Gene PKN1 (Mouse)

PKN1

Species: Mouse
Alias: PKN1, F730027O18Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: AGC
Family: PKN

Sequence

Name Sequence Type Origin Length Description Download
PKN1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
PKN1.AA Protein Sugen 951 None Fasta, JSON
PKN1.NA RNA Sugen 2990 None Fasta, JSON

Protein domain

Protein domains of PKN1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HR1 PKN1.AA HR1 42-110 31 1.3e-19 73.44 Pfam 1-74 (74) Show / Hide 
Range on Protein: 42-110
Range on HMM: 1-74/74
Sequence Identity: 31% (24 aa)

LERERLKREIRKELKLKEGAENLRRA---TTDLGRS----LAPVELLLRGSARRLDLLHQQLQELHAHVVLPDPAA
. ...|...|..|.|.||||||.|||   |||  ..    .. ..  || | .....|..||..|.....  .|..
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTD-NKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 PKN1.AA HR1 131-203 37 4.6e-21 78.67 Pfam 1-74 (74) Show / Hide 
Range on Protein: 131-203
Range on HMM: 1-74/74
Sequence Identity: 37% (28 aa)

SRVAGLEKQLAIELKVKQGAENMIQTY--SNGSSKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQALQAGELES
.| . |.|....|.|.|.|||||.. |  ... .|.||..  .||||..|..||. .||||..  | .|  . ..
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 PKN1.AA HR1 221-293 32 1.7e-21 80.21 Pfam 1-74 (74) Show / Hide 
Range on Protein: 221-293
Range on HMM: 1-74/74
Sequence Identity: 32% (24 aa)

LRIEELRHHFRVEHAVAEGAKNVLRLL--SGAKAPDRKAVSEAQEKLTESNQKLGLLRESLERRLGELPADHPKG
.|...||.....| .. |||.|..|..  ..... .||. ...| .| |||||. .||..||..  ...  || .
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
Kinase PKN1.AA PKN 624-883 85 1e-204 686.39 In-house 1-260 (260) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-260/260
Sequence Identity: 85% (222 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSE
|...||||||||||||||.....||..|||||||.|||||||||||||||||...|.|..||||||||.|||| |||||||||..|||||.|||.|||||
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDVFSE

PRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESP
|||.||.||||||||.||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||.|
PRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECP

FPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFF
|||||||||||.||||.||||||||.||| |||||||.|||||||..||||||.|.||||
FPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase PKN1.AA AGC 624-883 32 2.3e-180 471.24 In-house 1-395 (395) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-395/395
Sequence Identity: 32% (130 aa)

FKFLAVLGRGHFGKVLLSEFR------SSGELFAIKALKKGD-IVARD--EVESLMCE------------KRILAAVTRAG-------HPFLVN-LFGCF
|.|| |.|.|.|||| | . .      ..|...|.| ||| . || ..  .||  | |            ..||. .   .       |||.|. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPEH--VCFVMEYSA---------GG-DLMLHIHSD----VFSEPRAVFYSAC-------VVLGLQFLHE-HKIVYRD-LKLDNLLLDTEGYVKIADFG
|...|  ..|||||           || .|.||.. .    .|.|.|| || |.       .||.|..||. ..|..|| ||..|.||| .|..|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEGMGYG--------------------------------------------------DRTSTFCG--TPEFLAPEVLTDTSYTRAVDWWG--LGVLLY
||||||..|                                                  |||.||||  |||..|||.|    |..|.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLVGESPFPGD----------DEEEVFDSIV------NDEVRYP----------RFLSAEAIGIMRRLLRRNPERRLGSTERD-----AEDVKKQPFF
|||.| .|| ||          ...|.|..|       |..|..|          |..| ||  ....|| ..||.|||. ..|     ||..|. |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKN1.AA PKC 624-883 53 3.1e-153 500.17 In-house 1-262 (262) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-262/262
Sequence Identity: 53% (142 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSD-VFS
|.|| |||.| ||||.|.| . . |..|||.|||  |.  | ||. |.|||.||  ..  ||||..|. ||||...  |||||  ||||| || .   |.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWK--HPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFK

EPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGES
|..|.||.| ....||||||. |.|||||||| ||| || .||||||.|||.| .||.||||||||...|||.|    |. .|||| .|||.|||..| |
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQS

PFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERD---AEDVKKQPFF
|| |.||.|.|.|| .|...||| || || .|.  .. .|||.|||.....   ..|... |||
PFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase PKN1.AA Alpha 624-883 51 6.9e-123 414.56 In-house 1-259 (259) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-259/259
Sequence Identity: 51% (135 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHI-HSDVFS
| || |||.| ||||.|.| . . ||.||| |||  |.  | ||  | |||.||   .   |||| .  ||||.    |||||  ||||| ||     | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGK--PPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFK

EPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGES
|| |||| | .  || ||||  |.|||||||| .|| || .||||||.|||.|  .. | ||||||...|||.     | ..||||  |||||||..|  
EPHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQP

PFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFF
|| |.||.|.| .| . .| ||. .| ||. | . .| ..| .|||..  . .|... |||
PFDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase PKN1.AA Akt 624-883 43 4.3e-122 392.11 In-house 1-264 (264) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-264/264
Sequence Identity: 43% (116 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELF-AIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSD-VF
| || |||.| ||||.| .  ...... |.|.|||  |.....||  . |..||  .    |||.|||   |||... .|||.|  ||.|  |.. . .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN---HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

SEPRAVFYSACVVLGLQFLHEHKIVYRD-LKLDNLLLDTEGYVKIADFGLCKEG-MGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWG-LGVLLYEML
||.|| || | ..|....||.. |.||| ||. |.|.| .|.....|||||||. . ..|.| ||||||| ||||.| .. .|.|||||| ||...|||.
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

VGESPFPGDDEEEVFDSIVNDEVRYP--RFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFF
 |  ||  .| .. |. | | .|..|  ...| |.  . ..|| ..|..|||... ||...|  |.|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PKN1.AA Eta 624-883 50 4.8e-121 408.43 In-house 1-261 (261) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-261/261
Sequence Identity: 50% (132 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHI-HSDVFS
|.|. |||.| ||||.| | .  .|..||| |||  |.  |.||  |.|||||.   .  |||| .|. ||||.. . |||||  ||||| .| ..  | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARK--HPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFD

EPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGES
|||| || | |.. |.|||.| ..||||||||.||| ||  |.||||.||||.  |  |.||||||...|||.| .  |  .|||| .|||.|||. |..
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQP

PFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTE--RDAEDVKKQPFF
||  | |...|.||..|.| || .|. ||..|..  . .||..|||...   . ..... |||
PFEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase PKN1.AA Delta 624-883 51 4.5e-119 401.88 In-house 1-259 (259) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-259/259
Sequence Identity: 51% (134 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHI-HSDVFS
|.|..|||.| ||||.|.|..   . .|||.|||  ..  |.||. | |.|.||  ..  ||||  ||  ||| ||. |||||  ||||| || ..  |.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWE--HPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFD

EPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGES
| || ||.. ...||||||.. |.||||||||.||| .| .||||||.||| |    ..|||||||...|||..    |...||||  |||.||||.| |
EKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQS

PFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFF
|| |.||.|.|.||.||.  |||....|| .....|. |.||.|||. .  . |... .||
PFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase PKN1.AA SGK 624-883 39 6.2e-107 331.32 In-house 1-283 (283) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-283/283
Sequence Identity: 39% (114 aa)

FKFLAVLGRGHFGKVLLSEFRSS------------------GELFAIKALKKGDIV-------ARDEVESLMCEK-RILAAVTRAGHPFLVNLFGCFQTP
|.|| |.| | ||||.. .  .                   . ..|.| |.|  |.       .. |.   | |.  ||  .    |||.|||   |||.
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMK---HPFIVNLHYAFQTK

EHVCFVMEYSAGGDLMLHIH-SDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL
.   |||.|  ||..  |.     |.|.|| || | .|. |  ||. .|.||||| .|.||| .|.... ||||||||.   | |.||||||| ||||||
WKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

TDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFF
    . |.|||| || .||||..|  ||   . .. .| | | . . |.. |..|  ..  || ..|. ||| | ||....|. |||
RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF
Kinase PKN1.AA S_TKc 624-883 34 1.8e-98 334.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAG--GDLMLHIHSDV-
...| ..|.| |||| .   ...|...||| .|          |... | .||      .||..|.|...||. .|...||||  |  |||. .|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTR-AVDWWGLGVL
      |.| .| || . ....|...|.|.|..|||| .|.|||.   .||.||||...        .||||||...|||||   .|.. ..||| .|..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDA--EDVKKQPFF
|||||.|. |||  .....|. |.          | ||. ..|..|...||.|..  |  .  .|.|. |.|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKN1.AA AktR 624-883 38 1.1e-97 330.86 In-house 1-268 (268) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-268/268
Sequence Identity: 38% (105 aa)

FKFLAVLGRGHFGKVLLSEFR-SSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVF
|.....||.| |||| | . .  .....|.| .|| .|. |   . .  |. |...   . |||.|.|. |||| |.  |.|||..||.|  |.  .  |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEM--CCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKF

SEPRAVFYSACVVLGLQFLHEH-KIVYRDLKLDNLLLDTEGYVKIADFGLCK-EGMG-YGDRTSTFCGTPEFLAPEVLTD-TSYTRAVDWWGLGVLLYEM
|| .| ||.| ..|.|..||.| .|.||||| .|.||| .|.|||.|||| | ..|  | ... .|||||| .|||..|    ....|||| .|...|||
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LVGESPFPGDDEEEVFDSIVNDE---VRYPRFLSAEAIGIMR-RLLRRNPERRLGSTERDAEDVKKQPFF
..|  ||  .. .. |..| . .   . ||  .| ..  .   .|| .||. |||.   ..|..|. |.|
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKN1.AA RSK 627-883 38 1.9e-93 316.74 In-house 1-278 (278) Show / Hide 
Range on Protein: 627-883
Range on HMM: 1-278/278
Sequence Identity: 38% (109 aa)

LAVLGRGHFGKVLLSEFR---SSGELFAIKALKKGDIVARDE-VESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVF-
| |||.| .||| |  .     .| ..| | |||  ||.|.  ..  | | .||....  .|||.|.|.  |||....  .|||  ||.|  |.   .. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQ--QHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

---SEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDT---EGYVKIADFGLCKEG-MGYGDRTSTFCGTPEFLAPEVLT----DTSYTRAVDWWGL
   || .| || | .|| ...||...|..||||..| |.|    || .|. |||.||..   .. .| |||.| |..|||.|.    .  ...|.||| |
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GVLLYEMLVGESPFPG---DDEEEVFDSIVNDE--VRYP--RFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFF
|||.||||.| .|| |   .. .|... | . .  .. |   .||.||  . |..| |.|..|||.  .|||..|. |.|
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PKN1.AA Pkinase 624-883 28 5.2e-83 286.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 624-883
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLM-CEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGG----DLMLHIH-
.... ..|.| ||.| .   ...|...|.| .|| ..    ... .   | .|.. . .  ||. | |...|... |...||||  ||    ||. .|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

--SDVF--SEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYV----KIADFGLCKE--GMGYGDRTSTFCGTPEFLAPEVLT-DTSYTRAVD
  . .|  ||  . ||   .. ||...|...|..||||..|.|.| .|..    ||.||||.|      ..  ..||||||...||||.  .. |...||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

WWGLGVLLYEMLVGESPFPGD------DEEEVFDSIVNDEVRYPRFLS---------------------AEAIGIMRRLLRRNPERRLGSTERDAEDVKK
.|..|..||||| |. ||||.      |. .... |   ....... .                      |.. .....|...|..|..     ||....
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQ

QPFF
 |.|
HPWF
Kinase PKN1.AA Pkinase_Tyr 624-826 27 7.2e-21 71.31 Pfam 1-218 (270) Show / Hide 
Range on Protein: 624-826
Range on HMM: 1-218/270
Sequence Identity: 27% (61 aa)

FKFLAVLGRGHFGKVLLSEFR----SSGELFAIKALKKGDIVARDE--VESLMCEKRILAAVTRAGHPFLVNLFGCFQ-TPEH--VCFVMEYSAGGDL--
 .|. .||.|.||.| . . .    . .   |.| ||       ..   |..| | .|.       || .|.| |.     |.  .. |||| ..|||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQL--GHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

MLHIH---SDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMG---Y-GDRTSTFCGTPEFLAPEVLTDTSYTRAV
 |. |    . .. .. . ... .  |...|...... |||   | |.. .. |||.||||..  .    |   |...       .|||.. .  .| . 
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKS

DWWGLGVLLYEMLV-GESP-FPG
| |  |||..|..  ||.| .||
DVWSFGVLMWEIFTYGEQPTYPG
Kinase PKN1.AA S_TK_X 884-948 31 2.8e-20 74.6 SMART 1-79 (79) Show / Hide 
Range on Protein: 884-948
Range on HMM: 1-79/79
Sequence Identity: 31% (25 aa)

RSLGWDVLLA--RRLPPPFVPTLS----GRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQA--------AFRDFDFVA
|.. || |..  ....|||.|...    . ||.||||.||| |.|.|.|. ..   .. ...         ||.|..|.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PKN1.AA TyrKc 624-877 23 1.6e-17 60.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 624-877
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAV-TRAGHPFLVNLFGCFQTP-------EHVCFVMEYSAGGDL--M
 ... .||.|.||.| . . .   .  |.| ||..       .| .| | ||.  .     || .|.|.|.  ..       | .. |||| ..|||   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGG--HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGY---GDRTSTFCG----TPEF------LAPEVLTDTS
|. | . .. .  . ..  .  | ..||..... |||   | |.. .. |||.||||....  .   | ....          .      .|||.. .  
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTRAVDWWGLGVLLYEML-VGESPFPG-----DDEEEVFDSIVNDEVRYPRFL---------SAEAIGIMRRLLRRNPERRLGSTERDAEDV
.| . | |  ||...|..  |..| ||      . .||.  . . . . .            ..|   ||..  ...|| |   .|   |. 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase PKN1.AA Pkinase_C 903-950 39 1.4e-15 58.02 Pfam 1-46 (46) Show / Hide 
Range on Protein: 903-950
Range on HMM: 1-46/46
Sequence Identity: 39% (19 aa)

TLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFDFVAGG
.....||.||||.||| |.|...|  | | .....|..||.| .|.  
QVKSPTDTSNFDPEFTDEPPMDTP-PDWR-MSSGDQEPFRGFTYVNPD