Gene SCYL3 (Mouse)

SCYL3

Species: Mouse
Alias: SCYL3, 1200016D23Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
SCYL3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 221 Kinase domain by global Sugen HMM Fasta, JSON
SCYL3.NA RNA Sugen 2997 None Fasta, JSON
SCYL3.AA Protein Sugen 735 None Fasta, JSON

Protein domain

Protein domains of SCYL3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SCYL3.AA SCY1 18-245 20 4.7e-80 272.27 In-house 1-337 (337) Show / Hide 
Range on Protein: 18-245
Range on HMM: 1-337/337
Sequence Identity: 20% (70 aa)

FTLPSGLAVYPAILQDGKCASVF--------VYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADG--IHLVTERVQPLEVALETLSP----------
 .. .| ..|..  .. ......        ....|......|.||.||.||||..|.......| .   .....|..|||| .|....           
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ

-----------------------AEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGG---------METVCQVPQATPEFLRNIQSVR-
                       .|||.||..|| ||.|||...|..|||.| .|.|| ..|.||.||         |..||......|.......... 
DVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWR

------------DPASIPPEEMSPEFSGLPESHG-----------------HARDAYAFGALVDSLLPIFN----EQVSA-------------------D
            |....||....|...  ...|.                 .|.| . .|.|. ... ...    .. ..                   |
EMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWD

VLSSFLQIL----HSALLNPMPECRPALSTLLSHDFF
 . ..|| .    ...||...|.||| ....|.|..|
HIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
Kinase SCYL3.AA PLK 224-245 40 4e-07 19.36 In-house 237-258 (258) Show / Hide 
Range on Protein: 224-245
Range on HMM: 237-258/258
Sequence Identity: 40% (9 aa)

ALLNPMPECRPALSTLLSHDFF
..||. |. || .. .|.|.||
KMLNWNPDERPTIDQILQHPFF
Kinase SCYL3.AA PLK2 223-245 47 9.2e-07 17.51 In-house 235-257 (257) Show / Hide 
Range on Protein: 223-245
Range on HMM: 235-257/257
Sequence Identity: 47% (11 aa)

SALLNPMPECRPALSTLLSHDFF
...| | || || |  .. ||||
ARMLSPDPEDRPSLDHIIRHDFF
Kinase SCYL3.AA S_TKc 18-245 14 3e-06 -84.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-245
Range on HMM: 1-231/231
Sequence Identity: 14% (38 aa)

FTLPSGLA------VYPAILQDGKCASVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQ----PLEVALET---------LSPA
...   .       || ..  .     ..  |. . ... .  . ||  .|| . ... . .. | ...|.| .      |   ..          ... 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

EVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCQVPQATPEFLRNIQSVRDPASIPPEEMSPEFSGLPESHGH-ARDAYAFGAL
...  .| |..|| ..|.. .  |  .  . ....|  | |..     .|.               .     |. |.||      ..|. . | ...| .
HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

V------DSLLPIFNEQVSADVLSSFLQILH---SALLNPMPECRPALSTLLS-------HDFF
.        . |  ..|.  ...    . .    . .|.  || ||    .|        | .|
LYEMLCGYPPFP--QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SCYL3.AA PLK1 224-245 36 0.000475 8.91 In-house 232-253 (253) Show / Hide 
Range on Protein: 224-245
Range on HMM: 232-253/253
Sequence Identity: 36% (8 aa)

ALLNPMPECRPALSTLLSHDFF
..|.| |. ||. . .|. .||
KMLDPDPTRRPTIEQVLNDEFF
Kinase SCYL3.AA PLK-Unclassified 226-245 35 0.000483 11.38 In-house 245-264 (264) Show / Hide 
Range on Protein: 226-245
Range on HMM: 245-264/264
Sequence Identity: 35% (7 aa)

LNPMPECRPALSTLLSHDFF
||. |. || .. ...|.|.
LNWNPDQRPTIDQIMMHPFY
HEAT SCYL3.AA HEAT 338-368 22 0.083 10.12 Pfam 1-31 (31) Show / Hide 
Range on Protein: 338-368
Range on HMM: 1-31/31
Sequence Identity: 22% (7 aa)

VIPVLLRLFEVHEEHVRMVLLSHIEAYVEHF
..|.||....  ...||.  .. . . .||.
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT SCYL3.AA HEAT 377-407 25 0.004885 14.38 Pfam 1-31 (31) Show / Hide 
Range on Protein: 377-407
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

ILPQVLLGLRDTSNSIVAITLRSLAVLVSLL
||| .| .|.|.. .. . ....|..|.. .
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC