Gene TSSK4 (Mouse)

TSSK4

Species: Mouse
Alias: TSSK4, 4933424F08Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: TSSK

Sequence

Name Sequence Type Origin Length Description Download
TSSK4.NA RNA Sugen 1237 None Fasta, JSON
TSSK4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 269 Kinase domain by global Sugen HMM Fasta, JSON
TSSK4.AA Protein Sugen 328 None Fasta, JSON

Protein domain

Protein domains of TSSK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TSSK4.AA TSSK 25-293 46 5.69999999999e-184 608.71 In-house 1-289 (289) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-289/289
Sequence Identity: 46% (139 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVM----------------VAVKIISKKKASEDYLNKFLPREIQVMKV-LRHKYLINFYQAIETTS-RVYIILELAQ
|.|||.||||||..||.||..|.|..                ||.|||..|||..||||||||||||.|.. |.|...|.||...||.. ..|...|.|.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGDVLEWIQRY------GACAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCG
.||.||.|||.      ||. | .|.|||.||. ...|.||...||||||.||.||||..|.|..|||||...|...|...          .|||.|.||
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRC----------CHLSKTFCG

SFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDD--TNLKKLLRETQ-KEVTFPA--NLTISQECKNLILQLLR-QSTKRATILDVLRDPWM
|.|||.||||.| ||.|...|.||||||||..|....||||  .|..|.|...| ..|.||.  ...||||||.||...|. . ..|..| ......||
SYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase TSSK4.AA CAMK 30-293 24 7.29999999999e-109 352.01 In-house 1-425 (425) Show / Hide 
Range on Protein: 30-293
Range on HMM: 1-425/425
Sequence Identity: 24% (103 aa)

IIGHGSYGTVYEAYYTKQK------------VMVAVKIISKKKASE-------------------------DYLNKFLPREIQVMKV-------LRHKYL
..|.||.|.|.... .. .            . ||.|||.|||...                         ..  |...|||..||        |.|. .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INFYQAIE------------TTSR--------VYIIL---ELAQGG----DVLEWIQRY---------------GACAETLAGKWFSQMALGIAYLHSKG
|..|...|            | |.        .|...   |...||    |....|..                |   |  | ..| |.. ...|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKLENLLLDKRE-----------------NVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHL----------SQTYCGSFAYAC-PEILLG---
|||||||.||.|||...                 |.||.|||||.......  .  ..| ... . |            .|.||. .|.. ||.|.|   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

----------LPYNPFLSDTWSMGVILYTLVVARLPFDDT-------------NLKKLLRETQKEV-TFP-----------------------ANLTISQ
           || .. .| ||.|||||.... ..||..              |...|..  .|   .||                        . ..||
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQ

ECKNLILQLLRQ-STKRATILDVLRDPWM
|||.|| ..|.   .||.|| ..|..|||
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TSSK4.AA CAMKL 25-293 32 1.9e-104 334.25 In-house 1-297 (297) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-297/297
Sequence Identity: 32% (102 aa)

YEVGKIIGHGSYGTVYEAYYTKQ-KVMVAVKIISKKKAS-EDYLNKF-----------LPREIQVMKVLR---HKYLINFYQAIETTSR------VYIIL
|..|| .|.||.|.|  |  ..  ...||.||| |||.. ... .|            . |||| || |.   |.  | .|. ||| .       .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELAQGGD--VLEWIQRYGA----CAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRE--NVKISDFGFAKM---VPSSQPVHSSPSYRQMNSL
|...||.   ...|.. |       |  | . | |.  ...|.||.||||||.|.||.|||..   |.||.||||. |   .               .  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC--------------IFGP

SHLSQTYCGSFAYACPEILLG--LPYNPFLSDTWSMGVILYTLVVARLPFDDTNL--------KKLLRETQKEVTFPANLTISQECKNLILQLLRQ-STK
 ..  | ||| .|..|||..|   ||. .  | ||.|||||..|. .||||| ..        ...... .    .|  . .| .|..|| ..|    .|
GQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEK

RATILDVLRDPWM
|.|| .....|||
RPTIHQIMNHPWM
Kinase TSSK4.AA MARK 25-293 36 1.5e-94 309.5 In-house 1-262 (262) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-262/262
Sequence Identity: 36% (101 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIE--TTSR-VYIILELAQGGDVLEWIQRY--GA
|...| ||||||..|. |  .. .. ||.||. |.| ..    | . |||..|| | |.. | ....||  |... .|.|.|.| ||.....|.    | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

CAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRE--NVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILLGLPYNP
  | .| . |.|.  .. |.|||.|||||.|.||.|.|..   |.||.||||.  .|. |                   | ||. .|..|||.|. ||. 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK----------------LNTFCGTPPYMAPEIFLKKPYDG

FLSDTWSMGVILYTLVVARLPFDDTN--LKKLLRETQKEVTF-PANLTISQECKNLILQLLR-QSTKRATILDVLRDPWM
.  |.||.||.||..|. ..|||...  .|.| .. ....   | .  .| ||.||| .||     .|.|| .....|||
PKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase TSSK4.AA S_TKc 25-293 28 4.2e-87 296.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-231/231
Sequence Identity: 28% (80 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQG--GDVLEWIQRYGA---
||....||.|..|.|| .. .| .  ||.|||.          . . ||||..|  .|......| .... ...|...|.. |  ||... |...|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---CAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILLGLPYN
     |  | ... |......|.||.||.||||| ||.|||.  ..||.|||.|. .                       |.||.  |  ||.|   .|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------TTFCGTPWYMAPEVL---GYG

PFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEVTFPANLTISQECKNLILQLLR-QSTKRATILDVLR-------DPWM
.. .| || |.||| ... . ||.  .......              |.|.|..| ..|.   .|| |. ..|.       .||.
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TSSK4.AA Pkinase 25-293 29 4.1e-77 267.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASE--DYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGG----DVLEWIQ--R
|..|..|| ||.|.||...  .   .||||||.|.....  |. .  | .|||.|| |.|.. . .| . |. ...|...|...||    |  ..|.  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YGAC--AETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENV----KISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEIL
.|.    |  . ... |.. |..|.||.||.|||||.||.|.|.. ..    ||.|||.|| .               .  ..  .|.||.  |. ||..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------------Y-NNS-MTTFCGTPWYMAPEVI

LGLPYNPFLSDTWSMGVILYTLVVARLPFDDT------NLKKLLRETQK-EVTFPANLTIS-------------------QECKNLILQLLRQS-TKRAT
.| .| .  .| ||.|.||| ..  |.||..       . ....... . .. |.   ..|                   .||| .|  .|..  .|| |
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

ILDVLRDPWM
. ..| .||.
AEQILQHPWF
Kinase TSSK4.AA AMPK 25-293 36 9.3e-74 218.37 In-house 1-254 (254) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-254/254
Sequence Identity: 36% (99 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAI-ETTSRVYIILELAQGGDVLEWIQRYGACAET
| .|| || |..| |  .. .  .  ||.||. |.|  ..   . . |||. .|..||  .|  |. | ||..  ....| ..||.  ..| . |   | 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

LAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILLGLPYNPFLSDTW
 | . | |.  |. |.|  .|||||||.||||||.  |.|| |||  .|            .   . |.    | |||  || ||.  | .|.    |.|
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNM------------MKDGEFLK----TACGSPCYAAPEMISGKLYCGPEVDIW

SMGVILYTLVVARLPFDDTNLKKLLRETQ-KEVTFPANLTISQECKNLILQLLRQS-TKRATILDVLRDPWM
| ||||| .. ..||||| |  .| .     |.. |..|  |.|.|.|| ..|.   .||.|| |.  .|| 
SCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFL--SPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase TSSK4.AA ULK 25-293 26 6.7e-70 238.54 In-house 1-324 (324) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-324/324
Sequence Identity: 26% (90 aa)

YEVGKIIGHGSYG-TVYEAY-YTKQ--KVMVAVKIISKKKASE-------DYLNKFLPREIQVMKVLR---HKY--LINFYQAIETT--SRVYIILELAQ
|.. ...|.||.| .||...   ..  .. ||.|.|.||| ..       .|. ..| .|||.|| |    |..   . .|   ||.    .|||.|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDVLEWIQRYGACAETL----------AGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKREN------------VKISDFGFAKMVPS-SQPVHSSP
|||  . |.... . |            | . | | . |  .||...|.|||.|..|.|. .               .||.||||||.| . ..      
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SYR-QMNSLSHLSQTYC---GSFAYACPEILLGL----PYNPFLSDTWSMGVILYTLVVARLP----FDDTNLK--KLLR--------ETQKEVTFP---
..  .               |.  | .|.|| |.    ||. . .| ||.|.|.| ..  . |    | |..|.  ||..        . .. . ||   
TCVNE-----------KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP

ANLTISQECKNLILQLL-RQSTKRATILDVLRDPWM
..  ||.|||.|| ..| .. ..| .. ...  ||.
KDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase TSSK4.AA ULK 25-293 26 5.1e-68 232.29 In-house 1-329 (329) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-329/329
Sequence Identity: 26% (89 aa)

YEVGKIIGHGSYGTVYEAY-YTKQ---KVMVAVKIIS----KKKASE---DYLNKFLPREIQVMKVLR----HKY----LINFYQAIETT--SRVYIILE
|.. ...|.||.|.||...   ..   ...||.|.|.    ..|  |   .|. ..| .||..|| |     ||.     . .|   ||.    .|||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAQGGDVLEWIQRYGACAETL----------AGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKREN------------VKISDFGFAKMVPSS-QPVH
. .|||  . |.... . |.           | . | | . |  .||...|.|||.|..| |...               .||.||||||.| .. .   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

SSPSYR-QMNSLSHLSQT-YCGSFAYACPEILLGL----PYNPFLSDTWSMGVILYTLVVARLP----FDDTN---LKKLLRET--------QKEVTFP-
   ..  .         . .||.  | .|.|| |.    ||. . .| ||.|.|.| ... . |    | |..   ..||.. .        ..   || 
MMMTCVNE---------KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPK

--ANLTISQECKNLILQLL-RQSTKRATILDVLRDPWM
  .. .||.|||.|| ..| .. ..| .. ...  ||.
DGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TSSK4.AA Ciliate-E2 25-293 21 3.8e-67 229.37 In-house 1-365 (365) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YEVGKIIGHGSYGTVYEA--YYTKQKV---------------------MVAVKIISKK----KASEDYLNK-------FLPREIQVMKVLRHKYLINFYQ
|.. |.|| |..|.||..  . .....                     ..|.||..|.    . .|.....       ..  | .... | |...|..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE

AIE--TTSRVYIILELAQGGDVLEWIQ---RYGACA--------ETLAGKWFSQMAL---------------GIAYLHSKG-IVHRDLKLENLLLDKREN
. .  ... .|...|..|||| ...|.       .         |  ... . | .                .. |||||. |.|||.|.||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKISDFGFAKMVPSSQPVHSSPSYRQMNSLS-----------------HLSQTYCGSFAYACPEILLGLPY--------NPFLSDTWSMGVILYTLVVAR
.||.|||..| .  ..  ..    .. . .                  .. .|.||.  | .|||| | .|          . .| ||.||||| ..  .
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFDDTNLKKLLRETQKEVTFP----------------ANLTISQECKNLILQ-----LLRQSTKRAT-ILDVLRDPWM
.||       .    |... ||                 .. .|||||.|| .     | ..  || | . ..|  ||.
PPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TSSK4.AA Ciliate-E2-Unclassified 25-293 22 4.1e-61 209.36 In-house 1-352 (352) Show / Hide 
Range on Protein: 25-293
Range on HMM: 1-352/352
Sequence Identity: 22% (84 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMV-----AVKIISKKKASEDYLNKFLPREIQVMKVLR-------------------HKYLINFYQAIETTSRVYI
|...|.||.|..|.||...  |||  .     . ||...|. .  . .  . .|.. |. .                    | ...... . ...  .||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILELAQGGDVLEWIQRYGA-------------------CAETL---AGKWFSQMALGIAYLHSKG-IVHRDLKLENLLLDKRE---NVKISDFGFAK---
..|...||| ...|. ..                    . ...   | ..| |  .|. |||.|. |.|||.|.||.|.|.     ..||.|||..|   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

---------MVPSSQPVHSSPSYRQMNSL-SHLSQTYCGSFAYA----CPEILLGLPYNP---FLSDTWSMGVILYTLVVARLPFDDTNLKK--------
                        .|. . .....| ||.  |      ||.| |  |.    . .| ||.||||| ..  ..||.|.| ..        
QNNNCDTNQQ-------------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQW

--------LLRET-QKEVTFPANL------TISQECKNLIL----QLLRQSTK-RATILDVLRDPWM
        |...  ||.. ||         ..|.|.|..|     ..|    . | |. ..|  ||.
INNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TSSK4.AA QIK 25-169 36 6.7e-47 162.13 In-house 1-164 (272) Show / Hide 
Range on Protein: 25-169
Range on HMM: 1-164/272
Sequence Identity: 36% (60 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGA-----
|.... || | ...|  |     |  ||.||| | .  |..|.|   ||.|.||.|.| . |  || .|| .  ||. | ...|.  . .  .|      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCY-REVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------CAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGF
                ||  | .||.|......|.|...||||||| ||.|||.  |.|| ||||
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGF
Kinase TSSK4.AA Pkinase_Tyr 25-173 30 9.7e-32 108.12 Pfam 1-161 (270) Show / Hide 
Range on Protein: 25-173
Range on HMM: 1-161/270
Sequence Identity: 30% (50 aa)

YEVGKIIGHGSYGTVYEAYYT----KQKVMVAVKIISKKKASEDY--LNKFLPREIQVMKVL-RHKYLINFYQAIE-TTSR--VYIILELAQGGDVLEWI
 . || .|.|..|.||.....    ..|. ||||.. | .|...   . .|.  |...|| | .|. ....| ..        .||..|....|| |.  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QRYGACAETLAGKWFSQMALGIA----YLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMV
..     . |  |.  ||.. ||    ||.||...||||   | |...   |||.||| |. .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase TSSK4.AA QIK 196-293 39 8.5e-21 75.42 In-house 175-272 (272) Show / Hide 
Range on Protein: 196-293
Range on HMM: 175-272/272
Sequence Identity: 39% (39 aa)

QTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEVTFPANLTISQECKNLILQLLR-QSTKRATILDVLRDPWM
.|.||| .|| ||...|  |.   .| |||||.|| ||   ||||  .|.. ||.   .  |     .||.|  || . |    ..| ||  ... .||
MTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQN-LRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase TSSK4.AA TyrKc 25-296 21 1.5e-16 44.66 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-296
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVL--RHKYLINFYQAIETT-------SRVYIILELAQGGDVLEWIQ
 . ||..|.| .|.||.. ..   ..|||| . . .     .  |. ||...|. |  .|. ....| .. .          ..|..|.. .|| .. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RYG--ACAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSS-QPVHSSPSYRQMN-SLSH--LSQTYCGSFAYACPEI
...   | ..|  ..  | | | .|||||...||||   | |....  ||||||| .. . .  |   |.  ||..  . ..  |            || 
KHRPKLCMKDLL-SFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML------PIRWMAPEC

LLGLPYNPFLSDTWSMGVILY-TLVVARLPFDD-----TNLKKLLRETQKE--VTFPAN------LTISQECKNLILQLLRQ-STKRATILDVLRDPWML
.    .. . || || || ..  .     |  .      . . ...  ..      |.|       . ..|  ....|  .    .| |  ..       
INYGKFT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HE

KF
.|
CF