Gene aSWK213 (Nematode worm)

aSWK213

Species: Nematode worm
Alias: Y18H1A_68.g, Y18H1A.10, aSWK213
External Links:
Annotation:

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
aSWK213.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 247 Kinase domain by global Sugen HMM Fasta, JSON
aSWK213.AA Protein Sugen 440 None Fasta, JSON

Protein domain

Protein domains of aSWK213.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase aSWK213.AA Haspin 107-372 36 3.7e-124 418.76 In-house 1-264 (264) Show / Hide 
Range on Protein: 107-372
Range on HMM: 1-264/264
Sequence Identity: 36% (100 aa)

KVKKLGEGAYGEVFSTVWNGRPVAIKVLPFENNGC-FYGN-QSVEIPTTHAVLSEVIVMKELSALRDPNSWNSTPNFIEMISAQIVMGEYPKGLLRAWDA
..||.|||.||||||..|||..|..|..|.... | .||. ......|....|.|.|.||....|.. | ....|||..|.....|.|...|.|. .|| 
NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH

YDKLNESEHLRPDVYSSEHQNFILFVSANGGISLADF--VLESEDELFSIIHQLVLSMVAAEAALEFEHRDLNLSNVLID-RNGVEELSYTVHGQKIPLR
|.....||..|||... ..|..|......||..|..|   ...... .||..|||.||..|.....|.|.||.. ||||. ......|.||..|..|...
YCYTHHSENDRPDFFK-KNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIK

THGIKVNIIDFTLSRISKDSTTIYWDLEEDTTIFEGPDAPQFEVYREMRENCRYRYRYRGNWEKFSRRTNL
.||..|.||||..||..|| ..||||.. |.|.||. . .||.|||.||.||.       .|........ 
SHGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQH------FWFVHHAKNWK
Kinase aSWK213.AA Src 105-134 45 4.7e-09 26.87 In-house 1-31 (255) Show / Hide 
Range on Protein: 105-134
Range on HMM: 1-31/255
Sequence Identity: 45% (14 aa)

ARKVKKLGEGAYGEVFSTVWNG-RPVAIKVL
 . ..|||.| .|||.  .|||  .||.|.|
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTL
Kinase aSWK213.AA TKL-Unique 107-140 44 5.2e-09 28.11 In-house 1-33 (290) Show / Hide 
Range on Protein: 107-140
Range on HMM: 1-33/290
Sequence Identity: 44% (15 aa)

KVKKLGEGAYGEVFSTVWNGRPVAIKVLPFENNG
 ..|.|||.||.|. ..|.| |||||.. . |..
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NED
Kinase aSWK213.AA TKL 111-139 28 8.5e-09 27.82 In-house 1-39 (364) Show / Hide 
Range on Protein: 111-139
Range on HMM: 1-39/364
Sequence Identity: 28% (11 aa)

LGEGAYGEVFSTVWNG----------RPVAIKVLPFENN
.|.|..|||.  .|.|          ..||.|... .|.
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHND
Kinase aSWK213.AA MOS 105-134 33 1.4e-08 24.31 In-house 1-30 (299) Show / Hide 
Range on Protein: 105-134
Range on HMM: 1-30/299
Sequence Identity: 33% (10 aa)

ARKVKKLGEGAYGEVFSTVWNGRPVAIKVL
      .| |..|.|.   . |||||.|..
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQV
Kinase aSWK213.AA ARK 108-134 40 2.6e-08 26.6 In-house 4-30 (280) Show / Hide 
Range on Protein: 108-134
Range on HMM: 4-30/280
Sequence Identity: 40% (11 aa)

VKKLGEGAYGEVFSTVWNGRPVAIKVL
..|.|.|... |.   ..|..||||||
TCKIGSGSSCKVYKGKYRGKEVAIKVL
Kinase aSWK213.AA LISK 110-135 28 1.2e-07 20.75 In-house 1-28 (296) Show / Hide 
Range on Protein: 110-135
Range on HMM: 1-28/296
Sequence Identity: 28% (8 aa)

KLGEGAYGEVFSTVWN--GRPVAIKVLP
..|.|..|.|.   ..  |...||| ..
EIGKGFFGKVYKGTHRQTGQVMAIKMIH
Kinase aSWK213.AA CAMK 110-173 18 2.8e-07 18.77 In-house 1-99 (425) Show / Hide 
Range on Protein: 110-173
Range on HMM: 1-99/425
Sequence Identity: 18% (18 aa)

KLGEGAYGEVFSTVW--NG------------RPVAIKVLP-----------------FENNGCFYGNQSVEIPTTHAVLSEVIVMKELSA----LRDPN
.||.|..|.|.  .   ..            . ||||...                  .. .|  ... ..  . . |..|. .|| |..    |. ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN
Kinase aSWK213.AA SFK-Abl 109-132 58 3.5e-07 19.23 In-house 5-28 (251) Show / Hide 
Range on Protein: 109-132
Range on HMM: 5-28/251
Sequence Identity: 58% (14 aa)

KKLGEGAYGEVFSTVWNGRPVAIK
  |||| ||||.  .|| . ||||
HRLGEGQYGEVYKGIWNNHRVAIK
Kinase aSWK213.AA Pkinase_Tyr 105-134 44 8e-06 20.27 Pfam 1-36 (270) Show / Hide 
Range on Protein: 105-134
Range on HMM: 1-36/270
Sequence Identity: 44% (16 aa)

ARKVKKLGEGAYGEVFSTVWN------GRPVAIKVL
 .. |||||||.|||.  .|.      . |||.|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML
Kinase aSWK213.AA Pkinase 105-135 27 1.5e-05 20.67 Pfam 1-33 (293) Show / Hide 
Range on Protein: 105-135
Range on HMM: 1-33/293
Sequence Identity: 27% (9 aa)

ARKVKKLGEGAYGEVFSTVWNGRP--VAIKVLP
 ....|.|.|..|.|.  .. | .  ||.|...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK
Kinase aSWK213.AA MLK 105-132 24 1.8e-05 15.07 In-house 1-33 (291) Show / Hide 
Range on Protein: 105-132
Range on HMM: 1-33/291
Sequence Identity: 24% (8 aa)

ARKVKKLGEGAYGEVFSTVWNGRP-----VAIK
 .  ...|.|..|.|....| ..      ||.|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVK
Kinase aSWK213.AA S_TKc 105-424 10 5.6e-05 -103.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 105-424
Range on HMM: 1-231/231
Sequence Identity: 10% (38 aa)

ARKVKKLGEGAYGEVFSTVWNG--RPVAIKVLPFENNGCFYGNQSVEIPTTHAVLSEVIVMKELSALRDPNSWNSTPNFIEMISAQIVMGEYPKGLLRAW
 ....|.|.||.|.|.  ....  | ||||...                          ...|.. |.        || . .. .               
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------------EHIRREIQILKK-----HHPNIVKLYDVFQD------------

DAYDKLNESEHLRPDVYSSEHQNFILFVSANGGI---SLADFVLE----------SEDELFSIIHQLVLSMVAAEAALEFEHRDLNLSNVLIDRNGVEEL
                      ... .|    .    .| |.  .          .| .  ....|... .        . ||||  .|.|.|.      
----------------------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE------

SYTVHGQKIPLRTHGIKVNIIDFTLSRISKDS---------------TT----------IYWDLEEDTTIFEGPDAPQFEVYREMRENCRYRYRYRGNWE
                 . |.|| |.|.  ..               ..          | . .    . |.     ...... ..              
----------------HIKICDFGLARQL-TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--------------

KFSRRTNLMWIVYIANRLIDTEICPEGLFTDKRRKELKHLFDRLAEF-----GSCEESLT-D-----AEFY
                                  .|.|.. ... ..      .. | |. .      .. 
---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase aSWK213.AA TyrKc 105-382 15 9.8e-05 -146.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 105-382
Range on HMM: 1-280/280
Sequence Identity: 15% (56 aa)

ARKVKKLGEGAYGEVFSTVWNGRPVAIKVLPFENNGCFYGNQSVEIPTTHAVLSEVIVMKEL-----------SALRDP--NSWNSTPNFIEMISAQIVM
 .. |||||||.|||.  .|. ..||.|.|  .                 . ..|  .|..|            . ...  |       |..     |||
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-------FMYIEPLMIVM

GEYPKG-----LLRAWDAYDKLNESEHLRPDVYSSEHQNFILFVSANGGISLADFVLESEDELFSIIHQLVLSMVAAEAALEFEHRDLNLSNVLIDRNGV
   |.|     | .  .                                         . ..| |. .|    |   .    . ||||   |.|...|. 
EYMPHGDLKDYLRKHRPK---------------------------------------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH-

EELSYTVHGQKIPLRTHGIKVNIIDFTLSRISKDS------TTIYWD----LEE-------------DTT-----------------IFEGPDAPQFE--
                    | | || |||  .|       .  |       .              ..                  ||   . |  .  
-------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMI

----VYREMRENCRYRYRYRGNWE--------KFSRRTNLM---WIV---------YIANRL
      .|..|. . .|| .   .          .   ..|   |            |  ..
QQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase aSWK213.AA MLK 271-286 40 0.006081 6.2 In-house 150-171 (291) Show / Hide 
Range on Protein: 271-286
Range on HMM: 150-171/291
Sequence Identity: 40% (9 aa)

HRDLNLSNVLIDR------NGV
||||. .|.|||.      .|.
HRDLKSHNILIDEICHDMHHGT
Kinase aSWK213.AA TKL 271-285 53 0.038774 3.51 In-house 163-177 (364) Show / Hide 
Range on Protein: 271-285
Range on HMM: 163-177/364
Sequence Identity: 53% (8 aa)

HRDLNLSNVLIDRNG
||||. .|.|.|.|.
HRDLKSKNILVDENW