Gene MarkmA9 (Mouse)

MarkmA9

Species: Mouse
Alias: MarkmA9
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MarkmA9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 244 Kinase domain by global Sugen HMM Fasta, JSON
MarkmA9.NA RNA Sugen 1545 None Fasta, JSON
MarkmA9.AA Protein Sugen 514 None Fasta, JSON

Protein domain

Protein domains of MarkmA9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MarkmA9.AA MARK 39-282 49 2.3e-152 501.2 In-house 1-262 (262) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-262/262
Sequence Identity: 49% (130 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLV---KNK-PWFQPGMKEANLMKKIKHPNIVSLLQVIE--TKSR-GYLIMELVEGQELYEYIKNS--GH
| ...|||| .|||| ||.|..||. ||.|..    .|.  |... | |...|||..||||..|..|||  |...  |||||...|.|||.|||.   |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IEEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKG--NTKIIDFGLSTQVKAGDLLDEPCGAYAFGAPELFLWERYDGRKSDLWALGVILYYMV
..|.|||.|| ||.|||.|||...|||||.||.||.|| .|  | ||||||.|.... | .|.. ||.... |||.||...|||.| | |.|||.||.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGKVPFD--SVTIPEL-----AGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
.|..|||  .... ||     .|.|. || ||.|...|...|.||||..|||..|.|||||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase MarkmA9.AA CAMKL 39-282 39 2.4e-132 424.74 In-house 1-297 (297) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-297/297
Sequence Identity: 39% (118 aa)

YNVVRTIGHRTYAKVLLAQH-RLTGTPVAVKVLVKNKPWFQPGMK----------------EANLMKKIK---HPNIVSLLQVIETKSR------GYLIM
|....|.|. ...|| ||.| |.||. ||.|.. |.| |  | ||                |...||...   ||||..|..||||..        ||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVEGQE--LYEYIKNSGH----IEEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKG--NTKIIDFGLSTQVKA-----GDLLDEPCGAYAFG
|...| |  |..||.. ||    ..|.|||..| ||.|||.|||.|||||||.||.||..|..|  | ||||||.|.. .      |..|.. || ... 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFLW--ERYDGRKSDLWALGVILYYMVVGKVPFD--------------SVTIPELAGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
|||.|.   ..|||.| | |..||||| ||.|..|||                 | .. . .| .. || ...||.. ...|||..|||. ..|.|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase MarkmA9.AA CAMK 44-282 23 2.6e-108 350.21 In-house 1-425 (425) Show / Hide 
Range on Protein: 44-282
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

TIGHRTYAKVLLAQHRLTG------------TPVAVKVLVKN-----------------------------KPWFQPGMKEANLMKK-------IKHPNI
|.|. ...|| |..|..|.            . ||.|.. |.                               . .  ..| ..|||       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLLQVIE------------TKSR--------GYLIM---ELVEGQEL----YEYIKNSGH---------------IEEDEARQIFLQILSAVSYCHRHG
..|..|.|            | |.         |..|   |...| ||    ..||.  |.               ..|.|||..| ||.||| ||| |.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPDNIMIDNK-----------------GNTKIIDFGLSTQVKA------------------------GDLLDEPCGAYAFGA-PELFLW-----
||||||||.||..|..                 .| ||||||......                         |... ..||  .. | ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ERYDGRKSDLWALGVILYYMVVGKVPFDSV-------------TIPELA-----GVYP-APCG---------------VSDE--------LE
        ..|.|.|.| |..||||| |..|. ||..              ...||      | |   |                 .|||          
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLSLLMTVNPKYRPTVTEVMKHPWL
||.. ...|.|. |.|......|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MarkmA9.AA AMPK 39-282 41 4e-91 270.77 In-house 1-254 (254) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-254/254
Sequence Identity: 41% (106 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVKNKPWFQPGMK----EANLMKKIKHPNIVSLLQVI-ETKSRGYLIMELVEGQELYEYIKNSGHIEED
| .  |||  |. || .. | |||. ||.|.| | |   |  ..    |  ..|...||.|. | .|| ||..  ...|| | | ||..||   | ..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFGLSTQVKAGDLLDEPCGAYAFGAPELFLWERYDGRKSDLWALGVILYYMVVGKVPF
||.  | ||.|.|.|||||.|||||||| |. .| . | || |||||   | |..|   ||     |||.    .| |.. |.|  ||||| |. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DSVTIPEL-----AGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
|   .|.|     .|.|. |  .|.| .||.. . .|.|  | |. ....|||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase MarkmA9.AA S_TKc 39-282 33 5.3e-88 299.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-231/231
Sequence Identity: 33% (87 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVKNKPWFQPGMKEANLMKKIKHPNIVSLLQVIETKSRGYLIMELVEG--QELYEYIKNSGH------I
| ..|.||. ...|| ...|. ||  ||.|..       .  ..| ...|| .||||| |. |... .. |..||...|   .|..|||. |.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

EEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFGLSTQVKAGDLLDEPCGAYAFGAPELFLWERYDGRKSDLWALGVILYYMVVGK
 | .|| .. ||..|. |||.|||.||||||.||..|.  . ||.||||..|.      .  ||   . |||..    |...|.| |..|.||| |..|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

VPFDSVTIPELAGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMK-------HPWL
 ||.     ... ..   .  |.|. |... .....|. |||. |...       |||.
PPFP-----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MarkmA9.AA NuaK 39-282 39 1.1e-84 222.42 In-house 1-252 (252) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-252/252
Sequence Identity: 39% (99 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVKNKPWFQPGM----KEANLMKKIKHPNIVSLLQVIETKSRGYLIMELVEGQELYEYIKNSGHIEEDE
|.. .| |  || || ||  . ||  ||.|   |.|   .  |    .|  .|  . ||.|..   | | |..  ..||   | |||.|| . . . | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFGLSTQVKAGDLLDEPCGAYAFGAPELFLWERYDGRKSDLWALGVILYYMVVGKVPFD
||..| || ||| |||.|.|.|||||  ||. |...| || |||||   . ...|   ||   .  ||    . | |   | |.|||.|| || |  |||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

SVTIPEL-----AGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
     .|      | |  ||  ||  . |   ...|||..| |. .. .|.|.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase MarkmA9.AA QIK 39-282 37 2.4e-82 279.88 In-house 1-272 (272) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-272/272
Sequence Identity: 37% (103 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVK---NKPWFQPGMKEANLMKKIKHPNIVSLLQVIETKSRGYLIMELVEGQELYEYIKNSGH------
| . ||||   .| | ||.|| | | ||.|.. |   ..  .|    |  .|| ..||.|. |.||.||..  |...|  .. |...|. . |.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------IEEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFGLSTQVKAGDLLDEPCGAYAFGAPELFLWERYDGRKSD
              ..|.|||..| ||.||| |||...|||||||  ||..||  | ||.|||.|   | | ||   ||  .. |||.|. . ||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

LWALGVILYYMVVGKVPFDSVTIPEL-----AGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
 | .||.|| .| |. |||..|...|      | .  |  .| ..|.|    ..|.|. | |.  ...|.|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase MarkmA9.AA Pkinase 39-282 32 2.1e-79 274.93 Pfam 1-293 (293) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-293/293
Sequence Identity: 32% (95 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVKNKPWFQPGMK-----EANLMKKIKHPNIVSLLQVIETKSRGYLIMELVEGQ----ELYEYIK--NS
| ..|.||  ....| ...|. ||  ||||.. | .   .  .      |. .||...||||| |. . |.|.. |..||..||     .|..||.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHI--EEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNT----KIIDFGLSTQ--VKAGDLLDEPCGAYAFGAPELFLWERYDGRKSDLWAL
| .  .|.|.. ...|||... |||..||.||||||.||.|||.|..    ||.||||. |     .  .. .|| . . |||. .  .|.|.|.| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYYMVVGKVPFDSV----------TIPELAG-----VYPAPCGVS-----------------DELEDLLSLLMTVNPKYRPTVTEVMKHPWL
|.|||.|. |. ||..            | .  |      .| .| .|                 .|. |... . ...|| ||| .....|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MarkmA9.AA SNRK 39-282 41 6e-67 218.16 In-house 1-254 (254) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-254/254
Sequence Identity: 41% (105 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVKNKPWFQPG---MKEANLMKKIKHPNIVSLLQVIETKSRGYLIMELVEGQELYEYI-KNSGHIEEDE
| . .|.|.  .| | ||.|  ||  |||||. | |         ..|   || ..||||| |  ||.|. . |||.|| .| ..|.|| |    ..|| 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNK-GNTKIIDFGLSTQVKAGDLLDEPCGAYAFGAPELFLWERYDGRKSDLWALGVILYYMVVGKVPF
||. | ||. |..|||.  .|||||||.|..  .| |  |. ||| | . . |. |.  ||. |. |||. | . ||    |.|.|||||| .| |..||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

----DSVTIPE-LAGVYPAPCGVSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
    || |.   .   |  |  ||||  ||.  ..  .|| | .. |.  |.|.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase MarkmA9.AA Ciliate-E2-Unclassified 39-282 22 3.4e-66 226.22 In-house 1-352 (352) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-352/352
Sequence Identity: 22% (80 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPV-----AVKVLVKNKPWFQPG---------MKEAN-------------LMKKIKHPNIVSLLQVIETKSRGYLI
|.....||.  ..|| ..||. ..  .     . |. ....   .           |.. .             ... ..||.|| .. . ..|   |..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELVEGQELYEYIKNSGH-----------------IEEDEAR-----QIFLQILSAVSYCHRHG-IVHRDLKPDNIMIDNKG---NTKIIDFGLST----
||..||..| .|||....                 ..| .|.     ..| |||.. .|.|. . |.|||.||.||..||.|   . ||||||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----QVKAG---------DLLDEPCGAYAFG----APELFLWERYDGR---KSDLWALGVILYYMVVGKVPFDS---------------------VTIPE
    . . .         ....  || . .     |||..  . ||..   |.| |.||||||.|. |. ||..                     .    
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LAGVYP--------APCGVSDELEDLLS----LLMTVNPKYRPTVTEVMKHPWL
... .         .|...|.| .|...     .. .||..|.|  ....|||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase MarkmA9.AA Ciliate-E2 39-282 21 1e-64 221.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-365/365
Sequence Identity: 21% (80 aa)

YNVVRTIGHRTYAKVLLAQHRLTGT-----------------------PVAVKVLVKNKPWFQPGMKEAN--------------LMKKIKHPNIVSLLQV
|.... ||  ....| ........                         .|.|.. ||.  ..  ..  .              ......||||. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--TKSRGYLIMELVEGQELYEYIKNS-----------GHIEEDEARQIFLQILS---------------AVSYCHRHG-IVHRDLKPDNIMIDNKGNT
 .  ...  ||.||...|..|..||||.           . . | |...|. |||.               |. |.|  . |.|||.||.||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLSTQVK-----------AGDLLDEP----------------------CGAYAFGAPELFLWERYDG--------RKSDLWALGVILYYMVVGKV
||||||||....           .. ...                        || . . ||| .  . ||.         |.|.|.||||||.|. || 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDSVTIPELAGVYPAPCG------------------VSDELEDLLSL----LMTVNPKYRPT-VTEVMKHPWL
||    .  . . .  ||                   .|.|  ||..     .. ..|. |.|   ....|||.
PF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MarkmA9.AA TSSK 87-282 36 5.5e-61 198.9 In-house 69-289 (289) Show / Hide 
Range on Protein: 87-282
Range on HMM: 69-289/289
Sequence Identity: 36% (80 aa)

MKK-IKHPNIVSLLQVIETKS-RGYLIMELVEGQELYEYIKNS------GHIEEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFG
|.| .|||||. ... .|| . . |..||. |.  | |||...      | ..|..||. | |. ||| ||| |..||||||  ||  |  .| |..|||
MRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFG

LSTQVKAGD------LLDEPCGAYAFGAPELFLWERYDGRKSDLWALGVILYYMVVGKVPFDS-----VTIPELAG----VYPA--PCGVSDELEDLLSL
 .  .. .|      |.   || ||  ||| ..   ||. ..| |..||||| ||.|. |||       ....        .|.   |..|.|  ||.. 
FARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRH

LMTVNPKYRPTVTEVMKHPWL
... .|. ||...|...|.|.
MLQPHPCNRPHINEICHHCWM
Kinase MarkmA9.AA Pkinase_Tyr 39-180 26 5.8e-16 54.69 Pfam 1-158 (270) Show / Hide 
Range on Protein: 39-180
Range on HMM: 1-158/270
Sequence Identity: 26% (42 aa)

YNVVRTIGHRTYAKVLLAQHR----LTGTPVAVKVLVKNKPWFQPG-------MKEANLMKKI-KHPNIVSLLQVIETKSRG---YLIMELVEGQELYEY
    ...|.  . .| ..  .     |..|||||.| |.     .        |.||..||.. .|||||.|. |.  ...    |..||....  |..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IKN----SGHIEEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFGLS
 ..     ...   .  |. .|| .. .| ......||||   |.......  || ||||.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase MarkmA9.AA TyrKc 39-282 21 2.2e-15 25.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTPVAVKVLVKNKPWFQPGMKEANLMKKI--KHPNIVSLLQVIETK-------SRGYLIMELVEGQELYEYIKNSGH
    ...|.  . .| ... .   ..||||.| ...   .  |.||..|.|.  .||||| |. |. ..          ...||....  | .|......
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-IEEDEARQIFLQILSAVSYCHRHGIVHRDLKPDNIMIDNKGNTKIIDFGLSTQVKAG-------DLLDE----PC---GAYAFGAPELFLWERYD--GR
 .  ..  .. .|| .  .| |.....||||   |.......  || |||||  .. .       |  .      .     .   ||| .   .|     
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTT

KSDLWALGVILYYMV-VGKVPFDS-----VTIPELA------GVYPAPCG--------VSDELEDLLSLLMTVNPKYRPTVTEVMKHPWL
||| |. || .. .   |. |        ..  |.       .  | |           .||. .. .     .|. ||| .|.  |  .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MarkmA9.AA TSSK 39-69 29 1.1e-05 14.55 In-house 1-47 (289) Show / Hide 
Range on Protein: 39-69
Range on HMM: 1-47/289
Sequence Identity: 29% (14 aa)

YNVVRTIGHRTYAKVLLAQHRLTGTP----------------VAVKV
||| ..||| .|||| .|... .                   ||.|.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKI
Kinase MarkmA9.AA APH 151-181 22 4.7e-05 18.11 Pfam 169-203 (248) Show / Hide 
Range on Protein: 151-181
Range on HMM: 169-203/248
Sequence Identity: 22% (8 aa)

RHGIVHRDLKPDNIMID-NKGNTK---IIDFGLST
. ...|.|..|.|.|.| . ....   .||.. ..
PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDAC
UBA_CAMKL MarkmA9.AA UBA_CAMKL 302-339 36 1.8e-12 42.91 In-house 1-41 (41) Show / Hide 
Range on Protein: 302-339
Range on HMM: 1-41/41
Sequence Identity: 36% (15 aa)

DPDIVDAIQYI--GFQAKDIRESLTKEKF-NEVSAAYYLLE
|..|..  . .  ||. ..|.||| . |. |...|.|||| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL
UBA MarkmA9.AA UBA 302-339 18 8.6e-05 23.16 SMART 1-38 (38) Show / Hide 
Range on Protein: 302-339
Range on HMM: 1-38/38
Sequence Identity: 18% (7 aa)

DPDIVDAIQYIGFQAKDIRESLTKEKFNEVSAAYYLLE
.  ..| .   ||.   ....| . . |.  |...|..
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS