Gene B0198.3 (Nematode worm)

B0198.3

Species: Nematode worm
Alias: CE02931, aSWK263, B0198.3, B0198.3x=(isvg..kdrk)
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 12053057-12046688, WormBase Genetic Map location: X:6.78,

Classification

Group: Other
Family: Worm1

Sequence

Name Sequence Type Origin Length Description Download
B0198.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 301 Kinase domain by global Sugen HMM Fasta, JSON
B0198.3.AA Protein Genbank 1030 None Fasta, JSON

Protein domain

Protein domains of B0198.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase B0198.3.AA Worm1 705-1005 80 2.7e-284 950.76 In-house 1-301 (301) Show / Hide 
Range on Protein: 705-1005
Range on HMM: 1-301/301
Sequence Identity: 80% (243 aa)

TTVVDSARSHCYSLKISKDYSEQTMAAMRKELEFLQSLPAHQNCVRFDGVLIGKWESNPYQVVGILMENCRGGSLHNYIISVGSVLRRQVMVTPVTADSG
|||||..|.|||||||.|||..|||.||||||||||.||.||||.|||||.||.|..|||||.||||||||||.|||||||||||.|||||.||||....
TTVVDVVRRHCYSLKIPKDYTPQTMSAMRKELEFLQTLPPHQNCRRFDGVVIGRWDDNPYQVIGILMENCRGGTLHNYIISVGSVFRRQVMCTPVTDHDS

RQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHFGRVSIRFSQFAEQISSALEHLHCAGIVHTRVTTISVYLLREYTDPLDMLCDQMV
.|||||||||||.|....||||||.||.||.|||.||||.|..|||.||||||.||||||||||||||||||||||||||..|||..||||.||||||||
FQSQHDDHPLRIMNSTQHPSSGYDKFSTKDDKAPNCHQDVDIQQHFDRVSIRFCQFAEQISSALEHLHCAGIVHTRVTTINIYLLHNYTDPFDMLCDQMV

KLGDFGNSARSADDVIIDQNLQPPEVALGKKYEAKGDIWQFGTCLAEMCSLGVPYQAQKQIPASGLDEFDKLPSTCVLQDAAKKCLNARNRPSASDLRGV
|||.||.|....||||||||||||||..||||||.|||||||||||||||||.|||.|||||.||.||||.||||||||||||.|||||||||||||.||
KLGNFGFSVQNSDDVIIDQNLQPPEVIKGKKYEARGDIWQFGTCLAEMCSLGDPYQSQKQIPKSGHDEFDNLPSTCVLQDAAKRCLNARNRPSASDLCGV

F
|
F
Kinase B0198.3.AA TyrKc 716-1005 13 2.4e-09 -71.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 716-1005
Range on HMM: 1-280/280
Sequence Identity: 13% (50 aa)

YSL-----------------------KISKDYSEQTMAAMRKELEFLQSL-PAHQNCVRFDGVLIGK----WESNPYQVVGILMENCRGGSLHNYIISVG
 .|                       |  |...   ......|.. . .| . |.| ||. || . .     .. |. .|   || . .|.|..|. . .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV---MEYMPHGDLKDYLRKHR

SVLRRQVMVTPVTADSGRQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHFGRVSIR-FSQFAEQISSALEHLHCAGIVH--------
                                                                 .. . . .|. ||..  |.||  ...|        
PK---------------------------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNC

---TRVTTISVYLLREYTDPLDMLCDQMVKLGDFGNSARSADD-------VIIDQ----NLQ--------PPEVALGKKYEAKGDIWQFGTCLAEMCSLG
    .                       || .||| |    ||         ...    .          .||.   .|.  | |.| || |. |....|
LVGENH---------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYG

VPYQAQ------------KQIPASGLDEFDKLP-------STCVLQDAAKKCLNA--RNRPSASDLRGVF
 .                ... . .  .  . .        .  . .  |.| ..   .||. |...  |
QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase B0198.3.AA TK-Unique 718-956 16 1.4e-08 25.78 In-house 35-236 (294) Show / Hide 
Range on Protein: 718-956
Range on HMM: 35-236/294
Sequence Identity: 16% (46 aa)

LKISKDYSEQT-MAAMRKELEFLQSLPAHQNCVRFDGVLIGKWESNPYQVVGILMENCRGGSLHNYIISVGSV----------------LRRQVMVTPVT
.|  ||.. .|  ... ||......|..|.| |.. |. . .   ...    |.|| |..|.| .|. . . .                 ..... .|..
VKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWM----IIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPIS

----ADSGRQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHFGRVSIRFSQFAEQISSALEHLHC--AGIVHTRVTTISVYLLREYTD
    .                                                          || || ...|.|.    .||| .. .  | | .    
PKDLYH---------------------------------------------------------FAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----

PLDMLCDQMVKLGDFGNSARSADDVIIDQNLQ---------PPEVAL--GKKY-EAKGDIWQFGTCLAEMCSLG
      | ..|..||| . .  ..  .. . .         .||. .  .. |   |.|.| ||  . |...||
------DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLG
Kinase B0198.3.AA S_TKc 706-1005 17 3.6e-07 -71.71 SMART 17-231 (231) Show / Hide 
Range on Protein: 706-1005
Range on HMM: 17-231/231
Sequence Identity: 17% (56 aa)

TVVDSARSHCYSLKISKDYSEQTMAAMRKELEFLQSLPAHQNCVRFDGVLIGKWESNPYQVVGILMENCRG--GSLHNYIISVGSVLRRQVMVTPVTADS
 ...    . . .|| |         .|.|.. |..   | | |.. .|          . . . || | |  |.|. || . |.  .|...   ...  
KCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR--

GRQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHFGRVSIRFSQFAEQISSALEHLHCAGIVHTRVTTISVYLLREYTDPLDMLCDQM
                                                        .. || .|||..|  ||.|  .    . | .             
-------------------------------------------------------FYMYQICCALEYCHSHGIIHRDLKPENILLDE------------H

VKLGDFGNSARSADDVIIDQNLQPPEVALGKKYEA-KGDIWQFGTCLAEMCSLGVPYQAQKQIPASGLDEFDKLPSTCVLQDAAKKCLN--ARNRPSASD
.|..||| ...  . ..   .  .|||    .|   | |.| .| .|.||..   |..            |.|.  .  . |  .|||.   ..||.| .
IKICDFGLARQL-TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-E

LRG---------VF
.            |
ALQDEWDIKCHPWF
Kinase B0198.3.AA NAK 731-783 31 1.1e-05 14.85 In-house 52-105 (299) Show / Hide 
Range on Protein: 731-783
Range on HMM: 52-105/299
Sequence Identity: 31% (17 aa)

AMRKELEFLQSLPAHQNCVRFDG-VLIGKWESNPYQVVGILMENCRGGSLHNYI
|...|.|... |. | | |....  . .. .||  . | .||| |..||| ...
ACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGSLWDLM
Kinase B0198.3.AA TKL 768-878 12 1.2e-05 16.37 In-house 114-163 (364) Show / Hide 
Range on Protein: 768-878
Range on HMM: 114-163/364
Sequence Identity: 12% (15 aa)

GILMENCRGGSLHNYIISVGSVLRRQVMVTPVTADSGRQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHFGRVSIRFSQFAEQISSA
.| || | ||||..|..                                                                       .. ..| .|...
CIVMEYCPGGSLLHYLH---------------------------------------------------------------------WHQRCRWALDIARG

LEHLHCAG--------IVH
...||  .        |.|
MNYLHSMNPKWCTKPPIIH
Kinase B0198.3.AA NEK2 928-964 48 1.9e-05 14.14 In-house 233-269 (319) Show / Hide 
Range on Protein: 928-964
Range on HMM: 233-269/319
Sequence Identity: 48% (18 aa)

PEVALGKKYEAKGDIWQFGTCLAEMCSLGVPYQAQKQ
||.  | ||  | |||  |  . |||.|  | ||  |
PEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQ
Kinase B0198.3.AA STE-Unique 928-990 24 2.7e-05 14.11 In-house 517-586 (616) Show / Hide 
Range on Protein: 928-990
Range on HMM: 517-586/616
Sequence Identity: 24% (17 aa)

PEVALGK-----KYEAKGDIWQFGTCLAEMCSLGVPYQAQKQIPA--SGLDEFDKLPSTCVLQDAAKKCL
||| ...      | .| ||| .|  . .||.. .|.  .  . |  . ..   ..|  | ... ..||.
PEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIHCQPPQCPIENIPPKCQ
Kinase B0198.3.AA TKL 927-1005 16 3.9e-05 14.45 In-house 241-364 (364) Show / Hide 
Range on Protein: 927-1005
Range on HMM: 241-364/364
Sequence Identity: 16% (20 aa)

PPEVALGK----------------KYEAKGDIWQFGTCLAEMCSLGVPYQAQKQIPAS---------GLDEFDKLP----------------STC--VLQ
.|||  |.                .|  | |.. || .| |...  .||. .. .|            ..  ..|.                ..|   . 
APEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMK

DAAKKCLNA--RNRPSASDLRGVF
. ...| ..  ..|||....   .
KLMQDCWDHDPEKRPSFQEILKRL
Kinase B0198.3.AA HH498 928-968 33 5e-05 11.44 In-house 194-235 (284) Show / Hide 
Range on Protein: 928-968
Range on HMM: 194-235/284
Sequence Identity: 33% (14 aa)

PEVAL-GKKYEAKGDIWQFGTCLAEMCSLGVPYQAQKQIPAS
|||   . ||  | |.  .. |. || .  ||.   |.. |.
PEVFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAA
Kinase B0198.3.AA TK 898-1005 12 7.6e-05 11.33 In-house 272-486 (486) Show / Hide 
Range on Protein: 898-1005
Range on HMM: 272-486/486
Sequence Identity: 12% (28 aa)

MLCDQM------------VKLGDFG----------NSARSADDVIIDQ----NL--------------------------QPPEVALGKK---------Y
......            .|..|||              | ||   ..    ..                           .||. ....         .
LVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKF

EAKGDIWQFGTCLAEMCSLG-VPYQA----------------QKQIPA------SGLDE-----FDKL--PSTC---------------VLQDAAKKCLN
  | |.| || .. |....| .||                   ... .      ||| .     . .   |  .               ...|  ..| .
TTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGL-NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWH

A--RNRPSASDLRGVF
.  . ||. |.|.  .
YDPEDRPTFSQLHEQL
Kinase B0198.3.AA Ciliate-E2 769-878 12 0.00014 11.62 In-house 111-184 (365) Show / Hide 
Range on Protein: 769-878
Range on HMM: 111-184/365
Sequence Identity: 12% (17 aa)

ILMENCRGGSLHNYIISV----GSVLRRQVMVTPVTADSGRQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHFGRVSIRFSQ-FAEQ
. || | ||.|  ||..     .. .                                                            .. ...  . . .|
LVMEYCQGGDLFDYIKNNKKKRNHEIE-------------------------------------------------------K-D-KYFTEKEIKYIMKQ

ISS---------------ALEHLHCAG-IVH
| .               |||.||  . |.|
ILQGFKTKAEFYIACIILALEYLHSKNNIIH
Kinase B0198.3.AA NEK8 928-955 50 0.000186 8.5 In-house 191-218 (278) Show / Hide 
Range on Protein: 928-955
Range on HMM: 191-218/278
Sequence Identity: 50% (14 aa)

PEVALGKKYEAKGDIWQFGTCLAEMCSL
||   ||.| .| |.|  |  | |||.|
PEMCEGKPYNQKSDMWALGCVLYEMCCL
Kinase B0198.3.AA Pkinase 718-878 16 0.000226 16.54 Pfam 32-131 (293) Show / Hide 
Range on Protein: 718-878
Range on HMM: 32-131/293
Sequence Identity: 16% (28 aa)

LKISKDYSEQTMAAMR-KELEFLQSLPAHQNCVRFDGVLIGKWESNPYQVVGILMENCRGG----SLHNYIISVGSVLRRQVMVTPVTADSGRQSQHDDH
.| ... |.. ... |  |.. ...|  | | ||. ..     ....|    . || |.||    .|. ||                             
IKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIY----MVMEYCEGGLYVMDLFDYIST---------------------------

PLRINNASPNPSSGYDSFSSKDRKAPDCHQDTDPAQHF--GRVSIRFSQFAEQISSALEHLHCAGIVH
                                .    |      ..|  .. || ..||..|  ||.|
--------------------------------WRHGCFYFSEWECKF--YMYQILRGLEYCHSMGIIH
Kinase B0198.3.AA Ciliate-E2 904-965 26 0.000581 9.47 In-house 195-300 (365) Show / Hide 
Range on Protein: 904-965
Range on HMM: 195-300/365
Sequence Identity: 26% (29 aa)

VKLGDFGNSARSADD---------------------------VIIDQNL----------QPPEVALGKK---------YEAKGDIWQFGTCLAEMCSLGV
.|. |||.| .  ||                            || ||.          ..||.  |||         |  | ||| .| .| ||..   
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYQAQKQI
|.  |.||
PF--QQQI
Kinase B0198.3.AA NEK8 862-878 41 0.000916 6.49 In-house 126-142 (278) Show / Hide 
Range on Protein: 862-878
Range on HMM: 126-142/278
Sequence Identity: 41% (7 aa)

EQISSALEHLHCAGIVH
.|..||. |.| ..|.|
FQMCSAVHHMHQHNILH
Kinase B0198.3.AA TK 769-878 6 0.052554 1.65 In-house 132-263 (486) Show / Hide 
Range on Protein: 769-878
Range on HMM: 132-263/486
Sequence Identity: 6% (13 aa)

ILMENCRGGS----LHNYIISVGSV---------------------LRRQVMVTPVTADSGRQSQHDDHPLRINNASPNPSSGYDSFSSKDRKAPDCHQD
|.|| . .|.    |..|  .                         ..                                                    
IVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHC----------------------------------------------------

TDPAQHFGRVSIRFSQ---------------------------------------------------------FAEQISSALEHLHCA------GIVH
             .                                                           .. ||....|.||        ..||
-------------M-KGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVH