Gene PHKg1 (Mouse)
PHKg1
Sequence
Protein domains of PHKg1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | PHKg1.AA | PHK | 20-288 | 73 | 3.1e-242 | 811.0 | In-house | 1-273 (273) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-273/273 Sequence Identity: 73% (201 aa) YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVS---GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL |||||||||||||.|||||||.|.||.|||||||||....|..|....||||..|..||..|. ||||||||.|.||||.|.|||||.|.|||||||| YEPKEILGRGVSSTVRRCIHKNTGQEFAVKIIDITGTEHQSENEAEHMREATRQEIHILRQVMEGEGHPNIIQLHDFYETNSFMFLVFDMMPRGELFDYL TEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMD-DGHPGYGKEVDMWS ||||||.||.||.|||.|.|..|..|..|||||||||||||.|||||||..||||.||||.||||||.||||.|||||.|.|||. ..|||||.|||||. TEKVTLSEKKTRRIMRQLFEGVCYMHAHNIVHRDLKPENILCDDNMNIKISDFGFACQLQEGEKLRELCGTPGYLAPEMIKCSMYLENHPGYGQEVDMWA TGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFF .||||||||||.|||||||||.||||||.||||||||||||.|||.|||.|..|.|.||.|..|||.|.|||| CGVIMYTLLAGCPPFWHRKQMMMLRMIMEGKYQFGSPEWDDISDTPKDLISKCLQVDPQQRITAEECLQHPFF |
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Kinase | PHKg1.AA | CAMK | 25-288 | 28 | 1.3e-123 | 400.44 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 25-288 Range on HMM: 1-425/425 Sequence Identity: 28% (120 aa) ILGRGVSSVVRRCIHKPTC------------QEYAVKI-------------------IDITGGGSFSSEEVQELREATLKEVDILQKVSG------HPNI .|||| ..|..|||| | |..|.|| ||...... .... .. |. ..|..|..|..| |||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IQLKDTYET-------------------NTFFFLVF---DLMKRGEL----FDYLTEK---------------VTLTEKETRKIMRALLEVICTLHKLNI |.| ..||. ......|. ... ||| |||..|. .||.|.|...| ... . .|..|| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI VHRDLKPENILLDDNM-----------------NIKLTDFGFSCQLQP------------------------GEKLREVCGTPSYLA-PEIIQ----CSM |||||||||||||||. |||..||||.....| |.|....||||.| | ||... |.| VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM ----DDGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHR-------------KQMLMLRMIMDGKYQFGSPE------------WDDYSDT--------VKD |...|.||...|||| |||.|..| | |||.. . ....|| |||.| .|. ||| || .|| QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD LVSRFLVVQPQDRCSAEEALAHPFF |... |.| |..| ..|..|.||.. LIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | PHKg1.AA | CAMK1 | 20-288 | 40 | 2e-118 | 345.89 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-276/276 Sequence Identity: 40% (114 aa) YEPKEILGRGVSSVVRRCIHKPT---CQEYAVKIIDITGGGSFSSE-EVQELREATLKEVDILQKVS--GHPNIIQLKDTYETNTFFFLVFDLMKRGELF || ....||| |.|..|.|| | ..||.|.|| .| .. ..|. .|| ..|..|..||| |||||.... ||....| || .|.. |||| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK---KKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELF DYLTEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDN---MNIK--LTDFGFSCQLQPGE-KLREVCGTPSYLAPEIIQC-SMDDGHPG | || |||. |.||. .|. . .|...||||||||||.|. |. . || . ||| | .. ..| .. .||||.| |||.. | . . DRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK----DKP YGKEVDMWSTGVIMYTLLAGSPPFWHRK-QMLMLRMIMDGKYQFGSPEWDDYSDT-VKDLVSRFLVVQPQDRCSAEEALAHPFF |.|..|||| ||| |.|| | |||. .. ....|. ..| | ||.||..|| .||... |.| |. | ..|..|.||.. YDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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Kinase | PHKg1.AA | S_TKc | 20-288 | 32 | 2.3e-108 | 367.22 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-231/231 Sequence Identity: 32% (92 aa) YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKR--GELFDYLT || ...|.| ..|..|.|| | ...|.|||. | ...|..||.| .||||..|.|.... .....|.... |.||||. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK EKVT------LTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDDGHPGYGK-E .. . ..| ..|..|. ... . .|...|.||||||||||||. .||..|||...|| . .|||| |.|||.. |||| . KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKCK VDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALA-------HPFF .|.|| |.|.| .|.| |||. ...|...|. |. .||.... |.. |..| .| |||. ||.| CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | PHKg1.AA | Pkinase | 20-288 | 32 | 1.4e-100 | 345.29 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-293/293 Sequence Identity: 32% (99 aa) YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRG----ELFDY |. ....|.| ...|..|.|| |....|||||. . |..... .| |. |.... .||||..|.|..|... .|.... | .|||| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRL---SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY LT--EKVTL--TEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNI----KLTDFGFSCQ--LQPGEKLREVCGTPSYLAPEIIQCSMDDGHP .. .. .. .|.| ...|. .|. . .|. .|.||||||||||.|.|..| |..|||...| . ... . .|||| |.|||.|. |.. ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQ GYGKEVDMWSTGVIMYTLLAGSPPFWHR------KQMLMLRMIMDGKYQFGSPEWDDYS-----------------DTVKDLVSRFLVVQPQDRCSAEEA .||..||||| |.|.| .| | |||... || |...||.... | .|.|.. | .. ||.... | . |..|..||.. YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI LAHPFF | ||.| LQHPWF |
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Kinase | PHKg1.AA | AGC | 20-288 | 22 | 7.5e-96 | 247.65 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-395/395 Sequence Identity: 22% (94 aa) YEPKEILGRGVSSVVRRCIHK------PTCQEYAVKIIDITGGGSFSSEEVQELR----EATLKE------------VDILQKVSG---------HPNII .| . ..|.| . |. . .| | . ||.|... ..... | |. | .||.|... ||.|. FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKH-------KIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIV Q-LKDTYETNTF--FFLVFDLMK---------RG-ELFDYLT---EKVTLTEKETRKIMRA--------LLEVICTLHK-LNIVHRD-LKPENILLDDNM . |. ...... ..| ..|. | ||| .| . ...|...| .. | .. . ||. ..|.||| |||||||||.. KILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERAR-FYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDG NIKLTDFGFSCQLQPGE---------------------------------------------------KLREVCG--TPSYLAPEIIQCSMDDGHPGYGK .|||||||..... .. . || || |.||||. ||| HIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----------YGK EVDMWS--TGVIMYTLLAGSPPFWHR----------KQMLMLRMIMDGKYQFGSP------------EWDDYSDTVKDLVSRFLVVQPQDRCS------- ..| || |..|| .|.| ||| . .| | ||.|.| . . |.. |. |||....|.. | .| ACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFG ---AEEALAHPFF ||| .||.| DKGAEEIKNHPWF |
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Kinase | PHKg1.AA | RAD53 | 20-288 | 33 | 3.1e-88 | 262.87 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-305/305 Sequence Identity: 33% (103 aa) YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSS---EEVQELREATLKEVDILQKVSGHPNIIQLKDTYET-NTFFFLVFDLMKRGELFDY | ..||.| ..|.... | ||| .|.|||| .... .. .. .|| ||.|.. ||.||...| ..| . ...| || ||||. YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDK----KKFFIRCMHTIKKMDQVMNEVEILKKLN-HPCIIRIYDIFDTPQKYYYMVLELMTGGELFNK LT-EKVT---LTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNM------------------NIKLTDFGFSCQLQPGEKLREVCGTPSYLAP . | ..| . . . . ... . || ..|.||||||||||.... ||.|||| | .. |. .. ||||.|.|| IVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAP EIIQCSMD----DGHP------GYGKEVDMWSTGVIMYTLLAGSPPFW-HRKQ----MLMLRMIMD-GKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRC |.| |.. ... ||.|.||.|| |.| |..|.| ||| ...| | . | ||| |..|.||. |. .|||... |.| | | EVI-TSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRY SAEEALAHPFF ...||| || . TIDEALNHPWM |
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Kinase | PHKg1.AA | RSK | 22-288 | 32 | 4e-84 | 285.79 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 22-288 Range on HMM: 1-278/278 Sequence Identity: 32% (93 aa) PKEI--LGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELR--EATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLT |. .| | ...|.|.|. | |.||.|... .. || . . |..|..||. . .||.|..|.....|.. ..|. .... ||||. | LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKK-------AKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQ EKVT---LTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDD---NMNIKLTDFGFSCQ--LQPGEKLREVCGTPSYLAPEIIQCSMDDGHPGYGK .... ..|.| . .|. . . ||.. |.||||||||||.|| . ||||||||..| .. .... |.| |.|||.. . |..| KEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQGGHDK EVDMWSTGVIMYTLLAGSPPFWH---RKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCS-----AEEALAHPFF .| || ||.||..|.| ||| . . .. |. ||. ...|.|. |.. |||... | . |..| . ||| ..||.| ACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | PHKg1.AA | CAMKL | 20-288 | 32 | 7.1e-84 | 267.54 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-297/297 Sequence Identity: 32% (99 aa) YEPKEILGRGVSSVVRRCIH-KPTCQEYAVKIIDITGGG-SFSSEEV------QELREATLKEVDILQKVS--GHPNIIQLKDTYETNTF------FFLV |. . ||.| ..|. ..| . | ...|.||||. . .. . .|. |..... .|||||.| ...|| .. ..|| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV FDLMKRGE--LFDYLTEK----VTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNM--NIKLTDFGFSCQLQP-----GEKLREVCGTPSY . || ||||. .. ..|.|.|.. | ... . .|...|||||.||||||||.|. |||..||||| . .| |.||.. ||.|.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY LAPEIIQCSMDDG--HPGYGKEVDMWSTGVIMYTLLAGSPPFWHR--------KQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAE ||||.| | | .|..||.|| |||.|... | || . .....|| | |.. | | . | ..|| .. |.| | .| ... MAPEIFQ-----GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIH EALAHPFF . . ||.. QIMNHPWM |
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Kinase | PHKg1.AA | CDPK | 20-288 | 39 | 1.9e-83 | 255.84 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-271/271 Sequence Identity: 39% (113 aa) YEPKEILGRGVSSVVRRCIHK-PTCQEY-AVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFD--LMKRGELFDY | |..||.| ..||...|| | || |.||| |. .| . ..|..|| . |||||.. .|. . ....|. . . |||||| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPK------SRVKDKEQQQQFFNEIEILKQLD-HPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDY LTEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLD---DNM----NIKLTDFGFSCQLQP-----GEKLREVCGTPSYLAPEIIQCSMDDG .|| .||||...||| .| . |. |||||||||||||.| |. |||. |.| |.. .. ..|... |||| |.|||..| IIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQ------ HPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFF . | ...| || |||.|.|| |.|||. . .. . ....|||.| ||||. || |||... |.. |..| ||..||.|| | KK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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Kinase | PHKg1.AA | DCAMKL | 20-288 | 39 | 8.3e-82 | 254.2 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-279/279 Sequence Identity: 39% (113 aa) YEPKEILGRGVSSVVRRCIHKPTC-QEYAVKI-IDITGGGSFSSEEVQELREATLK--------EVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKR |. | | | .|| |.|. | ..|| || | || | |. . .| || |.||.. ||.|||| . ..|.| .||. . . YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIK-HPHIIQLYEHWDTETHYYLVMEYVQG GELFDYLTEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDD----NMNIKLTDFGFSCQLQP-GEKLREVCGTPSYLAPEIIQCSMDDGH | ||| .|| . ||.. . .|. | . . || .||||||.|||| |. . . .|| ||| | . | ||||| | ||||.. GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM------E PGYGKEVDMWSTGVIMYTLLAGSPPFWHR--KQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFF ||| .||.|. ||| | || | ||| | || ||. | .|.||. || .|||.|. |.| | |..||. ..|| TGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
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Kinase | PHKg1.AA | RSK | 20-288 | 33 | 1.2e-76 | 260.92 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-271/271 Sequence Identity: 33% (95 aa) YEPKEILGRGVSS---VVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL || .| .|.| | |...|.|| | |.||.|||. .. | . .|..|. . ||.|..|.. ... . ... |.|. |.||| | YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKK------ATRDVKDR--VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRL TEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDN----MNIKLTDFGFSCQLQPGEK-LREVCGTPSYLAPEIIQCSMDDGHPGYGKEV .. ..|.| . .|. .. ||.. ||||||||||||.|| ||..||||. || .. | |.| |.|||.. |... . LKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLK------RQGHDQAC DMWSTGVIMYTLLAGSPPFWHRKQ---MLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSA-----EEALAHPFF | || ||.||. |.| .|| .. | .. | .|.. . .. || .||. |||... | . |. | .| |... ||.| DWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | PHKg1.AA | TyrKc | 20-288 | 21 | 9.5e-12 | -32.75 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 20-288 Range on HMM: 1-280/280 Sequence Identity: 21% (66 aa) YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKV-SGHPNIIQLKDTYETN-------TFFFLVFDLMKRGE . ...||.| .|.... | .. ||| . ||. ..| |. |. ||||..| . ..|. .|. | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD LFDYL-TEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPG-------EKLRE----VCGTPS---YLAPEII | ||| . .|. |. ... . ||. |..|||| |.|...| .| .||| | . . . | . |. .||| | LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI QCSMDDGHPGYGKEVDMWSTGVIMYTLLA-GSPPFWH-----RKQMLMLRMIMDGKYQFGSPE-WDD-----YSDTVKDLVSRFLVVQPQDRCSAEEALA ..| . . | || || |. .. | .| . . ... ...|.. |. .| . .. .. .| ||.. .| ----NYGK--FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-- HPFF | .| HECF |