Gene p70S6K (Mouse)
p70S6K
Sequence
Protein domains of p70S6K.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | p70S6K.AA | p70 | 91-352 | 73 | 7.50000000001e-223 | 746.63 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-299/299 Sequence Identity: 73% (219 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTG ||||.||||||||||||||||||..||||.|||||.||.||||.||||||. ||||||||||||||.||.|||||. FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN GKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTV----------THTFCG ||||||||||.||||||.|||.||.|||||||||.||..||.||||.|||||||||||.|||.||||.||||||||||||||.| |||||| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG TIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK--LNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF ||||||||||||.|||.||||||||.||||||||.|||||||||||||||||.| |.||||||.|.|||.||||||....|.||||.||...|.|||| TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | p70S6K.AA | AGC | 91-352 | 37 | 2.8e-196 | 513.35 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-395/395 Sequence Identity: 37% (149 aa) FELLRVLGKGGYGKVFQVRKVTGA---NTGKIFAMKVLKKAM-IVRNAK-DTAHTKAE------------RNILEEVK----------HPFIVD-LIYAF ||.|.|.|||..|||..|||..| |||..|||||||. ||.. | . .||..| |||||... ||||| | |.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QTGGK--LYLILEYLS---------GG-ELFMQLE---REGIFMEDTACFYLAE-------ISMALGHLHQ-KGIIYRD-LKPENIMLNHQGHVKLTDFG |. . ||...||.. || |||..| .||.| |..|.||.|| | .|| .||. .|||.|| ||||||.|...||.|||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCKESIHDG--------------------------------------------------TVTHTFCG--TIEYMAPEILMRSGHNRAVDWWS--LGALMY |||| . || |.|||| | |||||||| ...|.|||| ||.||| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY DMLTGAPPFTGEN----------RKKTIDKIL------KCKLNLP----------PYLTQEARDLLKKLLKRNAASRLGAGPGD-----AGEVQAHPFF |||| |||.|.| .... .||. ..|. .| .....||.||.||||... . |||.|..| | |...||.| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | p70S6K.AA | RSK | 94-352 | 58 | 4.90000000001e-179 | 601.07 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 94-352 Range on HMM: 1-278/278 Sequence Identity: 58% (162 aa) LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVK-HPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGI--- |.|||.|||||||..||.|. .||.|.||||||||.||...|||.||..||||||... |||||.| |||||.||||||.||..|||||. |..|.. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNH---QGHVKLTDFGLCKE-SIHDGTVTHTFCGTIEYMAPEILM----RSGHNRAVDWWSLGA |.||.||||.|||..|. ||||.|||.||||||||.... .||.||||||.||. ..... |.|||.||||||||.|. ..||..|.||||||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LMYDMLTGAPPFTG---ENRKKTIDKILKCK--LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF |||.||||.|||.| .|||.....|.|.| |..| .||.|||.||..|.|.|. . |||.||.|| |...||.| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | p70S6K.AA | SGK | 91-352 | 47 | 1.3e-150 | 468.69 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-283/283 Sequence Identity: 47% (134 aa) FELLRVLGKGGYGKVFQVRKVTG---------------ANTGKIFAMKVLKKAMIV------RNAKDTAHTKAER-NILEEVKHPFIVDLIYAFQTGGKL |..| |.|||..|||.||... .|..|||||.|. |. . | |..||| .|| .|||||| | ||||| || FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRS |. ..|. |||.| | ||..| || | || ||| ||..|| . |||||||||||.| ||||..||||||||| | . . | ||||| ||.|||.| YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ GHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF .| |.||||.||...|.|..|.||| |.. |.|.. .|..||. . .|.||.. ||... |||. |..|.. |||| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF |
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Kinase | p70S6K.AA | Akt | 91-352 | 51 | 2.3e-147 | 474.18 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-264/264 Sequence Identity: 51% (138 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIF-AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGI |..|.||||| .||||.|.| .|.|.. ||||||| .|. . .|||.|||||. ..||||| | |.||| |||....| .||||| | |... FDFLKVLGKGSFGKVFLVKK---KDTQKWYYAMKVLKKDYIIQKN-QVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR FMEDTACFYLAEISMALGHLHQKGIIYRD-LKPENIMLNHQGHVKLTDFGLCKES-IHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWS-LGALMYDM | ||.| || |||. |..|||.|.||||| ||||||.. ..||..||||||||| | |. .| ||||| ||.||||| || .|||||. ||..|| | FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEM LTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF ..|.||| ..... .||. .... | ... .|..||...||... |||.||.|| |...||.| MCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | p70S6K.AA | RSK | 91-352 | 41 | 1.8e-130 | 439.75 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-271/271 Sequence Identity: 41% (113 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIF .||....|.| ..||. ..|... |.. .|||..||| .. .||. ...||.||... ||||| | |.||..||.|.|.. . ||.|| | ... | YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRD--VKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF MEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQ----GHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDM |. ..||.||| |. .||..||..|||||||| . . ||.|..|||. |... . . |||.|..|||||.|.| || .|.||||.|.||| | SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM LTGAPPFTGENRKKTIDKILKCKLNL-------PPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF |||..|| . .|. . ..|.. || . . ....|| ||| ..|.|. . |||||| .. .. ||.| LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | p70S6K.AA | RSK-Unclassified | 91-352 | 43 | 6.4e-124 | 391.32 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-283/283 Sequence Identity: 43% (125 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE--REG |. | .|.| |||. ||| .| .|.|||||.| ..| | . |.||. .||||| | ..||| .|||..|| ||..| | .| FIKHRLIGQGDFGKVYLVRK---KDTQQIYAMKVLHKHKMIRHNK-IKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEK IFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKES---------------------IHDGTVTHTFCGTIEYMAPEILMR | || . ||..|. .|| .|| ...|||||||.||.| . |||.||||.| .. . .|. | |||| ||.|||.. | CFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRR SGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF || .||||| || .|| || | ||. |.|. | |.| .. .| |. ...|||.||||.|| | |||.. ||| .. .|||| CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | p70S6K.AA | AktR | 91-352 | 45 | 2.4e-112 | 379.55 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-268/268 Sequence Identity: 45% (124 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKK-AMIVRNAKDTAHTKAERNILE-EVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG |.....||||..|||. |.| ...|..|||..|| .| ||... || ||||.| ...||||| | |.||| ||..|.|| ||||| | ... FHVYKCLGKGAFGKVYLVQKKR--DNQKQYAMKMIKKKKIIERNQMH--HTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKK IFMEDTACFYLAEISMALGHLHQK-GIIYRDLKPENIMLNHQGHVKLTDFGLCK-ESIH-DGTVTHTFCGTIEYMAPEILMR-SGHNRAVDWWSLGALMY | |..| || |.| || .|||. |||||||||||.| ||||.||||| | . . . ....|||| ||||||.... |||..||||..|.. | KFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIY DMLTGAPPFTGENRKKTIDKILKCK---LNLPPYLTQEARDLLK-KLLKRNAASRLGAGPGDAGEVQAHPFF |.|| |||. .|.. ..||... . |.|......||.. |||..| ||| . .. |. ||.| EMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | p70S6K.AA | PKA | 91-352 | 42 | 3.9e-110 | 372.2 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-263/263 Sequence Identity: 42% (114 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVD-LIYAFQTGGKLYLILEYLSGGELFMQLEREGI ||....||.| .|.| ..|. . .|...|||.|||. ||| | . |.. |.||| ..|||||| ... ||. .||...|| .|||.| | ..| FEIIQTLGTGSFGRVMLCRHKH---SGNYYAMKMLKKQEIVR-LKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGR FMEDTACFYLA-EISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRS-GHNRAVDWWSLGALMYDML | ...|.|| | .| || ||.. |||||||||||... .||.|.|||| |. . | .| | ||| ||.||||. .. ||...||||.|| | | || FSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML TGAPPFTGE--NRKKTIDKILKCKLNLPPYLTQEA---RDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF .| |||. . . .. .||...|.. |..... | .||.|||| .. |.| ... . |..| AGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | p70S6K.AA | MSK | 94-347 | 41 | 9.1e-110 | 370.97 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 94-347 Range on HMM: 1-277/277 Sequence Identity: 41% (116 aa) LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFME |.|||.|||||.| .||... .|||..|||.|.|| .| .| ..||..|| .|| . .||.|| | ||||. ..||..||..||||| . . . | | LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDE DTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQ---GHVKLTDFGLCKESIHD-GTVTHTFCGTIEYMAPEILMR-----SGHNRAVDWWSLGALM . . ....|. ||. |.||||||.||||||||.. . |||||.|||. .. | ....|.|..|||||.| | .|.. |.||||||... SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVIL YDMLTGAPPFT--GENRK------KTIDK-ILKCKLNLP----PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQ | ||||. ||. .. |. . | | |.|.. ..| ..|.||...|| .. . |||... .| |. YTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK |
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Kinase | p70S6K.AA | S_TKc | 91-352 | 36 | 4.90000000001e-109 | 369.46 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-231/231 Sequence Identity: 36% (100 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSG--GELFMQLEREG .|.||..|||..|||...|.. ||.|.|.|..| |.. |..||.. .||.|| |...||. ..||...||..| |.|| ... | YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG I------FMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNR-AVDWWSLGA | | .|.||...| || ..|..|||.||||||||.|.. |.|..||||... .||||| .|||||.| |... ..||||.| RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC LMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGE--VQAHPFF ..| ||.| ||| . .....||. ..||.|...|.|... . |..| ..| . .||.| ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | p70S6K.AA | Pkinase | 91-352 | 30 | 8.2e-92 | 316.13 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-293/293 Sequence Identity: 30% (93 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDT---AHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGG----ELFMQ ....|..|.|..|.| .| . .||||.|.|..|| . . . | . .| |. ...||.|| |...|......|...||. || .|| YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY LE--REGIF--MEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHV----KLTDFGLCKES-IHDGTVTHTFCGTIEYMAPEILM-RSGHNRA .. |.| | |....||. .| .| ..|..|||.||||||||.....||. |..||||.| . .. ..|||||..|||||... .... .. ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK VDWWSLGALMYDMLTGAPPFTGE------NRKKTIDKILKCKLNLPPYLT---------------------QEARDLLKKLLKRNAASRLGAGPGDAGEV ||.||.| ..| ||.| ||| |. . .. |..|....| . . . .|..|..|..|... ..|.. | .. VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQI QAHPFF ||.| LQHPWF |
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Kinase | p70S6K.AA | S_TK_X | 353-415 | 40 | 4.6e-29 | 103.78 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 353-415 Range on HMM: 1-79/79 Sequence Identity: 40% (32 aa) RHINWEELLA--RKVEPPFKPLLQ----SEEDVSQFDSKFTRQTPVDSPDDSTLSESANQV----------FLGFTYVA |.|.|. |.. ...|||||| .. |..|.|.|| .||..||...|||..||.|..| |.|||||. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | p70S6K.AA | Pkinase_C | 372-417 | 40 | 2.7e-15 | 57.07 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 372-417 Range on HMM: 1-46/46 Sequence Identity: 40% (19 aa) LLQSEEDVSQFDSKFTRQTPVDS-PDDSTLSESANQVFLGFTYVAPS . |..|.| || ||...|.|. ||.. .|.... | |||||.|. QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | p70S6K.AA | TyrKc | 91-352 | 20 | 5e-14 | 4.17 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 91-352 Range on HMM: 1-280/280 Sequence Identity: 20% (62 aa) FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV--KHPFIVDLIYAFQTG-------GKLYLILEYLSGGELF .|...|| | .|.|.. . | |.||. . | .|. .. .|| || |. . .. . |....|| ..| | ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK MQLEREGI-FMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHD-------GTVTHTF--CGT----IEYMAPEILMR | . . . .. . . |. .||.|..| ||| |........|| .||||... .| . ... .| | |||| .. DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY SGHNRAVDWWSLGALMYDMLT-GAPPFTG-----ENRKKTIDKILKC-KLNLPPY--------LTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF . . . | || | .|. ..| |..| | . . | .. . . ||. ..| .. |. ......| . | .| GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF-------SEIHECF |
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Kinase | p70S6K.AA | Pkinase_Tyr | 91-248 | 23 | 4e-07 | 24.74 | Pfam | 1-166 (270) | Show / Hide |
Range on Protein: 91-248 Range on HMM: 1-166/270 Sequence Identity: 23% (41 aa) FELLRVLGKGGYGKVFQVRKV-TGANTGKIFAMKVLKKAMIVRNAKDTAHTKA--------ERNILEEV-KHPFIVDLIYAFQ-TGGK--LYLILEYLSG .....||.| .|.|.. . . ||. | |.|| ..|. .. | .|. . .|| || |. . |. .|...|| . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH GELFMQLER----EGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGT | | | . .. . . . . ..|.... .|..|..| ||| |........|| .||||.. .|.. GDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY |