Gene MarkmA7 (Mouse)
MarkmA7
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmA7.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 249 | Kinase domain by global Sugen HMM | Fasta, JSON |
| MarkmA7.NA | RNA | Sugen | 2462 | None | Fasta, JSON |
| MarkmA7.AA | Protein | Sugen | 504 | None | Fasta, JSON |
Protein domains of MarkmA7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmA7.AA | MARK | 28-276 | 51 | 3.4e-168 | 553.68 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-262/262 Sequence Identity: 51% (135 aa) YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIP---KRE-YWCKPLMSEAELLMMADHPNIISLLQVIE--TKKK-VYLIMELCEGKSLYQHIRNA--GY |.|| |||||. |||||.|..||..||.|... . . |.|..|.|.|.... ||||||.|..||| |... .|||||...|..||..|... |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDG--RVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMV |.|.|||..|.|..||.||||...|||||.||.||.. ..| .||||||..|...|||||| ||||.|. |||..|..||||||.|.|.||||||||| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGKIPFDAAS--IEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV .|. |||... ...|.|.|..|||..||..|.....|| .|.| ||| |||. |.|.|||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmA7.AA | CAMKL | 28-276 | 38 | 9.90000000001e-139 | 445.43 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-297/297 Sequence Identity: 38% (116 aa) YEMLGTIGHGGSTKVKLARH-RLTGTHVAVKMIPKREYWCKPLMS----------------EAELLMMAD---HPNIISLLQVIETKKK------VYLIM |... |.|.|. |||||.| |.||..||.|.| |. |..| |. |.....| . |||||.|..||||... .||.| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELCEGKS--LYQHIRNAGY----LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDG--RVKIIDFGLGIQVKP-----GQKLNLFCGTYPFS |.|.| . |...|.. |. ..|.||| .|.|..||.||||..||||||.||.||.. ..| .||||||.... .| ||||. |||..|. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEVLLS--RPYDGPKIDVWTLGVVLYFMVTGKIPFDAASI--------EKLRKQIVAGKYS-VPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV |||.... .||||||.|.| .||.||.||.|. |||.... ....|... .| .....| ...|| ... ||| |||. ..|.|||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmA7.AA | CAMK | 33-276 | 25 | 1.9e-121 | 393.31 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 33-276
Range on HMM: 1-425/425
Sequence Identity: 25% (107 aa)
TIGHGGSTKVKLARHRLTG------------THVAVKMIPKR-----------------------------EYWCKPLMSEAELLMM-------ADHPNI
|.|.|. ||||..|..|. ..||.|.|.|. ....| ...| |.... |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
ISLLQVIE------------TKKK--------VYLIM---ELCEGK----SLYQHIRNA---------------GYLQEDEARALFKQLLSAINYCHNQG
|.|..|.| | .| .|..| |.|.| |...|. |...|.||| .|.|..||..|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IVHRDLKPDNIMVEKD-----------------GRVKIIDFGLGIQVKP------------------------GQKLNLFCGTYPFSA-PEVLLS-----
||||||||.||.. .. . .||||||. ....| |||.. |||| .. | ||||..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------RPYDGPKIDVWTLGVVLYFMVTGKIPFDAA-------------SIEKLRKQIVAGKYS-VPCRLSV-----------------------KLH
.||.|||.|.| .||.||.|..|. ||.. ....| ..| .|||. | .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
HLITLLMTDNPELRPTVAEVMMHPWV
.|| ... .|| |.|..... |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmA7.AA | S_TKc | 28-276 | 34 | 1.2e-94 | 321.65 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-231/231 Sequence Identity: 34% (90 aa) YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEG--KSLYQHIRNAGY------L ||.| .||.|. ||...||. || .||.|.|. . ...| ..|.. .||||. |. |... ...|..||.|.| .|...|.. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF QEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGK | .|| ...|...|..|||..||.||||||.||.. . ..||.|||| |. . |||| . ||||| .|...|.|.| .|..|| |..|. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY IPFDAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMM-------HPWV ||. .... |.|. | . ..| ... .|| |||. |.. |||. PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmA7.AA | NuaK | 28-276 | 39 | 3.3e-90 | 237.3 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 28-276
Range on HMM: 1-252/252
Sequence Identity: 39% (101 aa)
YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMS----EAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDE
||.. | | | |||||. . || ||.| |.| . | | |.. .||.||. | | | |. ..|| | || | . . | | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE
ARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKIPFD
|| .| | ||. ||| .|.||||| ||. ... .|| |||| . .. |. ||| . ||. .|| || .| | |||.|| || | |||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD
AASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
.| ||| |.| ||. |. || ... ||. | |. .. |.||
GHDFKHLVKQISQGAYYEPCKPSDA-CMLIRWMLMVNPRRRATIYDICHHWWV
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| Kinase | MarkmA7.AA | AMPK | 28-276 | 38 | 1.3e-87 | 260.19 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-254/254 Sequence Identity: 38% (97 aa) YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKR----EYWCKPLMSEAELLMMADHPNIISLLQVI-ETKKKVYLIMELCEGKSLYQHIRNAGYLQED | . ||| | . |||.. | |||. ||.| . |. . . . .| ..| . ||.|| | .|| ||.. ...|| | |. | | |||. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER EARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKIPF ||. .|.| .|.. |||. .|||||||| |. .. ..|| |||| | |..| || |||. ...| ||..|.| ||.|| |. |. || EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF DAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV | .. .| | |..|.|..| || . . || . . .|. | |. ... ||| DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MarkmA7.AA | QIK | 28-276 | 37 | 3.6e-87 | 295.9 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 28-276
Range on HMM: 1-272/272
Sequence Identity: 37% (103 aa)
YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPK----REYWCKPLMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGY-----
|.. ||| | ||||||| | | ||.| | | .|. | . | ... | .||.|| |.||.||.. |...| |.. .. .. . |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM
---------------LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKI
..|.||| |.|..||. |||...||||||| ||. .. .||.|||.. |.|| |. .||. |. |||... . |||||.
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV
DVWTLGVVLYFMVTGKIPFDAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV
|.| .||||| .|.|..||| ....||. .. ||. .| .|. . ||| .. .|| | |.. .. |.|
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmA7.AA | Pkinase | 28-276 | 29 | 3.1e-85 | 294.27 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-293/293 Sequence Identity: 29% (87 aa) YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMS-----EAELLMMADHPNIISLLQVIETKKKVYLIMELCEGK----SLYQHIR--NA |. ...|| |.. .|....|. || |||| |.||. .. ... |.... . .||||. |. . |.|...|..||.||| .|. .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GYL--QEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRV----KIIDFGLGIQ--VKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTL | . .|.|.. ..|.|....|||..||.||||||.||.. ..| . ||.|||| | ... .. ||||... ||||.....|.|||.|.| . GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVVLYFMVTGKIPFDAA------SIEKLRKQIVAGKYSVPCRLS---------------------VKLHHLITLLMTDNPELRPTVAEVMMHPWV |..|| |..|. ||. . . .. ..| .... .. . . ..|. . . .|. ||| .... |||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmA7.AA | SNRK | 28-276 | 42 | 8.1e-78 | 254.35 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-254/254 Sequence Identity: 42% (107 aa) YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKR---EYWCKPLMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHI-RNAGYLQEDE |.. |.|.| |||||| || .||||.| | | |. | . . ||||. | ||.|. |.|||.|| .| .| .| . |.|| YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL ARALFKQLLSAINYCHNQGIVHRDLKPDN-IMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKIPF || |.|.. ||.||| .|||||||.| . || | ||. ||| . .||.||. .|| .||||.|| || | .|.| |||.|| .| |. || ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF DAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV . | .|. ||.|| ..| . . ||. .. .|. | .. |. |.|| QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MarkmA7.AA | TSSK | 28-276 | 32 | 5.1e-73 | 238.99 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-289/289 Sequence Identity: 32% (94 aa) YEMLGTIGHGGSTKVKLARHRLTGTH----------------VAVKMIPK----REYWCKPLMSEAELLMM-ADHPNIISLLQVIETKK-KVYLIMELCE |.. .|||| ||..|... . . ||.| | . ..| | | | . . . .||||| ... .|| |.|..||..| YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE GKSLYQHIRNA------GYLQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQ------KLNLFCGTYPFSAPEVL . | ..|.. | |.|..||..|.|. ||. |||. ..|||||| || |....|..||| . ..... .. ||| | .|||.| HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL LSRPYDGPKIDVWTLGVVLYFMVTGKIPFDA--ASIEKLRKQIVAGKYSVP----CRLSVKLHHLITLLMTDNPELRPTVAEVMMHPWV ...|||. . ||| .||.|| ||.|. ||| | |. .|. . | . | | .| .|| ... .| .||.. |.. |.|. RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | MarkmA7.AA | Ciliate-E2 | 28-276 | 22 | 5.4e-73 | 248.82 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-365/365 Sequence Identity: 22% (86 aa) YEMLGTIGHGGSTKVKLARHRLTGTH-----------------------VAVKMIPKREYWCKP----LMSEAE----------LLMMADHPNIISLLQV |. . || |. .|......... .|.|.. |.. . .| | . .| .||||| . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TKKKVYLIMELCEGKSLYQHIRNA-----------GYLQEDEARALFKQLLS---------------AINYCHNQG-IVHRDLKPDNIMVEKDGRV . .....||.||.|.|..|...|.| .|. | |.. ..||.|. |..|.|... |.|||.||.||.. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KIIDFGLGIQVKPGQKLNL--------------------------------FCGTYPFSAPEVLLSRPYDG--------PKIDVWTLGVVLYFMVTGKIP ||||||| .... .. .. .|||... |||.| . .||. |.|.| |||.||.|..|| | KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FDAASIEKLRKQIVAGKYSVPCR------------------LSVKLHHLITL----LMTDNPELRPT-VAEVMMHPWV | .|| .|.. || .| . .|| .. .|| |.| ... ||| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | MarkmA7.AA | Ciliate-E2-Unclassified | 28-276 | 23 | 4.3e-70 | 239.18 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-352/352 Sequence Identity: 23% (83 aa) YEMLGTIGHGGSTKVKLARHRLTGTHV-------AVKMIPKREY------------WCK----------PLMSEAELLMMADHPNIISLLQVIETKKKVY |... .||.|| ||....|. .. . .... .. . ... .| . .| . .||.|. .. . ..|...| YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQ--ILLNHPHPFIVKMFYCFQDKQNIY LIMELCEGKSLYQHIRN-----------------AGYLQEDEAR-----ALFKQLLSAINYCHNQG-IVHRDLKPDNIMVEKDG---RVKIIDFGL--GI ..||.|||..| |.|.. ..| .|. .|.|.|....|.| .. |.|||.||.||.. ..| ..||||||. . IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY QVKPG--------------QKLNLFCGTYPFS----APEVLLSRPYDGP---KIDVWTLGVVLYFMVTGKIPFDAASIEK----------------LRKQ | .. |... ||||. . ||||| . ||.. |.|.|.|||.||.|..|. ||.. . |. |... QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN IVAGKYSVPC--------RLSVKLHHLIT----LLMTDNPELRPTVAEVMMHPWV | ......|. ..| . ..|. .. ||. |.| ... ||| IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | MarkmA7.AA | Pkinase_Tyr | 28-168 | 25 | 5.6e-17 | 58.12 | Pfam | 1-157 (270) | Show / Hide |
Range on Protein: 28-168 Range on HMM: 1-157/270 Sequence Identity: 25% (40 aa) YEMLGTIGHGGSTKVKLARHR----LTGTHVAVKMIPKREYWCKP-----LMSEAELLMMA-DHPNIISLLQVIE-TKKK--VYLIMELCEGKSLYQHIR ... ..|.| .|.... . |...|||||. | . . .|.||.... .||||..|. |. .. .|..||.... .|. . | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR N----AGYLQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGL . . | . | .. .| ......|||| |..|.... ||| |||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL |
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| Kinase | MarkmA7.AA | TyrKc | 28-276 | 21 | 3.9e-16 | 38.24 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 28-276 Range on HMM: 1-280/280 Sequence Identity: 21% (61 aa) YEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPKREYWCKPLMSEAELLMMA--DHPNIISLLQVIETK-------KKVYLIMELCEGKSLYQHIRNAGY ... ..|.| .| ... . . |||||. . . .|.||..... .||||. |. |. .. . ....||.... .| ...|. . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPG------QKLNLF----CGT--YPF--SAPEVLLSRPYDGPKI |. .. | . .| | ....|||| |..| ....||| |||| .. . .. .| | |||.. . . .| KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS DVWTLGVVLYFMVT-GKIPFDA-----ASIEKLRKQIVAGKYSVPCRL---------SVKLHHLITLLMTDNPELRPTVAEVMMHPWV ||| ||... . | |. | | . ..... .|.. . . ... ... .|| ||| .|. | DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | MarkmA7.AA | APH | 119-167 | 22 | 0.000505 | 14.6 | Pfam | 151-200 (248) | Show / Hide |
Range on Protein: 119-167 Range on HMM: 151-200/248 Sequence Identity: 22% (12 aa) LQEDEARALFKQLLSAINYCHNQGIVHRDLKPDNIMVE--KDGRVK--IIDFG .|.. .. |. .|... ...|.|..|.|.|. || .||.. RQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWD |
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| UBA_CAMKL | MarkmA7.AA | UBA_CAMKL | 296-333 | 36 | 5.8e-13 | 44.64 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 296-333 Range on HMM: 1-41/41 Sequence Identity: 36% (15 aa) DPAIVKAMGHI--GFQAQDIEDSLRQRKF-NETMASYCLLK |. |.. | .. ||. ..|..|||..|. |. .| |.|| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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