Gene C03C10.1 (Nematode worm)
C03C10.1
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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C03C10.1.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 283 | Kinase domain by global Sugen HMM | Fasta, JSON |
C03C10.1.AA | Protein | Genbank | 341 | None | Fasta, JSON |
Protein domains of C03C10.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | C03C10.1.AA | CK1 | 16-274 | 73 | 8.9e-213 | 713.16 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 16-274 Range on HMM: 1-271/271 Sequence Identity: 73% (198 aa) YKLIRKIGSGSFGDIYVSINVTNGEE--VAIKLESNRARHPQLLYESKVYRILQG------GVGIPHIRWYGTE--REYNVLVMDLLGPSLEDLFNFCSR |...||||.||||||| ||.||||| ||||||.|...||||.||.|.|.|||| ..||||..|.|.| ..||..||||||||||||||||.| YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR RFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGI-GRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDME .|..|||||.||||| |||||| ||||||||||||||||. |.||.....|||||||.|||..|..||||||.|||||||||||||.||||||||||||| KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME SLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKG-FPAEFPMYLSYTRGLRFDESPDYM |||||||||.||.||||||||.|||||||||.||||.|.||.|||| ||.|| ||| |.|.|.|.| |||| SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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Kinase | C03C10.1.AA | CK1-A | 16-276 | 86 | 1.8e-208 | 698.87 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 16-276 Range on HMM: 1-261/261 Sequence Identity: 86% (226 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLML |.|.||||||||||||..||.|||||||||.|||.||||||.||.||||||||.|||||.||||.|..|||.||||||||||||||||.||||||||||| YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML ADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNR |||||.||||||.|||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||.|||.||||| ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR GTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYL |.|||||.||.||||||||||||||.|..|.|||||||||.||..|.|.|||.|.|||||| GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | C03C10.1.AA | CK1-Unclassified | 16-248 | 65 | 7.1e-199 | 592.54 | In-house | 1-244 (244) | Show / Hide |
Range on Protein: 16-248 Range on HMM: 1-244/244 Sequence Identity: 65% (159 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGV-------GIPHIRWYGTE--REYNVLVMDLLGPSLEDLFNFCSRR |..|.|||.||||.|| ||. ..||||||||.. ..||||.|| |....||.| |||.. |.|.| ..||..||||||||||||||.| |. YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK FTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDS-RTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDME |..|||||.||||| ||||.| |||||||||||||||| |.. .....|||||.|.|.|. .| .||||||.|||||||||||||||||||||||||.| FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE SLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLC ||||||.|| .|.||||..|| .||.||||| |.||.|.||.|| SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC |
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Kinase | C03C10.1.AA | CK1-D | 16-276 | 71 | 1.6e-182 | 612.64 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 16-276 Range on HMM: 1-261/261 Sequence Identity: 71% (187 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLML |.. |||||||||||| |....||||||||. ...|||| .|||.|...|||.|||.|||.| | .|||.||||||||||||||.|.|.| .|||||| YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML ADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNR ||||| ||||.| .|||||||||||||||.|.. | ..|||||||.|||.||. ||||||.||||||||||||| |.|||||||||.|||||||||||| ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR GTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYL |.|||||||||||.||||.|.|||| |... ||||.| || |. |.| |.||. |||.|| GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | C03C10.1.AA | CK1-G | 16-276 | 54 | 8.60000000001e-143 | 480.68 | In-house | 1-266 (266) | Show / Hide |
Range on Protein: 16-276 Range on HMM: 1-266/266 Sequence Identity: 54% (146 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGV-GIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLM |. .||| |.|| .. |. |.| ||||.| . | ||| | . |.|| | . |||.. ..| . ||..|||||||||||||..| |.|..|||.| YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM LADQMIGRIEYVHVKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMY .| ||| |.|||| .. | ||.|||||| | .. .....||||.||.|.| .|. |||||| | ||||||| ||| ||| |||||||||.|| . || VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY FNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKG--FPAEFPMYLSYTRGLRFDESPDYMYL | || |||||||| . |..|.|| ..| | .| ||.. || .| || | | | |.| ||| || FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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Kinase | C03C10.1.AA | CK1 | 16-276 | 39 | 1.6e-141 | 476.43 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 16-276 Range on HMM: 1-339/339 Sequence Identity: 39% (134 aa) YKLIRKIGSGSFG-DIYVS-----INVTNG-----EEVAIKLESNRAR--HPQLLYESKVYRILQGG-------------------VGIPHIRWYGTERE .|...|||.|.|| .|| ....|. ||.|.|.|.. .. ||||..|...|..|||| ...|...||..|.. WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED --YNVLVMDLLGPSLEDLFN---FCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGI------GRHCN--------KLFLIDFGLAK-KY ||..||.||||.||||.. .| |.|.|||.||.|.||. ..||.| ..|||||||||||.||. |.| . ....||||.|. || DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY RDS-----------RTRTHIPYRE---DKNLTG-TARYASINAHLGIEQSRRDDMESLGYVLMYFNRGT--LPWQGLKAATK-------KQKYEKISEKK ||. .| |.|.|| |...| ||||.|||.|||.||.||||..|..|.|.....|| ||||..|. .| |.|||.|.||| RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK MTTSVEHLCKG-----FPAEFPMYLSYTRGLRFDESPDYMYL | |... ||.. .| || ... | |.|.... |||... MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | C03C10.1.AA | Worm6 | 16-276 | 27 | 1.6e-58 | 200.71 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 16-276 Range on HMM: 1-279/279 Sequence Identity: 27% (79 aa) YKLIRKIGSGSFGDIYVSINVTNGE--EVAIKLES--NRARHPQLLYESKVYRIL--QGGVGIPHIRWYGTERE--YNVLVMDLLGPSLEDLFNFC-SRR .|. .|||.|.||..|.. . .... ..|.|.|. . ...| | | . ... . . | .|. .. .| .|| |.|..|.|| .. |. WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK FTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGI-----GRHCNKLFLIDFGLAK--KYRDSRT-----R-THIPYREDKNLTGTARYASINAHL |.| | | .| |.. .|| .| |||||.|| || | . .....|||... ||.. . | |....| || |||....| FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFR------GTVRYAPLACHK GIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQ-KYEKISEKKMTTSVEHLCKGFPA-EFPMYLSYTRGLRFDESPDYMYL |.||.|.||.|| |.. . .|.|||...|. .. .... .. . . . ...|. ||. . | .... . ||| .. GQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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Kinase | C03C10.1.AA | TTBKL | 16-280 | 29 | 2e-56 | 188.99 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 16-280 Range on HMM: 1-288/288 Sequence Identity: 29% (86 aa) YKLIRKIGSGSFGDIY-VSINVTNGEEVAIKLESNR-ARHPQLL-YESKVYRILQ--GGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLF--NFCSRRFT .. ...||.| || .| |. .. ... | | |.|| .. .. . | .| || | .|.. ..| . || .|| |.||.| || . . .||. WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS MKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRH----CNKLFLIDFGLAKKYRDSRTRT----------HIPYRE---DKNLTGTARYASINA |.. .. | . . ..| . |||||.|| |. .|. | | ..|||||.|..|... . . . |. . || ||.|.|. DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM HLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKG------FPAEFPMYLSYTRGLRFDESPDYMYLRQLF |.. ||.| ||. |. |...... | |||.... . ..| ..|. .. | |.|. .| || . . | ||. . |||......| HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | C03C10.1.AA | TTBK | 16-276 | 37 | 2.5e-52 | 180.16 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 16-276 Range on HMM: 1-257/257 Sequence Identity: 37% (101 aa) YKLIRKIGSGSFGDIYVSINVTNG-EEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHI-RWYGTER--EYNVLVMDLLGPSLEDLFNFCSR-RFTMK | ..||| | || || .. | |.||||.|| .. | | | . || | .|. | .| | ..| .||.|.| .| || .| |.. WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQ---GCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLS TVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYV | | | |.. || .| | |||||| || || |.| ...||||| .| . | || ||.||||||||. | |.||. || |. TTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYM LMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYL | | | ||| .| ... | | | | | || ... . | . . ||| . LVEFVQGQLPWRKIKDK------DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | C03C10.1.AA | Pkinase | 16-235 | 23 | 3e-37 | 132.78 | Pfam | 1-230 (293) | Show / Hide |
Range on Protein: 16-235 Range on HMM: 1-230/293 Sequence Identity: 23% (56 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLY------ESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFC------ |...||||||||| | ... .|..||.| . | .... .. | .. . |. . ..|. ..... .||.... |. .. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLY-VMDLFDYISTW -SRRF--TMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHL-GIEQS ...| ..... . . |.. .|| | ...||||.||.|.|. | . .. ..||||||... . ... . ..|| .|.. .. | . . RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG RRDDMESLGYVLMYFNRGTLPWQGL----KAATKKQKYEKI .. || |.| .| .. | .|..| . ....|....| PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRI |
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Kinase | C03C10.1.AA | VRK | 87-229 | 36 | 1e-27 | 86.21 | In-house | 106-251 (284) | Show / Hide |
Range on Protein: 87-229 Range on HMM: 106-251/284 Sequence Identity: 36% (54 aa) LVMDLLGPSLEDLFN-FCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLT--GT .||. .| .|. . . ||.||||| || .|. || | .. | ||| | | | .. .|.|.||| .| .. | .| ||. || MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPN--GKHRQYKEDPRRCHNGT ARYASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKA--ATKK . |. ||.| ||| | |.||| .|. |.||| .. ..| CEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCLQQQDPEK |
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Kinase | C03C10.1.AA | S_TKc | 16-292 | 18 | 7.6e-14 | 26.14 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 16-292 Range on HMM: 1-231/231 Sequence Identity: 18% (55 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRR--------F |...||||.|.|| | ... |..|||| . ... | .. . . | .. . . .. .||.... .| ||| . .| | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF TMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSR-RDDMESL . .. .. |.. .|| | ...||||.||.| |. . ..|||||... . . || | . .. . |. |. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC GYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYLRQLFRI-------LFRTLN-------HQYD | .| . | |.. . .. ..|| .. .|.... |. |.. GCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | C03C10.1.AA | TyrKc | 16-274 | 18 | 6.5e-05 | -143.16 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 16-274 Range on HMM: 1-280/280 Sequence Identity: 18% (57 aa) YKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRIL-QGGVGIPHIRWYGTER-------EYNVLVMDLLGP-SLEDLFNFCSRR .|..|.|.| || .| . ..||.| . | . .. | .. . | | . . |. | .|| . .| | . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK FTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLI---DFGLAKKYRDS---RTRTHIPYREDK--NLT--GTARYASINAHLGIE ..||. | . | || | ||.||||. | | | .. . ||||... | . || . . | .. LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAP------- QSRRDDMESL-GY------------VLMY--FNRGTLPWQGLKA--ATKKQKYEKISEKKMTTSVEHLCKGFP-----AEFPMY--------LSYTRGLR |.. . |.|. | .| |. | . .. .|.. . .. .. . | . || . -------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPEDRPT FDESPDYM | | ... FSEIHECF |
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Kinase | C03C10.1.AA | VRK | 16-31 | 50 | 0.020451 | 4.05 | In-house | 1-16 (284) | Show / Hide |
Range on Protein: 16-31 Range on HMM: 1-16/284 Sequence Identity: 50% (8 aa) YKLIRKIGSGSFGDIY ..| ..||.| || || WRLGKPIGQGGFGCIY |