Gene air-2 (Nematode worm)

air-2

Species: Nematode worm
Alias: aSWK207, B0207.4, air-2, CE24761
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 5945610-5947016, WormBase Genetic Map location: I:0.454205,

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
air-2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
air-2.AA Protein Genbank 305 None Fasta, JSON

Protein domain

Protein domains of air-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase air-2.AA Aur 30-280 59 1.9e-234 626.53 In-house 1-257 (257) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-257/257
Sequence Identity: 59% (152 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVS--KRFSE
||||.|||||||| ||||| |  ||..|.||.||.|... ..||||.|||.||||||||||.|.|.||.|...|||.||||||||.||.|. .  |||.|
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

PTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIG-SQGELKIGDFGWSVHAP-SNKRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPP
..||||||.|..|| |||.||.|||||||||.|.. ..|..||.|||||||.| .|.|.|.|||.||.|||||.| .| . ||.|..||||||...|.||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FEH-EDQSKTYAAIK-AARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWI
||. |....|| .|| . ....|... |.|.||| ..|..||| |.||.|...|.||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase air-2.AA AGC 30-280 24 3.4e-107 277.65 In-house 1-395 (395) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-395/395
Sequence Identity: 24% (96 aa)

FEIGRPLGKGKFGSVYLARTKTGH------FHVAIKVLFKSQ---LISGGVEHQLERE------------IEIQSHLN----------HPNIIK-LYTYF
||. ...||| || |||.| |.|.         |.||| |.    ..    ...  .|             .| ...|          ||.|.| |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

WDAKK--IYLVLEYAP---------GG-EMYKQLT---VSKRFSEPTAAKYMYE-------IADALSYCHR-KNVIHRD-IKPENLLIGSQGELKIGDFG
 | ..  .|.|.||.|         || |.. .|     ..||.|..|  |. |       |. || | |. ...|||| .||||.|. ..| .|. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHAPS----------------------------------------------------NKRQTMCG--TMDYLPPEMVNGADHSDAVDLWA--IGVLCY
 .   ..                                                    .. .|.||  | .|..||..    .. |.| |.   |.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLVGKPPFEHE----------DQSKTYAAIK------AARFTYP----------DSVKKGARDLIGRLLVVDPKARCT----------LEQVKEHYWI
|.|.|.||| ..          .. ...  |.        . ..|          ... . |.||| .||..||. | .           |..|.| | 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase air-2.AA S_TKc 30-280 33 3.4e-98 333.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPG--GEMYKQLTVSKR---
.||.|..||| ||.||..| |  . .||||..            ...|||.| .. .||||.||| .| | ...|.|.||..|  |.... .   .|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNGADHSD-AVDLWAIGVLCYEFL
   |.| .|..|||.|..|| |||....||||.||||.|. .  ..||.||| . .       |.||| .|..||..    ..  ..| |..|.. ||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKE-------HYWI
.|.|||.  .. ...  |.           . |.|.| ..|..||. | |  .. .       | |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase air-2.AA CAMK 35-280 22 3.6e-98 316.95 In-house 1-425 (425) Show / Hide 
Range on Protein: 35-280
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

PLGKGKFGSVYLARTK-TG-----------HFHVAIKVLFKSQLIS-------------------------GGVEHQLEREIEIQSH-------LNHPNI
 ||.| || |.|.. | |.           . .||||.. |..| .                         .  .....||||| ..       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYT-------------------YFWD-AKKIYLVL---EYAPGGEM----YKQLTVS---------------KRFSEPTAAKYMYEIADALSYCHRKN
||||                    .| .  |..|.|.   ||..|||.    .  ..                 .||.|  |..|.  |..|. ||| .|
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDIKPENLLIGSQ-----------------GELKIGDFGWSVHAPSNK-------------------------RQTMCGTMDYLP-PEMVNG-----
..|||.||||.|. .                  . .|| ||| . . ....                          .|.|||  | . ||..||     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------ADHSDAVDLWAIGVLCYEFLVGKPPFEHE-------------DQSKTYAAIKAARFTYPDSVKKG------------------------AR
           .. ..| |..||..|  |.|.|||...             ......  |.......|..  ..                        ..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIGRLLVVDPKARCTLEQVKEHYWI
||| ..|.|||. | |.||...| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase air-2.AA CAMKL 30-280 33 3.4e-87 278.29 In-house 1-297 (297) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-297/297
Sequence Identity: 33% (99 aa)

FEIGRPLGKGKFGSVYLART-KTGHFHVAIKVLFKSQLI-SGGVEHQ-----------LEREIEIQSHLN---HPNIIKLYTYFWDAKK------IYLVL
..||. |||| || | ||.  .|   .||||.. |. .     ..             ..|||.|...||   ||||||||  . . ..      ||||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAPGGE--MYKQLTVS----KRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQG--ELKIGDFGWS-----V-HAPSNKRQTMCGTMDYL
||..|||  ..  .       .|..|. | .|   | .|..|||.....||||||||.|. ..|   .|| ||| |     .   | .|  | ||.  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMVNG--A-DHSDAVDLWAIGVLCYEFLVGKPPFEHE--------DQSKTYAAIKAARFTYP--DSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWI
.||...|     .  .|| |..||. |  ..|. ||. .        .. . |  |.   . .|   .|   .|||| ..|.|.|. | |..|...| | 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase air-2.AA Pkinase 30-280 32 5.3e-86 296.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLE-REIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGG----EMYKQLT--VS
..|||..|.| ||.||... |     ||.|.. |.   |.  .. .  .||.|  .||||||..|| .| | ..||.|.||..||    . .  ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRF--SEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGEL----KIGDFGWSV---HAPSNKRQTMCGTMDYLPPEMVN-GADHSDAVDLWAI
..|  || .. .|||.|. .| |||....||||.||||.|| ..|..    ||.||| .    . ..   .| ||| .|..|| .. | ... .|| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLCYEFLVGKPPFEHE------DQSKTYAAIKAARFTYPDSVK---------------------KGARDLIGRLLVVDPKARCTLEQVKEHYWI
|...||.| |.||| ..      || . .. |. ... .. . .                     . ..|.| ..| .||| |.| ||...| |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase air-2.AA PLK 30-280 36 7.7e-82 266.29 In-house 1-258 (258) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-258/258
Sequence Identity: 36% (94 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVS-KRFSEP
.|.|..|||| |  .| ..    .  .||||  || ... .    ...||||.. |.|||| |....| |.  .|.||||......   .    ||..||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

TAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSN--KRQTMCGTMDYLPPEMVNGAD--HSDAVDLWAIGVLCYEFLVGKP
 .  ||| |. .| | |....||||.|. ||.. .  ..|||||| ..    .  .. |||||  |  || ..|    ||  || |..|.  | .|.|||
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFEHEDQSKTYAAIKAARFTYPDS--VKKGARDLIGRLLVVDPKARCTLEQVKEHYWI
||| .|   ||  || .....|..  . . |.||| ..|  .|  | |..|. .| . 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase air-2.AA MARK 30-280 37 2.1e-81 265.88 In-house 1-262 (262) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-262/262
Sequence Identity: 37% (99 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFW--DAKK-IYLVLEYAPGGEMYKQLTVS--KR
..... .|.| .. |.||. |  . .||||.. | .|        ..||||| ..|.|||||||. ..   . .. |||..|||.|||.|  .      |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQG--ELKIGDFGWSVHA-PSNKRQTMCGTMDYLPPEMVNGADHS-DAVDLWAIGVLCYEFL
 .|. | ..   |  |..|||.||..||||||||.|| ..|    || |||.|..  | .|  | |||  | .||.... .    .|| |. ||. |  .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGKPPFE--HEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWI
.|. ||.    |. . |  | . ....|. | |..|.|| |||.|.|. | |.|.. .| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase air-2.AA RSK 33-280 32 5.3e-76 258.81 In-house 1-278 (278) Show / Hide 
Range on Protein: 33-280
Range on HMM: 1-278/278
Sequence Identity: 32% (92 aa)

GRPLGKGKFGSVYLARTKTGHFHV---AIKVLFKSQLISGG--VEHQLEREIEIQSHLN-HPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKR--
 . ||.| .|.|.| | .|.| .    | ||| |. ..     ..| .. |..| .. . ||.|..|.  | . .|.||..|| .|||... |   |.  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMT-ERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGS---QGELKIGDFGWSVH-APS--NKRQTMCGTMDYLPPEMVN----GADHSDAVDLWAIG
 ||| .|. ||.||. |... | . .||||.|||| |  .   .|..|. ||| .    ..  .. .| |.| .|..|||..    .  |. |.|.|  |
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VLCYEFLVGKPPFEH---EDQSKTYAAIKAAR--FTYP--DSVKKGARDLIGRLLVVDPKARCT-----LEQVKEHYWI
|| || |.|.||| .   ...... . |. ..  .| |  ... . |.||| ..| .||. | .     .|..|.| |.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase air-2.AA PKA 30-280 38 1.2e-75 257.67 In-house 1-263 (263) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-263/263
Sequence Identity: 38% (101 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNII-KLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEP
||| . ||.| || |.|.| |..  ..|.|.| |.. .    ..    |. | . ..||.|. |.|  | |....|.|.||.||||| . |  |.|||.|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TAAKYMY-EIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNGA-DHSDAVDLWAIGVLCYEFLVGKPPF
.|  |   .|  || | | .| |.|| ||||.|| ..| .||.||| .    .   .|.||| .||.||....   |  .|| || |.| ||.|.|.|||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

EHE--DQSKTYAAIKAARFTYPDSVKKGA---RDLIGRLLVVDPKARC-TLEQ----VKEHYWI
. .  |. ..|  | ...  .| .. . |   .||| .||.||.. |  ....    .|.| | 
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase air-2.AA Ciliate-E2 30-280 26 9.6e-75 254.62 In-house 1-365 (365) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

FEIGRPLGKGKFGSVYLART-KTGH----------------------FHVAIKVLFKSQLISGGVEHQLEREIE----------IQSHLNHPNIIKLYTY
... . .|.| |||||...  |...                      . .|.|.. |.|...   | .. |||.          |...||||||||.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FW--DAKKIYLVLEYAPGGEMYKQLTVS-----------KRFSEPTAAKYMYEIAD---------------ALSYCHRKN-VIHRDIKPENLLIGSQGEL
|   | ..||||.||. ||.... .  .           |.|.|  ....|..|..               || |.| || .|||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDFG-------------------WSVHAPS---------------NKRQTMCGTMDYLPPEMVNGAD---------HSDAVDLWAIGVLCYEFLVGKP
|| |||                   |     .               |  .| |||  |..||..|| .         .. ..|.|..||. ||.| |||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFEHEDQSKTYAAIKAARFTYP------------------DSVKKGARDLIGR----LLVVDPKARCT-LEQVKEHYWI
||        .  ||   . .|                  ... . . ||| .    .|..||. | |  ||...| |.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase air-2.AA Ciliate-E2-Unclassified 30-280 24 1.1e-73 251.12 In-house 1-352 (352) Show / Hide 
Range on Protein: 30-280
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

FEIGRPLGKGKFGSVYLART-KTGHFHVAIKVLFKSQLIS-----GGVEHQLEREIEIQSH------------------LNHPNIIKLYTYFWDAKKIYL
..|.. .|.| ||.||...  |.. .  |.| . |.| ..           .  ..|....                  ..||.|.|.. .| | ..||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VLEYAPGG-----------------EMYKQLTVSKRFSEPTAA-----KYMYEIADALSYCHRKN-VIHRDIKPENLLIGSQG---ELKIGDFGWSVHA-
|.||..||                 ......  .|.|.|  |.     .|...| ..|.|.|.|| .|||||||||.|. ..|   ..|| ||| | .  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------PSNKRQTMCGTMDYL----PPEMVNGADHSDA----VDLWAIGVLCYEFLVGKPPFEHEDQSK----------------TYAAI
                .... .|.|||  |.    .||.  |  ...     .| |. ||..||.| |..||. ... .                 |  |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KAARFTYP--------DSVKKGARDLIG----RLLVVDPKARCTLEQVKEHYWI
|.  . .|        . . . | |.|     ..|...|. | |.||...| |.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase air-2.AA Pkinase_Tyr 30-173 30 1e-26 91.12 Pfam 1-156 (270) Show / Hide 
Range on Protein: 30-173
Range on HMM: 1-156/270
Sequence Identity: 30% (48 aa)

FEIGRPLGKGKFGSVYLARTK----TGHFHVAIKVLFKSQLISGGVE---HQLEREIEIQSHL-NHPNIIKLYTYFW-DAKK--IYLVLEYAPGGEMYKQ
 ..|. ||.| ||.||... |     .. .||.|.| |    .   .     . ||..| ..| .||||..||     . .   ||.|.||.|.| ... 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LTV----SKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFG
|       .... ..  .. ..||....| ..|| ||||.   | |.....  ||.|||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase air-2.AA TyrKc 30-278 23 8.9e-18 64.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-278
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHL--NHPNIIKLYTYFWDA-------KKIYLVLEYAPGGEMYKQLT
 . |. || | || ||... |     ||.|.| ..       .  . ||..| ..|  .||||..|| .  .        . ...|.||.|.|   . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

VSKR-FSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSN------KRQTMC----GTMD-----YLPPEMVNGADHS
 ... .. ..  .... ||.  .| |.||.||||.   | |.|...  ||.||| |    .       |   .     |. .      ..||  |    .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

DAVDLWAIGVLCYEFL-VGKPPFEH-----EDQSKTYAAIKAA-RFTYPDS--------VKKGARDLIGRLLVVDPKARCTLEQVKEHY
 . | |. ||...| .  |..| .       . .  .. .|.  |   |..          .   ... .    ||. |.| ....|  
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF