Gene KSR2 (Mouse)

KSR2

Species: Mouse
Alias: KSR2
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: RAF
Subfamily: KSR

Sequence

Name Sequence Type Origin Length Description Download
KSR2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON
KSR2.AA Protein Sugen 950 None Fasta, JSON
KSR2.NA RNA Sugen 2868 None Fasta, JSON

Protein domain

Protein domains of KSR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1 KSR2.AA C1 412-457 22 1.4e-10 42.41 SMART 1-61 (61) Show / Hide 
Range on Protein: 412-457
Range on HMM: 1-61/61
Sequence Identity: 22% (14 aa)

IKHRFSTKYWMSQTCTVCGKGMLF---------GLKCKNCKLKCHNKCTKEAP--------PC
..... ..   . .| .|.| . .         |..| .||.|||.|| . .|        .|
HHWHWWRF--KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_1 KSR2.AA C1_1 414-457 25 4e-06 26.04 Pfam 1-51 (55) Show / Hide 
Range on Protein: 414-457
Range on HMM: 1-51/55
Sequence Identity: 25% (13 aa)

HRFSTK--YWMSQTCTVCGKGM-----LFGLKCKNCKLKCHNKCTKEAPPC
|..  .  . ..  | .||. .     . |.|| .|...||..| . .||.
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPE
Kinase KSR2.AA KSR 667-929 58 2.3e-206 691.89 In-house 1-272 (272) Show / Hide 
Range on Protein: 667-929
Range on HMM: 1-272/272
Sequence Identity: 58% (160 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIE-RDNEDQ-LKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKG-RTLYSVVRDAKIVLDVNK
|..||.||.||||.|..|.|||||||.|.... ...|.. |..||.|||.|..|||||.||||||||.||||||..||||| .|||.........||.|.
LKYGECIGQGRFGKVHRGHWHGEVAIKLYYMDHIHDEHHDLEDFKDEVMMYKNTRHENIVLFMGACMNPPHLAIVMSLCKGSQTLYHHIHVRREKLDMNR

TRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDN-GKVVITDFGLFSISGVLQAGRRDDKLRIQNGWLCHLAPEIIRQLSPDTEEDK---LPFSKHSDVF
|.||||.|..||||||||||.||||||||.||.| |||||||||||||...|....|.|.|.|..||||.||||.||...|...|..   ||||.||||.
TMQIAQQICQGMGYLHAKGIIHKDLKSKNIFYENKGKVVITDFGLFSITRLLHCCQREDHLCIPHGWLCYLAPELIRAMRPNYDEYQCMCLPFSHHSDVY

ALGTIWYELHAREWPFKTQPAEAIIWQMGTG--MKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
|.||||||....|||||.|.||.|||||..|  |...|.....|.|...||..||..|..|||||...|.||
AFGTIWYEMICGEWPFKYQCAESIIWQMCQGEGMRQVLRNVQCGREMKEILMMCWSYEPQERPTFQDIMKML
Kinase KSR2.AA RAF 667-929 50 4.4e-175 587.94 In-house 1-275 (275) Show / Hide 
Range on Protein: 667-929
Range on HMM: 1-275/275
Sequence Identity: 50% (138 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIE-RDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSP--PHLAIITSLCKGRTLYSVVRDAKI-VLDVN
..||| ||.||||.||.|.|||.||....... ...|.||.|||.|||.|..|||||.|||||.||.|  ||.||.|..|||.|||......|   .|.|
VQIGERIGQGRFGTVYRGHWHGDVAVKTLNMKYPTPEHQLQAFKNEVMMYKKTRHENIVLFMGYCMKPDNPHYAIVTQWCKGSTLYHHIHVQKTEKFDMN

KTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGKV-VITDFGLFSISGVLQAGRRDDKLRIQNGWLCHLAPEIIRQLSPDTEEDK---LPFSKHSDV
.|.||||.|..||.|||||.|.|.||||||.|..|||| ||||||||.........||...|....||.|..|||.||...||..|..   .|||..|||
WTIQIAQQICQGMDYLHAKNIIHRDLKSKNIFLHNGKVVVITDFGLFTVKRCRWCKRRKQQLCQPHGWICWMAPEVIRMMRPDWDEYQCDCNPFSFQSDV

FALGTIWYELHAREWPFK-TQPAEAIIWQMGTG---MKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
.| ||.||||.|.|||.. .|..|.|||....|   |....... ..||....|..||....||||.|...|.|.
YAFGTVWYELMAGEWPYQHIQWHEQIIWMVCRGYLRMDRSKARVQCPKEMKELLMECWSYQPEERPSFQQIMKMI
Kinase KSR2.AA RAF 667-931 34 1.1e-80 261.35 In-house 1-282 (282) Show / Hide 
Range on Protein: 667-931
Range on HMM: 1-282/282
Sequence Identity: 34% (97 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKA---FKREVMAYRQTRHENVVLFMGACMSPPH---LAIITSLCKGRTLYSVVRDAKI--V
..... || |.|| || |.|||.||.. . ..    .|..|   || || .|..||| |..|||| .|| |.   .||.|  | . .||  .  ..    
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMG-YMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREK

LDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNG-KVVITDFGLFSISGVLQAGRRDDKLRIQNGWLCHLAPEIIRQLSPDTE-----EDKLPF
.| ... .|.. . .|| ||||| |.| ||||.|.| ... .|.|.||||  .   .   |.. .. . ..|   .|||.||.|  |        |..|.
FDMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVK-TRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPY

SKHSDVFALGTIWYELHAREWPF--KTQPAEAIIWQMGTG-MKPNLSQI--GMGKEISDILLFCWAFEQEERPTFTKLMDMLEK
|  |||.. |.. ||| .|. |.    .  . ||.  | | ..| ||..   . | .   .. ||.|..|||| | ... ... 
SFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase KSR2.AA TKL 673-929 21 7.9e-75 254.91 In-house 1-364 (364) Show / Hide 
Range on Protein: 673-929
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

IGKGRFGQVYHGRWHG-----------EVAIRLIDIERDNEDQL-------------------------KAFKREVMAYRQTRHENVVLFMGACMSPPH-
||.|.||.||.|.|.|           .||.  . .. |.|. .                         . ...|.|  ...||.|.|.|||.|..||. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHA--------KGILHKDLKSKNVFYD-NGK--------------V
            |.|.. .|.| .|....         ... ..|..| .|| |||.        ..|.| ||||||.. | |..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

VITDFGLFS-ISGVLQ--------------AGRRDDKLRIQNGWLCHLAPEIIRQLSPDTEE-------DKLPFSKHSDVFALGTIWYELHAREWPFKTQ
 |.||||   .|.  .              . ... ..  | |.....|||..|.  ..||         ....|. .||.. | ...|. .|..|.. .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

PAE---------AIIWQMGT-GMKPNLS-----------QIGMGKEISDILLFCWAFEQEERPTFTKLMDML
| .         ..... .  |..| .               . .......  ||. . |.||.|..... |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase KSR2.AA Pkinase 667-929 20 1.6e-40 144.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 667-929
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

LEIGELIGKGRFGQVYHGRWHGE---VAIRLIDIERDNEDQLKAFKR--EVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGR----TLYSVVR-DAK
..||. ||.| ||.||.....|.   ||.  |. ..........  |  |.   .  .|.|.| . .......|. ... .| |      |..... ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IVL--DVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYD-NGKV----VITDFGL---FSISGVLQAGRRDDKLRIQNGWLCHLAPEIIRQLSPDTE
 ..  . .  . .. .|..|. |.|..||.| |||. |...| || .     |.||||   |.         ..  .    | .  .|||.||       
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIR-------

EDKLPFSKHSDVFALGTIWYELHAREWPFKTQ------PAEAIIWQMGT----GMKPNLSQIG---------------MGKEISDILLFCWAFEQEERPT
 .  . .. .|....| | ||.  .. ||. .         ..| . .        |... |                . .|  |..  |...  ..|||
-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

FTKLMDM--L
.. ..    .
AEQILQHPWF
Kinase KSR2.AA S_TKc 667-929 21 8.9e-35 122.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 667-929
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

LEIGELIGKGRFGQVYHGRWHG---EVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKG--RTLYSVVRDAKIV---
 ||...|||| ||.|| .|...   .|||  |.         . ..||.   .. .|.|.| . ... .  || ... .| |   .|... .. .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGKVVITDFGLFSISGVLQAGRRDDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSK-H
  ..   .| ....|.... |.| .||.| |||  |.. |.  . |.||||  .             . . | .  .|||..            ...|  
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------------TTFCGTPWYMAPEVL------------GYGKCK

SDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMD---------ML
.|. ..| | ||. ... ||     .... ..|             .|  |..  |. .. |.|||  ...           .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase KSR2.AA TKL-Unique 669-807 33 1.6e-34 119.24 In-house 1-163 (290) Show / Hide 
Range on Protein: 669-807
Range on HMM: 1-163/290
Sequence Identity: 33% (54 aa)

IGELIGKGRFGQVYHGRWHGE-VAIRLIDI-ERDNEDQLKAFKREVMAYRQTR-HENVVLFMGACM----SPPHLAIITSLCKGRTLYSVVR--------
....|| | .||||.| |.|. |||  . . |  . . .. |..||      . |.|.|..||.||    .||.. |... | | .||.|          
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-DAKIVLDVNKTRQIAQEIVKGMGYLHAKG--ILHKDLKSKNVFYDNG------KVVITDFGL
   .. |. ..  ..|. |..|| ||| ..  |.| ||||.|.  ||.      .. | ||||
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGL
Kinase KSR2.AA Dicty4 667-807 37 4.2e-34 111.26 In-house 1-160 (277) Show / Hide 
Range on Protein: 667-807
Range on HMM: 1-160/277
Sequence Identity: 37% (60 aa)

LEIGELIGKGRFGQVYHGRWHG-EVAIRLIDIERDN--EDQLKAFKREVMAYRQTRHENVVLFMGACM----SPPHLAIITSLC-KGRTLYSVVRD----
. |...|||| ||.|| |.| | |||. .     .|  |. |..|..||    . || |..||||||      |. . | | .. || .|||. .|    
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKG-NLYSLLHDKPSE

--AKIVLDVNKTRQ---IAQEIVKGMGYLHAKG--ILHKDLKSKNVFYDNGKVV-ITDFGL
   .| ||    ..   .|  ...|| .||.    |.| |||| |   |  ..| ..||||
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGL
Kinase KSR2.AA Pkinase_Tyr 667-807 29 1.9e-32 110.49 Pfam 1-157 (270) Show / Hide 
Range on Protein: 667-807
Range on HMM: 1-157/270
Sequence Identity: 29% (47 aa)

LEIGELIGKGRFGQVYHGRWH-------GEVAIRLIDIERDNEDQ--LKAFKREVMAYRQT-RHENVVLFMGACM--SPP-HLAIITSLCKGRTLYSVVR
...|. .|.| ||.||.|.|.        .||.  .  |   ..|  ...| ||.   .|  .|.|.| ..|.|.  . | .. |.. ....  |..  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DA---KIVLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYD-NGKVVITDFGL
.    |  |..    |....| ||| ||..|.. | ||  .|.  . |..| |.||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL
Kinase KSR2.AA DRK 667-807 37 4.6e-30 99.04 In-house 1-146 (258) Show / Hide 
Range on Protein: 667-807
Range on HMM: 1-146/258
Sequence Identity: 37% (55 aa)

LEIGELIGKGRFGQVYHGRWHG-EVAIRLIDIERDN-EDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITS-LCKGRTLYSVVRDAKIVLDVNK
  ||  ||.| .|.|. | | | .||.        | |. |. |.||.    | || |...|||.|  ||   |..  . .|  ||..  | .| .|   
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRG-SLYNILHDESIEMDWPL

TRQIAQEIVKGMGYLHAKG--ILHKDLKSKNVFYDNG-KVVITDFGL
  |..  . ||| |||     |.| |||| |   |   .| . ||||
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL
Kinase KSR2.AA MLK 667-808 28 3.8e-28 94.8 In-house 1-180 (291) Show / Hide 
Range on Protein: 667-808
Range on HMM: 1-180/291
Sequence Identity: 28% (51 aa)

LEIGELIGKGRFGQVYHGRWHG-E-----VAIRLIDIER----DNEDQLKAFKREVMAYRQTRHEN----VVLFMGACMSPPH-LAIITSLCKGRTLYSV
... | ||.| ||.|. |||.. .     ||.. ....     | . . ..|..|..  |  .|.|    .. |.|.| .||. ..|..  | |  ||.|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

VRDAK-------------IVLDVNKTRQIAQEIVKGMGYLHAKG---ILHKDLKSKNVFYD-------NGKVVITDFGLF
 ..|.             .| |.    ..|  . .|| |||..    | | ||||.|.  |       .|...|.|||..
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS
Kinase KSR2.AA TK 667-807 12 2.1e-25 81.47 In-house 1-297 (486) Show / Hide 
Range on Protein: 667-807
Range on HMM: 1-297/486
Sequence Identity: 12% (38 aa)

LEIGELIGKGRFG---QVYHGRWHG----------------------------EVAIRLID--IERDNEDQLK-------------AFKREVMAYRQ--T
...|. .|.| ||   .|| |.|.|                            .||.  .    . . |...              .. .| .  ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHENVVLFMGACMSP------------PHLAIITSLCKGRT----LYSVVRD-AKIVLDVNKTRQ-----------------------------------
.|.|.| . |.|. .            ... |.. ....      | .  |.  .   .   . .                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IAQEIVKGMGYLHAK------GILHKDLKSKNVFYDNGK------------VVITDFGL
                                      ... | .|| |||.|      .. | ||   |.  ....            . |.||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL
Kinase KSR2.AA MLK 667-793 34 4.9e-25 79.49 In-house 1-134 (280) Show / Hide 
Range on Protein: 667-793
Range on HMM: 1-134/280
Sequence Identity: 34% (47 aa)

LEIGELIGKGRFGQVYHGRWHGE---VAIRLIDIERDNEDQ---LKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLD
|.| |.|| |.||.|| . |.||   | .   | |.|       .   ..|   .   .|.|..   |.|...||| ..  .|.|  |  |.. ..| ..
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQDPEQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLEDPHLCLVMEYCRGGSLNRVCAGKRIPPH

V--NKTRQIAQEIVKGMGYLHAKG---ILHKDLKSKNV
|  |   |||    .|| |||  .   |.| ||||.|.
VLVNWAVQIA----RGMNYLHNEAPVPIIHRDLKSSNI
Kinase KSR2.AA TyrKc 667-929 22 4.3e-16 37.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 667-929
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQT--RHENVVLFMGACMSP-------PHLAIITSLCKGRTLYSVVRDAKI
.. |. .| | ||.||.|.|  .||.  .  .      ...| ||    ..   .|.|.| . |.|...       . | |.. ....  | .  |. . 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

VLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGK-VVITDFGLFSISGVL-QAGRRDDKLRIQNGWLCH-------LAPEIIRQLSPDTEED
 | . .  ...  | .|| ||| |.. | ||   |. ..... | |.||||    .   |.| ..|  | . .  ..       .||| |         .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---------N

KLPFSKHSDVFALGTIWYELHAR-EWPFKT-----QPAEAIIWQMGTGMKPNLSQIG-------MGKEISDILLFCWAFEQEERPTFTKLMDML
.  |.  |||.. |   .|.  . . |         ... .| .  .|. .   . .       . .|. .| . ||... |.||||. . . .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase KSR2.AA TK 902-929 39 3.2e-07 19.46 In-house 459-486 (486) Show / Hide 
Range on Protein: 902-929
Range on HMM: 459-486/486
Sequence Identity: 39% (11 aa)

KEISDILLFCWAFEQEERPTFTKLMDML
.|. |... ||... |.||||. | ..|
EEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase KSR2.AA TKL-Unique 833-929 21 6.9e-07 20.53 In-house 193-290 (290) Show / Hide 
Range on Protein: 833-929
Range on HMM: 193-290/290
Sequence Identity: 21% (23 aa)

LAPEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREW------PFKTQPAEAIIWQMGT---GMKPNLSQIGMGKEISDILLFCWAFEQEERPTFT
.|||..|..          .|..|||.. |.. .|.  |.       |..    |...    .   .  | ...  . ||..|..  ||. . ..||.|.
MAPEVLRMNF-------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNH-CPKEYRDLIQQCWHHDPSQRPSFD

KLMDML
     |
EIIHRL
Kinase KSR2.AA MLK 852-929 25 2e-06 16.99 In-house 203-280 (280) Show / Hide 
Range on Protein: 852-929
Range on HMM: 203-280/280
Sequence Identity: 25% (20 aa)

FSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQIGMG--KEISDILLFCWAFEQEERPTFTKLMDML
.|| |||   | .  ||  .| |..   . |. ..     | .|. |.       . ..  ||. .  .||.|..... |
WSKGSDVWSYGVLLWELLTGEVPYRGIDPLAVAYGVAM-NKLTLP-IPSTCPEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase KSR2.AA MLK 834-929 23 5e-06 17.07 In-house 201-291 (291) Show / Hide 
Range on Protein: 834-929
Range on HMM: 201-291/291
Sequence Identity: 23% (23 aa)

APEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREWPFK-TQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
|||.| |          ..|. .||.  | . .|...|| |.|  . . ||.|...   .     ..  . ..  .  ||  . ..||.|   .  |
APEVIQQ------FRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase KSR2.AA Pkinase_Tyr 902-929 39 4.1e-05 17.93 Pfam 243-270 (270) Show / Hide 
Range on Protein: 902-929
Range on HMM: 243-270/270
Sequence Identity: 39% (11 aa)

KEISDILLFCWAFEQEERPTFTKLMDML
.|| |... ||... |.||||. .  .|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL