Gene TIF1g (Mouse)
TIF1g
Sequence
Protein domains of TIF1g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| RING | TIF1g.AA | RING | 139-198 | 21 | 1.2e-10 | 42.57 | SMART | 1-23 (23) | Show / Hide |
Range on Protein: 139-198 Range on HMM: 1-23/23 Sequence Identity: 21% (13 aa) CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDVQQVGVIRCPVC |..| . |..||| | || |. ||.| CPICLE---------PVVLPCGH-FCY-CI--------------------------CPIC |
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| Zf-C3HC4 | TIF1g.AA | zf-C3HC4 | 139-168 | 25 | 0.001011 | 11.81 | Pfam | 1-33 (48) | Show / Hide |
Range on Protein: 139-168 Range on HMM: 1-33/48 Sequence Identity: 25% (9 aa) CAVCQQSLQSRREAEPKLLPCLHS-----FCLRCL |..|.. . . | ..||.|. || |. CWICHCEWKDPNN--PLIHPCGHRGSLKWFCHSCI |
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| PHD | TIF1g.AA | PHD | 138-199 | 18 | 0.039503 | 3.33 | SMART | 1-39 (39) | Show / Hide |
Range on Protein: 138-199 Range on HMM: 1-39/39 Sequence Identity: 18% (13 aa) TCAVCQQSLQSRREAEPKLLPCL-------HSFCLRCLPEPERQLSVPIPGGSNGDVQQVGVIRCPVCR .| ||.. .. | | ||. .| . | .|| || YC-VCGK---------G-MIQCDPGCDRWYHQ-CLGPPLE-----------------PPDG-WYCPRCR |
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| BBOX | TIF1g.AA | BBOX | 285-326 | 31 | 5.3e-13 | 50.44 | SMART | 1-51 (51) | Show / Hide |
Range on Protein: 285-326 Range on HMM: 1-51/51 Sequence Identity: 31% (16 aa) QRPVFCPVHK-QEQLKLFC-ETCDRLTCRDCQLL-EH------KEHRYQFL .||. |..|. | ...|| |.|. . |.|| . || . |....| HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL |
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| BBOX | TIF1g.AA | BBOX | 226-273 | 25 | 4.7e-12 | 47.29 | SMART | 1-51 (51) | Show / Hide |
Range on Protein: 226-273 Range on HMM: 1-51/51 Sequence Identity: 25% (13 aa) KSEQVCTSCEDNASAVGFC-VECGEWLCKTCIEA--HQRVKFTKDHLIRKK .....|....... |. || ..|...||..| |. ||..|....| .. HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL |
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| Zf-B_box | TIF1g.AA | zf-B_box | 286-326 | 28 | 2e-09 | 42.01 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 286-326 Range on HMM: 1-45/45 Sequence Identity: 28% (13 aa) RPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKE-----HRYQFL .. || |..| |...|..|... |.|| . .|| |... . QM-YCPEHPEEPLEYYCQDCQQCICEDCAVHGHKGNGFKKHTVVPI |
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| Zf-B_box | TIF1g.AA | zf-B_box | 227-273 | 16 | 8.9e-07 | 31.48 | Pfam | 1-45 (45) | Show / Hide |
Range on Protein: 227-273 Range on HMM: 1-45/45 Sequence Identity: 16% (8 aa) SEQVCTSCEDNASAVGFCVECGEWLCKTCIEA-HQRVKFTKDHLIRKK .. .| .... . .| .|.. .| |... |.. . .|.| ... QM-YCPEHPEEP-LEYYCQDCQQCICEDCAVHGHKGNG-FKKHTVVPI |
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| RING | TIF1g.AA | RING | 231-293 | 14 | 0.007892 | 6.68 | SMART | 1-23 (23) | Show / Hide |
Range on Protein: 231-293 Range on HMM: 1-23/23 Sequence Identity: 14% (9 aa) CTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGTSGQRPVFCPVH |. | . .. .|| |. || ||. CPICLE-----PVVLPCGH-FCY-CI---------------------------------CPIC |
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| PHD | TIF1g.AA | PHD | 248-258 | 45 | 0.203927 | 6.02 | Pfam | 44-54 (54) | Show / Hide |
Range on Protein: 248-258 Range on HMM: 44-54/54 Sequence Identity: 45% (5 aa) GEWLCKTCIEA |||.|. |... GEWYCPRCKCC |
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| BBC | TIF1g.AA | BBC | 333-459 | 32 | 4.7e-47 | 163.57 | SMART | 1-132 (132) | Show / Hide |
Range on Protein: 333-459 Range on HMM: 1-132/132 Sequence Identity: 32% (43 aa) QKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVN-----ETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVM .. ..| .|.|| .|... ..|. |.||.|..|. |. ..|||.|......|.|..|...| .|..|.......|..| ||. ..|....|..|.. HREKLEQHLTKLRKKHWECEDAMKQIQNIIQQVQPGHVDENHEDVEQCIRAHFDDLMNWLNRRKKMMLMDLDEQCENKQKWLMQQMQTMTQKQEQLEHCC NFTNWAIASGSSTALLYSKRLITFQLRHILKA .|..||. .|..|..|.||.||.||..| .|. QFCQWALNMGDCTEFLQSKKLIIFQCCHLHKQ |
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| PHD | TIF1g.AA | PHD | 902-947 | 38 | 1.2e-16 | 53.58 | Pfam | 1-54 (54) | Show / Hide |
Range on Protein: 902-947 Range on HMM: 1-54/54 Sequence Identity: 38% (21 aa) WCAVCQN-----GGDLLCCE-KCPKVFHLTCHVPTLL--SFPSGDWICTFCRDI .|.||| .||..||. .||. ||. || |.| |.|.|.|. |. YCCVCQKCDWDDDGDMICCDNGCPRWFHQYCHGPPLEPEEIPEGEWYCPRCKCC |
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| PHD | TIF1g.AA | PHD | 902-945 | 35 | 1.7e-13 | 52.07 | SMART | 1-39 (39) | Show / Hide |
Range on Protein: 902-945 Range on HMM: 1-39/39 Sequence Identity: 35% (16 aa) WCAVCQNGGDLLCCE-KCPKVFHLTCHVPTLLSFPSGDWICTFCR .| ||. | ...|. .|.. .|. |. |.|. |.| |.| || YC-VCGK-G-MIQCDPGCDRWYHQ-CLGPPLE-PPDG-WYCPRCR |
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| Zf-C3HC4 | TIF1g.AA | zf-C3HC4 | 920-944 | 28 | 3.63551 | 1.53 | Pfam | 26-48 (48) | Show / Hide |
Range on Protein: 920-944 Range on HMM: 26-48/48 Sequence Identity: 28% (7 aa) KVFHLTCHVPTLLSFPSGDWICTFC |.|. .| . . . || . | .| KWFCHSCIKRWWNH--SGNTQCPIC |
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| BROMO | TIF1g.AA | BROMO | 972-1095 | 33 | 1.5e-32 | 115.38 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 972-1095
Range on HMM: 1-118/118
Sequence Identity: 33% (46 aa)
SPVDQRKCERLLLYLYCHELSI------------EFQEPVPVS---IPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMK
.| |.||..|| ..||. . |..||... .|.||.|||.||||.|.||||.. . | ...||.|..|.|.|| .||
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQY---QSMEEFVDDFMLMFNNCMTYNE---
VVQVYADTQEINLKGDSEVAKAGKAVALYFEDKLSEIYS
|||| |..| .||.|. |..
--------------PDSEVYKMAKKLQKFFEEKWREFPP
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| Bromodomain | TIF1g.AA | Bromodomain | 979-1064 | 30 | 1.4e-28 | 95.61 | Pfam | 1-89 (89) | Show / Hide |
Range on Protein: 979-1064 Range on HMM: 1-89/89 Sequence Identity: 30% (28 aa) CERLLL--YLYCHELSIEFQEPV---PVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQ-IPDDFVADVRLIFKNCERFNEMMKVVQVYADT |.... |.. |... |..|| ....|.||.|||.||||||...|| ....|. ...| .|..|...||...|. .. ..|.. CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKL---KNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK |
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