Gene MarkmA12 (Mouse)
MarkmA12
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmA12.AA | Protein | Sugen | 521 | None | Fasta, JSON |
| MarkmA12.NA | RNA | Sugen | 1563 | None | Fasta, JSON |
| MarkmA12.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 249 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of MarkmA12.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmA12.AA | MARK | 39-287 | 50 | 2.6e-152 | 501.04 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-262/262 Sequence Identity: 50% (131 aa) YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLV---KNK-PWFQEAMKEANILKKIKHPNIVSLLQVIE--TKTR-GYLILELVEGQELYEYIKTS--GH ||...|||||..||| ||.|..||. ||||.. .|. |... | |..|.||..||||..|..||| |... |||.|...|.|||.||| |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKG--NIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMV ..|. ||.|| ||.||| ||| ..|||||.||.||.|| .| ||||||||.|....||. |...||.... ||| ||...|||.| | .||||| .|| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV VGKVPFDSFI--NPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL .|..||| . ||......|.|. | ||||...|..||.|| |..|||..|.|||||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmA12.AA | CAMKL | 39-287 | 39 | 2.2e-129 | 415.15 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-297/297 Sequence Identity: 39% (117 aa) YKVIRTIGHGTFAKVLLAQH-RLTGTSVAIKVLVKNKPWFQEAMK----------------EANILKKIK---HPNIVSLLQVIETKTR------GYLIL |....|.|.|.|.|| ||.| |.||. ||||.. |.| | . || |..|.|... ||||..|..||||.. ||.. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELVEGQE--LYEYIKTSGH----IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKG--NIKIIDFGLSTQFKP-----GEILKEHCGAYAFG |...| | |..||. || ..|. ||..| ||.||| ||| |||||||.||.||..|..| ||||||||.|....| |. ||..|| ... EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APERFLG--QRYDGTKSDLGALGVVLHYMVVGKVPFDSFINP---------ELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL ||| |.| ..||| | | ..||.| ||.|..||| .. ... . . .| .. || ...||......| |..|||. ..|.|||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmA12.AA | CAMK | 44-287 | 23 | 2.8e-109 | 353.39 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 44-287
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)
TIGHGTFAKVLLAQHRLTG------------TSVAIKVLVKN-----------------------------KPWFQEAMKEANILKK-------IKHPNI
|.|.|.|.|| |..|..|. . ||||.. |. . .. ..| .|.|| ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VSLLQVIET-------------------KTRGYLIL---ELVEGQEL----YEYIKTSGH---------------IEEDKARQIFIQILSAVGYCHGHGI
..|..|.|. ... |... |...| || ..||. |. ..|. ||..| ||.||| ||| |.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPDNIMIDNK-----------------GNIKIIDFGLSTQFKP------------------------GEILKEHCGAYAFGA-PERFLG------
|||||||.||..|.. .||||||||....|.| |. .|. || .. | || ..|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------QRYDGTKSDLGALGVVLHYMVVGKVPFDSF-------------INPELQRQVVAGVYP-AHCG---------------VSKE--------LED
..|.| |.| ..||.| |..|. ||.. .|| ... .| | . .|.| |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LLSRLMTVIPKYRPTATEVMKHPWL
|......| |. |.|......|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmA12.AA | AMPK | 39-287 | 42 | 1.5e-88 | 262.98 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-254/254 Sequence Identity: 42% (109 aa) YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMK----EANILKKIKHPNIVSLLQVI-ETKTRGYLILELVEGQELYEYIKTSGHIEED | . ||| ||| || .. | |||. ||||.| | | |. .. | |||...||.|. | .|| ||.| ....| | | ||..|| | ..|. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER KARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGKVPF |. | ||.|.| ||| |.|||||||| |. .| . |||| ||||| | || || || ||| |..| |.. |. ||.| |. |. || EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF DSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL | |.| . ...|.|. .|.| .||.... .| | | | ....|||. DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MarkmA12.AA | S_TKc | 39-287 | 34 | 1.3e-86 | 294.92 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-231/231 Sequence Identity: 34% (90 aa) YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMKEANILKKIKHPNIVSLLQVIETKTRGYLILELVEG--QELYEYIKTSGH------I |...|.||.|.|.|| ...|. || ||||.. . ...| .|||| .||||| |. |... .. |...|...| .|..||| |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF EEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGK | || .. ||..|. ||| |||.||||||.||..|. .|||.||||..|. . || . ||| . |.. |.| ..|..| |..|. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY VPFDSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMK-------HPWL ||. .... ... |.|. |........ |. |||| |... |||. PPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmA12.AA | QIK | 39-287 | 38 | 2e-83 | 283.48 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 39-287
Range on HMM: 1-272/272
Sequence Identity: 38% (105 aa)
YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVK---NKPWFQEAMKEANILKKIKHPNIVSLLQVIETKTRGYLILELVEGQELYEYIKTSGH------
| . |||| | || | ||.|| | | ||||.. | .. .| | |.| ..||.|. |.||.||. |.. | .. |...|. |.
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV
--------------IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSD
..|..||..| ||.||| ||| ..||||||| ||..|| ||||.|||.| ||.|. |. || .. ||| |.|. ||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD
LGALGVVLHYMVVGKVPFDSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
.|||| .| |. |||. ..|.. |. | . .|...|.| . ..| |. | | ...|.|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmA12.AA | Pkinase | 39-287 | 30 | 4e-78 | 270.65 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-293/293 Sequence Identity: 30% (89 aa) YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMK-----EANILKKIKHPNIVSLLQVIETKTRGYLILELVEGQ----ELYEYIK--TS |...|.|| |.|..| ...|. || ||.|.. | . .. . |. |.|...||||| |. . |.|.. |...|..|| .|..||. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GHI--EEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNI----KIIDFGLSTQ--FKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGAL | . .|. .. .. |||... ||| .||.||||||.||.|||.|.| ||.||||. | ... .. || . . ||| .|..|.|.|.| .. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVVLHYMVVGKVPFDSF------INPELQRQVVAGVYPAHCGVS---------------------KELEDLLSRLMTVIPKYRPTATEVMKHPWL |..|..|. |. ||.. .. ... . .. .. . .|. |..... .. || ||||.....|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmA12.AA | SNRK | 39-287 | 40 | 2.8e-70 | 229.24 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-254/254 Sequence Identity: 40% (104 aa) YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNK---PWFQEAMKEANILKKIKHPNIVSLLQVIETKTRGYLILELVEGQELYEYI-KTSGHIEEDK | . .|.|.| || | ||.| || ||.||. | | . ..| .| ..||||| | ||.|.|. |||||| .| ..|.|| | ..|| YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL ARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNK-GNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGKVPF ||. | ||. |. ||| .|||||||.|.. .| | .|. ||| | .|.||| |. ||. |. ||| || || |. .|||.|. .| |..|| ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF DSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL . . | ... | ||.| ||. ... || | . |. |.|. QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MarkmA12.AA | CAMK-Unique | 39-287 | 25 | 4.6e-69 | 227.07 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 39-287
Range on HMM: 1-363/363
Sequence Identity: 25% (91 aa)
YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVK-----NKPWFQ----------------EAMKEANILKKIKHPNIVSLLQV----IETKT-------
|| .| ||||.| .|. .. | ||. |.|.. | .| | ....|..|.|. .||||. |... ....
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------RGYLILELVEGQELYEYIKT--------------------SGHIEE--DKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGN-----
. |...|...| .|...| || .| ...|. ..|||| | | .|||||||..|||. . ..
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
-----------IKIIDFGLSTQFK--PGE-ILKEHCGAYAFGAP--------------ERFLGQRYDGTKS---DLGALGVVLHYMVVGKVPFDSFINP-
||..||||.... . .... || . || | .|.||. | |. .|||...|| .|. |||. ..
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------ELQRQVVAGVY-----PAHCG---VSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
|. . .| | .. | .|.|. |.. ..|||.|..| .| | .|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | MarkmA12.AA | Ciliate-E2 | 39-287 | 22 | 1.1e-68 | 234.52 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-365/365 Sequence Identity: 22% (85 aa) YKVIRTIGHGTFAKVLLAQHRLTGT-----------------------SVAIKVLVKNKPWFQE----AMKEAN----------ILKKIKHPNIVSLLQV ||.|. || |.|..| ........ .|.|.. ||. ... |.| | ||....||||. . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TKTRGYLILELVEGQELYEYIK------------TSGHIEEDKARQIFIQILS---------------AVGYCHGHG-IVHRDLKPDNIMIDNKGN . ... ||..|...|..|..||| . . | ....|. |||. |. |.| . |.|||.||.||.. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- IKIIDFGLSTQFKP-----------GEILKEH----------------------CGAYAFGAPERFLGQRYDG--------TKSDLGALGVVLHYMVVGK |||||||||..... .... . || . . ||| . |. ||. .|.|. .|||.|..|. || IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK VPFDSFINPELQRQVVAGVYP------------------AHCGVSKELEDLLSR----LMTVIPKYRPT-ATEVMKHPWL || |.| . . . .|.| ||... .. . |. |.| . ....|||. PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | MarkmA12.AA | Ciliate-E2-Unclassified | 39-287 | 24 | 1.7e-67 | 230.53 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 39-287
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)
YKVIRTIGHGTFAKVLLAQHRLTGTSV-----AIKVLVKNKPWFQE---------AMKEAN-------------ILKKIKHPNIVSLLQVIETKTRGYLI
||.|..||.| |.|| ..||. .. . ..|. .... .. .|.. . ||. ..||.|| .. . ..| |..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV
LELVEGQELYEYIKTSGH-----------------IEEDKAR-----QIFIQILSAVGYCHGHG-IVHRDLKPDNIMIDNKG---NIKIIDFGLSTQFK-
.|..||..| .||| ... ..| .|. ..| |||.. |.| . |.|||.||.||..||.| .|||||||.| . .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------------PGEILKEHCGAYAFG----APERFLGQRYDG---TKSDLGALGVVLHYMVVGKVPFDS---------------------FINPEL
. .... || . . ||| . || ||. |.| .|||.|..|. |. ||.. ... .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK
QRQVVAGVYP---AHCGVSKELEDLLS----RLMTVIPKYRPTATEVMKHPWL
|... .| .....|.| .|... ... . |..|.|. ....|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | MarkmA12.AA | TSSK | 86-287 | 36 | 8.3e-62 | 201.63 | In-house | 68-289 (289) | Show / Hide |
Range on Protein: 86-287 Range on HMM: 68-289/289 Sequence Identity: 36% (80 aa) ILKK-IKHPNIVSLLQVIETKT-RGYLILELVEGQELYEYIKTS------GHIEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDF |..| .|||||. ... .|| . |...|. |. | |||... | ..|..||. | |. ||| |||.|..|||||| || | .|||..|| IMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDF GLSTQFKPGE------ILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGKVPFDS---FINPELQRQV-VAGVYPA--HCGVSKELEDLLS | . ..... .| || || ||| ..| ||. ..| ..||.|. ||.|. ||| |. |..| .|. .|..|.| ||.. GFARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIR RLMTVIPKYRPTATEVMKHPWL .... |. ||...|...|.|. HMLQPHPCNRPHINEICHHCWM |
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| Kinase | MarkmA12.AA | Pkinase_Tyr | 39-180 | 25 | 7.9e-20 | 67.77 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 39-180
Range on HMM: 1-158/270
Sequence Identity: 25% (40 aa)
YKVIRTIGHGTFAKVLLAQHR----LTGTSVAIKVL--VKNKPW--FQEAMKEANILKKI-KHPNIVSLLQVIETKTRG---YLILELVEGQELYEYIKT
. ....|.| | .| .. . |.. ||.|.| .. .. |.||.|.|.. .|||||.|. |. . . |...|.... |..| ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
----SGHIEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLS
... |. .|| .. | . ....|||| |....... .|| ||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
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| Kinase | MarkmA12.AA | TyrKc | 39-287 | 21 | 2.4e-16 | 41.7 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 39-287 Range on HMM: 1-280/280 Sequence Identity: 21% (61 aa) YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMKEANILKKI--KHPNIVSLLQVIETK-------TRGYLILELVEGQELYEYIKTSGH . ....|.| | .| ... . . ||.|.| ... .. |.||.|..|. .||||| |. |. .. ....|.... | .|.. ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPG-------EILKE----HC---GAYAFGAPERFLGQRYDGTKS . .. .. .|| . | | ....|||| |....... .|| ||||| . . . . .. . ||| . .. ||| KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS DLGALGVVLHYMV-VGKVPFDS-----FINPELQRQVVAGVYPAHCGV---------SKELEDLLSRLMTVIPKYRPTATEVMKHPWL | . ||.. . |. | | |. ..| .| .. ..|. .. .. |. ||| .|. | . DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | MarkmA12.AA | TSSK | 39-69 | 29 | 7.6e-08 | 21.82 | In-house | 1-47 (289) | Show / Hide |
Range on Protein: 39-69 Range on HMM: 1-47/289 Sequence Identity: 29% (14 aa) YKVIRTIGHGTFAKVLLAQHRLTGTS----------------VAIKV |.| ..||||..||| .|... . ||||. YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKI |
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| Kinase | MarkmA12.AA | APH | 153-181 | 24 | 0.000195 | 16.01 | Pfam | 171-203 (248) | Show / Hide |
Range on Protein: 153-181 Range on HMM: 171-203/248 Sequence Identity: 24% (8 aa) GIVHRDLKPDNIMID-NKGNIK---IIDFGLST ...|.|..|.|.|.| . .. . .||.. .. CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDAC |
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| UBA_CAMKL | MarkmA12.AA | UBA_CAMKL | 307-344 | 39 | 9.2e-13 | 43.92 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 307-344 Range on HMM: 1-41/41 Sequence Identity: 39% (16 aa) DPDIVDAMQYI--GFRAKDIRESLTEEKF-NEMSAAYYLLE |..|.. |. . || ..|.||| . |. |...|.|||| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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