Gene NEK7 (Mouse)

NEK7

Species: Mouse
Alias: NEK7, Nek7
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK6

Sequence

Name Sequence Type Origin Length Description Download
NEK7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
NEK7.NA RNA Sugen 3008 None Fasta, JSON
NEK7.AA Protein Sugen 302 None Fasta, JSON

Protein domain

Protein domains of NEK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK7.AA NEK6 34-285 90 7.50000000001e-217 720.67 In-house 1-252 (252) Show / Hide 
Range on Protein: 34-285
Range on HMM: 1-252/252
Sequence Identity: 90% (229 aa)

FRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLI
|.||||||.|||||||||.||.|...|||||||||..||||||.||||||||||||||||||||||||||.||||||||||||||.||||||||||||||
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKRLI

PERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ
||||.|||||||||||.||||.||||||||||||||||.|.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ

SPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDI
||||||||||||||||||||||||||.|||||.|||||..||.||||.||||
SPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase NEK7.AA NEK 34-285 41 1.6e-145 489.77 In-house 1-277 (286) Show / Hide 
Range on Protein: 34-285
Range on HMM: 1-277/286
Sequence Identity: 41% (115 aa)

FRIEKKIGRGQFSEVYRASCLLDGVP-----VALKKVQIFDLMDAKARADCI-KEIDLLKQLNHPNVIKYYASFIEDN--ELNIVLELAD-AGDLSRM--
..| ||||.|.|..||.. .  ||       ...||.. .. |. | . ... .|. .||||.|||..||| ||||..   |.|| | ..  |||...  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IKHFKKQKRLIPERTVWKYFVQLCSALDHMHSR-----RVMHRDIKPANVFITATGV----VKLGDLGLGRFFSSKTTAAHS-LVGTPYYMSPERIHEN
 ||. |... ...|...|..|.|.|.||..||.|     ...||||||.|.|.|. .     ||.||.|. . ....|..|.. .|||||||||| ... 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GYNFKSDIWSLGCLLYEMAALQS--PFYG-DKMNLYSLCKKIEQC-DYPPLPSDH-YSEELRQLVNICINPDPEKRPDI
.||.|||||||||.||||..|..  ||.. | ||..||..|| .. .|||.|| . ||..|..|.. ....|||.||..
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSC
Kinase NEK7.AA NEK8 71-286 43 2.9e-94 269.52 In-house 39-270 (278) Show / Hide 
Range on Protein: 71-286
Range on HMM: 39-270/278
Sequence Identity: 43% (102 aa)

MDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPER----------------TVWKYFVQLCSALDHMHS
|. | | .   ||..|. |.|||.| || .|.||| | |..| || | | .|| |  . | . .||                ..  ||.| |||. |||.
MSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQH-QQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQ

RRVMHRDIKPANVFITAT-GVVKLGDLGLGRFFSSKTTAAHS--LVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIE
  . |||.|..|.| |   .|||.|| |.    ..|. .. .  .||||||||||      ||.|||.|.||| ||||. |   | ..  ||  |. || 
HNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEAS--NLPALVWKIM

QC-DYPPLPSDHYSEELRQLVNICINPDPEKRPDIA
||  | |. ||||| |.|.||  |   |||.||. .
QCRAYEPI-SDHYSNEMRMLVHNCLQQDPEQRPSAS
Kinase NEK7.AA S_TKc 34-299 31 1.1e-93 318.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-299
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADA--GDLSRMIKHFKKQK-
..| .|||.| |..||..    .|  ||.|..            . ..||..||. .|||..|.| .| . ..| .|.|..|   ||| ..||. .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-RLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF-KSDIWSLGCLLYE
 . .|| ....|. |.|.||...||....|||.||.|....   ..|..| || |..       ....|||.||.|| .   ||.. |.|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYD--VAKRMHACT
|.. . ||.    ... . |||             |.|...... | . |||||| .  .    .. ..|   
MLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK7.AA Pkinase 34-288 27 7.5e-79 273.07 Pfam 1-287 (293) Show / Hide 
Range on Protein: 34-288
Range on HMM: 1-287/293
Sequence Identity: 27% (80 aa)

FRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCI-KEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAG----DLSRMIKHFKK
..|..|||.| |..||..    .|  ||.|..   .  . | ...    || ..| |||||....| .| ..... .|.|... |    ||...|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

QKRLI--PERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVV----KLGDLGLGRFF-SSKTTAAHSLVGTPYYMSPERIH-ENGYNFKSDIW
... .  .|... .|. |....|...||....|||.||.|..|  .|..    |..| || ..|   . . .....|||.||.|| |   ..|  |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCLLYEMAALQSPFYGD----KMNLYSLCKKIEQCDYPPLPSDHYS-------------------EELRQLVNICINPDPEKRPDIAYV
|.||.||||.  . ||.|.    ... . . ..| .....   .  .|                   ||...... |...||.||| .. .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase NEK7.AA NEK1 34-283 37 8.6e-75 254.78 In-house 1-265 (276) Show / Hide 
Range on Protein: 34-283
Range on HMM: 1-265/276
Sequence Identity: 37% (101 aa)

FRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSRMIKHFKKQKR
. . |.|| | |  .. .    || . ..|  ..   |  | | .  .|  .|. . |||..||. ||.|     | || | .|.||| . |.  | .  
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMK-MQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

LIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFIT--ATG---------------VVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYN
|..| .   .|.|.| || |.|.|...|||||. |.| |    |               .||||| |  |  .. .  |   .||||| ||| .   .||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

FKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRP
 ||||||||| |||  .|  || . ..    |  || |  |||.|. |||.||. ||    . .|. ||
NKSDIWSLGCVLYELCTLKHPFEANNWK--NLVLKICQGTYPPIPP-HYSYELQSLVSQMFKRNPRHRP
Kinase NEK7.AA STE 34-284 25 7.3e-74 251.7 In-house 1-347 (359) Show / Hide 
Range on Protein: 34-284
Range on HMM: 1-347/359
Sequence Identity: 25% (91 aa)

FRIEKKIGRGQFSEVYRASCLL---------------DGVPVALKKVQIFD------------LMDA--KARADCIKEIDLLKQLN--HPNVIKYYASFI
... .|||.| | .||.| .                  |. .| |.. . .            |..   . . . .|||...|..|  |||..||| ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------NELNIVLELADAGDLSRMIK-HFKKQKRL---------IPERTVWKYFVQLCSA-LDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGR
 .       .||.|..|. |.| |. .||  ....|.|         .||  . .. .|.. . |.. || ...||||||||...     ||| | |.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFSSK--------------TTA--AHSLVGTPYYMSPERIHE------NGYNFKSDIWSLGCLLYEMAALQSPFYG-DKM-NLYSLC--KKIEQ------
 ....              |..    ..|||| .|.||.|        .||..|.|||||||.. |||  . |.     | ...     ....|      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---CDYPPLPSD------------------HYSEELRQLVNICINPDPEKRPD
    . ||||..                  ..|.|... .| | . ||.|||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase NEK7.AA CAMK 39-286 21 8.2e-71 227.19 In-house 1-417 (425) Show / Hide 
Range on Protein: 39-286
Range on HMM: 1-417/425
Sequence Identity: 21% (88 aa)

KIGRGQFSEVYRASCLLDG------------VPVALKKVQIFDLMD-------------------------AKARADCIKEIDLLKQ-------LNHPNV
..|||.|..|...   ...            . || | .    | |                         .| |.   .||...|.       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKYYASFIE-------------------DNELNIVL---ELADAG----D-LSRMIKH-----------FKKQKRLIPERTVWKYFVQLCSALDHMHSRR
|| |  .                     |... .|.   |... |    | ... ..|           .  ... ..|| . .|| |.|||....||. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

VMHRDIKPANVFITAT-----------------GVVKLGDLGLGRFFSSK-----------------------TTAAHSLVGTPYYMS-PERIH------
..|||.|| |. ..                   . .|. | |. ..| ..                       .   .  .|||.||. || .       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ENGYNFKSDIWSLGCLLYEMAALQSPFYGD-----------KMNLYSLCKKIEQCDY--PPLP------------SDHYSEE--------LR
        . .|..|.|.||.|..|| |    .|||||           .||.| |..|| ...|  || .             |. |.|         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

QLVNICINPDPEKRPDIA
.|.. . ..|||||. |.
DLIRKMLQVDPEKRMTIE
Kinase NEK7.AA Ciliate-E2 34-285 22 6.7e-64 218.24 In-house 1-356 (365) Show / Hide 
Range on Protein: 34-285
Range on HMM: 1-356/365
Sequence Identity: 22% (84 aa)

FRIEKKIGRGQFSEVYRASCLLDG--------------------VPVALKKVQIFDLMDAKARAD---CIKEID----------LLKQLNHPNVIKYYAS
. . ||||.|.|. ||...  ...                    | . .. . |.   . ..       ..||.          .|.||||||.||.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI--EDNELNIVLELADAGDLSRMIKHF-KKQKRLIP------ERTVWKYFVQLCS---------------ALDHMHSRR-VMHRDIKPANVFITATGVV
|.   || . .|.|... |||   ||.. ||..  |.      |. . ... |...               || ..||.  ..|||||| |...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDLGLGRFFSSKTT-------------------------------AAHSLVGTPYYMSPERIH---------ENGYNFKSDIWSLGCLLYEMAALQSP
|. |.|| .... .                                  .....|||.||.|| .          ..||..|.||||||..||||   . |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGDKMNLYSLCKKIE-QCDYPPL--------------PSDHYSEELRQLVNI----CINPDPEKRPD-I
|         . .... ..|.|.                 .. |.|  .| .     ... |||||.. .
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGW
Kinase NEK7.AA ULK 34-282 25 2.4e-63 216.76 In-house 1-312 (324) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-312/324
Sequence Identity: 25% (80 aa)

FRIEKKIGRGQFS-EVYRASCLLD---GVPVALKKVQIFDLMDAKARAD------CIK-EIDLLKQLN---HPN--VIKYYASFIED--NELNIVLELAD
. . ...| |.|   ||.. .  .   .. || |..... . . | ...       .| || ..|.|.   |||  ..|.|  | ..  | . |..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLSRMIKHFKK-----QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITAT------------GVVKLGDLGLGRFFS---SKTTAAHS
 |||.  ||  ||      |. ..|  . ..| |.|... ..|.. ..||||||.|  |.              ||.|..| |.....       .  ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGDKMNLY----SLCKK-------IEQ--CDYPPL-PSDHYSEELRQL
.|      |||.||.|. ....|    |. .|.|||||||..|||   . ||.......|    .| ..       |..   ..|.  .... |.|...|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VNICINPDPEKR
   ..  |...|
IRRMLQYDEKDR
Kinase NEK7.AA NEK4 34-285 37 6e-63 215.43 In-house 1-248 (257) Show / Hide 
Range on Protein: 34-285
Range on HMM: 1-248/257
Sequence Identity: 37% (97 aa)

FRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLM--DAKARADCIKEIDLLKQLNHPNVIKYYASF-IEDN-ELNIVLELADAGDLSRMIKHFKKQ
. . | .|.| . ||.      |.    .||..   |   . . | .  .|. || || |||...|  |. ||..  | ||.   . ||| |  |  | |
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMF---LKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQ

KRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEM
  ...|. |   |||   ||  || ....||| |  |.|.| . ..|.||.|. |    .   |  ..|||||||||      |..||||||||| .|||
--FLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEM

AALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDI
. |   |    ||  ||  .| |   ||.| . ||..| .||   ..  |.||| |
ITLKHAFDAKDMN--SLIYQIIQGQPPPMPPN-YSQDLQNLVYQMLEKQPTKRPSI
Kinase NEK7.AA ULK 34-282 24 1.1e-62 214.52 In-house 1-317 (329) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-317/329
Sequence Identity: 24% (78 aa)

FRIEKKIGRGQFSEVYRASCLLD----GVPVALKKVQIFDLMDAKARAD-------CIKEIDLLKQLN--------HPNVIKYYASFIED--NELNIVLE
. . ...| |.|  ||.. .  .    .. || |..... .   .  ..        ..||...|.|.        |||..|.|  | ..  | . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LADAGDLSRMIKHFKK------QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITAT------------GVVKLGDLGLGRFFSSK---TT
. . |||.  ||  ||       |. ..|  . ..| |..... ..|.....||||||.|. |.              ||.|..| |.......      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AAHSLV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGD--KMNLYSLCKKIEQ------------CDYPPL-PSDHYSE
 ... |      |||.||.|. ....|    |. .|.|||||||..|||   . |||.   . .|. . | |..             ..|.  .... |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ELRQLVNICINPDPEKR
|...|   ..  |...|
ECKDLIRRMLQYDEKDR
Kinase NEK7.AA TyrKc 34-292 21 2.6e-33 117.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-292
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQL--NHPNVIKYYASFIED-------NELNIVLELADAGDLSRMIK
 . .||.|.|.| |||..      ..|| |...         |.| ..|. ....|  .|||... |.  ...         | ||.|... |||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

HFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSK--------TTAAHSLVGTP-----YYMSPERIHEN
  ...   .. ..  .. .| ..  .. ||... |||.   |. ... ..|| .| || |.  ..        .  . .  |.        |.|| | ..
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYNFKSDIWSLGCLLYEMAALQSPFYGD----KMNLYSLCKKIEQCDYPPLPSD-------HYSEELRQLVNICINPDPEKRPDIAYVYDVA
 ...|||.|| | ...|.  .  . | .    .|. . . ....| ...| | .       . ..|. |.   | . |||.||  . ...  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase NEK7.AA Pkinase_Tyr 34-283 25 1.1e-28 97.82 Pfam 1-261 (270) Show / Hide 
Range on Protein: 34-283
Range on HMM: 1-261/270
Sequence Identity: 25% (69 aa)

FRIEKKIGRGQFSEVYRASCL----LDGVPVALKKVQIFDLMDAKA--RADCIKEIDLLKQL-NHPNVIKYYASFI-EDNE--LNIVLELADAGDLSRMI
 .. ||.|.|.| |||.. .      ...||| |..   .  . ..  |.| ..|. ..||| .|||....|.  . ..    . ||.|..  |||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF--SSKT-TAAHSLVGTPYYMSPERIHENGYNFKSDIW
.  . .|. ..  .  .. .| ...... .|..  |||.   |. .| ..||| .| || |     .   .....       |.|| |... .. |||.|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGCLLYEMAAL-QSP-FYGDKMNLYSLCKKI-EQCDYPPLPSDHYSEELRQLVNICINPDPEKRP
| | |..|.  . ..| ..|  |  . ....| |.  |   . .. ..|. .|   | ..|||.||
SFGVLMWEIFTYGEQPTYPG--MSNEEVYEYIYED-GYRMPCPENCPDEIYDLMKQCWHYDPEDRP