Gene TTBK1 (Mouse)

TTBK1

Species: Mouse
Alias: TTBK1
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
TTBK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
TTBK1.AA Protein Sugen 1308 None Fasta, JSON
TTBK1.NA RNA Sugen 4224 None Fasta, JSON

Protein domain

Protein domains of TTBK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TTBK1.AA TTBK 34-289 83 1.3e-220 739.18 In-house 1-257 (257) Show / Hide 
Range on Protein: 34-289
Range on HMM: 1-257/257
Sequence Identity: 83% (215 aa)

WKVLKKIGGGGFGEIYEAMDLLTR-ENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL
|||.||||||||||||||.|.... |.||.||||||||||||||||||||||||.||||||||||||.||||.||||||.|||||||.||||.|.|||||
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEF
|||.|||.|||.||||||||||||||||||||.|||.||||||||||||||||..|.|||||.||||||||||||.|||.||||||||||||||||||||
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF

AVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLI
..|||||||||||.|||..||||.|||||||.|.|||.|.|||.||.|...||||||
VQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase TTBK1.AA CK1 34-289 34 1.6e-125 423.32 In-house 1-339 (339) Show / Hide 
Range on Protein: 34-289
Range on HMM: 1-339/339
Sequence Identity: 34% (116 aa)

WKVLKKIGGGGFG-EIYEA-----MDLLTR-----ENVALKVESAQQPKQ-VLKMEVAVLKKL---------------------QGKDHVCRFIGCGRNE
||| ||||.|||| .||..     .|. .      | .|.|||.... .|  ..||.....|.                     .|. |.|... .|...
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

K-FNYVVMQLQGRNLADLRR--SQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPS------------TYRKCYMLDFGLAR-QYT
. .||.||.| |.|| |||.   .... |...|.|... |.||..| .|. ||.||||||.||.||| .|            ..|. ||.|||.|| .|.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

NTTGDV------------RPPRN---VAGFRG-TVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQ--LPWRKIKDKEQ-----VGMIKEKYEHRMLL
.  |..            ||||.    .|||| |.||.|.|.|...|.||.|||||.||||.|. .|.  |||...||...     |.. |... .....
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

------------KHMPSEFHLFLDHIASLDYFTKPDYQLI
            ...|.||  ....| ||.|...|||. |
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase TTBK1.AA Worm6 34-289 41 6.2e-113 381.49 In-house 1-279 (279) Show / Hide 
Range on Protein: 34-289
Range on HMM: 1-279/279
Sequence Identity: 41% (115 aa)

WKVLKKIGGGGFGEIYEAMDLLTREN--VALKVES--AQQPKQVLKMEVAVLKKLQGKD--HVCRFIGCGRNEK--FNYVVMQLQGRNLADLRRSQPRGT
|||.|||| |||| .|.. |  . ..  .|.|.|.  .. ..|.||||..|||..  .   |.|... .|. ..  |||.||.| |.||.|||. .| . 
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRL----PSTYRKCYMLDFGLAR--QYTNTTGDVRPPR-NVAGFRGTVRYASVNAHKNREMGR
|...|.|... | ||.||  |..||.|||.||.||. ||        ... ||||||..|  .| |. ...|.|| ...|||||||||....||..|..|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

HDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEK--YEH-----RMLLKHMPS-EFHLFLDHIASLDYFTKPDYQLI
 ||. | |||.||. ||.||||..||. .|. .|..  ..      ||...  |  ||   .| | ...|...|||. |
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase TTBK1.AA TTBKL 34-293 38 1e-111 377.46 In-house 1-288 (288) Show / Hide 
Range on Protein: 34-293
Range on HMM: 1-288/288
Sequence Identity: 38% (111 aa)

WKVLKKIGGGGFGEIYEAMDLLT-RENVALKVESAQQPK--QVLKMEVAVLKKLQ--GKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGT-FT
|.. |.||.||||..|...|. .  .  |.|.|. .. .  ...|||| ||.|||  |. |.......|.....|..||.| |.|| |||.  |..  |.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPST---YRKCYMLDFGLARQYTNTTGDV-----------RPPRN---VAGFRGTVRYASVNA
 .|..|.| |.|...  .|..||.|||.||.|...|   ..    |  | .|||.|||| .  |.            |.|||    |.||||.||.|.|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKH------MPSEFHLFLDHIASLDYFTKPDYQLIMSVF
|  .| ||||||||..||..|...| |||. ..||....  |..  .  | |       .||||  |  |. ||.|   |||. |. .|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase TTBK1.AA CK1 34-287 35 2.7e-66 226.54 In-house 1-271 (271) Show / Hide 
Range on Protein: 34-287
Range on HMM: 1-271/271
Sequence Identity: 35% (96 aa)

WKVLKKIGGGGFGEIYEAMDLLTREN---VALKVESAQQPKQVLKMEVAVLKKLQG------KDHVCRFIGCGRN--EKFNYVVMQLQGRNLADLRRSQP
 .| .||| | ||.||..... | ..   || |.|.. .  . |. |. ..| |||        .. . . ||..  ...|..|| | |..| ||     
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN

RGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT-NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDD
|  |.| |.| .. |... || .|. .|.|||||| || |||      ..|. ||||| .|    |.   | |.  .. ||.||||.|.|  .| .| ||
R-KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD

LWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRMLLKH-MPSEFHLFLDHIASLDYFTKPDYQ
. || |.|. |. |.|||  .| .      |. ...| .. . .| |   |.||. .| .. .|... ||||.
MESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase TTBK1.AA CK1-Unclassified 34-256 38 7.6e-66 193.32 In-house 1-229 (244) Show / Hide 
Range on Protein: 34-256
Range on HMM: 1-229/244
Sequence Identity: 38% (91 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD-------HVCRFIGCGRNEK--FNYVVMQLQGRNLADLRRSQPRG
 .|..||| | |||||..... | |.||.|.|.. .    |. |. ... ||.         .. . . ||..|.  .|..|| | |..| ||      .
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFN-MCNR

TFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDL
 |.| |.| .. |... || .|. .|.|||||| || ||.|   . ..|. ||||.  |     ||   | |.  .. || ||||.|||.  | .| |||
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL

WSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYE
 || | |. |. |.|||  || ...    |||||
ESLGYVLIYFLKGSLPWQNIKANNK----KEKYE
Kinase TTBK1.AA CK1-D 34-289 37 1.9e-52 180.53 In-house 1-261 (261) Show / Hide 
Range on Protein: 34-289
Range on HMM: 1-261/261
Sequence Identity: 37% (98 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLR
... .|||.| ||.||   .. | | ||.|.|...     |..|  . | .||   . .   ||..  .| .||.| |  | ||     |  | | | | 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHR-KFSLKTVLM

LGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTT-GDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEF
|. |..  || ||.  |.|||||| || || |       |..|||||..|  .      | |      || ||||.| |.  |  | ||| || |.|. |
LADQMICRIEYIHCRNFIHRDIKPDNFLMG-LGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYF

AVGQLPWRKIK---DKEQVGMIKEK---YEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLI
. | |||  .|    ...   | ||    .   | | .||||  ....  .| .  ||||  .
NRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase TTBK1.AA CK1-A 34-289 35 2e-51 177.13 In-house 1-261 (261) Show / Hide 
Range on Protein: 34-289
Range on HMM: 1-261/261
Sequence Identity: 35% (93 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLR
.....||| | ||.|| .. .   |.||.|.||..     |  |  | . |||   . .    |..  .| .||.| |  | ||     |  ||. | | 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKR-RFTMKTVLM

LGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVR-PPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEF
|  |..  || .|  .|.|||||| || || .     | ...|||||..|         | |.     ||.||||.|||   |  | ||. |. |... |
LADQMIMRIEYVHEKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYF

AVGQLPWRKIK---DKEQVGMIKEKYEH---RMLLKHMPSEFHLFLDHIASLDYFTKPDYQLI
  |.|||  .|    | .   | ||       .| | .|.|| ... .. .| .  .|||  .
NRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase TTBK1.AA CK1-G 34-289 33 1.9e-41 138.2 In-house 1-266 (266) Show / Hide 
Range on Protein: 34-289
Range on HMM: 1-266/266
Sequence Identity: 33% (90 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD----HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLS
..| |||| | |||..|   ... | || | |  .     |. |    | | |.     .|  |  ||   |.|  || | |  | ||     | .|.. 
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCG---KYNIMVMDLLGPSLEDLFDWCDR-KFSVK

TTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPS-TYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFY
|.. . .|... .|..||   . ||.|| ||  ||  . . .. .. |||.|.||    |.   | |      || || |.| |  ||  | ||. .|  
TVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGH

MLVEFAVGQLPWR-----KIKDK-EQVGMIKEKYEHRMLLKH--MPSEFHLFLDHIASLDYFTKPDYQLI
|   |  |.|||        | . . .|. | |     |..   .| .|  .|  . .||.| .|||  .
MFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase TTBK1.AA Dual 34-293 26 2.9e-38 126.19 In-house 1-282 (282) Show / Hide 
Range on Protein: 34-293
Range on HMM: 1-282/282
Sequence Identity: 26% (76 aa)

WKVLKKIGGGGFGEIYEAMDLLT----RENVALKVESAQQPKQVL--KMEVAVLKKLQG---------KDHVCRFIGCGRNE--KFNYVVMQLQGRNLAD
||| . .| |||...|   .        . ..||.||    |  |  | |. | .|  .           ..  |.  |  |  | .|.|| . |  | .
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE

LRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYASVNAHKNRE
 ||    | .. ..    . | |..|   ||.|.|||.|||.||. | |     . ||.||...| |    .. .|..|    . |. |||.    . ..
IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCG-LGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKD

MGRHDDLWSLFYMLVE-FAVGQ-LPWRKIKDKEQVGMIKEKYEHRMLLK---HMPSEFHLFLDHIASLDYFTKPDYQLIMSVF
 || ||| .  ||.   .  .  ..|||  |   .   |.      . .   | | ..   .. . .. | . |||  ..   
QGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase TTBK1.AA S_TKc 34-308 20 7.9e-23 83.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-308
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGR---NLADLRRSQPRGT----F
...|.||| |.||. | . .  | . ||.|. .     . .. |...|||  . ......... .. .. |.|| . .    .| |. ....|.     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGR-HDDLWSL
.  .. .. .||.. .| .|| |..|||.||.|  . .           |||||||.               | ||  | .         |.   | ||.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

FYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER---GIAE-------NEAF
  .| |...|. |..      |. |. .|                           ...  ..|.  ..   ..|    . .        . |
GCILYEMLCGYPPFP------QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase TTBK1.AA Pkinase 34-160 25 1.4e-22 80.93 Pfam 1-139 (293) Show / Hide 
Range on Protein: 34-160
Range on HMM: 1-139/293
Sequence Identity: 25% (36 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKM------EVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRN--LADLR----RSQ
.....||| |.||. |....  |.. ||.|. . .  |   ..      |....|.| . ....|.... ....  |.|| . .    ..||     . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-W

PRGTF--TLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNF
 .|.|  .  .  .  .|||. .| .|| |..|||.||.|.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI
Kinase TTBK1.AA TyrKc 34-293 19 8.3e-09 -80.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-293
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

WKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKL-QGKDHVCRFIGCGRNE-------KFNYVVMQL-QGRNLADLRRSQPRG
 . .||.| | |||.|...     ..|| |.  .   .. .  |  ...||    ... |..|. . .       .  ..|| .  . .| |  |.  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

TFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT--TGDVRPPRNVA----GFR--GTVRYASVNAHKNREM
 ..... |    || .  | .|| .. |||.   |   |.       .   ||||.|  ..   .| ..    ..    | .    .|  .  . . .. 
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

GRHDDLWSLFYMLVE-FAVGQLPWRK-----IKDKEQVGMIKEKYEHRMLLK-------HMPSEFHLFLDHIASLDYFTKPDYQLIMSVF
    | ||   .. | |  || |.       ....| .  .|. |  .           ..|.| .         |    |  . | . |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TTBK1.AA Pkinase 176-240 27 2e-06 24.18 Pfam 155-213 (293) Show / Hide 
Range on Protein: 176-240
Range on HMM: 155-213/293
Sequence Identity: 27% (18 aa)

DFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHK-NREMGRHDDLWSLFYMLVEFAVGQLPWR
|||||.|.        . .   .| || .|..   .. ... |.  | ||.  .| |.. |..|..
DFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP