Gene PLK3 (Mouse)
PLK3
Sequence
Protein domains of PLK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | PLK3.AA | PLK2 | 63-315 | 69 | 1.8e-228 | 743.33 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-257/257 Sequence Identity: 69% (179 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSR----KSLAHIWKARHTL |..|.||||||||||||.||......||||..|.|||||||||||...||||||.|.|||||.|.|||||.|||||.||.||| ||.||.||.||.| YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL LEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGS .|||||||.|||.|||.||||..|.|||||||||||.||||.|.|||||||||||.|....|.||||||.|||||.||||..|.|.|.|||.|||.|||. TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR PPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF ||||||.||||||||...||..|..||.|||.|.|..|...|.||||...|.||||| PPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF |
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Kinase | PLK3.AA | PLK | 63-315 | 58 | 1.1e-189 | 622.68 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-258/258 Sequence Identity: 58% (152 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR-HTLLEP |..|..|||||||.|||.|| ... ||.||.|.|...|||||||. .|||.||.|.|..||.| |.|||..|.||.||.|...||.|..|.| ..| || YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP EVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVL--LRQGHGPEADVWSLGCVMYTLLCGSP |||||..|| .|||||||..|.||||||||.|..|||..|.||||||.|||....||||.||||||.||||| .|||. |.|.|||||.|||||.|.| EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP PFETADLKETYRCIKQVHYTLPAS--LSLPARQLLAAILRASPRDRPSIEQILRHDFF ||||.|.||||..||. ||..|.. .| .|..|....|. |..||.|.|||.|.|| PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF |
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Kinase | PLK3.AA | PLK-Unclassified | 63-315 | 49 | 1.5e-130 | 440.01 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-264/264 Sequence Identity: 49% (131 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR------- | .|..|||||||.||.... |. ||.|.|| | | .|.| ..||..| .| |..||.| | ||| .|.|| ||.|. ..| .. | | YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK HTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVL--LRQGHGPEADVWSLGCVMYT | |.||..|. ||. .||||||..| |||||||| |..||||.| .|||||..|| ...|||||||||| |||.| |||. | |.||.||. || KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT LLCGSPPFETADLKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRHDFF || | ||||| | | ||. ||. | | . .| |. |. || | ||.| ||. |.|. LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY |
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Kinase | PLK3.AA | PLK1 | 63-315 | 55 | 2.9e-126 | 417.18 | In-house | 1-253 (253) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-253/253 Sequence Identity: 55% (140 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPE |.||| |||||||.||| .|.. .|.||.|.| . |.|||.|. ||..||.|.|||||.| |.||| .|.|| ||||.|.|| . | | .. ||| YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE VRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFE |||..||. | .|||. |.|||||||| |. |....|.|||||| ..| ||||.||||||.||||| ..|| | |.||.||.||.|| |.|||| CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE TADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF | ||||| ||. |..| ..| ||.||. ..| . | || |||.|. .|| TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF |
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Kinase | PLK3.AA | S_TKc | 63-315 | 31 | 1.3e-98 | 334.84 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-231/231 Sequence Identity: 31% (85 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSR--KSLAHIWKARHT--- |...|..|||.|...| ......| .|.|.|. |.|..||.... .| .||.. .|.| |..|...|.|. .| .. | | . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYT . | ..|.|..||...|.|.|..||.||||| | .... ..|..|||||..| .|.||||.|.||||| |.|. ..|.||.||..| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE LLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILR-------HDFF .||| |||. ....... |. | .|.... .|. |..||.. ..|. | .| MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | PLK3.AA | CAMK | 68-315 | 20 | 7.5e-94 | 302.77 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 68-315 Range on HMM: 1-425/425 Sequence Identity: 20% (88 aa) LLGKGGFARCYEATDTESG------------IAYAVKVIPQSRVAK-------------------------PHQREKILNEIELHRDLQ-------HRHI ||.