Gene MARK3 (Mouse)

MARK3

Species: Mouse
Alias: Mark3, MARK3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MARK3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
MARK3.NA RNA Sugen 3415 None Fasta, JSON
MARK3.AA Protein Sugen 753 None Fasta, JSON

Protein domain

Protein domains of MARK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MARK3.AA MARK 56-307 58 3.1e-182 600.28 In-house 1-262 (262) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-262/262
Sequence Identity: 58% (154 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNP-TSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKT-LYLIMEYASGGEVFDYLVAH--GR
|..|||||.|..||||||.|..|||.|||||..|..||.  ......||..||| |.||||.|||.|||  ||.. .|||||||||||..||..||  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADM--NIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV
..|.|||. ||||||||.|||.|.|||||.|.||.|.|...  ||||.|||||.... |.||.||||.|||.|||.|..|.||||.||.|||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

SGSLPFDGQN--LKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
.|..||||..  .|||....|||||.||...|..|.||..|.|..|| .| |.|.|||..|.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase MARK3.AA CAMKL 56-307 49 8.9e-173 555.85 In-house 1-297 (297) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-297/297
Sequence Identity: 49% (148 aa)

YRLLKTIGKGNFAKVKLARH-ILTGREVAIKIID--KTQLNPTSLQK-----------LFREVRIMKILN---HPNIVKLFEVIETEKT------LYLIM
||..||.|||.|.|||||.| ..||..|||||||  |....| ....           ..||..||| ||   ||||.||.|||||...      .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--VFDYLVAH----GRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADM--NIKIADFGFSNEFT-V----GSKLDTFCGSPPYA
||.||||   |||.|.|    |||.|.|||  ||||||||.|||...|||||.|.||.||| ..  ||||.||||||... .    | ||.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFQG--KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK---------ELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
|||.|||  |.||||.||.||.|||||..| | ||||.....         ....... ....|....| ||..|... |. || || |..|||...| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase MARK3.AA QIK 56-307 58 2.2e-167 562.37 In-house 1-272 (272) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-272/272
Sequence Identity: 58% (160 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGR------
| . .|||||||| ||||||. |  .||||||||.||. . |||..||| ||| |.||.|.||..|.||.. .|...||.|.|| ||||..|||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------MKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVD
              |.|.||| .| ||.|||.|||.. ||||||||||.|||..|||||||||||| |. |  | |.||||||||||.|.||.||||.||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
.||.||.|| ||.|.|||||..|..||.||| ||.||||.||.||| | .. ||..| .| | .||.. ||.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase MARK3.AA AMPK 56-307 50 1.8e-147 440.84 In-house 1-254 (254) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-254/254
Sequence Identity: 50% (129 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEVI-ETEKTLYLIMEYASGGEVFDYLVAHGRMKEK
| . ||||.| | |||.. ||||| .|||||..|. .   . . .. ||..|.|...||.|..|.||| ||.. ....|||.|||| ||| | |||..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
||.  | ||.|.| |||.  ||||||| ||||||...||||.||| ||  . | .| | |||| |||||. .||.| |||||.|| ||||| .. | |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
| .|  .|  ... |.| || ..|.....|.|. |  .|.|| | ..|... | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase MARK3.AA CAMK 61-307 31 1.4e-145 472.52 In-house 1-425 (425) Show / Hide 
Range on Protein: 61-307
Range on HMM: 1-425/425
Sequence Identity: 31% (134 aa)

TIGKGNFAKVKLARHILTG------------REVAIKIIDKTQLN--------------------------PTSLQKLFREVRIMKI-------LNHPNI
|.|.|.|.||||..|..|.            ..||||||||..|                           | ......||..|||        |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLFEVIE------------TEKT--------LYLIM---EYASGG----EVFDYLVAH---------------GRMKEKEARAKFRQIVSAVQYCHQKR
.||.||.|            | ..        .|..|   ||.|||    ..|||.|.|               ||..|.|||  ||||.|||.|||.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKAENLLLDADM-----------------NIKIADFGFSNEFTV------------------------GSKLDTFCGSPPYAA-PELFQG-----
||||||| ||.||| ..                 ||||.||||.|.|.                         | |. ||||.|.|.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYDGPEVDVWSLGVILYTLVSGSLPFDGQ-------------NLKELRERVLRGKYR-IPFYMST-----------------------DCE
        |.|.||..|.||.|||||....| .||.|              |..|| |....|||. .|.|.|.                       .| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLLKRFLVLNPVKRGTLEQIMKDRWI
.|... |. .| || |.||.... |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MARK3.AA NuaK 56-307 49 6.4e-144 381.51 In-house 1-252 (252) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-252/252
Sequence Identity: 49% (126 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKE
|...|| ||| . |||||. . |||||||| | |     .  . .  ||..||  ||||.|.. .|| |    . ..|||||||| .||.   ... |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD
||  |||||||| |||. ||.||||| || |||.. |.|||||| || .  .  | |||||| || ||   |. | ||||| |||||.|||.| |..|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
|.. |.|   . .|.|. |   |. |. |    |  || .| |...| .  |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase MARK3.AA NIM1 56-307 44 8.20000000001e-121 356.61 In-house 1-258 (258) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-258/258
Sequence Identity: 44% (114 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIID--KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEK
||. . || ||| ||||. | ||   |||||.|  || .    .  | ||.  |  ..|||||.|.||.||   ..|.||||.||| . .    | . | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTV----GSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG
..   | ||||||.  | . |||||.|||| .. .   .|..|||||         . .|.|||||||||||||||   | |. |||| ||..||  . |
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

SLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
  ||      ..   .| |.| || | |  |  | .. |   |  | | .|.|.. |.
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase MARK3.AA BRSK 56-307 51 6.1e-113 381.51 In-house 1-254 (254) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-254/254
Sequence Identity: 51% (132 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLN--PTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEK
||| || |||   .|||  |  ||. |||||| |  |   .  |.|  ||. |||  .||.. |...| |. | ||||.|. |||| |||||  ||.. |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
|||  ||||.||. .|| . | ||||| |||||| . ||||||||       .. |.| |||| || ||  .| ||||   |||| ||||| |  | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
|  || .| |.| || . .| .   || .||.  .  .| || .|..| |  | 
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase MARK3.AA S_TKc 56-307 36 4.4e-111 376.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASG--GEVFDYLVAHGR----
|..|..|||| |.||...||. |||.||||||.         ... ||..|.|  .|||||||..|... . ||..|||..|  |..|||.. .||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--MKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLV
  . | .||  ..||..|..|||...|.||||| ||.|||   .|||.|||.. ..      .||||.| | |||..   .|.....|.||.|.||| ..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMK-------DRWI
.|  ||.  ..... ....          | .. ..... |. .| || |  ....       . |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MARK3.AA SNRK 56-307 48 7.69999999999e-107 350.92 In-house 1-254 (254) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-254/254
Sequence Identity: 48% (124 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGR-MKEKE
| | ||.|.| || ||||||. ||  ||.|.||||..   |  .||.||| ||.  |||||.|.|||.|   ||||.|   |....||.. | . ..|. 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMN-IKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF
||  |.||. |..||||...|||||| || .    .  .|. ||||||.|  | ||.|.|||  |.|||.  | .|| | ||.|||||||| || | .||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
.  |  |   ...  || .|  .|..| .|... || .| || .||.|    |.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase MARK3.AA TSSK 56-307 36 7.89999999999e-107 351.65 In-house 1-289 (289) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-289/289
Sequence Identity: 36% (106 aa)

YRLLKTIGKGNFAKVKLARHILTGRE----------------VAIKIIDKTQLNPTSLQK-LFREVRIMKI-LNHPNIVKLFEVIETEK-TLYLIMEYAS
| . |.||.|..|||..|..  . ..                |||||||..   .  |.| | ||  ||.. |.||||....| .||.    |..||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGEVFDYLVAH------GRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGS------KLDTFCGSPPYAAPELF
.| ...|  ..      |...|..||. |||.||||.||| . .|||||| ||.||| . |||..||||..... ..      .. |||||  ||||| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

QGKKYDGPEVDVWSLGVILYTLVSGSLPFDG--QNLKELRERVL-RG-KYRI--PFYMSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
.|..||.  .||||.|||||..| |..|||   .|.. . ...  .. ....      |..| .|... | ..| .| ....|... |.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase MARK3.AA Pkinase 56-307 34 2.8e-105 360.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR--EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGG----EVFDYLV--AH
|.....||.|.|..|....|. ||..||.|||.|   ..  .| ..|  |..||| |||||||.|... |... .|..|||. ||    . |||.   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRM--KEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNI----KIADFGFSNE--FTVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL
|..   |.|..  ..||.....|||...|.||||| ||.|.| ...|    ||.|||..       .| ..||||.|.|.|||. .| .|.||.||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYTLVSGSLPFDGQ------NLKELRERVLRGKYRIPFY---------------------MSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI
|.||| ...| .||.|.      . ... .|....... ...                     .| .|  ..|. | ..| || | |||... |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MARK3.AA TyrKc 56-306 25 1.4e-29 105.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 56-306
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL--NHPNIVKLFEVIETE-------KTLYLIMEYASGGEVFDYLVA
 .|.|..| |.| .| ... .   ..||.| . .       .. . || |||. |  .|||||.|. |. ..       . |...|||...|   ||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGR-MKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG------SKLDTF----CGS--PPYA--APELFQGKKYDG
|..  . |.      || .  .| |.|...|||| | | |....  .||.||| | . . .      ..  .     .|    |.   ||| .. .|.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

PEVDVWSLGVILYTLVS-GSLPFDG-----QNLKELRERVLRG-KYRIPFY--------MSTDCENLLKRFLVLNPVKRGTLEQIMKDRW
.. |||| || .. . . |  |  |      . .|..|.| .|   ..| .        ....  .. |.    .| .| | ..| ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase MARK3.AA Pkinase_Tyr 56-198 31 6.6e-28 95.14 Pfam 1-156 (270) Show / Hide 
Range on Protein: 56-198
Range on HMM: 1-156/270
Sequence Identity: 31% (49 aa)

YRLLKTIGKGNFAKVKLARHI----LTGREVAIKIIDKTQLNPTS--LQKLFREVRIMKIL-NHPNIVKLFEVIE-TEKT--LYLIMEYASGGEVFDYLV
 ...|..|.|.| .|....       |. .||.|.. | .  .    .....||..||| | .|||||.|  |.   ..   .|..|||. .|   ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AH----GRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFG
.|    .. . |.     .|| .. .| ..|...|||| | | |.. .. .||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase MARK3.AA Pkinase_Tyr 235-273 34 0.032582 8.12 Pfam 196-236 (270) Show / Hide 
Range on Protein: 235-273
Range on HMM: 196-236/270
Sequence Identity: 34% (14 aa)

DVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIP
|||| || .. ... |  | . |    |. |.. .  || |
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP
UBA_CAMKL MARK3.AA UBA_CAMKL 328-365 48 1.3e-16 57.61 In-house 1-41 (41) Show / Hide 
Range on Protein: 328-365
Range on HMM: 1-41/41
Sequence Identity: 48% (20 aa)

DQKRIDIMVGM--GYSQEEIQESLSKMKY-DEITATYLLLG
|...|..|. |  |.. ||| |||.. || ..|||||.||.
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL
UBA MARK3.AA UBA 328-365 23 4.2e-11 44.13 SMART 1-38 (38) Show / Hide 
Range on Protein: 328-365
Range on HMM: 1-38/38
Sequence Identity: 23% (9 aa)

DQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLG
....|| ...||...||....|.. .... .|...|. 
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS
UBA MARK3.AA UBA 327-363 18 9e-06 24.7 Pfam 1-38 (38) Show / Hide 
Range on Protein: 327-363
Range on HMM: 1-38/38
Sequence Identity: 18% (7 aa)

SDQKRIDIMVGM-GYSQEEIQESLSKMKYDEITATYLL
.|.. .. .. | |.| .. .. | . .... .|.. |
IDEEMVKQLMEMTGFSMMQCKKALRACNNNVERAVEWL
KA1 MARK3.AA KA1 707-753 43 1.3e-23 82.42 Pfam 1-48 (48) Show / Hide 
Range on Protein: 707-753
Range on HMM: 1-48/48
Sequence Identity: 43% (21 aa)

AENLVQWEMEVCKLP-RLSLNGVRFKRISGTSIAFKNIASKIANELKL
 .. |..|..|||.| ||.|.||.|||.|| . ..|....|| .|..|
EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL