   
AQLYQMW
Kinase C25F6.4.AA Pkinase 667-765 18 5.3e-05 18.76 Pfam 175-293 (293) Show / Hide 
Range on Protein: 667-765
Range on HMM: 175-293/293
Sequence Identity: 18% (22 aa)

LRYSAPESIV-NNEFTHKSDAWAVATTVYEMAYQCRQRPYEEL------TNEQIVDNACALLDHQPNAVVPLMP-------------TVFNYEILQLLTR
..| ||| |  ... ..|.| |..  ..|||.   .. |. .       .  |....      | .      ..             .  . | ......
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC--GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CFRVDQLERPTFERLVKP--F
|...|  .|||.| ...   |
CLCKDPKKRPTAEQILQHPWF
Kinase C25F6.4.AA TKL-Unique 617-656 27 0.001868 8.26 In-house 113-159 (290) Show / Hide 
Range on Protein: 617-656
Range on HMM: 113-159/290
Sequence Identity: 27% (13 aa)

VRICKDIYSAMAYLESIR--IVHGHFTPNNILMDGE-----FHAKVC
|.. .|| ..| ||..    | |.  .. |.| | .     . .|.|
VKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKIC
Kinase C25F6.4.AA RTKB 732-765 23 0.002711 6.98 In-house 231-264 (264) Show / Hide 
Range on Protein: 732-765
Range on HMM: 231-264/264
Sequence Identity: 23% (8 aa)

MPTVFNYEILQLLTRCFRVDQLERPTFERLVKPF
.|   . ..  ....|  ..  .||.|. ||. |
KPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase C25F6.4.AA RTKE 604-638 24 0.00312 6.81 In-house 102-138 (293) Show / Hide 
Range on Protein: 604-638
Range on HMM: 102-138/293
Sequence Identity: 24% (9 aa)

WMASE--APLDTEFLVRICKDIYSAMAYLESIRIVHG
| ..   .|...| . ..   . ..|..||.  |||.
WLQDHHGRPTSHEDQIHCLHQVACGMSFLERLGIVHR
Kinase C25F6.4.AA UTK 605-638 29 0.003366 6.8 In-house 109-142 (296) Show / Hide 
Range on Protein: 605-638
Range on HMM: 109-142/296
Sequence Identity: 29% (10 aa)

MASEAPLDTEFLVRICKDIYSAMAYLESIRIVHG
.| .. |. . ..  . || ..|.||.| ..||.
PACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHR
Kinase C25F6.4.AA Frk 574-655 22 0.003899 6.31 In-house 52-139 (260) Show / Hide 
Range on Protein: 574-655
Range on HMM: 52-139/260
Sequence Identity: 22% (20 aa)

RHPRIVELFGV---DESYNLLLEHVEYGCIRNFWM---ASEAPLDTEFLVRICKDIYSAMAYLESIRIVHGHFTPNNILMDGEFHAKV
|||....|. |   .|   .. | .. | . ..          .  . || .   . . ||||||   .|      |.|.. .   |.
RHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKI
Kinase C25F6.4.AA Pkinase 565-637 20 0.00709 11.25 Pfam 50-131 (293) Show / Hide 
Range on Protein: 565-637
Range on HMM: 50-131/293
Sequence Identity: 20% (17 aa)

EIACLLQCGRHPRIVELFGVDE---SYNLLLEHVEYG--CIRNF-WMA--SEAPL--DTEFLVRICKDIYSAMAYLESIRIVH
||. .. . .|| ||.|... |   .. . .|..| |  ..  | ..   .. ..  . . . .... | ....|. | .|.|
EIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase C25F6.4.AA EGFR 574-637 30 0.036281 2.79 In-house 59-124 (258) Show / Hide 
Range on Protein: 574-637
Range on HMM: 59-124/258
Sequence Identity: 30% (20 aa)

RHPRIVELFGV--DESYNLLLEHVEYGCIRNFWMASEAPLDTEFLVRICKDIYSAMAYLESIRIVH
.|| .| | ||   ..  |      |||. ..       .    |.  |  | . | |||  |.||
DHPHLVRLLGVCMHSQMQLVTQYMPYGCLLDYVRQHKDNIGSQHLLNWCVQIAKGMQYLEEHRMVH
Kinase C25F6.4.AA Pkinase_Tyr 742-765 29 1.030204 3.04 Pfam 247-270 (270) Show / Hide 
Range on Protein: 742-765
Range on HMM: 247-270/270
Sequence Identity: 29% (7 aa)

QLLTRCFRVDQLERPTFERLVKPF
.|...| . |  .||||. ..  .
DLMKQCWHYDPEDRPTFSEIHEQL