|.|. ......... .|.|.|. ... . |. |.....|||... || |..| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VRFSHHFEDADN-------------------IYIFL---ELCSRK----S-LAHIWKARH--------------TLLEPEVRYYLRQILSGLKYLHQRGI ... ...||... .|... |.|| . .| . .. . | |.|.| |||.|...|.|...| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI LHRDLKLGNFFITDNM-----------------ELKVGDFGLAARLEP-----------------------PEQRKKTICGTPNYVA-PEVLLR------ |||||. | ..||. .|. |||.|....| . | || |||| |.| ||||.. VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM --------QGHGPEADVWSLGCVMYTLLCGSPPFETA-------------DLKETYRCIKQVHYT-LPASLSL-----------------------PARQ ...||..|.||.|...|..||| |||. ...|... |.. |. | .| ... QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD LLAAILRASPRDRPSIEQILRHDFF |. .|. | .|..|||.|.| .. LIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | PLK3.AA | Pkinase | 63-315 | 31 | 7e-87 | 299.75 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-293/293 Sequence Identity: 31% (94 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILN--EIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRK----SLAHIWK-AR |..|| .|.|.|...|.... .|. .|||.|. . .|. ... .. ||.... |.| .|||. . ||| |.||. .|.| .|... . | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR HTLL---EPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMEL----KVGDFGLAARL-EPPEQRKKTICGTPNYVAPEVLL-RQGHGPEADVWS |. . | |.. |..|||.||.|.|..||.|||||. |..| .|... |..|||||. . . . . .|.||||.|.||||.. .|..||..|.|| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS LGCVMYTLLCGSPPFETA------DLKETYRCIKQVHYTLPASLS---------------------LPARQLLAAILRASPRDRPSIEQILRHDFF .||..| .||| ||| . | .. .. |.. . . . . ...... .|. | .||..|||| |..| CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | PLK3.AA | CAMKL | 63-315 | 29 | 7.7e-87 | 277.14 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-297/297 Sequence Identity: 29% (88 aa) YTKGRLLGKGGFARCYEATD-TESGIAYAVKVIPQSRVA-KPHQREK-----------ILNEIELHRDLQ---HRHIVRFSHHFEDADN------IYIFL |. |. ||||.|. ||. |. .|.|.| .. .|. . . | ||.... |. | .|... ...|. .. ||... YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELCSRK---SLAHIWKARH---TLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNM--ELKVGDFGLAARLEP----PEQRKKTICGTPNYV |.|| . .| | .| . |.| | | |||.|...|.|..|| |||.|. | ...|. .|. |||... .| |.| || ||.|.| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEVLLR--Q-GHGPEADVWSLGCVMYTLLCGSPPFETADLK-------ETYRCIKQVHYTLPASLSL-PARQLLAAILRASPRDRPSIEQILRHDFF |||.... . .||..|.||.| ..|...|| ||. .... . |. |.. | | ... ..|.|. .| | .||.|.||..| .. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | PLK3.AA | SAK | 63-315 | 40 | 2.1e-79 | 270.08 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-254/254 Sequence Identity: 40% (102 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR-HTLLEP | . |||||||| | | . . |.|.| . . | ... ||.|.| |.| |. .|||. .|. ||.| . | | . | YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE EVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPF | | ...||. |. ||| ||.|||| | | .| .|..|. |||||. |. |. . |.||||||..||. | || ..|||||||..|||| | ||| EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF ETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF .| |.| . | .|| ||. |. |. .|| | .| ... .| | | DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM |
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Kinase | PLK3.AA | MARK | 63-315 | 34 | 5.2e-76 | 247.98 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-262/262 Sequence Identity: 34% (91 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFE--DADN-IYIFLELCSRKSLAHIWKAR--HT | .. .|.|..| . |... .|. .|.|... . .|...... |||... |.| .|... | .| . . ||. .|..|...| . ||. . YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNM--ELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQG-HGPEADVWSLGCVMYTL | |.| | . |||.|...|.|...| |||.|. | | .|. | |||.... ||.|. .| |||| | |||..|.. ||..|.|||| |.|.. LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICI-PPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM LCGSPPFE--TADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFF .||. ||. |.|.|| |. | .|. | .| .|.|. .| . | .||.||.|..| .. VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | PLK3.AA | ULK | 63-315 | 26 | 7.7e-68 | 231.69 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-324/324 Sequence Identity: 26% (86 aa) YTKGRLLGKGGFA-RCYEATDTES---GIAYAVKVIPQS-RVAKPHQRE------KILNEIELHRDLQ------HRHIVRFSHHFEDA--DNIYIFLELC | . . |||| |. |.... .. . ..|.|.|... |....| .. |||.. . | | |||.. . ||.. .||||..|.| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC SRKSLAHIWKARHT---------LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDN------------MELKVGDFGLAARLEPPE---QRKK | .. | ... | |.|.. ...||..|.|.||...| |||.|. | |... ||..|||.| .. .. | . NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ TIC------GTPNYVAPEVLLRQG----HG-PEADVWSLGCVMYTLLCGSPPFETADLKETY----------------RCIKQVHYTLPA---SLSLPAR |.. ||| | ||..| .|| .. ..|.|||||..| .| |..||.. ..| . ... . .| .| . TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK QLLAAILRASPRDRPSIEQILRHDFF .|. | ..|| |.|.|. | .| DLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | PLK3.AA | ULK | 63-315 | 26 | 2.6e-67 | 229.95 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-329/329 Sequence Identity: 26% (87 aa) YTKGRLLGKGGFARCYEATDTES----GIAYAVKVIPQS-RVAKPHQRE------KILNEIELHRDL--------QHRHIVRFSHHFEDA--DNIYIFLE | . . |||| |.. |.... .. ....|.|.|... |....| . |||.. . | .| .||.. . ||.. .||||..| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME LCSRKSLAHIWKARHT----------LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDN------------MELKVGDFGLAARLEPP---EQ .| | .. | ... | |.|.. ...|||.|.|.||...| |||.|. | |... . ||..|||.| .. . .| YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ RKKTIC------GTPNYVAPEVLLRQG----HG-PEADVWSLGCVMYTLLCGSPPFETADLKETY--RCIKQVHY---------TLPAS---------LS .| ||| | ||..| .|| .. ..|.|||||..| .| | |||.. ..| ..| . . . | .| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS LPARQLLAAILRASPRDRPSIEQILRHDFF ..|. | ..|| |.|... | .| PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | PLK3.AA | TyrKc | 63-315 | 23 | 1.4e-16 | 45.54 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 1-280/280 Sequence Identity: 23% (69 aa) YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDL--QHRHIVRFSHHFEDA-------DNIYIFLELCSRKSLAHIW- |.|. || | | . |..| . | |||.. . || ...|... . | .| .|||. . . ..| .|... .| . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPP--------EQRKKT-ICGTP----NYVAPEVLLRQGHG | |..| .. .. || .| |||.... |||| | ...| |..||||. .. |||. .| |||.. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT PEADVWSLGCVMY-TLLCGSPPFET-----ADLKETYRCIKQVHYTLPASL---------SLPARQLLAAILRASPRDRPSIEQILRHDFF .. |||| | .|. . | .| . . .| ....|| .. . . |. .. | |||. ..| |..| TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | PLK3.AA | Pkinase_Tyr | 63-275 | 27 | 4.8e-14 | 48.2 | Pfam | 1-231 (270) | Show / Hide |
Range on Protein: 63-275 Range on HMM: 1-231/270 Sequence Identity: 27% (63 aa) YTKGRLLGKGGFARCYEATDT----ESGIAYAVKVIPQSRVAKPHQ--REKILNEIELHRDL-QHRHIVRFSHHFE-DADN--IYIFLELCSRKSLAHIW |.|. ||.| | . |..| . . .| |||.... | ..| ||. ..|... . | .| .|||. . . ||| .|.. .| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL KA----RHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARL-EPPEQ-RKKTICGTP-NYVAPEVLLRQGHGPEADVW .. .. | .. . .|| .|. ||..... |||| | .|.|. |..||||| . . . ||.. . | |||.. . ||| RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW SLGCVMYTLLC-GSPP-FETADLKETYRCI-KQ | | .|. .. | | .. . | |. | .. SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED |
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POLO_box | PLK3.AA | POLO_box | 472-535 | 31 | 5.4e-19 | 73.76 | Pfam | 1-74 (74) | Show / Hide |
Range on Protein: 472-535 Range on HMM: 1-74/74 Sequence Identity: 31% (23 aa) YSNKFGFGYQLSSRRVAVL-FNDGTHMALSANRK-TVHYNP--TSTKHFSFSMGS------VPRALQPQLGILR |..| |..|||| | |. |||.|...|..|.| .|.| .. ... ... . .| || .| .|. YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK |
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POLO_box | PLK3.AA | POLO_box | 569-639 | 36 | 1.1e-21 | 83.16 | Pfam | 1-74 (74) | Show / Hide |
Range on Protein: 569-639 Range on HMM: 1-74/74 Sequence Identity: 36% (27 aa) VKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLLVTFVA--RNRSACTYLASHLRQLGC-SPDLRQRLRYAL .|.... ...|.|||||||. ||||.||. .. ..||. . .|. || |.. . || ..||...|.|. YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK |