Gene PLK2 (Mouse)

PLK2

Species: Mouse
Alias: PLK2, Snk
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK2

Sequence

Name Sequence Type Origin Length Description Download
PLK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
PLK2.AA Protein Sugen 682 None Fasta, JSON
PLK2.NA RNA Sugen 2770 None Fasta, JSON

Protein domain

Protein domains of PLK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PLK2.AA PLK2 79-331 75 1.7e-231 753.17 In-house 1-257 (257) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-257/257
Sequence Identity: 75% (194 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSR----RSMAHILKARKVL
|||||.|||||||.||||||.....|||.||.|||||||||||||...|||||| |.|.|.|||.|.|||..|||||||||||    .||||..|.|..|
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

TEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGR
||||||||.|||||||.|||.|.|.||||||||||||..||.|.|||||||||||.||..||.||||||..|||||.|||.||||||||||.|||||.||
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR

PPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
|||||.||||||||||...|.||..|..||.||||.|||..||||||||.|||||||
PPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase PLK2.AA PLK 79-331 59 6.2e-192 630.16 In-house 1-258 (258) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-258/258
Sequence Identity: 59% (153 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-KVLTEP
|.||..||||||||||||||. ...|||.|..|.|...|||||||...|||.|| |||...|.|.|.|||.||.||.||||..||..|..|.| |.||||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVL--NKQGHGCESDIWALGCVMYTMLLGRP
|||||..|||.||||||...|.||||||||.|.|. |..|.||||||.|||. ..|..|.|||||| .||||  |||||..|.|.|.|||.|||.| |.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETTNLKETYRCIREARYTMPSS--LLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
|||| ..||||..|....|..|..  . ..||.||..||..||..||..| |..|.||
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase PLK2.AA PLK-Unclassified 79-331 50 1.9e-134 452.97 In-house 1-264 (264) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-264/264
Sequence Identity: 50% (132 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-------
| ||. ||||||||||..... ..|.||||||| |   |  .|.|   ||..|  ||||..|.|.| ||| ||.|||||||.  .. ...| |       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVL-NKQ-GHGCESDIWALGCVMYT
|.|||.||..|. ||| .|||||   | |||||||| |.|. ||.| .|||||..||  . ...|||||||| .||.| .|. ||. |.|.|..||. ||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

MLLGRPPFETTNLKETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
.| |.|||||   | ||. |.  .|  |  . .   || || . |. ||. ||..| |  |.|.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase PLK2.AA PLK1 79-331 52 2.7e-130 430.63 In-house 1-253 (253) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-253/253
Sequence Identity: 52% (134 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPE
| .|. |||||||.|||..|   ..|.|.|..| | . |.|||.|. .||..|| |||.|.|.|.|.||||.|.||.|| |.|||.  . | || .||||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFE
 |||..||| | .|||...|.|||||||| |.|. ...|.|||||| ..|    |..|.||||||. ||||||.||  | |||..||.||..|.|.||||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE

TTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
|  |||||  |... |..||.. .||..|| .|| ..|. ||  . ... .||
TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase PLK2.AA S_TKc 79-331 31 4.3e-99 336.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSR--RSMAHILKARKV---
|  ....|||.|.|.|  ..   ....| |||.          |.| .||....  ||...|..| .|.| ...|. .|||.    .. ...| |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGC-ESDIWALGCVMYT
   ..| ..|.|..||...|.|.|.. |.|||||  | ...|  ..|..|||||..|       .|.||||.|..||||   |.|. ..|.|..||..| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIR-------HDFF
|| |.|||.  ....... |.            .||..|  .| |.||.||.  .. .       | .|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PLK2.AA CAMK 84-331 20 2.8e-94 304.19 In-house 1-425 (425) Show / Hide 
Range on Protein: 84-331
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

VLGKGGFAKCYEMTDLTNN------------KVYAAKIIPHSRVAK-------------------------PHQREKIDKEIELHRL-------LHHKHV
.||.|.|.| .. ..  ..            . .|.|||. ... .                         |. |... .|||....       |.|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQFYHYFED-------------------KENIYILL---EYCSRR----SMAHILKAR---------------KVLTEPEVRYYLRQIVSGLKYLHEQEI
...|...||                   ....|. .   ||||       .   ....               . .|| |.|.| |||.|...|.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKLGNFFINEAM-----------------ELKVGDFGLAARLEPLE-----------------------HRRRTICGTPNYLS-PEVLNK------
 |||||. |  ... .                  .|. |||.|....| |                       .  .| |||| | . |||||.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QGHGCESDIWALGCVMYTMLLGRPPFETT-------------NLKETYRCIREARYTMPSSLLAP------------------------AKH
        ...| ..|.|..|...|.|| |.|||.               |..|... |....|..|.. . |                        .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIASMLSKNPEDRPSLDDIIRHDFF
|| .|| ..||.|...... .| ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PLK2.AA AGC 79-331 21 5.2e-90 232.19 In-house 1-395 (395) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-395/395
Sequence Identity: 21% (85 aa)

YCRGKVLGKGGFAKCYEMTDL------TNNKVYAAKIIPHSR--------VAKPHQREK-------IDKEIELHRLLH----------HKHVVQ-FYHYF
.   ||.|||.| |.|   .       ...|.|| |..  ..          .  ..|        . .| .   ...          |  .|.  .. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDKEN--IYILLEYCS----------R-RSMAHILK--ARKVLTEPEVRYYLRQ-------IVSGLKYLHE-QEILHRD-LKLGNFFINEAMELKVGDFG
.||..  .|...||..             .. |. .   .....|...|.|. .       ||..| |||. . | ||| ||. |  ..|   .|  |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAARLEP--------------------------------------------------LEHRRRTICG--TPNYLSPEVLNKQGHGCESDIWA--LGCVMY
|. ..                                                     ..|  |.||  ||.|..||.|    .| . |.|.  |||.||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

TMLLGRPPFETTNLK----------ETYRCIR------EARYTMP----------SSLLAPAKHLIASMLSKNPEDRPS----------LDDIIRHDFF
 || |.|||   |            |..  |.      . . ..|          ...   ||.||  .| |.||.|.            ..| .| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PLK2.AA Pkinase 79-331 28 9e-89 306.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-293/293
Sequence Identity: 28% (83 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID-KEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRR----SMAHILK--AR
|..|...|.|.|...|. ..  ..|..| |||. ..  .  .....   ||.... |.|...|..|..|||| .||. .|||       . .....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KVL--TEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMEL----KVGDFGLAARL-EPLEHRRRTICGTPNYLSPEVLN-KQGHGCESDIWAL
...  .| |.. |..||..||.|.|.. |.|||||. |..|.. ...    |..|||||. . .   .   |.||||.|..|||..  |..| ..|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVMYTMLLGRPPFETT------NLKETYRCIREARYTMPSSLL---------------------APAKHLIASMLSKNPEDRPSLDDIIRHDFF
||..| ||.|||||         . .. .. |.....  ... .                      ..|..| ..| |.|..||. ..|  |..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PLK2.AA CAMKL 79-331 28 3.7e-84 268.44 In-house 1-297 (297) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YCRGKVLGKGGFAKCYEMTD-LTNNKVYAAKIIPHSRVA-KPHQREK-----------IDKEIELHRLLH---HKHVVQFYHYFEDKEN------IYILL
|  ||.||||.|.|    |. .|... .| |||  ..   .|. . .           | .||.....|.   |......|. .|..|.      ||. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCSRRS--MAHILKAR----KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAM--ELKVGDFGLAARLEPL----EHRRRTICGTPNYL
||||  .  . . ....    . ..|.| | | |||||...|.|.. | |||.|. |  . | .   .|. |||...  .|     ..  .| ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEVLNK--Q-GHGCESDIWALGCVMYTMLLGRPPFETTNLK-------ETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
.||....  .  .| . |||..| ..|.|. |. ||.  ...       . |. |..  | .|  ...  ....|| .|| .|||.||....| .| ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase PLK2.AA SAK 79-331 40 3.5e-78 265.85 In-house 1-254 (254) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-254/254
Sequence Identity: 40% (102 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-KVLTEP
|  ...|||||||  |    .   .  | |.|    . |    ... .|.|.|  | |  ... | ||||   .|. || |    |   .| | .. || 
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPF
| | ...||| |. |||  .|.|||| | |  .   |..|. |||||. |.  . .  |.||||||.|||.  .  || .||.|.|||..||.|.|||||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

ETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
.|   |.|   .  | | ||. |   |. ||  || |||..| .|. .. | | 
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase PLK2.AA MARK 79-331 32 4.2e-76 248.28 In-house 1-262 (262) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-262/262
Sequence Identity: 32% (86 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFE--DKEN-IYILLEYCSRRSMAHILKAR--KV
|  .|..|.|..|| .  ...  .. .| ||..  .  .|......  |||....|.|.......|..|  .... ||. .||.|. .. . .||.    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAM--ELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQG-HGCESDIWALGCVMYTM
|.|.| | . |||||...|.|.. | |||.|. |  | | .    |  |||.... .| . .  | |||| | .||...|.   | . |||.|| |.|.|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPP-GQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LLGRPPFE--TTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFF
. |. ||.  | ..|| |. |.  .|. |. . . ...|| ..|  |||.||....| .| ..
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase PLK2.AA ULK 79-331 26 7.9e-68 231.66 In-house 1-324 (324) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YCRGKVLGKGGFA-KCYEMTDLTN---NKVYAAKIIPHS-RVAKPHQRE------KIDKEIELHRLLH---HKH--VVQFYHYFEDK--ENIYILLEYCS
||  ..|||| |. | |. ..  .   |...|.|.|. .    |....|      ....||.. . |.   |..  .|..|..||..   |||| .||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

RRSMAHILKARKV---------LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEA------------MELKVGDFGLAARLEP---LEHRRRT
     ...| .|          |.|.|.. ...||..|.|.||.. | |||.|. |  |..               ||..|||.|  ..     .  . |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IC------GTPNYLSPEVLN----KQGHG-CESDIWALGCVMYTMLLGRPPFETTNLKETY----------------RCIREARYTMPS---SLLAPAKH
..      ||| | .|..|.    .. ..  ..||| |||..| || |..||..    ..|                 . .  .. .|.    .    | 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIASMLSKNPEDRPSLDDIIRHDFF
||  || ....|| | ..|. | .|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase PLK2.AA TyrKc 79-331 21 1.2e-16 46.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 79-331
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLL--HHKHVVQFYHYFEDK-------ENIYILLEYCSRRSMAHILK
   ||.|| | | . |. |        | | . ..       || . .|... . |  ||...|..| .  ..       | ..|..||..  .  . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ARKV-LTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL--------EHRRRT-ICGTP----NYLSPEVLNKQGHG
...  |. ..  ..  || .|  |||.. . ||||   |  ..|    |..||||.  ..            | ..  .|        ..||..|.    
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

CESDIWALGCVMYTML-LGRPPFET-----TNLKETYRCIREARYTMPSSLL-------APAK--HLIASMLSKNPEDRPSLDDIIRHDFF
 .||.|. | .|. .. .| .| .       . .| ...... .. ..           .|..   .. .    .|||||.  .|  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PLK2.AA Pkinase_Tyr 134-331 26 5.8e-15 51.3 Pfam 60-270 (270) Show / Hide 
Range on Protein: 134-331
Range on HMM: 60-270/270
Sequence Identity: 26% (58 aa)

L-HHKHVVQFYHYFE-DKEN--IYILLEYCSRRSMAHILKA----RKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAA
| ||...|..|     ..|   ||| .||.   .. . |..    .. || ..   . .|| .|. ||... . ||||   |  ..| .  |..||||| 
LGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

RL-------EPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLL-GRPP-FETTNLKETYRCIREARYTMPSSLLAPAK--HLIASMLSK
 .          .. .  |  .    .||..|      .||.|. | .|. ..  |. | ..     | |. | | .| ||   ..|..  .|. .   .
DIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHY

NPEDRPSLDDIIRHDFF
.|||||.  .|  | ..
DPEDRPTFSEI--HEQL
POLO_box PLK2.AA POLO_box 507-570 33 4.3e-25 94.48 Pfam 1-74 (74) Show / Hide 
Range on Protein: 507-570
Range on HMM: 1-74/74
Sequence Identity: 33% (25 aa)

YSNKYGFGYQLSDHTVGVL-FNNGAHMSLLPDKK-TVHYYA--ELGQCSVFPATD------APEQFISQVTVLK
|..|||..||||..||.|. || . .. |.|..| .|.|..  . .|....| ..       ||.. ...|.||
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK
POLO_box PLK2.AA POLO_box 603-674 34 4.3e-26 97.8 Pfam 1-74 (74) Show / Hide 
Range on Protein: 603-674
Range on HMM: 1-74/74
Sequence Identity: 34% (26 aa)

LKSDKALMMLFNDGTFQVNFYHDHTKIIICNQSEEYLLTYIN--EDRISTTFRLTTLLMSGC-SLELKNRMEYAL
.... ..|.....||.||||..||||||.| ... |..|||.  ... ..|..|.|.| .|| . .|.....|. 
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMK-YAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK