Gene SGK3 (Mouse)
SGK3
Sequence
Protein domains of SGK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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PX | SGK3.AA | PX | 11-120 | 30 | 3.7e-28 | 99.07 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 11-120 Range on HMM: 1-120/120 Sequence Identity: 30% (37 aa) ESCPSVSIPSSDEH---REKKKRFTVYKVLVSVG---RSEWFVFRRYAEFDKLYNSLKKQFPAMAL-KIPAKRIFGD--NFDPDFIKQRRAGLNEFIQNL .. .|.. . | .|.....||.. .. . ..||.|.||| .| .|. ||..||.. . ..|.|..|| |||..||..||..|....|.. DHFLQVHVVDPETHKHYGDKMHYYYVYEIHMNTNPFQKKEWHVWRRYSDFHWLHKQLKRHFPMCIIPPLPPKHWFGRYNNFDEEFIEKRRQMLEQYLQRV VRYPELYN-HPDVRAFLQMD .. ||| | .... ||. | CQHPELCNHCEVFHDFLHPD |
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PX | SGK3.AA | PX | 13-120 | 25 | 1.6e-21 | 78.77 | SMART | 1-142 (142) | Show / Hide |
Range on Protein: 13-120 Range on HMM: 1-142/142 Sequence Identity: 25% (36 aa) CPSVSIPSSDEH------REKKKRFTVYKVLVSVG--RSEWFVFRRYAEFDKLYNSLKKQFP-----AMALKIPAKRIFGD-----------------NF .. | .... ..| ...||.. .. . ...| |.||| .| .|.. ||..|| . ..|.| .|. || DHIFIITVVEFFTHGKHYHDGKHYYYVYEIHTKTNNHVKMWTVYRRYSDFHWLHHQLKRHFPQEKRMCIIPPLPPKHWFVRYRYWMEHMSMMWWYSFNNF DPDFIKQRRAGLNEFIQNLVRYPELYNH----PDVRAFLQMD |.||| .|| ||....| |.. ||. || ..|. |.. . DEDFIEKRRRGLERYLQRLCHHPEWINHYMVCEVVYEFFESS |
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Kinase | SGK3.AA | SGK | 162-419 | 64 | 9.40000000001e-226 | 704.86 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-283/283 Sequence Identity: 64% (183 aa) FDFLKVIGKGSFGKVLLAKRKLD------------------GKFYAVKVLQKKIVL-------NRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKL |||||||||||||||...|.| | .||||.|||||. .. ..||||||||||||.|||.||||.|.|||.|||..|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ |||.|.|||||.|.|||||..|||.|||||||||..||.||||..|.||||||||||||..||..|||||||||||. .|||.|||||||||||||.||| YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ PYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFF |.|.||||||||.|||||.|||||||.|....|||||...||...|..| .||.....||.|....|||.|.||.||.||||| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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Kinase | SGK3.AA | AGC | 162-419 | 36 | 8.10000000001e-189 | 493.59 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-395/395 Sequence Identity: 36% (146 aa) FDFLKVIGKGSFGKVLLAKRK------LDGKFYAVKVLQK--KIVLNRK-EQKHIMAE------------RNVLLKNVK---------HPFLVG-LHYSF |.||||||||||||| |...| ||.||.|||.| |||...| ...|.|.| ||.| | . |||.| ||||| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTTEK--LYFVLD----FVN-----GG-ELFFHLQ---RERSFPEPRARFYAAE-------IASALGYLHS-IKIVYRD-LKPENILLDSMGHVVLTDFG |. .. ||||.. .|| || |||.||| .|..|.|.|||||||| |..|| |||| .|..|| |||||||||. ||. ||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCKEGIAIS--------------------------------------------------DTTTTFCG--TPEYLAPEVIRKQPYDNTVDWWC--LGAVLY |||||. |.|.|||| ||||.|||.. |. ..|||. ||...| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLYGLPPFYCR----------DVAEMYDNIL------HKPLNLR----------PGVSLTAWSILEELLEKNRQNRLGAKED------FLEIQNHPFF |||.|.|||| . .||...|. .... . . .| |..... ||.|.. .|||.... . ||.|||.| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | SGK3.AA | Akt | 162-419 | 53 | 1.8e-161 | 520.0 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-264/264 Sequence Identity: 53% (141 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFY-AVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPE ||||||.||||||||.|.| | ..|.| | |||.|. ..... .|...|||. |....|||.|.||||||| .|||||.|..||||||.||||.| |.| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNI-LQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE PRARFYAAEIASALGYLHSIKIVYRD-LKPENILLDSMGHVVLTDFGLCKEG-IAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWC-LGAVLYEMLYG .|||||.||| .|...||| |.||| |||||||.|. ||. |||||||||. | |.|.||||||||||||.. .. .. .|||| ||.|.|||..| DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG LPPFYCRDVAEMYDNILHKPLNLR--PGVSLTAWSILEELLEKNRQNRLG-AKEDFLEIQNHPFF .|||| .|. .|...|. .|.. . .| . .... ||.|.. .||| ...| ||..||.| RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | SGK3.AA | PKC | 162-419 | 47 | 6.1e-127 | 413.57 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-262/262 Sequence Identity: 47% (125 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEP |.||||.||||||||.||.|| ..||.||| | ... |.|. || |||||..|| .||| ..|.||. .|||| | || |. | |.|. FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE RARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPF .||||||||..|| .||. |.||||| .|.|||. ||. ..|||.|||.. |||.||||||.|.|||... |.| |||| .| .|||. | .|| HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF YCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKED----FLEIQNHPFF | |. ..|.|. | | ||.. ...|| ..|||.... . .|. |||| HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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Kinase | SGK3.AA | AktR | 162-419 | 44 | 2.7e-124 | 419.22 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-268/268 Sequence Identity: 44% (119 aa) FDFLKVIGKGSFGKVLLAKRK-LDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPE |...|..||| |||| |...| ..|.|| |.. || .|. ..|. |||.. . ..|||.| |||.||| |||.|..... |||||.||.... | | FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE PRARFYAAEIASALGYLHSI-KIVYRDLKPENILLDSMGHVVLTDFGLCK-EGIA-ISDTTTTFCGTPEYLAPEVIRK-QPYDNTVDWWCLGAVLYEMLY .||||.|.| || |||. .|.||||||||||||. ||| .||||| | ... ......|||||||.|||.|.| .... .||||..|...|||.. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GLPPFYCRDVAEMYDNILHKP-LNLRPG--VSLTAWSILE-ELLEKNRQNRLG-AKEDFLEIQNHPFF |.|||| . .|...|. |. . . .| .. .... || || ..||| ..... || .||.| GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | SGK3.AA | RSK | 165-419 | 42 | 2.2e-117 | 396.28 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 165-419 Range on HMM: 1-278/278 Sequence Identity: 42% (119 aa) LKVIGKGSFGKVLLAKRK---LDGKFYAVKVLQK-KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERS--- ||| |.|..||| | ... |. ||.|||.| ||| . | ..| |.|||.|. .|||.| |||.||| .||| ......||||| |||.|.. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDS---MGHVVLTDFGLCKEGIAI-SDTTTTFCGTPEYLAPEVIR---KQP-YDNTVDWWCLGA | | .|.||.|||..|. .||. .|..|||||||||.|. ||..|||||.||.. . . | |||.| ||.|||... .| .| .||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV VLYEMLYGLPPFYC---RDVAEMYDNILHKP--LNLR--PGVSLTAWSILEELLEKNRQNRLGA-KEDFLEIQNHPFF ..|||| | |||. . .| ..|... |.. . .| .| ... .|... ..|||. ..| ||..||.| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | SGK3.AA | PKA | 162-419 | 41 | 7e-111 | 374.67 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-263/263 Sequence Identity: 41% (111 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVG-LHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPE |......|.||||.| |.. | .|..|| |.| | . .| . |.. |.|. |.|.||||.| . ..||. .||.|...|.|||.| .|.....|.. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNI-LQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN PRARFYAA-EIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ-PYDNTVDWWCLGAVLYEMLYGL | |.|||| .| .|| |||| |.||||||||||.|. ||. .|||| |. . | | | ||||||||||.| .. ||||.|| . |||| | PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK---VDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY PPFYCR--DVAEMYDNILHKPLNLRPGVSLTA---WSILEELLEKNRQNRLGAKE-DFLEIQNHPFF |||| |....|. |. .. . .. | . .. ||.... |.| .. . | ||..| PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | SGK3.AA | p70 | 162-419 | 42 | 1.6e-109 | 370.17 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-299/299 Sequence Identity: 42% (128 aa) FDFLKVIGKGSFGKVLLAKRKL---DGKFYAVKVLQK-KIVLNRKEQKHIM-------------------------AERNVLLKNVKHPFLVGLHYSFQT | |||.||| .|||.. . || || |||.| ||| | | | ||||. | |||||.. |||.||| FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNI-LEEVKHPFICDLHYAFQT TEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDT----------TTTFC .||| .|.. ||||| || |. ..| |.||..|| ||..||. |.||||||||..|.. ||||||||||||| | . | ||| NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC GTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP--LNLRPGVSLTAWSILEELLEKNRQNRLG-AKEDFLEIQNHPFF ||.|| |||.... .. |||| ||. .| || | ||| .. | || |.| | . . .. || .. . |.| || .|| |||| GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | SGK3.AA | S_TKc | 162-419 | 37 | 6.6e-108 | 365.7 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-231/231 Sequence Identity: 37% (100 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNG--GELFFHLQRERS-- ...|..||||.|||| ... | .|. .|.|.. .||. |...| | .||..| |...||. ..||.|.....| |.|| .... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----FPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN-TVDWWCLGAVLY ||| .||||...|..|| |.|| .|..|||||||||||. |. ..||||... |||||||.|.||||. .|. .||| .| .|| LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY EMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFL---EIQNHPFF |||.| |||. ....|...|. | |..... .|.|. ..|..| | . .| .||.| EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | SGK3.AA | Eta | 162-419 | 48 | 3e-107 | 362.62 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-261/261 Sequence Identity: 48% (126 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEP |.|.||.||||||||.||.|| . ||.|||.| ... . |.|. .| ||||| || .||| ..|.||...||||.| |..|| | | || FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP RARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPF ||||||||. .|| .|| ..||||| .||||| || | |||.||||| |||||||||.|.|||... . | .|||| .| ..|||. | ||| RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF YCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKE---DFLEIQNHPFF .... ||| .. | ||| . || . |||. . . .|..|||| EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF |
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Kinase | SGK3.AA | RSK | 162-419 | 36 | 1.2e-103 | 350.61 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-271/271 Sequence Identity: 36% (101 aa) FDFLKVIGKGSFGKVLLAKRK---LDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSF ......||.|||.|| . |.. .. ||.|...|. . .. .||. .| .. ||| | |||.||. .|.| ..|| ||.|| .|.....| YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERI-ILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF PEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSM----GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEM .| ..||.||||.|. |||| .||.|||||||||.|.. ||. ..|||. |. .. . |||.| .|.||||...| .| .||| .|...||| SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM LYGLPPFYCRDVAEMYDNILHKPLNL-------RPGVSLTAWSILEELLEKNRQNRLGA-KEDFLEIQNHPFF | | .||. .. .. ..|. .| . .| .| . | .|. . .||||| .. .| .||.| LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | SGK3.AA | Pkinase | 162-419 | 32 | 2.8e-86 | 297.76 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-293/293 Sequence Identity: 32% (98 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIM-AERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG----ELFFHLQ--R . ....||.||||.| ....| .|| .|||.. |. |.| |. .| .... .||. | |...|.. ..|.|.....|| .|| ... | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR ERSF--PEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHV----VLTDFGLCKEG-IAISDTTTTFCGTPEYLAPEVIR-KQPYDNTVDWWC ...| .| ..||. .|...| |.|| .|..|||||||||.|. ||. ..||||.| . . .|||||||.|.|||||| |.|. ||.| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS LGAVLYEMLYGLPPFYCR------DVAEMYDNILHKPLNLRPGVS---------------------LTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFF .| .||||| | |||. . | .|...|...|| . .. .... .|.|. . |.. . .| .||.| CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF |
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Kinase | SGK3.AA | S_TK_X | 420-489 | 26 | 1.1e-14 | 56.09 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 420-489 Range on HMM: 1-79/79 Sequence Identity: 26% (23 aa) ESLSWTDLVQ--KKIPPPFNPNVA----GPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEA-----------DDAFVGFSYAP .. | .| . |.|.||| |.. .| |..||| |||||. .. .. .... .| | ||.| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM--------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | SGK3.AA | TyrKc | 162-419 | 21 | 8.4e-14 | 0.48 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 162-419 Range on HMM: 1-280/280 Sequence Identity: 21% (62 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKN-VKHPFLVGLHYSFQTT-------EKLYFVLDFVNGGELFFHLQ ..|..| | ||.| ... | |||.|.. .. .| | ... | .|| .| |. . | |. |. .. .| | .|. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RERS-FPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAI-------SDTTTTF--CGTP----EYLAPEVIRKQPYD . | .. . .. ||. |||| ... ||| |.|... ..| .||||.... . ... .| .|||.|.. . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT NTVDWWCLGAVLYEML-YGLPPFYC-----RDVAEMYDNILHKPLNLRPGV---------SLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFF | | | ...|.. || .| . . .|.. .. . .| . .| .. . . .| | || | .| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP----TFSEI--HECF |
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Kinase | SGK3.AA | Pkinase_C | 439-491 | 26 | 1.8e-12 | 47.16 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 439-491 Range on HMM: 1-46/46 Sequence Identity: 26% (14 aa) NVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPS .| .|.|..||| ||.|...... . . . .....|.||.| .|. QVKSPTDTSNFDPEFTDEPPMDTP------PDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | SGK3.AA | Pkinase_Tyr | 162-309 | 24 | 2e-08 | 29.15 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 162-309 Range on HMM: 1-159/270 Sequence Identity: 24% (39 aa) FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKI--VLNRKE--QKHIMAERNVLLKNV-KHPFLVGLHYSFQ-TTEK--LYFVLDFVNGGELFFHLQ |.|..|.|.||.| ... | |.. ..| |.. .. .. |.| .. .|. .|| .| |. | .| |. .. .| | .|. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKI-MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR R----ERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCK . ..... .. ....||... ||.|.... ||| |.|... ..| .||||.. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |