MarkmA11

Species: Mouse
Alias: MarkmA11
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MarkmA11.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 249 Kinase domain by global Sugen HMM Fasta, JSON
MarkmA11.NA RNA Sugen 1987 None Fasta, JSON
MarkmA11.AA Protein Sugen 508 None Fasta, JSON

Protein domain

Protein domains of MarkmA11.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MarkmA11.AA MARK 28-276 51 5.1e-160 526.58 In-house 1-262 (262) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-262/262
Sequence Identity: 51% (136 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLL---KNK-PCFQPAMKEANIMKKIKHPNIVSLLQVIE--TKTR-GYLIMELVEGQELYEYIKNS--GH
||...|.|||.|||| ||.|..||. ||.|..    .|.   ... | |..||||..||||..|..|||  |...  |||||...|.|||.|||.   |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKG--SIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMV
..|.|||.|| ||.||| |||  .|||||.||.||.||..|   |||||||.|....|||.| ..||.... |||.||.| |||.| | |.|||.||.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGKVPFDSFI--IPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
.|..|||     . ||. .||.|.|. || || |...|...|.||||..|||..|.|||||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase MarkmA11.AA CAMKL 28-276 40 4.2e-137 440.16 In-house 1-297 (297) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-297/297
Sequence Identity: 40% (121 aa)

YKVVRTLGHGTYAKVLLAQH-RLTGTPVAVKVLLKNKPCFQPAMK----------------EANIMKKIK---HPNIVSLLQVIETKTR------GYLIM
|....|||.|...|| ||.| |.||. ||.|.. |.| .  | ||                |..|||...   ||||..|..||||..        ||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVEGQE--LYEYIKNSGH----IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGS--IKIIDFGLSTQVKP-----GQLLHEHCGAYAFG
|...| |  |..||.. ||    ..|.|||..| ||.||| |||  ||||||.||.||..|..|.  |||||||.|.. .|     ||.|...|| ... 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFLW--KSYDGTKSDLWALGVILYYMVVGKVPFDSFIIP---------ELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
|||.|.   |.||| | | |..||||| ||.|..|||   ..         ...  .. . .| .. || ...||.. ...|||..|||. ..|.|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase MarkmA11.AA CAMK 33-276 24 1.6e-117 380.44 In-house 1-425 (425) Show / Hide
Range on Protein: 33-276
Range on HMM: 1-425/425
Sequence Identity: 24% (106 aa)

TLGHGTYAKVLLAQHRLTG------------TPVAVKVLLKN-----------------------------KPCFQPAMKEANIMKK-------IKHPNI
|||.|...|| |..|..|.            . ||.|.. |.                                 .  ..| .||||       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLLQVIET-------------------KTRGYLIM---ELVEGQEL----YEYIKNSGH---------------IEEDEARQIFLQILSAVGYCHGSGI
..|..|.|.                   ... |..|   |...| ||    ..||.  |.               ..|.|||..| ||.||| |||  .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPDNIMIDSK-----------------GSIKIIDFGLSTQVKP------------------------GQLLHEHCGAYAFGA-PELFLW------
|||||||.||..|..                 . |||||||......|                        ||.... ||  .. | ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KSYDGTKSDLWALGVILYYMVVGKVPFDSF-------------IIPELQMQILAGVYP-APCG---------------VSNE--------LKD
       | |.| |.| |..||||| |..|. ||..               ..||  .|..| |   |                 .|.|         ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLSLLMTVNPKYRPTVTEVMKHPWL
|.. ...|.|. |.|......|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase MarkmA11.AA AMPK 28-276 42 3.6e-97 289.01 In-house 1-254 (254) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-254/254
Sequence Identity: 42% (107 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVL----LKNKPCFQPAMKEANIMKKIKHPNIVSLLQVI-ETKTRGYLIMELVEGQELYEYIKNSGHIEED
| .  |.| ||. || .. | |||. ||.|.|    .|..   .   .|  |.|...||.|. | .|| ||.|  ...|| | | ||..||   | ..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPF
||.  | ||.|.| |||  .|||||||| |. .| . .||| |||||   | |..|   ||     |||.   | | |.. |.|  ||||| |. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
|   .|.|   |..|.|. |  .|.| |||.. . .|.|  | |. ....|||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase MarkmA11.AA S_TKc 28-276 33 5.1e-94 319.57 SMART 1-231 (231) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAMKEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEG--QELYEYIKNSGH------I
|...|..|.|...|| ...|. ||  ||.|..       . ...| .|.|| .||||| |. |... .. |..||...|   .|..|||. |.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

EEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGK
 | .|| .. ||..|. |||  ||.||||||.||..|.   |||.||||..|.      .  ||   . |||..   .|.. |.| |..|.||| |..|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

VPFDSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMK-------HPWL
 ||.    ... ....          | |.||... .....|. |||. |...       |||.
PPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MarkmA11.AA NuaK 28-276 40 2e-92 243.24 In-house 1-252 (252) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-252/252
Sequence Identity: 40% (102 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAM----KEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQELYEYIKNSGHIEEDE
|.. .||| ||| || ||  . ||  ||.|   |.|   .  |    .|  ||  . ||.|..   | | | .  ..||   | |||.|| . . . | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPFD
||..| || ||| |||  .|.|||||  ||. | .. .|| |||||   . ...||  ||   .  ||    . | |   | |.|||.|| || |  |||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

SFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
 .   .|  ||  | |  ||  |   . |   ...|||..| |. .. .|.|.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV

Kinase MarkmA11.AA QIK 28-276 38 1.4e-87 297.31 In-house 1-272 (272) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-272/272
Sequence Identity: 38% (104 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLK---NKPCFQPAMKEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQELYEYIKNSGH------
| . ||.| | .| | ||.|| | | ||.|.. |   ..  .|    |  ||| ..||.|. |.||.||.   |...|  .. |...|. . |.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSD
              ..|.|||..| ||.||| |||  .|||||||  ||..|.   |||.|||.|   |.||||   ||  .. |||.|. |.||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

LWALGVILYYMVVGKVPFDSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
 | .||.|| .| |. |||.  ...|.  .| | .  |  .| .. .|    ..|.|. | |.  ...|.|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase MarkmA11.AA Pkinase 28-276 32 1e-82 285.92 Pfam 1-293 (293) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAMK-----EANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQ----ELYEYIK--NS
|...|..| |....| ...|. ||  ||||.. | .   .  .      |. |||...||||| |. . |.|.. |..||..||     .|..||.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHI--EEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSI----KIIDFGLSTQ--VKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWAL
| .  .|.|.. ...|||... |||  ||.||||||.||.||..| |    ||.||||. |    ... ..  || . . |||. .  .|.|.|.| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYYMVVGKVPFDSF----------IIPELQMQILAGVYPAPCGVS-----------------NELKDLLSLLMTVNPKYRPTVTEVMKHPWL
|.|||.|. |. ||..           .| .  . .|   .| .| .|                  |.||... . ...|| ||| .....|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase MarkmA11.AA Ciliate-E2 28-276 23 5.5e-75 255.42 In-house 1-365 (365) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

YKVVRTLGHGTYAKVLLAQHRLTGT-----------------------PVAVKVL----LKNKPCFQPAMKEAN----------IMKKIKHPNIVSLLQV
||... .| |....| ........                         .|.|..    ....   .  |.| |          |.....||||. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--TKTRGYLIMELVEGQELYEYIKNS-----------GHIEEDEARQIFLQILS---------------AVGYCHGSG-IVHRDLKPDNIMIDSKGSI
 .  ...  ||.||...|..|..||||.           . . | |...|. |||.               |. |.|  . |.|||.||.||..     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLSTQVKP-----------GQLLHEH----------------------CGAYAFGAPELFLWKSYDG--------TKSDLWALGVILYYMVVGKV
||||||||.....           . ..  .                      || . . ||| .  |.||.        .|.|.|.||||||.|. || 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDSFIIPELQMQILAGVYPAPCG------------------VSNELKDLLSL----LMTVNPKYRPT-VTEVMKHPWL
||        | ||. . .  ||                   .|.| |||..     .. ..|. |.|   ....|||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase MarkmA11.AA SNRK 28-276 42 1e-74 244.0 In-house 1-254 (254) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-254/254
Sequence Identity: 42% (108 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNK---PCFQPAMKEANIMKKIKHPNIVSLLQVIETKTRGYLIMELVEGQELYEYI-KNSGHIEEDE
| . .|||.| .| | ||.|  ||  |||||. | |         ..|   || ..||||| |  ||.|.|. |||.|| .| ..|.|| |    ..|| 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSK-GSIKIIDFGLSTQVKPGQLLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPF
||. | ||. |. |||   .|||||||.|..   | | .|. ||| | . .||. |.  ||. |. |||. |  |||    |.|.|||||| .| |..||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DSFIIPELQMQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
.     |   .|.   |  |  ||.| .||.  ..  .|| | .. |.  |.|.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV

Kinase MarkmA11.AA Ciliate-E2-Unclassified 28-276 25 8.5e-73 248.15 In-house 1-352 (352) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAM-------KEANIMKKIK-------------------HPNIVSLLQVIETKTRGYLIM
||.....|.| ..|| ..||. ..   | | . |.. . |  .        |...|...|                   ||.|| .. . ..|   |..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELVEGQELYEYIKNSGH-----------------IEEDEAR-----QIFLQILSAVGYCHGSG-IVHRDLKPDNIMIDSKG---SIKIIDFGLSTQVK--
|..||..| .|||....                 ..| .|.     ..| |||..  |.| .. |.|||.||.||..|..|    |||||||.| . .  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------PGQLLHEHCGAYAFG----APELFLWKSYDG---TKSDLWALGVILYYMVVGKVPFDSFIIPE----------------LQMQILA
              . |...  || . .     |||..  . ||.    |.| |.||||||.|. |. ||..    .                |. .|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GVYP--------APCGVSNELKDLLS----LLMTVNPKYRPTVTEVMKHPWL
. .         .|...|.| ||...     .. .||..|.|  ....|||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase MarkmA11.AA TSSK 75-276 36 8.7e-66 214.89 In-house 68-289 (289) Show / Hide
Range on Protein: 75-276
Range on HMM: 68-289/289
Sequence Identity: 36% (81 aa)

IMKK-IKHPNIVSLLQVIETKT-RGYLIMELVEGQELYEYIKNS------GHIEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDF
||.| .|||||. ... .||   . |..||. |.  | |||...      | ..|..||. | |. ||| |||. ..||||||  ||  |  . ||..||
IMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDF

GLSTQVKPGQ------LLHEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGKVPFDS-----FIIPELQM-QILAGVYPA--PCGVSNELKDL
| .  .....      |.   || ||  ||| .. . ||. ..| |..||||| ||.|. |||        ... |. . .   .|.   |..| | |||
GFARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKV--CFPKPHSCWISQECKDL

LSLLMTVNPKYRPTVTEVMKHPWL
.. ... .|. ||...|...|.|.
IRHMLQPHPCNRPHINEICHHCWM

Kinase MarkmA11.AA Pkinase_Tyr 28-169 27 2.7e-21 72.72 Pfam 1-158 (270) Show / Hide
Range on Protein: 28-169
Range on HMM: 1-158/270
Sequence Identity: 27% (45 aa)

YKVVRTLGHGTYAKVLLAQHR----LTGTPVAVKVLLKNKPCFQPA-------MKEANIMKKI-KHPNIVSLLQVIETKTRG---YLIMELVEGQELYEY
 .  ..||.| . .| ..  .     |..|||||.| |.     .        |.||.|||.. .|||||.|. |.  . .    |..||....  |..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IKN----SGHIEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLS
 ..     ...   .  |. .|| ..  | .  ...||||   |....... .|| ||||.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase MarkmA11.AA TyrKc 28-276 22 1.1e-16 47.18 SMART 1-280 (280) Show / Hide
Range on Protein: 28-276
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTPVAVKVLLKNKPCFQPAMKEANIMKKI--KHPNIVSLLQVIETK-------TRGYLIMELVEGQELYEYIKNSGH
 .  ..||.| . .| ... .   ..||||.| ...   .  |.||.||.|.  .||||| |. |. ..          ...||....  | .|......
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-IEEDEARQIFLQILSAVGYCHGSGIVHRDLKPDNIMIDSKGSIKIIDFGLSTQVKPG-------QLLHE----HC---GAYAFGAPELFLWKSYDGTKS
 .  ..  .. .|| .   | |  ...||||   |....... .|| |||||  .. .       .  .     ..     .   ||| .  . .  |||
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DLWALGVILYYMV-VGKVPFDS-----FIIPELQMQILAG-VYPAPCG--------VSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL
| |. || .. .   |. |            |.  .. .|   | |           . |. .. .     .|. ||| .|.  |  .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase MarkmA11.AA TSSK 28-58 27 1.6e-08 24.05 In-house 1-47 (289) Show / Hide
Range on Protein: 28-58
Range on HMM: 1-47/289
Sequence Identity: 27% (13 aa)

YKVVRTLGHGTYAKVLLAQHRLTGTP----------------VAVKV
|.| ...|||.|||| .|... .                   ||.|.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKI

Kinase MarkmA11.AA APH 142-170 27 0.000386 15.0 Pfam 171-203 (248) Show / Hide
Range on Protein: 142-170
Range on HMM: 171-203/248
Sequence Identity: 27% (9 aa)

GIVHRDLKPDNIMID--SKGSIK--IIDFGLST
...|.|..|.|.|.|  . |     .||.. ..
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDAC

UBA_CAMKL MarkmA11.AA UBA_CAMKL 296-333 39 1.4e-13 46.82 In-house 1-41 (41) Show / Hide
Range on Protein: 296-333
Range on HMM: 1-41/41
Sequence Identity: 39% (16 aa)

DPDIVDAMQYI--GFQAKDIRESLTKEKF-NEMSAAYYLLE
|..|.. |. .  ||. ..|.||| . |. |...|.|||| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL

UBA MarkmA11.AA UBA 296-333 18 0.000269 21.52 SMART 1-38 (38) Show / Hide
Range on Protein: 296-333
Range on HMM: 1-38/38
Sequence Identity: 18% (7 aa)

DPDIVDAMQYIGFQAKDIRESLTKEKFNEMSAAYYLLE
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YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS