Gene PKACa (Mouse)

PKACa

Species: Mouse
Alias: Prkaca, PKACa
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
PKACa.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
PKACa.NA RNA Sugen 2274 None Fasta, JSON
PKACa.AA Protein Sugen 351 None Fasta, JSON

Protein domain

Protein domains of PKACa.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PKACa.AA PKA 44-298 69 2.4e-212 711.71 In-house 1-263 (263) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-263/263
Sequence Identity: 69% (183 aa)

FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV-KLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEP
|..|.||||||||||||..||.|||.||||.|.||..|.|||.||..|||.|||....||.| |....|.|...||||||||.||||||.||. ||||.|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

HARFYAA-QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSK-GYNKAVDWWALGVLIYEMAAGYPPFF
||.|||| ||||..|||||...|||||||||.|||..|.|..|||||||.|..|||||||||||||||||.|| |..|.|||||||.|||||.||||||.
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

AD--QPIQIYEKIVSGKVRFPSHFSSDL---KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
..  .|.||||||..||..||.||.||.   |||...|||||||||.||.|||||||||||||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase PKACa.AA AGC 44-298 35 6.4e-194 507.08 In-house 1-395 (395) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-395/395
Sequence Identity: 35% (140 aa)

FDRIKTLGTGSFGRVMLVKHK------ESGNHYAMKILDKQK-VVKLK--QIEHTLNE------------KRILQAVN----------FPFLVK-LEFSF
|. .|..|.||||.|.||..|       .|  ||||.|.|.. .|..|  ..|||..|            ..||. .|           ||.|| | .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDNSN--LYMVMEYVA---------GG-EMFSHLR---RIGRFSEPHARFYAAQ-------IVLTFEYLHS-LDLIYRD-LKPENLLIDQQGYIQVTDFG
.|...  ||.||||.          || |.|.||.   . |||.|..||||||.       ||| .||||| .. |.|| |||||.|.|..|.|  ||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKRVKG-----------------------------------------------------RTWTLCG--TPEYLAPEIILSKGYNKAVDWWA--LGVLIY
..|....                                                     ||||.||  ||||.||||.    |.||.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMAAGYPPFFAD----------QPIQIYEKIV------SGKVRFP----------SHFSSDLKDLLRNLLQVDLTKRFGNLKN-----GVNDIKNHKWF
|| .|||||..|          .| ....||       . ||.||          ..||...|||.. ||..| .|| |...|     |...||||.||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKACa.AA Akt 44-298 50 2.6e-142 457.76 In-house 1-264 (264) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-264/264
Sequence Identity: 50% (132 aa)

FDRIKTLGTGSFGRVMLVKHKESGNHY-AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEP
|| .| || ||||.|.||| | ... | |||.| |.. .. .|.|||. |..||| .|.||.|.| .|| .. .||.||.|. ||| |.||.| .||||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

HARFYAAQIVLTFEYLHSLDLIYRD-LKPENLLIDQQGYIQVTDFGFAK-R-VKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWA-LGVLIYEMAAGY
 ||||.|.|.|  |.||| . |||| |||||.|.|..|.| .|||| .|   .|   .| |.|||||||||||.. .|. ||||||. ||...|||  | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFFADQPIQIYEKIVSGKVRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
|||....  | ..|| ...|.||  . .| . |||.. ||. | .|| |. .|....||.| ||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PKACa.AA SGK 44-298 44 6.00000000001e-133 413.1 In-house 1-283 (283) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-283/283
Sequence Identity: 44% (125 aa)

FDRIKTLGTGSFGRVMLVKHKES------------------GNHYAMKILDKQKVV-------KLKQIEHTLNEK-RILQAVNFPFLVKLEFSFKDNSNL
|| .|..| ||||.|..||||.                   .  ||||.| || ..       | |.  |.. |.  ||. .. ||.|.| ..|     |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSK
|.||.|| |||||.||.| ..|.|. ||||||.||.  |||||.| |||||||||.| | ||..  |||| .|     .  | | ||||||||||... .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
.. ..|||| || . |||  | |||.     | |..| ... ..|  .|.| .||.  ||| | .|| |  |..  .|||| .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF
Kinase PKACa.AA AktR 44-298 45 1.3e-130 440.19 In-house 1-268 (268) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-268/268
Sequence Identity: 45% (122 aa)

FDRIKTLGTGSFGRVMLVKHK-ESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSE
|...| || | ||.|.||..| ...  ||||...|.| ....|..||..|. |..  .|.||.|||...|.....|. .|||..|||.|.||.....|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLLIDQQGYIQVTDFGFAK----R-VKGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAA
  ||||.|||.| .||||.  . |||||||||.|.|. |..  |||| .|    .    .. ..||||||.|||.|.  ||.||.|||||.|..|||| .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYPPFFADQPIQIYEKIVSGK-VRFPSH--FSSDLKDLLR-NLLQVDLTKRFGNLKNGVNDIKNHKWF
|.|||....  |...|| .   ..|| .  ||| .|||.   ||. . .|| |  .||  .||.|.||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKACa.AA RSK 47-298 41 7.4e-111 374.6 In-house 1-278 (278) Show / Hide 
Range on Protein: 47-298
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

IKTLGTGSFGRVMLVKHK---ESGNHYAMKILDKQKVVKLKQ-IEHTLNEKRILQAVN-FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGR---
.| ||.|..| | |.. .    .| .||||.|.| |.|. .  ..||. | .||....  ||.|.|  .|.... ||..|||. |||.| ||.. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQ---QGYIQVTDFGFAKRV----KGRTWTLCGTPEYLAPEIIL----SKGYNKAVDWWALGV
|||  |.||.|.|||. |.||... |.||||||| | |.   .| | .|||||.|      ...| | |.| ||.|||..      .|..||.||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMAAGYPPFFA---DQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
|.||| .|.||| .   ... .| ..| .||  ...|  .  | . |||.| .|..|  || |  ......||.|.||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PKACa.AA PKG 44-298 44 2.5e-108 366.2 In-house 1-260 (260) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-260/260
Sequence Identity: 44% (115 aa)

FDRIKTLGTGSFGRVMLVKHKE-SGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEP
...| ||| | |||| ||. .. .   .|.|.. |. .|. .|.||  .||.|..  . .| |.|   |.|.  .|| ||   |||. . ||  |.| ..
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
 .|||.| .|  |.|||.  .||||||||||. |..||.   ||||||...  ..||| |||||| |||||| ||   .||.||||.|..|   | ||| 
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

ADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
.  |...|  | .|  .. ||.. .   ... . |     | | |..|||.|||| ||||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase PKACa.AA S_TKc 44-298 39 2.6e-107 363.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-231/231
Sequence Identity: 39% (104 aa)

FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAG--GEMFSHLRRIGR---
.. ....| |.||.|....||..| ..|.||..          ||...| .||.  . |..|||  .| | ..|||||||. |  |..|..... ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK-AVDWWALGVLIYEMAA
   |.| |||||..||..  ||.||.  |.|||||||.|.|.   | ..|||.|...     |.||||.|.|||..   ||.| ..|||..|...|||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGV--NDIKNHKWF
|||||   |. ....||.          |...||..|..||.| .|| .  .      |||.| ||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKACa.AA Ciliate-E2b 44-298 36 1.3e-106 324.93 In-house 1-272 (272) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-272/272
Sequence Identity: 36% (102 aa)

FDRIKTLGTGSFGRVMLVKH-KESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIG--RFS
.. || || | || | ||.  |.. . ||||   | ....     | |.|| .|. .|.||..|.  ||||. ..|..||.. |.|.|. .| ||   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

EPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---G---RTWTLCGTPEYLAPEIIL-----SKGYNKAVDWWALGVLI
.  ..|| |.|.|..||||..  ||||.|||| ..|..||.   |.| ||  .   .   || |..|||.|.|||||       |||. .|| |..|.  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YEMAAGYPPFF--ADQPIQIYEKIVSG--KVRFPSHFSSDLK------DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
||.  ||.|.   .. |..||..|...  .. |||...  ..       .|    .|.| .... |       |.|.||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWL-------KSHPWF
Kinase PKACa.AA p70 44-298 36 2.9e-96 326.11 In-house 1-299 (299) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-299/299
Sequence Identity: 36% (109 aa)

FDRIKTLGTGSFGRVMLVKHKE---SGNHYAMKILDKQKVVK-LKQIEHTL-------------------------NEKRILQAVNFPFLVKLEFSFKDN
| ..| || | .| |..|.      .|  |||| | | |.|   |  .||                           |  || .|. ||...| ..|..|
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRT-----------WTLCG
. || . ||  ||| | || | | . |  |.||.. |..  |.||... ||||||||| . .||| .  ||||  |    .|             .|.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
|.|| ||||.. .|.|.|||||.||.|.| |  | ||| .. . .. .||  ||  .. |   . . .||.. ||  . |.| |   . . ||. |..|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase PKACa.AA RSK 44-298 38 7.1e-94 318.18 In-house 1-271 (271) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-271/271
Sequence Identity: 38% (104 aa)

FDRIKTLGTGSFGRVMLVKHK---ESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFS
.. .. .|.|||. | ..| .    .. ||||||..| ...   .   . .|  ||  .. || |||  .| |  ..||.|.  .||..| .| . . ||
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQ----GYIQVTDFGFAKRVKGRTW---TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA
|  ..||.| | |. |||||.. ..||||||| |.| .    | | ..|||||| .....    | |.| .|.|||..  .|. .|.||| .||| ||| 
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

AGYPPFFA---DQPIQIYEKIVSGK----VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
.|..|| .   | | .|  .| .|.       ..  |   ||||| .| .| ..| |.  |||..||.|.||
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase PKACa.AA Pkinase 44-298 32 4.9e-90 310.23 Pfam 1-293 (293) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGG----EMFSHLR--RI
. .....| ||||.| . .|| .|  .|.||..|..  . |...|.. .| .|.. .| |. |.|  .| |....||||||. ||    . |....  | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRF--SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYI----QVTDFGFA----KRVKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWAL
|.|  || ...||. ||.   ||.||   |.|||||||.|||..|.|     ..|||.|       .. ..|.||||.|.|||.|. ...| ..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLIYEMAAGYPPFFAD------QPIQIYEKIVSGKVRFPSHFS---------------------SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF
|...|||. |.|||  .       ..|....| .....|..  .                     ...||.....|..| .|| .       .|..|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase PKACa.AA TyrKc 44-289 20 1e-14 15.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 44-289
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV--NFPFLVKLEFSFKDN-------SNLYMVMEYVAGGEMFSHLR
   .|.|| | ||.|.. . |      | | | . .      .|  ..| ||.  .  . | .|.|     .          |..||||...|   ..||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RIGR-FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR-------TWTLC----GTPE-----YLAPEIILSKGYN
. .. .. ..   .. ||    |||||  .| |||   | |.. .. . ..||| .. ..                  |.        .||| |  . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWALGVLIYEMAA-GYPPFFA-----DQPIQIYEKIVSG-KVRFPSH--------FSSDLKDLLRNLLQVDLTKR--FGNLKNGV
 . | |. ||...|.   | .|          .....|.. .|   . | .         .... .. .   . |  .|  | ...   
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase PKACa.AA S_TK_X 299-351 24 5.9e-13 50.28 SMART 1-79 (79) Show / Hide 
Range on Protein: 299-351
Range on HMM: 1-79/79
Sequence Identity: 24% (19 aa)

ATTDWIAIYQ--RKVEAPFIPKFK----GPGDTSNFD-DYEEEEIRVSINEK-------------------CGKEFTEF
. .|| ..|.  ...|.||.|| |    .|.|||||| ...||... .  ..                   ..  .  |
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PKACa.AA Pkinase_Tyr 114-254 27 0.000632 13.92 Pfam 80-232 (270) Show / Hide 
Range on Protein: 114-254
Range on HMM: 80-232/270
Sequence Identity: 27% (42 aa)

NSNLYMVMEYVAGGEMFSHLRR----IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-------KGRTWTLCGT
| ..|.||||...| . ..||.     .... ..   ...||    |||.|  .| |||   | |.. .. . ..||| |. .       . |. .    
N-QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LP

PEYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPP-FFADQPIQIYEKI-VSG
   .||| |  . .. . | |. |||..|.   |  | .    . ..||.|  .|
IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
Kinase PKACa.AA Pkinase_Tyr 44-60 41 0.554931 3.95 Pfam 1-17 (270) Show / Hide 
Range on Protein: 44-60
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

FDRIKTLGTGSFGRVML
   .|.|| |.||.|..
ITFGKKLGEGAFGEVYK