Gene RIOK3 (Mouse)

RIOK3

Species: Mouse
Alias: Sudd, RIOK3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO3

Sequence

Name Sequence Type Origin Length Description Download
RIOK3.AA Protein Sugen 519 None Fasta, JSON
RIOK3.NA RNA Sugen 3661 None Fasta, JSON
RIOK3.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of RIOK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIOK3.AA RIO3 226-479 93 3.8e-191 641.31 In-house 1-254 (254) Show / Hide 
Range on Protein: 226-479
Range on HMM: 1-254/254
Sequence Identity: 93% (238 aa)

HSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKII
||||||||||||||||||||||||||||||||.||||||||||||||.|||||| | |||.|||||||||||||||||||||||||||||||||||||| 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

RMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSNEEMKDAYYQTLHLMQQLYNECTLVHADLSEYNMLWHAGKVWLIDVS
|||||||||||.|||.||||||||||||||||||||||||||||||||||||  ||||.|||||||||.||| |||||||||||||||||||||||||||
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVS

QSVEPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNERELFNAVSGLNISADNEA
|||||||||||||||||||||||||||||| ||| |||||||||||||.|||||
QSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA
Kinase RIOK3.AA RIO 229-478 43 2.7e-164 552.09 In-house 1-276 (276) Show / Hide 
Range on Protein: 229-478
Range on HMM: 1-276/276
Sequence Identity: 43% (120 aa)

AEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMW
.|...||.||..||||||.||.|....||..||||...|..... |||||| | ||||||||...|....||.|.||....|.||.|..|.|.|...|.|
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLS-NEEMKDAYYQTLHLMQQLYNECTLVHADLSEYNMLWHAGKV-------W
|||||.|. |....|.|||.....|.|.|||.||.|||.||||.......  |.|| .|.|....| .||..|.|||.|..|.||.||.||.       .
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

LIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNERELFNAV------------------SGLNISADNE
.||..|.||..|||.|....|||..|..||.|..| |.. |||.|..|                  ..... ..|.
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
RIO RIOK3.AA RIO 222-470 47 3.9e-143 482.74 SMART 1-253 (253) Show / Hide 
Range on Protein: 222-470
Range on HMM: 1-253/253
Sequence Identity: 47% (124 aa)

EKKEHSTAEKAVDPKTRLLMYKMVNSGMLETIT--GCISTGKESVVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKL
.|....|.|...||.||...|||||.|..|.|.  ||||||||..|.||.||       | .  ..|||.|...|...|||....||..|||||......
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGG-------DFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHI

NPRKIIRMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSNEEMK---DAYYQTLHLMQQLYNECTLVHADLSEYNMLWH-
|.||..|.|||||..|| ||..||.|||.......|.|||.|||.|..|||.||.|.. ..||.    .|.|... | ..|.||.||||||||||||.| 
NWRKMVRLWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHD

-----AGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNERELFNAVSG
     ..|||.||.|||||..||. ||||.||..|...||.. ||..   .||.|. . |
LEDENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase RIOK3.AA RIO1 264-464 46 2.4e-119 372.66 Pfam 1-200 (200) Show / Hide 
Range on Protein: 264-464
Range on HMM: 1-200/200
Sequence Identity: 46% (98 aa)

VVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIG
.|.|||.   ||.|.       |||.|...|....||....|...||||..|... |.|...|||||||..|| ||..||.||| ......|.|||.|||
NVYHAYS--MEDGKD-------ECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIG

-HDQVPAPKLKEVK----LSNEEMKDAYYQTLH-LMQQLYNECTLVHADLSEYNMLWHAG-KVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVT
 .| .|||.||.|     || ||..  |.....  |  .|.|| |||.||||||.|.| . |.|.||..|.||. ||| |||| |||||...||.. || 
DKDGWPAPRLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVD

E-ALNEREL
| .. .||.
ERVMDFREI
Kinase RIOK3.AA RIO1 231-464 45 2.3e-94 319.78 In-house 1-225 (225) Show / Hide 
Range on Protein: 231-464
Range on HMM: 1-225/225
Sequence Identity: 45% (108 aa)

KAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGK-AIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWA
  .||.||....||.  |..  | ||||||||  |.||          .|| |   | |||..||    || |.||.   |||    .| |||| | .||
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHAS-------ETNGKRA---EYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWA

EKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSNEEMK-DAYYQTLHLMQQLYNECTLVHADLSEYNMLWHAGKVWLIDVSQSV
|||| || |.  . ||||  . .| ..|.|.||| |  .||.||.. ... .     | | .  |  .|  | |||||||||||| | .|. .|||||||
EKEMRNLKRIYQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSV

EPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNEREL
|. ||| |||| .|| ||  .|.| .|   . .|..
EHDHPHSLEFLRMDCKNVNMYFMKHNVI-IFPVRDI