Gene SgK493 (Mouse)

SgK493

Species: Mouse
Alias: SgK493, X83346
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: SgK493

Sequence

Name Sequence Type Origin Length Description Download
SgK493.AA Protein Sugen 492 None Fasta, JSON
SgK493.NA RNA Sugen 2378 None Fasta, JSON
SgK493.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 228 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of SgK493.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SgK493.AA SgK493 141-368 58 2.7e-206 597.82 In-house 1-234 (234) Show / Hide 
Range on Protein: 141-368
Range on HMM: 1-234/234
Sequence Identity: 58% (137 aa)

AQYVGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVR--EFGARRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEGIPDT----LTTITE
.||.|.|.||.|||.|..||..||.|.||...||...|..  .......|||.|..||.|||..|..||||...|||||||.|..|.||.    .||..|
GQYIGQGHTKEVYRGRYMGGRKVAIKMVDMQVHDVKMCLNRRDYHIKEDCYRYAMYKLMKEMMYLRQLRHPHIVQLYGYCYRDDNGSPDIRDQGITTVVE

LGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVNGELKVTDLDDARVEETPCTSSADCTLEFPARNFSLPCSAQGWCEGM
||.||.|.||.||.||.|||.|..||||||||.|||.|||...|||..|||||.|.||||||||....|..|..|.||......|||...|.|..|||||
LGKPVHMHQLVQTMWEQRFRYCMDLGRLLHHLEHSPMGSVNISDFRDNQFVLVDGRLKVTDLDDMSTQEQDCDRSMDCIINGKDRNFAVKCCANMWCEGM

NEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIV
|.|||||.|||||||.||.|..||||||||||||
NAKRNLYHAYRFFFTPLLQHDVPPSLRPLLDSIV
Kinase SgK493.AA IRAK 197-223 40 5e-07 21.14 In-house 51-77 (317) Show / Hide 
Range on Protein: 197-223
Range on HMM: 51-77/317
Sequence Identity: 40% (11 aa)

LKEMVLLERLRHPNVLQLYGYCYQDSE
..|. .. |.||||.. |||||.. ..
YNELKVCCRCRHPNIVPLYGYCTERQC
Kinase SgK493.AA TESK 194-221 39 5.1e-07 17.73 In-house 38-65 (292) Show / Hide 
Range on Protein: 194-221
Range on HMM: 38-65/292
Sequence Identity: 39% (11 aa)

HKLLKEMVLLERLRHPNVLQLYGYCYQD
|..|.|. |. .|.|||.|   | | ..
HNMLREVQLMNKLQHPNILRFMGVCVHQ
Kinase SgK493.AA TK 29-221 5 8e-06 14.65 In-house 82-115 (486) Show / Hide 
Range on Protein: 29-221
Range on HMM: 82-115/486
Sequence Identity: 5% (11 aa)

GSEPPRPGQSPGSSAAPGPGRRGGRGELARQIRERYEEVQRYSRGGPGPGAGRPERRRLMDLAPGGPGLQRPRPPRVRSPPDGAPGWPPAPGPGSPGPGP
|                                                                                                   
G---------------------------------------------------------------------------------------------------

RLGCAALRNVSGAQYVGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGARRGCYRLAAHKLLKEMVLLERLR-----HPNVLQLYGYCYQD
                                                              .   . |.|.  .. ..     |||...|||.| |.
--------------------------------------------------------------E---DFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQG
Kinase SgK493.AA TKL 195-235 28 8e-06 17.01 In-house 71-119 (364) Show / Hide 
Range on Protein: 195-235
Range on HMM: 71-119/364
Sequence Identity: 28% (14 aa)

KLLKEMVLLERLRHPNVLQLYGYCYQDSE--------GIPDTLTTITEL
.. .|.... ||||||..|..||| . .         | .  |  ..|.
FEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEY
Kinase SgK493.AA LISK 194-223 38 9e-06 14.59 In-house 41-71 (296) Show / Hide 
Range on Protein: 194-223
Range on HMM: 41-71/296
Sequence Identity: 38% (12 aa)

HKLLKEMVLLERLRHPNVLQLYGYCYQ-DSE
...|.|. .. .|||||..| .| ||. |..
KFMLREVQMMKNLRHPNIVQFMGVCYHNDGQ
Kinase SgK493.AA Dicty4 196-218 34 1.9e-05 14.36 In-house 45-67 (277) Show / Hide 
Range on Protein: 196-218
Range on HMM: 45-67/277
Sequence Identity: 34% (8 aa)

LLKEMVLLERLRHPNVLQLYGYC
..||  ..  .||||.....|.|
FRKEVHIMCKIRHPNICLFMGAC
Kinase SgK493.AA RTKL 197-216 50 2.6e-05 9.5 In-house 47-66 (259) Show / Hide 
Range on Protein: 197-216
Range on HMM: 47-66/259
Sequence Identity: 50% (10 aa)

LKEMVLLERLRHPNVLQLYG
|.| |||  | ||.. |..|
LYEAVLLHQLHHPHIIQMHG
Kinase SgK493.AA Ret 194-221 53 3.5e-05 13.59 In-house 48-75 (293) Show / Hide 
Range on Protein: 194-221
Range on HMM: 48-75/293
Sequence Identity: 53% (15 aa)

HKLLKEMVLLERLRHPNVLQLYGYCYQD
| || |. ||  . ||.|  ||| | ||
HDLLSEFQLLKQVNHPHVIKLYGACIQD
Kinase SgK493.AA Aur 205-217 61 4.3e-05 8.83 In-house 55-67 (257) Show / Hide 
Range on Protein: 205-217
Range on HMM: 55-67/257
Sequence Identity: 61% (8 aa)

RLRHPNVLQLYGY
.|.|||.|..|||
HLNHPNILKMYGY
Kinase SgK493.AA S_TKc 138-393 11 0.000508 -117.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 138-393
Range on HMM: 1-231/231
Sequence Identity: 11% (35 aa)

VSGAQYVGSGYTKAVYRVRLPG-GAAVALKAVDFSGHDLGSCVREFGARRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEGIPDTLTTITELG
    . .|.|    ||..|  . |  ||.| ..                         ....|. .|.. .|||. .||....       | |  ..|. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYC

AP--VEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTL-------LDFRPRQFVLVNGELKVTDLDDARVEET--------------PCTS-SAD-
     .. ....     . |  ..  .  . ..   ..   .        |  |    | . ..|..|   ||.  |              . .  ..| 
DGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-TTFCGTPWYMAPEVLGYGKCKCDW

----------CTLEFPARNFSLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLA-QLETALHLFR
          .. . | .                   ...  ..           .|... ... . .   |  ... | |. ... ..| . 
WSCGCILYEMLCGYPPFP-------------------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF