Gene TLK1 (Mouse)
TLK1
Sequence
Protein domains of TLK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | TLK1.AA | TLK | 456-734 | 77 | 5.2e-247 | 826.87 | In-house | 1-285 (285) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-285/285 Sequence Identity: 77% (221 aa) YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKL |.||||||.||||||||||||.|.||.|.|||||||.|..|||.||.|||||||.|||||||.|||||||||..|...|||||||||||||||||||||. YQLLHLLGKGGFSEVYKAFDLHEFRYVACKIHQLNKNWKEEKKANYIKHACREYKIHKELDHCRIVKLYDYFEIDNNSFCTVLEYCEGNDLDFYLKQHKT MSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGK-----EPP |.|||||.|.||||..|.||||||||||||||||.||....|..|||||||||||||||||..| ..||.||||||||||||||||||||| .|| MPEKEARCIIMQIVCCLKYLNEIKPPIIHYDLKPQNIIFHKGNTCGEIKITDFGLSKIMDDEQYRHDHGMELTSQGAGTYWYLPPECFVVGKCEEFENPP KISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYL |||.|||||||||||.|||||.||||||.|||.||..|||||||||||| ||.||.|.|.||||||.||.|||.||.||.|.||. KISCKVDVWSVGVIFYQCLYGQKPFGHNMSQQQILEQNTILKATEVQFPSKPQVSNECKDFIRRCLQYRQEDRWDVQQLWNHPYM |
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Kinase | TLK1.AA | S_TKc | 456-734 | 31 | 2.6e-77 | 264.07 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-231/231 Sequence Identity: 31% (92 aa) YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEG--NDLDFYLKQH | .| ..|.|.|..|||. . .|. |.|| .|..|| .|.|. .|| ||||||.| | .. |.|||.| || |.|.. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKR KL------MSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKE . ..| .||... ||..|| |. . ||| |||| |||| . .|||.||||.... . || ||..|| . GRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL----- PPKISN-KVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLAN-------DPYL . . |.|.||.|.|.. .|.|. || |.....| |.||| |||.|| . |.| . .. . .|.. --GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | TLK1.AA | Pkinase | 456-734 | 30 | 1.3e-64 | 225.82 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-293/293 Sequence Identity: 30% (94 aa) YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGN----DLDFYLK | .. .|.|.|..|||. . ... |||| ..|. ....|. .| .. .| .|.|.|.|| ||.|||.| | . |.||||| || |.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI--IKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS --QHKLM--SEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLV-DGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGK .|. . ||.|..... ||. .| |. . ||| |||| |||.. .|. . .||.||||.| .| .. .||.||..|| TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIR--- EPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQ----SQQDILQENTILKATEVQFPVKPVVS-------------------SEAKAFIRRCLAYRKEDRF . .... |||.||.|.|... | || || .. . | .| . ... |. | .|.| ||..||.. ..| GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP DVHQLANDPYL .|. ..|.. TAEQILQHPWF |
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Kinase | TLK1.AA | Ciliate-E2 | 456-734 | 24 | 2.3e-60 | 205.89 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-365/365 Sequence Identity: 24% (93 aa) YLLLHLLGRGGFSEVYKAFDLYEQR------------------YAAVKIHQLNKSWRDEKKENYH-KHACREYR----------IHKELDHPRIVKLYDY | .. ..|.|.|. |||. . .|. ....|| .. ..... .| .|| . | ..|.|| |.|.|.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FSL-DTDTFCTVLEYCEGNDLDFYLKQHKLMS-----------EKEARSIVMQIVN---------------ALRYLNEIKPPIIHYDLKPGNILLVDGTA | |.... |.|||.|.|| |.|..|. . |||.. | ||.. ||.|| . .. ||| |.|| |||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF----- CGEIKITDFGLSKIMDDDSY----GVDGMDLTSQG----------------------AGTYWYLPPECFVVGK-----EPPKISNKVDVWSVGVIFFQCL |||.||||||. |||.. .. .. . .||. |..|| . .| . . |.|.||.|||....| ---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML YGRKPFGHNQSQQDILQENTILKATEVQFP----------------VKPVVSSEAKAFIRR----CLAYRKEDRFD-VHQLANDPYL .|. || . | ...|| . .| |.| .|.. .| . | |.. |. | |.. FGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | TLK1.AA | CAMK | 461-734 | 20 | 2.7e-58 | 186.13 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 461-734 Range on HMM: 1-425/425 Sequence Identity: 20% (89 aa) LLGRGGFSEVYKAFDLYEQ------------RYAAVKI--------------------HQLNKSWRDEK-KENYHKHACREYRIHKE-------LDHPRI ||||.|..|..... . . |.|| ....| .. ... | ||..|.| |||| | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VKLYDYFSL-----------DTDT--------FCTVL---EYCEGN----DLDFYLKQHKL---------------MSEKEARSIVMQIVNALRYLNEIK .|||... .. .. |. |||.| || |...|. ..|.||| .. ||. |..|. . . IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN PPIIHYDLKPGNILLVDGTAC--------------GEIKITDFGLSKIMDDDSYGVDG-----------------MDLTSQGAGTYWYLP-PECFVV--- |.| |||| ||||.| . |||.|||.....|... . .. . || | . || . --IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH -------GKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDI-------LQENTILKATEVQFP-VKPV---------------VSSE-------- | | .. |.|.||.||| . .| |. || . .... .... | .. .. | .| | CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE AKAFIRRCLAYRKEDRFDVHQLANDPYL .| .||..| . |.|. ..| |.| . CKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | TLK1.AA | ULK | 456-734 | 29 | 2e-57 | 197.12 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-329/329 Sequence Identity: 29% (99 aa) YLLLHLLGRGGFSEVYKAFDLYE----QRYAAVKIHQLNKSWRDEKK---ENYHKHACREYRIHKELD--------HPRIVKLYDYFSLDTD-TFCTVLE | | | || | | |||... . . |.|. ...| .... . . ..| .| |.|. || ||||||.| ... . ..| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YCEGNDLDFYLKQHKL----------MSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC---------GEIKITDFGLSKIMDDDSYG ||.| ||. |.|..| ||.||... .||.|....|.. . ||| |.|| |||. .|.. | .||.|||..| .|.|. YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHN--IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME VDGMDLTS-QGA---GTYWYLPPECFVVG--KEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDI------LQENTILKA-----TEVQFPVK--- . | .. . || | |. . ..|. . |.|.||.|.||...|||. || . .... | .|. . . ||| . QQMMMTCVNE-KRLCGTPLYMAPQILQGQGEQKPYYDY-KCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGND PVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYL |..|.| | .|||.| | .||.. ..| | | . PQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | TLK1.AA | Ciliate-E2-Unclassified | 456-734 | 25 | 1.4e-52 | 180.72 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-352/352 Sequence Identity: 25% (90 aa) YLLLHLLGRGGFSEVYKAFDLYEQRYA-----AVKIHQLN-KSWRDE-------KKENYHKHACREY---RIHKE--LDHPRIVKLYDYFSL-DTDTFCT | ... .|.|||..|||. . .. .. . ||.. . |. . . | .| .|. .| .. |.|| ........ |..... YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI VLEYCEGNDLDFYLKQ------------HKLMS-----EKEAR-----SIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIM |.|||||.|| .|.|. |.... |..|. . ||...| || . . |||.|.|| |||. .. ..|||.|||.|| VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY DDDSYGVDGM----------DLTSQGAGTYWYL----PPECFVV-GKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQ------------DILQEN ..... . ..... .||. |. .||.. . . .| |.|.||.|||....|.|. ||. |.. | ...| QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY TILKATEVQFPVKP------VVSSEAKAFIR----RCLAYRKEDRFDVHQLANDPYL . |. ..||| | .| ||| ||. ..| .. . | . |. | |.. QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | TLK1.AA | CAMKL | 456-734 | 28 | 4.8e-45 | 141.6 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-297/297 Sequence Identity: 28% (89 aa) YLLLHLLGRGGFSEVYKAFD-LYEQRYAAVKIHQLNKSWRDEKKEN-------YHKHAC--REYRIHKELD---HPRIVKLYDYF-SLDT----DTFCTV | .. ||.|.|..| | . .. .. |.|| .| | |..... . . ||..|.| |. || |.|||. . .. . .. | YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV LEYCEGND--LDFYLKQH----KLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLV-DGTACGEIKITDFGLSKIMDD--DSYGVDGMDLTS .|||.| . | |...| . |.|.||| . ||| |. |. . . |.| |.|| |||| .| |||.|||.| .... . .| .. . MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG--IVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPG----QKLK QGAGTYWYLPPECFVVGK-EPPKISNKVDVWSVGVIFFQCLYGRKPFG--HNQ--SQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRF |.. | .|| .. . . | . |||.|| ||| . ..|. || ... . .| . . . . ..|. . || ... .||. | |.|. TFCGSPPYMAPE--IFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP DVHQLANDPYL .||. |.| . TIHQIMNHPWM |
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Kinase | TLK1.AA | TKL | 462-722 | 19 | 2.9e-41 | 143.39 | In-house | 1-354 (364) | Show / Hide |
Range on Protein: 462-722 Range on HMM: 1-354/364 Sequence Identity: 19% (71 aa) LGRGGFSEVYKAFDLYE---------QRYAAVKIHQLNKSWRDEKKEN-------------------YHKHACREYRIHKELDHPRIVKLYDYFSLDTDT .|.|||.||||. . . | |... | . .... .. . .. .| .... |.|| ||... | ... IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG ------------FCTVLEYCEGND-LDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIK------PPIIHYDLKPGNILLV-DGT----------ACGEI .| | |||.| . |.... .....| .. || . ||||| |||. |||. ..| | . . CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC KITDFGLSKIMDDDSYGVDGMD-------------LTSQGAGTYWYLPPECFVVGKEPP------------KISNKVDVWSVGVIFFQCLYGRKPFG-HN ||.|||||. |. .. |.| |. ||. ...||.. . . . | |.||.| |.... .| ...|. .. KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP QSQQD------ILQENTILKATEVQFP----------VKPVVSSEAKAFIRRCLAYRKEDR .... . .. ..| | | . . | . .| .. |.| YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKR |
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Kinase | TLK1.AA | STE | 456-734 | 20 | 2.3e-39 | 136.7 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 456-734 Range on HMM: 1-359/359 Sequence Identity: 20% (75 aa) YLLLHLLGRGGFSEVYKAFDLY---------------EQRYAAVKIHQLNK---------SWRDE---KKENYHKHACREYRIHKELD--HPRIVKLYDY . .. .|.|.| .|||| . ... |.|. |.. . . | | .. .. .| .|.|... || ||| |.. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC FSLD------TDTFCTVLEYCEGNDLDFYLKQH--------------KLMSEKEARSIVMQIVNA-LRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKI . . |. . ..||..| || .|. . ..|.. . |. ||. . | || . . ||| |.||.|||| .|. YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL--------VKL TDFGLSKIMDDDSYGV----------DGMDLTSQGAGTYWYLPPECFVVGKEP--PKISNKVDVWSVGVIFFQCLYGRKPF---GHNQSQQDILQEN--- .|||......|.. . .. . .|| . || .... .. . |.|.||.| . |. |. . . |.... CDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQ ------TILKATEVQFPV-----------------KPVVSSEAKAFIRRCLAYRKEDRFDVHQLAN--DPYL |.. . ..| . .|.| | ||..|| . ..| ...|| . | . QQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | TLK1.AA | ULK | 456-618 | 32 | 1.8e-34 | 119.78 | In-house | 1-192 (324) | Show / Hide |
Range on Protein: 456-618 Range on HMM: 1-192/324 Sequence Identity: 32% (64 aa) YLLLHLLGRGGFS-EVYKAFDLYE---QRYAAVKIHQLNKSWRDEKKENY----HKHACREYRIHKELD---HPR--IVKLYDYFSLDTD-TFCTVLEYC | | | || | | |||... . | |.|. ...| .. |.|.. . ..| .| |.|. || ||||||.| ... .. ..||| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKM-NKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC EGNDLDFYLKQHKL---------MSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC---------GEIKITDFGLSKIMDDDS .| ||. |.|..| ||.||... .||.|....|.. . ||| |.|| |||. .|.. | .||.|||..|. |... NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHN--IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNN |
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Kinase | TLK1.AA | PLK-Unclassified | 456-611 | 36 | 9.4e-31 | 108.49 | In-house | 1-153 (264) | Show / Hide |
Range on Protein: 456-611 Range on HMM: 1-153/264 Sequence Identity: 36% (60 aa) YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQH-- | .|.|| |||. .|.. .. . |.|| || .|. . | .||| |.|. ||| .. | | . .||||.. .| |.| . YHRGHFLGKGGFAKCYQVKNIETKKIYAAKI--IPKSSL--TKNRARQKLISEIKIHKSLHHKNIVKFEHCFE-DHENVYILLEYCPNGTLMEYIKRRNF -----KLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLS | ..| |......|||.|| || . ||| |||.|||.| | |.|| ||||. QLFEKKRLTEYEVKCYTYQIVQALKYLHQNR--IIHRDLKLGNIFLNDNM---EVKICDFGLA |
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Kinase | TLK1.AA | ULK | 654-734 | 32 | 5.6e-23 | 78.41 | In-house | 232-324 (324) | Show / Hide |
Range on Protein: 654-734 Range on HMM: 232-324/324 Sequence Identity: 32% (30 aa) KVDVWSVGVIFFQCLYGRKPFGHN-QSQQ----DILQE----NTILKATEVQFPVKP---VVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYL |.|.||.|.||...|||. || . ..|. . .. .. | . .||| .| ..|.| | .|||.| | .||.. ... | | . KCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | TLK1.AA | TyrKc | 456-732 | 25 | 2.7e-13 | -7.84 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 456-732 Range on HMM: 1-280/280 Sequence Identity: 25% (77 aa) YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKEL--DHPRIVKLYDYFSLDT-------DTFCTVLEYCEGNDL |.. ||.| | ||||. . ||| . .. .. .|| || ..| .|| ||.|| .. . . |.||... || ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDL DFYLKQHKL-MSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDD-SYGVDGMDLTS----QGA--GTYWYLP . ||. |. . |. |. || . .|| . ..|| || |.|. .. .||.|||||. .|| . |. . .. .| . .. KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA PECFVVGKEPPKISNKVDVWSVGVIFF-QCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVV---------SSEAKAFIRRCLAYRKEDRFDVHQL |||. | | . | |||| || . . || .| | .. . | . . . .| ..| ...| .. ||| .. PECINYG----KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI ANDP . HECF |
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Kinase | TLK1.AA | Pkinase_Tyr | 507-619 | 32 | 3.3e-09 | 31.81 | Pfam | 52-167 (270) | Show / Hide |
Range on Protein: 507-619 Range on HMM: 52-167/270 Sequence Identity: 32% (39 aa) REYRIHKEL-DHPRIVKLYDYFSLDTDT--FCTVLEYCEGNDLDFYLKQH----KLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTA || .| |.| .|| ||.|| . . . . |.||... ||. ||..| . . |. .. .|| ... || ... .|| || |.|. . REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTE--- CGEIKITDFGLSKIM-DDDSY . .||.||||.. . .|| | NNVVKICDFGLARDIYNDDYY |
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Kinase | TLK1.AA | PLK-Unclassified | 654-734 | 28 | 4.2e-07 | 22.8 | In-house | 188-264 (264) | Show / Hide |
Range on Protein: 654-734 Range on HMM: 188-264/264 Sequence Identity: 28% (23 aa) KVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYL .||.|| |.| | |. || .|. | .|. . || . .|..||..|.. | . |. |. ..|.. EVDCWSFGCILYTLLIGKPPF----ETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY |
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Kinase | TLK1.AA | Pkinase_Tyr | 456-473 | 44 | 5.485289 | 0.58 | Pfam | 1-18 (270) | Show / Hide |
Range on Protein: 456-473 Range on HMM: 1-18/270 Sequence Identity: 44% (8 aa) YLLLHLLGRGGFSEVYKA ... ||.| | ||||. ITFGKKLGEGAFGEVYKG |